Transgenic Anopheles stephensi coexpressing single-chain antibodies resist Plasmodium falciparum development

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 28, 2012, Pages

  Isaacs, Alison T ^a,b   Jasinskiene, Nijole ^b   Tretiakov, Mikhail ^b   Thiery, Isabelle ^c   Zettor, Agnès ^c   Bourgouin, Catherine ^c,d   James, Anthony A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c INSTITUT PASTEUR   (France)

^d CNRS   (France)

Author keywords

Genetic engineering; Mosquito vector; Population replacement

Indexed keywords

CHITINASE; CIRCUMSPOROZOITE PROTEIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

ANOPHELES STEPHENSI; ARTICLE; CONTROLLED STUDY; GENE LOCATION; MALARIA FALCIPARUM; MOLECULAR DOCKING; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; TRANSGENIC ORGANISM;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANOPHELES; BINDING SITES; CULICIDAE; FEMALE; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC ENGINEERING; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MODELS, GENETIC; PLASMIDS; PLASMODIUM FALCIPARUM; SINGLE-CHAIN ANTIBODIES; SPOROZOITES; TRANSGENES;

ANOPHELES STEPHENSI; PLASMODIUM FALCIPARUM;

EID: 84863944540     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1207738109     Document Type: Article

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