Synthesis and evaluation of the quorum sensing inhibitory effect of substituted triazolyldihydrofuranones

Bioorganic and Medicinal Chemistry

Volumn 20, Issue 15, 2012, Pages 4737-4743

  Brackman, Gilles ^a   Risseeuw, Martijn ^a   Celen, Shari ^a   Cos, Paul ^b   Maes, Louis ^b   Nelis, Hans J ^a   Van Calenbergh, Serge ^a   Coenye, Tom ^a  

^a GHENT UNIVERSITY   (Belgium)

^b UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Biofilm inhibition; Quorum sensing; Quorum sensing inhibition

Indexed keywords

3 (4 BENZYL 1H 1,2,3 TRIAZOL 1 YL)DIHYROFURAN 2(3H) ONE; 3 (4 BUTYL 1H 1,2,3 TRIAZOL 1 YL)DIHYROFURAN 2(3H) ONE; 3 (4 DECYL 1H 1,2,3 TRIAZOL 1 YL)DIHYROFURAN 2(3H) ONE; 3 (4 DODECYL 1H 1,2,3 TRIAZOL 1 YL)DIHYROFURAN 2(3H) ONE; 3 (4 HEPTYL 1H 1,2,3 TRIAZOL 1 YL)DIHYROFURAN 2(3H) ONE; 3 (4 HEXYL 1H 1,2,3 TRIAZOL 1 YL)DIHYROFURAN 2(3H) ONE; 3 (4 OCTYL 1H 1,2,3 TRIAZOL 1 YL)DIHYROFURAN 2(3H) ONE; 3 (4 PENTYL 1H 1,2,3 TRIAZOL 1 YL)DIHYROFURAN 2(3H) ONE; 3 (4 PHENETHYL 1H 1,2,3 TRIAZOL 1 YL)DIHYROFURAN 2(3H) ONE; 3 (4 PHENYL 1H 1,2,3 TRIAZOL 1 YL)DIHYROFURAN 2(3H) ONE; 3 AZIDODIHYDROFURAN 2(3H) ONE; FURANONE DERIVATIVE; TRIAZOLYLDIHYDROFURANONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; BINDING SITE; BIOFILM; BIOMASS; BIOSENSOR; BURKHOLDERIA CENOCEPACIA; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG DEGRADATION; DRUG EFFICACY; DRUG SELECTIVITY; DRUG SYNTHESIS; ESCHERICHIA COLI; HUMAN; HUMAN CELL; IC 50; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; POPULATION DENSITY; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; SIGNAL TRANSDUCTION;

ANTI-BACTERIAL AGENTS; BIOFILMS; BURKHOLDERIA CENOCEPACIA; DOSE-RESPONSE RELATIONSHIP, DRUG; FURANS; MOLECULAR STRUCTURE; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

BURKHOLDERIA CENOCEPACIA; PSEUDOMONAS AERUGINOSA;

EID: 84863988119     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2012.06.009     Document Type: Article

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