Statistical evaluation of mortality in long-term carcinogenicity bioassays using a Williams-type procedure

Regulatory Toxicology and Pharmacology

Volumn 64, Issue 1, 2012, Pages 26-34

  Herberich, Esther ^a   Hothorn, Ludwig A ^b  

^a UNIVERSITY OF MUNICH   (Germany)

^b LEIBNIZ UNIVERSITY HANNOVER   (Germany)

Author keywords

Mortality; Proof of hazard; Proof of safety; Statistical evaluation; Survival

Indexed keywords

ANALYTIC METHOD; ANALYTICAL ERROR; ARTICLE; BIOASSAY; CALCULATION; CARCINOGENICITY; COMPUTER ANALYSIS; COMPUTER PROGRAM; CONTROL GROUP; DATA ANALYSIS; HAZARD ASSESSMENT; HAZARD RATIO; MATHEMATICAL COMPUTING; MORTALITY; PRIORITY JOURNAL; RISK ASSESSMENT; SEX DIFFERENCE; SIMULATION; SPECIES DIFFERENCE; STATISTICAL ANALYSIS; SURVIVAL; TOXICITY TESTING;

ANIMALS; BIOMETRY; CARCINOGENICITY TESTS; CARCINOGENS; DATA INTERPRETATION, STATISTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; KAPLAN-MEIER ESTIMATE; MALE; MICE; MORTALITY; MULTIVARIATE ANALYSIS; NEOPLASMS; PESTICIDE SYNERGISTS; PIPERONYL BUTOXIDE; PROPORTIONAL HAZARDS MODELS; RATS; RISK ASSESSMENT; TOXICOLOGY; XENOBIOTICS;

EID: 84863853895     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2012.06.014     Document Type: Article

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