Development of transgenic fungi that kill human malaria parasites in mosquitoes

Science

Volumn 331, Issue 6020, 2011, Pages 1074-1077

  Fang, Weiguo ^a   Vega Rodríguez, Joel ^b   Ghosh, Anil K ^b   Jacobs Lorena, Marcelo ^b   Kang, Angray ^c   St Leger, Raymond J ^a  

^a University of Maryland   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF WESTMINSTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; HYBRID PROTEIN; PEPTIDE; SALIVARY GLAND AND MIDGUT PEPTIDE 1; SCORPINE; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG;

ANTIBODY; BIOCONTROL AGENT; BIOLOGICAL CONTROL; BLOOD; GENE EXPRESSION; GENETICALLY MODIFIED ORGANISM; INFECTIOUS DISEASE; INHIBITION; MALARIA; MOSQUITO; PROTEIN; RECOMBINATION; SALIVA; TOXIN;

ANIMAL EXPERIMENT; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; FUNGAL STRAIN; GENE EXPRESSION; HEMOLYMPH; METARHIZIUM ANISOPLIAE; MOSQUITO; NONHUMAN; PARASITE TRANSMISSION; PLASMODIUM; PRIORITY JOURNAL; SALIVARY GLAND; SPOROZOITE; TRANSGENIC PLANT;

ANIMALS; ANOPHELES GAMBIAE; ANTIBODIES, PROTOZOAN; BASE SEQUENCE; CLONING, MOLECULAR; DEFENSINS; FEEDING BEHAVIOR; FEMALE; HEMOLYMPH; HUMANS; INSECT VECTORS; MALARIA, FALCIPARUM; METARHIZIUM; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PEST CONTROL, BIOLOGICAL; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; SALIVARY GLANDS; SPORES, FUNGAL; SPOROZOITES; TRANSFORMATION, GENETIC; TRANSGENES;

FUNGI; METARHIZIUM; METARHIZIUM ANISOPLIAE;

EID: 79952057173     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1199115     Document Type: Article

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