Erratum: Expression of Concern: Accumulating Microglia Phagocytose Injured Neurons in Hippocampal Slice Cultures: Involvement of p38 MAP Kinase (PLoS ONE (2012) 7:7 (e40813) 10.1371/journal.pone.0040813);Accumulating microglia phagocytose injured neurons in Hippocampal slice cultures: Involvement of p38 MAP kinase

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Katayama, Takahiro ^a   Kobayashi, Hayato ^a   Okamura, Toshiyuki ^a,b   Yamasaki Katayama, Yuko ^b   Kibayashi, Tatsuya ^a   Kimura, Hiroshi ^c   Ohsawa, Keiko ^d   Kohsaka, Shinichi ^d   Minami, Masabumi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CLODRONIC ACID; ENHANCED GREEN FLUORESCENT PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; N METHYL DEXTRO ASPARTIC ACID; PROPIDIUM IODIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; BRAIN SLICE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; FLUORESCENCE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MICROGLIA; MOUSE; NERVE CELL LESION; NONHUMAN; PHAGOCYTOSIS; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; STRATUM RADIATUM; TIME LAPSE IMAGING;

EID: 84863992162     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0278796     Document Type: Erratum

References (21)

1. Nimmerjahn A, Kirchhoff F, Helmchen F, (2005) Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 308: 1314-1318.
2. Davalos D, Grutzendler J, Yang G, Kim JV, Zuo Y, et al. (2005) ATP mediates rapid microglial response to local brain injury in vivo. Nat Neurosci 8: 752-758.
3. Wake H, Moorhouse AJ, Jinno S, Kohsaka S, Nabekura J, (2009) Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals. J Neurosci 29: 3974-3980.
4. Hanisch UK, Kettenmann H, (2007) Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci 10: 1387-1394.
5. Witting A, Muller P, Herrmann A, Kettenmann H, Nolte C, (2000) Phagocytic clearance of apoptotic neurons by Microglia/Brain macrophages in vitro: involvement of lectin-, integrin-, and phosphatidylserine-mediated recognition. J Neurochem 75: 1060-1070.
6. Hirt UA, Leist M, (2003) Rapid, noninflammatory and PS-dependent phagocytic clearance of necrotic cells. Cell Death Differ 10: 1156-1164.
7. Hsieh CL, Koike M, Spusta SC, Niemi EC, Yenari M, et al. (2009) A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia. J Neurochem 109: 1144-1156.
8. Stefano L, Racchetti G, Bianco F, Passini N, Gupta RS, et al. (2009) The surface-exposed chaperone, Hsp60, is an agonist of the microglial TREM2 receptor. J Neurochem 110: 284-294.
9. Gahwiler BH, Capogna M, Debanne D, McKinney RA, Thompson SM, (1997) Organotypic slice cultures: a technique has come of age. Trends Neurosci 20: 471-477.
10. Holopainen IE, (2005) Organotypic hippocampal slice cultures: a model system to study basic cellular and molecular mechanisms of neuronal cell death, neuroprotection, and synaptic plasticity. Neurochem Res 30: 1521-1528.
11. Hirasawa T, Ohsawa K, Imai Y, Ondo Y, Akazawa C, et al. (2005) Visualization of microglia in living tissues using Iba1-EGFP transgenic mice. J Neurosci Res 81: 357-362.
12. Stoppini L, Buchs PA, Muller D, (1991) A simple method for organotypic cultures of nervous tissue. J Neurosci Methods 37: 173-182.
13. Gogolla N, Galimberti I, DePaola V, Caroni P, (2006) Preparation of organotypic hippocampal slice cultures for long-term live imaging. Nat Protoc 1: 1165-1171.
14. Katayama T, Sakaguchi E, Komatsu Y, Oguma T, Uehara T, et al. (2010) Sustained activation of ERK signaling in astrocytes is critical for neuronal injury-induced monocyte chemoattractant protein-1 production in rat corticostriatal slice cultures. Eur J Neurosci 31: 1359-1367.
15. Kohl A, Dehghani F, Korf HW, Hailer NP, (2003) The bisphosphonate clodronate depletes microglial cells in excitotoxically injured organotypic hippocampal slice cultures. Exp Neurol 181: 1-11.
16. Fujimoto S, Katsuki H, Kume T, Akaike A, (2006) Thrombin-induced delayed injury involves multiple and distinct signaling pathways in the cerebral cortex and the striatum in organotypic slice cultures. Neurobiol Dis 22: 130-142.
17. Heppner FL, Skutella T, Hailer NP, Haas D, Nitsch R, (1998) Activated microglial cells migrate towards sites of excitotoxic neuronal injury inside organotypic hippocampal slice cultures. Eur J Neurosci 10: 3284-3290.
18. Petersen MA, Dailey ME, (2004) Diverse microglial motility behaviors during clearance of dead cells in hippocampal slices. Glia 46: 195-206.
19. Tanaka T, Ueno M, Yamashita T, (2009) Engulfment of axon debris by microglia requires p38 MAPK activity. J Biol Chem 284: 21626-21636.
20. Koizumi S, Shigemoto-Mogami Y, Nasu-Tada K, Shinozaki Y, Ohsawa K, et al. (2007) UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis. Nature 446: 1091-1095.
21. Fuhrmann M, Bittner T, Jung CK, Burgold S, Page RM, et al. (2010) Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease. Nat Neurosci 13: 411-413.