Mechanisms for endothelial monocyte-activating polypeptide-II-induced opening of the blood-tumor barrier

Journal of Molecular Neuroscience

Volumn 47, Issue 2, 2012, Pages 408-417

  Li, Zhen ^a   Liu, Yun Hui ^a   Xue, Yi Xue ^a   Liu, Li Bo ^a   Xie, Hui ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

ATP synthase subunit; Blood tumor barrier; Endothelial monocyte activating polypeptide II; Permeability; Protein kinase C; Tight junction

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; ENDOTHELIAL MONOCYTE ACTIVATING POLYPEPTIDE II; OCCLUDIN; PROTEIN KINASE C; PROTEIN ZO1; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE ALPHA SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; BLOOD TUMOR BARRIER; BLOOD VESSEL PERMEABILITY; BRAIN BLOOD FLOW; BRAIN BLOOD VESSEL; BRAIN MICROVASCULAR ENDOTHELIAL CELL; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; CYTOSOL; ENDOTHELIUM CELL; IN VITRO STUDY; NONHUMAN; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TIGHT JUNCTION;

ANIMALS; ANIMALS, NEWBORN; BLOOD-BRAIN BARRIER; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL MEMBRANE PERMEABILITY; CYTOKINES; GLIOMA; NEOPLASM PROTEINS; PRIMARY CELL CULTURE; RATS; RATS, WISTAR; RNA-BINDING PROTEINS;

RATTUS;

EID: 84863879231     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-011-9657-5     Document Type: Article

References (30)

1. Arechaga I, Jones PC (2001) Quick guide: ATP synthase. Curr Biol 11(4):R117 (Pubitemid 32185313)
2. Augereau O, Claverol S, Boudes N et al (2005) Identification of tyrosinephosphorylated proteins of the mitochondrial oxidative phosphorylation machinery. Cell Mol Life Sci 62(13):1478-1488 (Pubitemid 40922950)
3. Barnett G, Jakobsen AM, Tas M et al (2000) Prostate adenocarcinoma cells release the novel proinflammatory polypeptide EMAP-II in response to stress. Cancer Res 60(11):2850-2857 (Pubitemid 30395805)
4. Berger AC, Alexander HR, Tang G et al (2000) Endothelial monocyte activating polypeptide II induces endothelial cell apoptosis and may inhibit tumor angiogenesis. Microvasc Res 60(1):70-80 (Pubitemid 30456829)
5. Black KL, Ningaraj NS (2004) Modulation of brain tumor capillaries for enhanced drug delivery selectively to brain tumor. Cancer Control 11(3):165-173 (Pubitemid 38758221)
6. 1subunit of ATP synthase (IF1) modulates the activity of angiostatin on the endothelial cell surface. J Biol Chem 280(3):1740-1745
7. Chang SY, Park SG, Kim S et al (2002) Interaction of the C-terminal Domain of p43 and the alpha subunit of ATP Synthase. Its functional implication in endothelial cell proliferation. J Biol Chem 277(10):8388-8394 (Pubitemid 34968299)
8. Fleegal MA, Hom S, Borg LK et al (2005) Activation of PKC modulates blood-brain barrier endothelial cell permeability changes induced by hypoxia and posthypoxic reoxyenation. Am J Physiol Heart Circ Physiol 289(5):H2012-H2019 (Pubitemid 41507352)
9. Gloor SM, Wachtel M, Bolliger MF et al (2001) Molecular and cellular permeability control at the blood-brain barrier. Brain Res Brain Res Rev 36(2-3):258-264 (Pubitemid 33020756)
10. Guo M, Wu MH, Korompai F et al (2003) Upregulation of PKC gene and isozymes in cardiovascular tissues during early stages of experimental diabetes. Physiol Genomics 12(2):139-146 (Pubitemid 37139693)
11. Harhaj NS, Antonetti DA (2004) Regulation of tight junctions and loss of barrier function in pathophysiology. Int J Biochem Cell Biol 36(7):1206-1237 (Pubitemid 38519069)
12. Karczewski J, Groot J (2000) Molecular physiology and pathophysiology of tight junctions: III. Tight junction regulation by intracellular messengers: differences in response within and between epithelia. Am J Physiol Gastrointest Liver Physiol 279(4):G660-G665
13. Liu LB, Xue YX, Liu YH et al (2008) Bradykinin increases blood-tumor barrier permeability by down-regulating the expression levels of ZO-1, occludin, and claudin-5 and rearranging actin cytoskeleton. J Neurosci Res 86(5):1153-1168
14. Ma T, Xue YX (2010) RhoA-mediated potential regulation of blood-tumor barrier permeability by bradykinin. J Mol Neurosci 42(1):67-73
15. Newton AC (1997) Regulation of protein kinase C. Curr Opin Cell Biol 9(2):161-167
16. Opii WO, Nukala VN, Sultana R et al (2007) Proteomic identification of oxidized mitochondrial proteins following experimental traumatic brain injury. J Neurotrauma 24(5):772-789 (Pubitemid 46799270)
17. Qiu LB, Ding GR, Li KC et al (2010) The role of protein kinase C in the opening of blood-brain barrier induced by electromagnetic pulse. Toxicology 273(1-3):29-34
18. Ron D, Kazanietz MG (1999) New insight into the regulation of protein kinase C and novel phorbol ester receptors. FASEB J 13(13):1658-1676 (Pubitemid 29473329)
19. Schmitz HP, Lorberg A, Heinisch JJ (2002) Regulation of yeast protein kinase C activity by interaction with the small GTPase Rho1p through its aminoterminal HR1 domain. Mol Microbiol 44(3):829-840 (Pubitemid 34526592)
20. Scotet E, Martinez LO, Grant E et al (2005) Tumor recognition following Vgamma9Vdelta2 T cell receptor interactions with a surface F1-ATPase-related structure and apolipoprotein A-I. Immunity 22(1):71-80 (Pubitemid 40143452)
21. Shalak V, Guigou L, Kaminska M et al (2007) Characterization of p43 (ARF), a derivative of the p43 component of multiaminoacyltRNA synthetase complex released during apoptosis. J Biol Chem 282(15):10935-10943 (Pubitemid 47100748)
22. Siegal T, Zylber-Katz E (2002) Strategies for increasing drug delivery to the brain: focus on brain lymphoma. Clin Pharmacokinet 41(3):171-186 (Pubitemid 34415836)
23. Slater SJ, Seiz JL, Stagliano BA et al (2001) Interaction of protein kinase C isozysmes with Rho GTPases. Biochemistry 40(14):4437-4445 (Pubitemid 32319589)
24. Stamatovic SM, Dimitrijevic OB, Keep RF et al (2006) Protein kinase Cα-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. J Biol Chem 281(13):8379-8388 (Pubitemid 43847939)
25. Wang YB, Peng C, Liu YH (2007) Low dose of bradykinin selectively increases intracellular calcium in glioma cells. J Neurol Sci 258(1-2):44-51 (Pubitemid 46874476)
26. Willis CL, Meske DS, Davis TP (2010) PKC activation modulates reversible increase in cortical blood-brain barrier permeability and tight junction protein expression during hypoxia and posthypoxic reoxyenation. J Cereb Blood Flow Metab 30(11):1847-1859
27. Wolburg H, Lippoldt A (2002) Tight junctions of the blood-brain barrier: development, composition and regulation. Vascul Pharmacol 38(6):323-337 (Pubitemid 36398254)
28. Xie H, Xue YX, Liu LB et al (2010) Endothelial-monocyte-activating polypeptide II increases blood-tumor barrier permeability by down-regulating the expression of tight junction associated proteins. Brain Res 1319:13-20
29. Xie H, Xue YX, Liu LB et al (2011) Role of RhoA/ROCK signaling in Endothelial- monocyte-activating polypeptide II opening of the blood-tumor barrier. J Mol Neurosci (Accepted)
30. Yuan SY (2002) Protein kinase signaling in the modulation of microvascular permeability. Vascul Pharmacol 39(4-5):213-223