SCOPUS 정보 검색 플랫폼

ChemBioChem

Volumn 13, Issue 11, 2012, Pages 1628-1634

Targeting Tumour Proliferation with a Small-Molecule Inhibitor of AICAR Transformylase Homodimerization

(6) Spurr, Ian B a Birts, Charles N b Cuda, Francesco a Benkovic, Stephen J c Blaydes, Jeremy P b Tavassoli, Ali a,b

a UNIVERSITY OF SOUTHAMPTON (United Kingdom)

b UNIVERSITY OF SOUTHAMPTON (United Kingdom)

c PENNSYLVANIA STATE UNIVERSITY (United States)

Author keywords

AICAR transformylase; ATIC; Cancer; Peptides; Protein protein interaction inhibitors

Indexed keywords

ARGINYLTYROSINE DIPEPTIDE; CYCLOPEPTIDE; ENZYME INHIBITOR; HEXAPEPTIDE; INOSINE MONOPHOSPHATASE CYCLOHYDROLASE; PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYLTRANSFERASE; SMALL MOLECULE TRANSPORT AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CANCER THERAPY; CELL COUNT; CELL DIVISION; DIMERIZATION; DRUG ACTIVITY; DRUG DESIGN; DRUG DETERMINATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MOLECULARLY TARGETED THERAPY; NONHUMAN; PRIORITY JOURNAL; TUMOR GROWTH;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CATALYTIC DOMAIN; CELL COUNT; CELL DIVISION; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; FEMALE; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MCF-7 CELLS; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; PEPTIDES, CYCLIC; PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYLTRANSFERASE; PROTEIN MULTIMERIZATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84864011829 PISSN: 14394227 EISSN: 14397633 Source Type: Journal
DOI: 10.1002/cbic.201200279 Document Type: Article

Times cited : (58)

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