LmrTX, a basic PLA2 (D49) purified from Lachesis muta rhombeata snake venom with enzymatic-related antithrombotic and anticoagulant activity

Toxicon

Volumn 60, Issue 5, 2012, Pages 773-781

  Damico, Daniela C S ^a   Vassequi Silva, T ^a   Torres Huaco, F D ^a   Nery Diez, A C C ^a   de Souza, R C G ^b   Da Silva, S L ^c   Vicente, C P ^a   Mendes, C B ^a   Antunes, E ^a   Werneck, C C ^a   Marangoni, Sérgio ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b Hospitalar Foundation of Itacaré   (Brazil)

^c FEDERAL UNIVERSITY OF SÃO JOÃO DEL REI   (Brazil)

Author keywords

Anticoagulant activity; Arterial thrombosis; Lachesis muta rhombeata venom; Phospholipase A2; Photochemical injury; Platelet aggregation

Indexed keywords

ADENOSINE DIPHOSPHATE; BUFFER; CB1; CB2; HISTIDINE; LMRTX; LMTX I; LMTX II; PHOSPHOLIPASE A; PHOSPHOLIPASE A2; SNAKE VENOM; THROMBIN; UNCLASSIFIED DRUG;

ALKYLATION; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICOAGULATION; ARTICLE; CAROTID ARTERY OBSTRUCTION; CAROTID ARTERY THROMBOSIS; CHROMATOGRAPHY; CONTROLLED STUDY; CROTALUS; CROTALUS DURISSUS TERRIFICUS; DRUG DETERMINATION; DRUG ISOLATION; DRUG MECHANISM; DRUG PURIFICATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; EX VIVO STUDY; FRACTIONATION; GEL PERMEATION CHROMATOGRAPHY; LACHESIS MUTA MUTA; LACHESIS MUTA RHOMBEATA; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTHROMBIN TIME; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEQUENCE HOMOLOGY; SNAKE; STRUCTURE ACTIVITY RELATION; THROMBOCYTE AGGREGATION INHIBITION; THROMBOGENESIS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; CROTALID VENOMS; MASS SPECTROMETRY; MICE; MOLECULAR SEQUENCE DATA; PHOSPHOLIPASES A2; SEQUENCE ANALYSIS, DNA; SPECIES SPECIFICITY; THROMBOSIS;

ANIMALIA; CROTALUS DURISSUS TERRIFICUS; LACHESIS MUTA MUTA; LACHESIS MUTA RHOMBEATA;

EID: 84863842064     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2012.06.010     Document Type: Article

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