Development of a bioanalytical method for quantification of a 15-mer oligonucleotide at sub-ng/ml concentrations using LC-MS/MS

Bioanalysis

Volumn 4, Issue 12, 2012, Pages 1457-1469

  Hemsley, Martyn ^a   Ewles, Matthew ^a   Lee, Goodwin ^a  

^a Department of Genetic and Molecular Toxicology   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGONUCLEOTIDE;

ACCURACY; ANALYTIC METHOD; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DETERMINATION; HIGH THROUGHPUT SCREENING; HUMAN; HYDROPHILIC INTERACTION CHROMATOGRAPHY; ION PAIR EXTRACTION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; VALIDATION PROCESS;

CHROMATOGRAPHY, REVERSE-PHASE; HUMANS; LIMIT OF DETECTION; OLIGONUCLEOTIDES; REFERENCE STANDARDS; RNA, SMALL INTERFERING; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

EID: 84863956914     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.12.117     Document Type: Article

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