Truncated nucleosides as A3 adenosine receptor ligands: Combined 2-arylethynyl and bicyclohexane substitutions

ACS Medicinal Chemistry Letters

Volumn 3, Issue 7, 2012, Pages 596-601

  Tosh, Dilip K ^a   Paoletta, Silvia ^a   Phan, Khai ^a   Gao, Zhan Guo ^a   Jacobson, Kenneth A ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

adenosine receptor; G protein coupled receptor; molecular modeling; purines; radioligand binding; structure activity relationship

Indexed keywords

ADENOSINE A3 RECEPTOR; ADENOSINE A3 RECEPTOR AGONIST; ADENOSINE A3 RECEPTOR ANTAGONIST; ADENYLATE CYCLASE; ALKYL GROUP; BICYCLO COMPOUND; CYCLOHEXANE; LIGAND; NUCLEOSIDE DERIVATIVE;

ANIMAL CELL; ARTICLE; DRUG SELECTIVITY; HUMAN; HUMAN CELL; HUMAN TISSUE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; SUBSTITUTION REACTION;

EID: 84863854566     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml300107e     Document Type: Article

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