The prognostic value of four interleukin-1 gene polymorphisms in caucasian women with breast cancer - A multicenter study

BMC Cancer

Volumn 9, Issue , 2009, Pages

  Grimm, Christoph ^a   Kantelhardt, Eva ^b   Heinze, Georg ^c   Polterauer, Stephan ^a   Zeillinger, Robert ^a   Kölbl, Heinz ^d   Reinthaller, Alexander ^a   Hefler, Lukas ^a  

^a UNIV KLIN FÜR FRAUENHEILKUNDE   (Austria)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

^d JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1; IL1RN PROTEIN, HUMAN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT;

ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER MORTALITY; CANCER PATIENT; CANCER RISK; CANCER SURVIVAL; CAUCASIAN; CONFIDENCE INTERVAL; CONTROLLED STUDY; DISEASE FREE SURVIVAL; DNA POLYMORPHISM; FEMALE; FOLLOW UP; GENOTYPE; HAPLOTYPE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MULTIVARIATE ANALYSIS; MUTANT; OVERALL SURVIVAL; PROGNOSIS; PROTEIN FAMILY; RISK ASSESSMENT; UNIVARIATE ANALYSIS; ALLELE; BREAST TUMOR; ETHNOLOGY; GENETIC POLYMORPHISM; GENETICS; MIDDLE AGED;

ALLELES; BREAST NEOPLASMS; DISEASE-FREE SURVIVAL; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1; MIDDLE AGED; POLYMORPHISM, GENETIC;

EID: 63049103423     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-9-78     Document Type: Article

References (32)

1. Ricote M Garcia-Tunon I Bethencourt FR Fraile B Paniagua R Royuela M Interleukin-1 (IL-1alpha and IL-1beta) and its receptors (IL-1RI, IL-1RII, and IL-1Ra) in prostate carcinoma Cancer 2004, 100:1388-1396. 10.1002/cncr.20142 15042672
2. Dinarello CA Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist Int Rev Immunol 1998, 16:457-499. 10.3109/ 08830189809043005 9646173
3. Sauer J Renner U Hopfner U Lange M Müller A Strasburger CJ Pagotto U Arzt E Stalla GK Interleukin-1 beta enhances interleukin-1 receptor antagonist content in human somatotroph adenoma cell cultures J Clin Endocrinol 1998, 83:2429-2434. 10.1210/jc.83.7.2429
4. Cooke MM McCarthy GM Sallis JD Morgan MP Phosphocitrate inhibits calcium hydroxyapatite induced mitogenesis and upregulation of matrix metalloproteinase-1, interleukin-1beta and cyclooxygenase-2 mRNA in human breast cancer cell lines Breast Cancer Res Treat 2003, 79:253-263. 10.1023/A:1023908307108 12825860
5. Miller LJ Kurtzman SH Anderson K Wang Y Stankus M Renna M Lindquist R Barrows G Kreutzer DL Interleukin-1 family expression in human breast cancer: Interleukin-1 receptor antagonist Cancer Invest 2000, 18:293-302. 10.3109/07357900009012171 10808364
6. Wolf JS Chen Z Dong G Sunwoo JB Bancroft CC Capo DE Yeh NT Mukaida N Van Waes C IL (Interleukin)-1alpha promotes nuclear factor-kappaB and AP-1-induced IL-8 expression, cell survival, and proliferation in head and neck squamous cell carcinomas Clin Cancer Res 2001, 7:1812-1820. 11410524
7. Kimura H Inukai Y Takii T Furutani Y Shibata Y Hayashi H Sakurada S Okamoto T Inoue J Oomoto Y Onozaki K Molecular analysis of constitutive IL-1alpha gene expression in human melanoma cells: Autocrine stimulation through NF-KB activation by endogenous IL-1alpha Cytokine 1998, 10:873-879. 10.1006/cyto.1998.0369
8. Nozaki S Sledge GW Jr Nakshatri H Cancer cell-derived interleukin 1 alpha contributes to autocrine and paracrine induction of prometastatic genes in breast cancer Biochem Biophys Res Commun 2000, 275:60-62. 10.1006/bbrc.2000.3241 10944441
9. Singer CF Hudelist G Gschwantler-Kaulich D Fink-Retter A Mueller R Walter I Czerwenka K Kubista E Interleukin-1alpha protein secretion in breast cancer is associated with poor differentiation and estrogen receptor alpha negativity Int J Gynecol Cancer 2006, 16:556-559. 10.1111/ j.1525-1438.2006.00695.x 17010072
10. Singer CF Kronsteiner N Hudelist G Marton E Walter I Kubista M Czerwenka K Schreiber M Seifert M Kubista E Interleukin 1 system and sex steroid receptor expression in human breast cancer: Interleukin 1alpha protein secretion is correlated with malignant phenotype Clin Cancer Res 2003, 9:4877-4883. 14581361
11. Dinarello CA Biologic basis for interleukin-1 in disease Blood 1996, 87:2095-2147. 8630372
12. Pociot F Molvig J Wogensen L Worsaae H Nerup J TaqI polymorphism in the human interleukin-1 beta (IL-1 beta) gene correlates with IL-1 beta secretion in vitro Eur J Clin Invest 1992, 22:396-402. 10.1111/ j.1365-2362.1992.tb01480.x 1353022
13. di Giovine FS Takhsh E Blakemore Al Duff GW Single base polymorphism at -511 in the human interleukin-1 beta gene (IL1 beta) Hum Mol Genet 1992, 1:450. 10.1093/hmg/1.6.450 1301918
14. Hulkkonen J Laippala P Hurme M A rare allele combination of the interleukin-1 gene complex is associated with high interleukin-1 beta plasma levels in healthy individuals Eur Cytokine Netw 2000, 11:251-255. 10903804
15. Danis VA Millington M Hyland VJ Grennan D Cytokine production by normal human monocytes: Inter-subject variation and relationship to an IL-1 receptor antagonist (IL-1Ra) gene polymorphism Clin Exp Immunol 1995, 99:303-310. 1534297 7851026
16. Dewberry R Holden H Crossman D Francis S Interleukin-1 receptor antagonist expression in human endothelial cells and atherosclerosis Arterioscler Thromb Vasc Biol 2000, 20:2394-2400. 11073843
17. Sehouli J Mustea A Koensgen D Lichtenegger W Interleukin-1 receptor antagonist gene polymorphism in epithelial ovarian cancer Cancer Epidemiol Biomarkers Prev 2003, 12:1205-1208. 14652282
18. Palli D Saieva C Luzzi I Masala G Topa S Sera F Gemma S Zanna I D'Errico M Zini E Guidotti S Valeri A Fabbrucci P Moretti R Testai E del Giudice G Ottini L Matullo G Dogliotti E Gomez-Miguel MJ Interleukin-1 gene polymorphisms and gastric cancer risk in a high-risk Italian population Am J Gastroenterol 2005, 100:1941-1948. 10.1111/j.1572-0241.2005.50084.x 16128937
19. Lind H Zienolddiny S Ryberg D Skaug V Phillips DH Haugen A Interleukin 1 receptor antagonist gene polymorphism and risk of lung cancer: A possible interaction with polymorphisms in the interleukin 1 beta gene Lung Cancer 2005, 50:285-290. 10.1016/j.lungcan.2005.07.003 16126303
20. Lindmark F Zheng SL Wiklund F Bälter KA Sun J Chang B Hedelin M Clark J Johansson JE Meyers DA Adami HO Isaacs W Grönberg H Xu J Interleukin-1 receptor antagonist haplotype associated with prostate cancer risk Br J Cancer 2005, 93:493-497. 10.1038/sj.bjc.6602729 16106254
21. Lee KM Park SK Hamajima N Tajima K Choi JY Noh DY Ahn SH Yoo KY Hirvonen A Kang D Genetic polymorphisms of interleukin-1 beta (IL-1B) and IL-1 receptor antagonist (IL-1RN) and breast cancer risk in Korean women Breast Cancer Res Treat 2006, 96:197-202. 10.1007/s10549-005-9079-6 16319982
22. Liu J Zhai X Jin G Hu Z Wang S Wang X Qin J Gao J Ma H Wang X Wei Q Shen H Functional variants in the promoter of interleukin-1beta are associated with an increased risk of breast cancer: A case-control analysis in a Chinese population Int J Cancer 2006, 118:2554-2558. 10.1002/ijc.21652 16358261
23. Snoussi K Mahfoudh W Bouaouina N Ahmed SB Helal AN Chouchane L Genetic variation in IL-8 associated with increased risk and poor prognosis of breast carcinoma Hum Immunol 2006, 67:13-21. 10.1016/ j.humimm.2006.03.018 16698420
24. Smith KC Bateman AC Fussell HM Howell WM Cytokine gene polymorphisms and breast cancer susceptibility and prognosis Eur J Immunogenet 2004, 31:167-173. 10.1111/j.1365-2370.2004.00462.x 15265021
25. Iacopetta B Grieu F Joseph D The -174 G/C gene polymorphism in interleukin-6 is associated with an aggressive breast cancer phenotype Br J Cancer 2004, 90:419-422. 10.1038/sj.bjc.6601545 14735187
26. Snoussi K Strosberg AD Bouaouina N Ben Ahmed S Chouchane L Genetic variation in pro-inflammatory cytokines (interleukin-1beta, interleukin-1alpha and interleukin-6) associated with the aggressive forms, survival, and relapse prediction of breast carcinoma Eur Cytokine Netw 2005, 16:253-260. 16464738
27. Grimm C Berger I Tomovski C Zeillinger R Concin N Leodolter S Koelbl H Tempfer CB Hefler LA A polymorphism of the interleukin-1 receptor antagonist plays a prominent role within the interleukin-1 gene cluster in vulvar carcinogenesis Gynecol Oncol 2004, 92:936-940. 10.1016/ j.ygyno.2003.11.039 14984963
28. Hefler LA Grimm C Lantzsch T Lampe D Leodolter S Koelbl H Heinze G Reinthaller A Tong-Cacsire D Tempfer C Zeillinger R Interleukin-1 and interleukin-6 gene polymorphisms and the risk of breast cancer in caucasian women Clin Cancer Res 2005, 11:5718-5721. 10.1158/ 1078-0432.CCR-05-0001 16115908
29. Tarlow JK Blakemore AI Lennard A Solari R Hughes HN Steinkasserer A Duff GW Polymorphism in human IL-1 receptor antagonist gene intron 2 is caused by variable numbers of an 86-bp tandem repeat Hum Genet 1993, 91:403-404. 10.1007/BF00217368 8500797
30. Cvetkovic RS Keating G Anakinra BioDrugs 2002, 16:303-311. 10.2165/ 00063030-200216040-00005 12196041
31. Bar D Apte RN Voronov E Dinarello CA Cohen S A continuous delivery system of IL-1 receptor antagonist reduces angiogenesis and inhibits tumor development FASEB J 2004, 18:161-163. 14597552
32. Weinreich DM Elaraj DM Puhlmann M Hewitt SM Carroll NM Feldman ED Turner EM Spiess PJ Alexander HR Effect of interleukin 1 receptor antagonist gene transduction on human melanoma xenografts in nude mice Cancer Res 2003, 63:5957-5961. 14522922