Genetic polymorphisms in telomere pathway genes, telomere length, and breast cancer survival

Breast Cancer Research and Treatment

Volumn 134, Issue 1, 2012, Pages 393-400

  Shen, Jing ^a   Gammon, Marilie D ^b   Terry, Mary Beth ^a   Bradshaw, Patrick T ^b   Wang, Qiao ^a   Teitelbaum, Susan L ^c   Neugut, Alfred I ^a   Santella, Regina M ^a  

^a Columbia University ^*  (United States)

^b IL   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Breast cancer; Genetic variants; Survival; Telomere length

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2;

ADULT; AGED; ALLELE; ARTICLE; BREAST CANCER; CANCER MORTALITY; CANCER SPECIFIC SURVIVAL; CANCER SURVIVAL; CAUSE OF DEATH; COHORT ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GENE; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HUMAN; MAJOR CLINICAL STUDY; PINX1 33 GENE; POPULATION RESEARCH; POT1 18 GENE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TELOMERE; TELOMERE HOMEOSTASIS; TERF 14 GENE; TERF 67 GENE; TERF2 03 GENE; UNITED STATES;

BREAST NEOPLASMS; FEMALE; GENETIC ASSOCIATION STUDIES; HUMANS; KAPLAN-MEIER ESTIMATE; NEOPLASM INVASIVENESS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROPORTIONAL HAZARDS MODELS; SEQUENCE ANALYSIS, DNA; TELOMERASE; TELOMERE; TELOMERE-BINDING PROTEINS; TELOMERIC REPEAT BINDING PROTEIN 2; TUMOR SUPPRESSOR PROTEINS;

EID: 84863985717     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-012-2058-9     Document Type: Article

References (43)

1. A Jemal R Siegel J Xu E Ward 2010 Cancer Statistics, 2010 CA Cancer J Clin 60 277 300 20610543 10.3322/caac.20073
2. PL Fitzgibbons DL Page D Weaver AD Thor DC Allred GM Clark SG Ruby F O'Malley JF Simpson JL Connolly DF Hayes SB Edge A Lichter SJ Schnitt 2000 Prognostic factors in breast cancer. College of American Pathologists Consensus Statement 1999 Arch Pathol Lab Med 124 966 978 10888772 1:STN:280: DC%2BD3czptVKrtQ%3D%3D
3. PK Morrow GN Hortobagyi 2009 Management of breast cancer in the genome era Annu Rev Med 60 153 165 19630569 10.1146/annurev.med.60.061107.145152 1:CAS:528:DC%2BD1MXitlynt7k%3D
4. SM Hsieh NA Lintell KW Hunter 2006 Germline polymorphisms are potential metastasis risk and prognosis markers in breast cancer Breast Dis 26 157 162 17473374 1:CAS:528:DC%2BD2sXksVCjt7Y%3D
5. KW Hunter 2004 Host genetics and tumour metastasis Br J Cancer 90 752 755 14970848 10.1038/sj.bjc.6601590 1:CAS:528:DC%2BD2cXht12itbk%3D
6. NB Peterson A Beeghly-Fadiel YT Gao J Long Q Cai XO Shu W Zheng 2009 Polymorphisms in tissue inhibitors of metalloproteinases-2 and -3 and breast cancer susceptibility and survival Int J Cancer 125 844 850 19431211 10.1002/ijc.24405 1:CAS:528:DC%2BD1MXnsFeltL4%3D
7. M Udler AT Maia A Cebrian C Brown D Greenberg M Shah C Caldas A Dunning D Easton B Ponder P Pharoah 2007 Common germline genetic variation in antioxidant defense genes and survival after diagnosis of breast cancer J Clin Oncol 25 3015 3023 17634480 10.1200/JCO.2006.10.0099 1:CAS:528:DC%2BD2sXptlGrsLk%3D
8. MS Udler EM Azzato CS Healey S Ahmed KA Pooley D Greenberg M Shah AE Teschendorff C Caldas AM Dunning EA Ostrander NE Caporaso D Easton PD Pharoah 2009 Common germline polymorphisms in COMT, CYP19A1, ESR1, PGR, SULT1E1 and STS and survival after a diagnosis of breast cancer Int J Cancer 125 2687 2696 19551860 10.1002/ijc.24678 1:CAS:528:DC%2BD1MXht1WmsLbO
9. A Gerger W Renner T Langsenlehner G Hofmann G Knechtel J Szkandera H Samonigg P Krippl U Langsenlehner 2010 Association of interleukin-10 gene variation with breast cancer prognosis Breast Cancer Res Treat 119 701 705 19437115 10.1007/s10549-009-0417-y 1:CAS:528:DC%2BC3cXlslWkuw%3D%3D
10. C Grimm E Kantelhardt G Heinze S Polterauer R Zeillinger H Kolbl A Reinthaller L Hefler 2009 The prognostic value of four interleukin-1 gene polymorphisms in Caucasian women with breast cancer: a multicenter study BMC Cancer 9 78 19267917 10.1186/1471-2407-9-78
11. Reis-Filho JS, Weigelt B, Fumagalli D, Sotiriou C (2010) Molecular profiling: moving away from tumor philately. Sci Transl Med 2:47ps43
12. MT Weigel M Dowsett 2010 Current and emerging biomarkers in breast cancer: prognosis and prediction Endocr Relat Cancer 17 R245 R262 20647302 10.1677/ERC-10-0136 1:CAS:528:DC%2BC3MXislyms7w%3D
13. EH Blackburn 1991 Structure and function of telomeres Nature 350 569 573 1708110 10.1038/350569a0 1:CAS:528:DyaK3MXisVWnsLg%3D
14. G De Boeck RG Forsyth M Praet PC Hogendoorn 2009 Telomere-associated proteins: cross-talk between telomere maintenance and telomere-lengthening mechanisms J Pathol 217 327 344 19142887 10.1002/path.2500
15. M Salhab WG Jiang RF Newbold K Mokbel 2007 The expression of gene transcripts of telomere-associated genes in human breast cancer: correlation with clinico-pathological parameters and clinical outcome Breast Cancer Res Treat 109 35 46 17616810 10.1007/s10549-007-9622-8
16. U Svenson K Nordfjall B Stegmayr J Manjer P Nilsson B Tavelin R Henriksson P Lenner G Roos 2008 Breast cancer survival is associated with telomere length in peripheral blood cells Cancer Res 68 3618 3623 18483243 10.1158/0008-5472.CAN-07-6497 1:CAS:528:DC%2BD1cXlvVOit7Y%3D
17. V Varadi A Brendle A Brandt R Johansson K Enquist R Henriksson U Svenson B Tavelin G Roos K Hemminki P Lenner A Forsti 2009 Polymorphisms in telomere-associated genes, breast cancer susceptibility and prognosis Eur J Cancer 45 3008 3016 19766477 10.1016/j.ejca.2009.08.012 1:CAS:528: DC%2BD1MXhtlyjsbbI
18. M Bisoffi CM Heaphy JK Griffith 2006 Telomeres: prognostic markers for solid tumors Int J Cancer 119 2255 2260 16858685 10.1002/ijc.22120 1:CAS:528:DC%2BD28XhtVylsL3M
19. U Svenson G Roos 2009 Telomere length as a biological marker in malignancy Biochim Biophys Acta 1792 317 323 19419696 10.1016/j.bbadis.2009.01. 017 1:CAS:528:DC%2BD1MXksVaqsb8%3D
20. X Zhou AK Meeker KH Makambi O Kosti BV Kallakury MK Sidawy CA Loffredo YL Zheng 2012 Telomere length variation in normal epithelial cells adjacent to tumor: potential biomarker for breast cancer local recurrence Carcinogenesis 33 113 118 22072619 10.1093/carcin/bgr248
21. RJ Cleveland SM Eng PE Abrahamson JA Britton SL Teitelbaum AI Neugut MD Gammon 2007 Weight gain prior to diagnosis and survival from breast cancer Cancer Epidemiol Biomarkers Prev 16 1803 1811 17855698 10.1158/1055-9965.EPI-06- 0889
22. MD Gammon AI Neugut RM Santella SL Teitelbaum JA Britton MB Terry SM Eng MS Wolff SD Stellman GC Kabat B Levin HL Bradlow M Hatch J Beyea D Camann M Trent RT Senie G Garbowski C Maffeo P Montalvan GS Berkowitz M Kemeny C Citron F Schnabel A Schuss S Hajdu V Vinceguerra GW Collman G Obrams 2002 The Long Island Breast Cancer Study Project: description of a multi-institutional collaboration to indentify environmental risk factors for breast cancer Breast Cancer Res Treat 74 235 254 12206514 10.1023/A:1016387020854 1:CAS:528:DC%2BD38Xltlems78%3D
23. X Xu MD Gammon Y Zhang TH Bestor SH Zeisel JG Wetmur S Wallenstein PT Bradshaw G Garbowski SL Teitelbaum AI Neugut RM Santella J Chen 2010 BRCA1 promoter methylation is associated with increased mortality among women with breast cancer Breast Cancer Res Treat 121 685 692 19921426 10.1007/s10549-009- 0628-2 1:CAS:528:DC%2BC3cXmtVyrsbg%3D
24. MD Gammon RM Santella AI Neugut SM Eng SL Teitelbaum A Paykin B Levin MB Terry TL Young LW Wang Q Wang JA Britton MS Wolff SD Stellman M Hatch GC Kabat R Senie G Garbowski C Maffeo P Montalvan GS Berkowitz M Kemeny M Citron F Schnabel A Schuss S Hajdu V Vinceguerra 2002 Environmental toxins and breast cancer on Long Island. I. Polycyclic aromatic hydrocarbon DNA adducts Cancer Epidemiol Biomarkers Prev 11 677 685 12163319 1:CAS:528:DC%2BD38XmvVaqsrc%3D
25. T Andrew A Aviv M Falchi GL Surdulescu JP Gardner X Lu M Kimura BS Kato AM Valdes TD Spector 2006 Mapping genetic loci that determine leukocyte telomere length in a large sample of unselected female sibling pairs Am J Hum Genet 78 480 486 16400618 10.1086/500052 1:CAS:528:DC%2BD28XitVWqtLg%3D
26. MA Blasco 2005 Telomeres and human disease: ageing, cancer and beyond Nat Rev Genet 6 611 622 16136653 10.1038/nrg1656 1:CAS:528:DC%2BD2MXntFeqtbw%3D
27. F Rodier SH Kim T Nijjar P Yaswen J Campisi 2005 Cancer and aging: the importance of telomeres in genome maintenance Int J Biochem Cell Biol 37 977 990 15743672 10.1016/j.biocel.2004.10.012 1:CAS:528:DC%2BD2MXhvVGjsL8%3D
28. SA Savage BJ Stewart JS Liao LJ Helman SJ Chanock 2005 Telomere stability genes are not mutated in osteosarcoma cell lines Cancer Genet Cytogenet 160 79 81 15949576 10.1016/j.cancergencyto.2004.12.004 1:CAS:528:DC%2BD2MXltFaqsLo%3D
29. J Shen MD Gammon HC Wu MB Terry Q Wang P Bradshaw SL Teitelbaum AI Neugut RM Santella 2010 Multiple genetic variants in telomere pathway genes and breast cancer risk Cancer Epidemiol Biomark Prev 19 219 228 10.1158/1055-9965.EPI-09- 0771 1:CAS:528:DC%2BC3cXhvFensg%3D%3D
30. RM Cawthon 2002 Telomere measurement by quantitative PCR Nucleic Acids Res 30 e47 12000852 10.1093/nar/30.10.e47
31. J Shen MD Gammon MB Terry Q Wang P Bradshaw SL Teitelbaum AI Neugut RM Santella 2009 Telomere length, oxidative damage, antioxidants and breast cancer risk Int J Cancer 124 1637 1643 19089916 10.1002/ijc.24105 1:CAS:528: DC%2BD1MXivVars78%3D
32. DG Cox F Canzian 2001 Genotype transposer: automated genotype manipulation for linkage disequilibrium analysis Bioinformatics 17 738 739 11524375 10.1093/bioinformatics/17.8.738 1:CAS:528:DC%2BD3MXntFKjsbs%3D
33. EL Kaplan P Meier 1958 Nonparametric estimation from incomplete observations J Am Stat Assoc 53 457 481
34. CA Fordyce CM Heaphy M Bisoffi JL Wyaco NE Joste A Mangalik KB Baumgartner RN Baumgartner WC Hunt JK Griffith 2006 Telomere content correlates with stage and prognosis in breast cancer Breast Cancer Res Treat 99 193 202 16752076 10.1007/s10549-006-9204-1
35. RM Cawthon 2009 Telomere length measurement by a novel monochrome multiplex quantitative PCR method Nucleic Acids Res 37 e21 19129229 10.1093/nar/gkn1027
36. Liu HQ, An JZ, Liu J, Yang YF, Zhang HX, Zhao BY, Li JB, Yang HS, Chen ZN, Xing JL (2012) Leukocyte telomere length predicts overall survival in hepatocellular carcinoma treated with transarterial chemoembolization. Carcinogenesis. doi: 10.1093/carcin/bgs098
37. E Muraro D Martorelli E Turchet G Miolo S Scalone E Comaro R Talamini K Mastorci D Lombardi T Perin A Carbone A Veronesi D Crivellari R Dolcetti 2011 A different immunologic profile characterizes patients with HER-2-overexpressing and HER-2-negative locally advanced breast cancer: implications for immune-based therapies Breast Cancer Res 13 R117 22112244 10.1186/bcr3060 1:CAS:528:DC%2BC38XjslOlsL0%3D
38. NP Weng 2008 Telomere and adaptive immunity Mech Ageing Dev 129 60 66 18199471 10.1016/j.mad.2007.11.005 1:CAS:528:DC%2BD1cXhslygt7s%3D
39. RJ Hodes KS Hathcock NP Weng 2002 Telomeres in T and B cells Nat Rev Immunol 2 699 706 12209138 10.1038/nri890 1:CAS:528:DC%2BD38Xmslant7k%3D
40. CP Hsu NY Hsu LW Lee JL Ko 2006 Ets2 binding site single nucleotide polymorphism at the hTERT gene promoter-effect on telomerase expression and telomere length maintenance in non-small cell lung cancer Eur J Cancer 42 1466 1474 16737810 10.1016/j.ejca.2006.02.014 1:CAS:528:DC%2BD28XlvF2jsLY%3D
41. T Kondo N Oue K Yoshida Y Mitani K Naka H Nakayama W Yasui 2004 Expression of POT1 is associated with tumor stage and telomere length in gastric carcinoma Cancer Res 64 523 529 14744765 10.1158/0008-5472.CAN-03-1196 1:CAS:528:DC%2BD2cXmsVWrtA%3D%3D
42. A Elkak R Mokbel C Wilson WG Jiang RF Newbold K Mokbel 2006 hTERT mRNA expression is associated with a poor clinical outcome in human breast cancer Anticancer Res 26 4901 4904 17214359 1:CAS:528:DC%2BD2sXps1Srtw%3D%3D
43. J Lin R Jin B Zhang PX Yang H Chen YX Bai Y Xie C Huang J Huang 2007 Characterization of a novel effect of hPinX1 on hTERT nucleolar localization Biochem Biophys Res Commun 353 946 952 17198684 10.1016/j.bbrc.2006.12.123 1:CAS:528:DC%2BD2sXmtVaqsg%3D%3D