Adipose-derived stem cells combined with a demineralized cancellous bone substrate for bone regeneration

Tissue Engineering - Part A

Volumn 18, Issue 13-14, 2012, Pages 1313-1321

  Shi, Yaling ^a   Niedzinski, Jerry R ^b   Samaniego, Adrian ^a   Bogdansky, Simon ^a   Atkinson, Brent L ^a  

^a AlloSource   (United States)

^b LABS Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE; CARTILAGE; FLOW CYTOMETRY; FLOWCHARTING; PHOSPHATASES; SCAFFOLDS (BIOLOGY); STEM CELLS; TISSUE;

ADIPOGENESIS; ADIPOSE DERIVED STEM CELLS; ADIPOSE TISSUE; ALIZARIN RED; ALKALINE PHOSPHATASE; BODY MASS INDEX; BONE ALLOGRAFTS; BONE FORMATION; BONE GRAFT; BONE REGENERATION; BONE SCAFFOLDS; CANCELLOUS BONE; CELL NUMBER; CHONDROGENESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; EX-VIVO; FLOW-CYTOMETER; IN-VITRO; IN-VIVO; KEY ELEMENTS; MESENCHYMAL STEM CELL; OSTEOCONDUCTIVE; OSTEOGENESIS; OSTEOGENIC; OSTEOGENIC ACTIVITY; VIABLE CELLS;

CELL CULTURE;

BONE MORPHOGENETIC PROTEIN; MINERAL;

ADIPOSE TISSUE; AGED; ALLOGRAFT; ARTICLE; BODY MASS; BONE; BONE DEVELOPMENT; BONE REGENERATION; CELL ADHESION; CELL COUNT; CELL DIFFERENTIATION; CELL LINEAGE; CYTOLOGY; FEMALE; HISTOLOGY; HUMAN; IMMUNOPHENOTYPING; MALE; MESENCHYMAL STROMA CELL; METABOLISM; MIDDLE AGED; PHYSIOLOGY; STAINING; STROMA CELL; ULTRASTRUCTURE;

ADIPOSE TISSUE; AGED; ALLOGRAFTS; BODY MASS INDEX; BONE AND BONES; BONE DEMINERALIZATION TECHNIQUE; BONE MORPHOGENETIC PROTEINS; BONE REGENERATION; CELL ADHESION; CELL COUNT; CELL DIFFERENTIATION; CELL LINEAGE; FEMALE; HUMANS; IMMUNOPHENOTYPING; MALE; MESENCHYMAL STROMAL CELLS; MIDDLE AGED; MINERALS; OSTEOGENESIS; STAINING AND LABELING; STROMAL CELLS;

EID: 84863970306     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2011.0357     Document Type: Article

References (65)

1. Cui, L., et al. Repair of cranial bone defects with adipose derived stem cells and coral scaffold in a canine model. Biomaterials 28, 5477, 2007.
2. De Girolamo, L., et al. Human adipose-derived stem cells as future tools in tissue regeneration: osteogenic differentiation and cell-scaffold interaction. Int J Artif Organs 31, 467, 2008.
3. Liu, G., et al. Evaluation of partially demineralized osteoporotic cancellous bone matrix combined with human bone marrow stromal cells for tissue engineering: an in vitro and in vivo study. Calcif Tissue Int 83, 176, 2008.
4. Lopez, M.J., et al. Acceleration of spinal fusion using syngeneic and allogeneic adult adipose derived stem cells in a rat model. J Orthop Res 27, 366, 2009.
5. Supronowicz, P., et al. Human adipose-derived side population stem cells cultured on demineralized bone matrix for bone tissue engineering. Tissue Eng Part A 17, 789, 2011.
6. Yoon, E., et al. In vivo osteogenic potential of human adipose-derived stem cells/poly lactide-co-glycolic acid constructs for bone regeneration in a rat critical-sized calvarial defect model. Tissue Eng 13, 619, 2007.
7. Rosenbaum, A.J., Grande, D.A., and Dines, J.S. The use of mesenchymal stem cells in tissue engineering: a global assessment. Organogenesis 4, 23, 2008.
8. Gimble, J., and Guilak, F. Adipose-derived adult stem cells: isolation, characterization, and differentiation potential. Cytotherapy 5, 362, 2003.
9. Gimble, J.M., and Guilak, F. Differentiation potential of adipose derived adult stem (ADAS) cells. Curr Top Dev Biol 58, 137, 2003.
10. Strem, B.M., et al. Multipotential differentiation of adipose tissue-derived stem cells. Keio J Med 54, 132, 2005.
11. Yoshimura, H., et al. Comparison of rat mesenchymal stem cells derived from bone marrow, synovium, periosteum, adipose tissue, and muscle. Cell Tissue Res 327, 449, 2007.
12. Le Blanc, K., et al. HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells. Exp Hematol 31, 890, 2003.
13. Rasmusson, I., et al. Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells. Transplantation 76, 1208, 2003.
14. Di Bella, C., Farlie, P., and Penington, A.J. Bone regeneration in a rabbit critical-sized skull defect using autologous adipose-derived cells. Tissue Eng Part A 14, 483, 2008.
15. Grewal, N.S., et al. BMP-2 does not influence the osteogenic fate of human adipose-derived stem cells. Plast Reconstr Surg 123 2 Suppl, 158S, 2009.
16. Li, H., et al. Bone regeneration by implantation of adiposederived stromal cells expressing BMP-2. Biochem Biophys Res Commun 356, 836, 2007.
17. Rada, T., Reis, R.L., and Gomes, M.E. Adipose tissuederived stem cells and their application in bone and cartilage tissue engineering. Tissue Eng Part B Rev 15, 113, 2009.
18. Tapp, H., et al. Adipose-derived stem cells: characterization and current application in orthopaedic tissue repair. Exp Biol Med 234, 1, 2009.
19. Butt, O.I., et al. Stimulation of peri-implant vascularization with bone marrow-derived progenitor cells: monitoring by in vivo EPR oximetry. Tissue Eng 13, 2053, 2007.
20. Rigotti, G., et al. Clinical treatment of radiotherapy tissue damage by lipoaspirate transplant: a healing process mediated by adipose-derived adult stem cells. Plast Reconstr Surg 119, 1409, 2007; discussion 1423.
21. Hou, R., et al. Comparative study between coral-mesenchymal stem cells-rhBMP-2 composite and auto-bone-graft in rabbit critical-sized cranial defect model. J Biomed Mater Res A 80, 85, 2007.
22. Gamradt, S.C., and Lieberman, J.R. Bone graft for revision hip arthroplasty: biology and future applications. Clin Orthop Relat Res 183, 2003.
23. Honsawek, S., Dhitiseith, D., and Phupong, V. Effects of demineralized bone matrix on proliferation and osteogenic differentiation of mesenchymal stem cells from human umbilical cord. J Med Assoc Thai 89 Suppl 3, S189, 2006.
24. Kasten, P., et al. [Induction of bone tissue on different matrices: an in vitro and a in vivo pilot study in the SCID mouse]. Z Orthop Ihre Grenzgeb 142, 467, 2004.
25. Kasten, P., et al. Ectopic bone formation associated with mesenchymal stem cells in a resorbable calcium deficient hydroxyapatite carrier. Biomaterials 26, 5879, 2005.
26. Liu, G., et al. Tissue-engineered bone formation with cryopreserved human bone marrow mesenchymal stem cells. Cryobiology 56, 209, 2008.
27. Liu, G., et al. Evaluation of the viability and osteogenic differentiation of cryopreserved human adipose-derived stem cells. Cryobiology 57, 18, 2008.
28. Qian, Y., Shen, Z., and Zhang, Z. [Reconstruction of bone using tissue engineering and nanoscale technology]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 20, 560, 2006.
29. Reddi, A.H. Morphogenesis and tissue engineering of bone and cartilage: inductive signals, stem cells, and biomimetic biomaterials. Tissue Eng 6, 351, 2000.
30. Tsiridis, E., et al. In vitro and in vivo optimization of impaction allografting by demineralization and addition of rh-OP-1. J Orthop Res 25, 1425, 2007.
31. Xie, H., et al. The performance of a bone-derived scaffold material in the repair of critical bone defects in a rhesus monkey model. Biomaterials 28, 3314, 2007.
32. Blum, B., et al. Measurement of BMP and Other Growth Factors in DBM. Orthop Today 1, 2011.
33. Mauney, J.R., et al. In vitro and in vivo evaluation of differentially demineralized cancellous bone scaffolds combined with human bone marrow stromal cells for tissue engineering. Biomaterials 26, 3173, 2005.
34. Tsiridis, E., et al. In vitro proliferation and differentiation of human mesenchymal stem cells on hydroxyapatite versus human demineralised bone matrix with and without osteogenic protein-1. Expert Opin Biol Ther 9, 9, 2009.
35. Seebach, C., et al. Comparison of six bone-graft substitutes regarding to cell seeding efficiency, metabolism and growth behaviour of human mesenchymal stem cells (MSC) in vitro. Injury 41, 731, 2010.
36. Stiehler, M., et al. Cancellous bone allograft seeded with human mesenchymal stromal cells: a potential good manufacturing practice-grade tool for the regeneration of bone defects. Cytotherapy 12, 658, 2010.
37. Sheyn, D., et al., Genetically modified mesenchymal stem cells induce mechanically stable posterior spine fusion. Tissue Eng Part A 16, 3679, 2010.
38. Huang, Z., et al. Modulating osteogenesis of mesenchymal stem cells by modifying growth factor availability. Cytokine 51, 305, 2010.
39. Sekiya, K., et al. Enhancement of osteogenesis by concanavalin A in human bone marrow mesenchymal stem cell cultures. Int J Artif Organs 31, 708, 2008.
40. Maegawa, N., et al. Enhancement of osteoblastic differentiation of mesenchymal stromal cells cultured by selective combination of bone morphogenetic protein-2 (BMP-2) and fibroblast growth factor-2 (FGF-2). J Tissue Eng Regen Med 1, 306, 2007.
41. Moutsatsos, I.K., et al. Exogenously regulated stem cell-mediated gene therapy for bone regeneration. Mol Ther 3, 449, 2001.
42. Hosokawa, R., et al. Direct bone induction in the subperiosteal space of rat calvaria with demineralized bone allografts. J Oral Implantol 25, 30, 1999.
43. Dominici, M., et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy, 8, 315, 2006.
44. Yoshimura, K., et al. Characterization of freshly isolated and cultured cells derived from the fatty and fluid portions of liposuction aspirates. J Cell Physiol 208, 64, 2006.
45. Zheng, B., et al. Mouse adipose-derived stem cells undergo multilineage differentiation in vitro but primarily osteogenic and chondrogenic differentiation in vivo. Tissue Eng 12, 1891, 2006.
46. Zhu, M., et al. [Cell biological study of adipose-derived stem cells]. Nan Fang Yi Ke Da Xue Xue Bao 27, 518, 2007.
47. Zuk, P.A., et al. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng 7, 211, 2001.
48. Aust, L., et al. Yield of human adipose-derived adult stem cells from liposuction aspirates. Cytotherapy 6, 7, 2004.
49. Korn, B.S., Kikkawa, D.O., and Hicok, K.C. Identification and characterization of adult stem cells from human orbital adipose tissue. Ophthal Plast Reconstr Surg 25, 27, 2009.
50. McIntosh, K., et al. The immunogenicity of human adiposederived cells: temporal changes in vitro. Stem Cells 24, 1246, 2006.
51. Mitchell, J.B., et al. Immunophenotype of human adiposederived cells: temporal changes in stromal-associated and stem cell-associated markers. Stem cells 24, 376, 2006.
52. Fleming, J.E., Jr., Cornell, C.N., and Muschler, G.F. Bone cells and matrices in orthopedic tissue engineering. Orthop Clin North Am 31, 357, 2000.
53. Ludwig, S.C., and Boden, S.D. Osteoinductive bone graft substitutes for spinal fusion: a basic science summary. Orthop Clin North Am 30, 635, 1999.
54. Muschler, G.F., et al. Selective retention of bone marrowderived cells to enhance spinal fusion. Clin Orthop Relat Res 242, 2005.
55. Muschler, G.F., Midura, R.J., and Nakamoto, C. Practical Modeling Concepts for Connective Tissue Stem Cell and Progenitor Compartment Kinetics. J Biomed Biotechnol 2003, 170, 2003.
56. Muschler, G.F., et al. Age-and gender-related changes in the cellularity of human bone marrow and the prevalence of osteoblastic progenitors. J Orthop Res 19, 117, 2001.
57. Hernigou, P., et al. Percutaneous autologous bone-marrow grafting for nonunions. Surgical technique. J Bone Joint Surg Am 88 Suppl 1 Pt 2, 322, 2006.
58. Hernigou, P., et al. Percutaneous autologous bone-marrow grafting for nonunions. Influence of the number and concentration of progenitor cells. J Bone Joint Surg Am 87, 1430, 2005.
59. Glowacki, J., Zhou, S., and Mizuno, S. Mechanisms of osteoinduction/ chondroinduction by demineralized bone. J Craniofac Surg 20 Suppl 1, 634, 2009.
60. Peterson, B., et al. Osteoinductivity of commercially available demineralized bone matrix. Preparations in a spine fusion model. J Bone Joint Surg Am 86-A, 2243, 2004.
61. Wildemann, B., et al. Quantification of various growth factors in different demineralized bone matrix preparations. J Biomed Mater Res A 81, 437, 2007.
62. Bruder, S.P., and Fox, B.S. Tissue engineering of bone. Cell based strategies. Clin Orthop Relat Res 367 Suppl, S68, 1999.
63. Wang, J., and Glimcher, M.J. Characterization of matrixinduced osteogenesis in rat calvarial bone defects: II. Origins of bone-forming cells. Calcif Tissue Int 65, 486, 1999.
64. Wang, J., and Glimcher, M.J. Characterization of matrixinduced osteogenesis in rat calvarial bone defects: I. Differences in the cellular response to demineralized bone matrix implanted in calvarial defects and in subcutaneous sites. Calcif Tissue Int 65, 156, 1999.
65. Wang, J., et al. Characterization of demineralized bone matrix-induced osteogenesis in rat calvarial bone defects: III. Gene and protein expression. Calcif Tissue Int 67, 314, 2000.