-
1
-
-
70449464779
-
Activating systemic autoimmunity: Bs, Ts, and Tolls
-
Shlomchik MJ. Activating systemic autoimmunity: Bs, Ts, and Tolls. Curr Opin Immunol 2009;21:626-33.
-
(2009)
Curr Opin Immunol
, vol.21
, pp. 626-633
-
-
Shlomchik, M.J.1
-
2
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio TA, Collins FS, Cox NJ, et al. Finding the missing heritability of complex diseases. Nature 2009;461:747-53.
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
-
3
-
-
67649197343
-
Interleukin 17 acts in synergy with B cellactivating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus
-
Doreau A, Belot A, Bastid J, et al. Interleukin 17 acts in synergy with B cellactivating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus. Nat Immunol 2009;10:778-85.
-
(2009)
Nat Immunol
, vol.10
, pp. 778-785
-
-
Doreau, A.1
Belot, A.2
Bastid, J.3
-
5
-
-
79960285335
-
The IgH locus 3′ regulatory region: Pulling the strings from behind
-
Pinaud E, Marquet M, Fiancette R, et al. The IgH locus 3′ regulatory region: pulling the strings from behind. Adv Immunol 2011;110:27-70.
-
(2011)
Adv Immunol
, vol.110
, pp. 27-70
-
-
Pinaud, E.1
Marquet, M.2
Fiancette, R.3
-
6
-
-
33845974842
-
Regulation of epsilon germline transcription and switch region mutations by IgH locus 3′ enhancers in transgenic mice
-
DOI 10.1182/blood-2006-02-005355
-
Laurencikiene J, Tamosiunas V, Severinson E. Regulation of epsilon germline transcription and switch region mutations by IgH locus 3′ enhancers in transgenic mice. Blood 2007;109:159-67. (Pubitemid 46053057)
-
(2007)
Blood
, vol.109
, Issue.1
, pp. 159-167
-
-
Laurencikiene, J.1
Tamosiunas, V.2
Severinson, E.3
-
7
-
-
73349098453
-
Switch recombination and somatic hypermutation are controlled by the heavy chain 3′ enhancer region
-
Dunnick WA, Collins JT, Shi J, et al. Switch recombination and somatic hypermutation are controlled by the heavy chain 3′ enhancer region. J Exp Med 2009;206:2613-23.
-
(2009)
J Exp Med
, vol.206
, pp. 2613-2623
-
-
Dunnick, W.A.1
Collins, J.T.2
Shi, J.3
-
8
-
-
77956899151
-
Genomic deletion of the whole IgH 3′ regulatory region (hs3a, hs1,2, hs3b, and hs4) dramatically affects class switch recombination and Ig secretion to all isotypes
-
Vincent-Fabert C, Fiancette R, Pinaud E, et al. Genomic deletion of the whole IgH 3′ regulatory region (hs3a, hs1,2, hs3b, and hs4) dramatically affects class switch recombination and Ig secretion to all isotypes. Blood 2010;116:1895-8.
-
(2010)
Blood
, vol.116
, pp. 1895-1898
-
-
Vincent-Fabert, C.1
Fiancette, R.2
Pinaud, E.3
-
9
-
-
80051688660
-
Dynamic changes in binding of immunoglobulin heavy chain 3′ regulatory region to protein factors during class switching
-
Chatterjee S, Ju Z, Hassan R, et al. Dynamic changes in binding of immunoglobulin heavy chain 3′ regulatory region to protein factors during class switching. J Biol Chem 2011;286:29303-12.
-
(2011)
J Biol Chem
, vol.286
, pp. 29303-29312
-
-
Chatterjee, S.1
Ju, Z.2
Hassan, R.3
-
10
-
-
0030240127
-
Palindromic structure of the IgH 3′ locus control region
-
Chauveau C, Cogné M. Palindromic structure of the IgH 3′ locus control region. Nat Genet 1996;14:15-6.
-
(1996)
Nat Genet
, vol.14
, pp. 15-16
-
-
Chauveau, C.1
Cogné, M.2
-
11
-
-
79952544887
-
Position and sequence conservation in amniota of polymorphic enhancer HS1.2 within the palindrome of IgH 3′ regulatory region
-
D'Addabbo P, Scascitelli M, Giambra V, et al. Position and sequence conservation in amniota of polymorphic enhancer HS1.2 within the palindrome of IgH 3′ regulatory region. BMC Evol Biol 2011;11:71.
-
(2011)
BMC Evol Biol
, vol.11
, pp. 71
-
-
D'Addabbo, P.1
Scascitelli, M.2
Giambra, V.3
-
12
-
-
0030886813
-
Enhancer complexes located downstream of both human immunoglobulin Calpha genes
-
DOI 10.1084/jem.186.6.845
-
Mills FC, Harindranath N, Mitchell M, et al. Enhancer complexes located downstream of both human immunoglobulin Calpha genes. J Exp Med 1997;186:845-58. (Pubitemid 27407346)
-
(1997)
Journal of Experimental Medicine
, vol.186
, Issue.6
, pp. 845-858
-
-
Mills, F.C.1
Harindranath, N.2
Mitchell, M.3
Max, E.E.4
-
13
-
-
14744291914
-
Evolution of human IgH3′EC duplicated structures: Both enhancers HS1,2 are polymorphic with variation of transcription factor's consensus sites
-
DOI 10.1016/j.gene.2004.10.009
-
Giambra V, Fruscalzo A, Giufré M, et al. Evolution of human IgH3′EC duplicated structures: both enhancers HS1,2 are polymorphic with variation of transcription factor's consensus sites. Gene 2005;346:105-14. (Pubitemid 40332628)
-
(2005)
Gene
, vol.346
, pp. 105-114
-
-
Giambra, V.1
Fruscalzo, A.2
Giufre, M.3
Martinez-Labarga, C.4
Favaro, M.5
Rocchi, M.6
Frezza, D.7
-
14
-
-
0034743941
-
Polymorphism of the human alpha1 immunoglobulin gene 3′ enhancer hs1,2 and its relation to gene expression
-
DOI 10.1046/j.1365-2567.2001.01217.x
-
Denizot Y, Pinaud E, Aupetit C, et al. Polymorphism of the human alpha1 immunoglobulin gene 3′ enhancer hs1,2 and its relation to gene expression. Immunology 2001;103:35-40. (Pubitemid 32454522)
-
(2001)
Immunology
, vol.103
, Issue.1
, pp. 35-40
-
-
Denizot, Y.1
Pinaud, E.2
Aupetit, C.3
Le, M.C.4
Magnoux, E.5
Aldigier, J.C.6
Cogne, M.7
-
15
-
-
0035884781
-
HS1,2 enhancer regulation of germline epsilon and gamma2b promoters in murine B lymphocytes: Evidence for specific promoter-enhancer interactions
-
Laurencikiene J, Deveikaite V, Severinson E. HS1,2 enhancer regulation of germline epsilon and gamma2b promoters in murine B lymphocytes: evidence for specific promoter-enhancer interactions. J Immunol 2001;167:3257-65. (Pubitemid 32852566)
-
(2001)
Journal of Immunology
, vol.167
, Issue.6
, pp. 3257-3265
-
-
Laurencikiene, J.1
Deveikaite, V.2
Severinson, E.3
-
16
-
-
4744337615
-
The HoxC4 homeodomain protein mediates activation of the immunoglobulin heavy chain 3′ hs1,2 enhancer in human B cells: Relevance to class switch DNA recombination
-
DOI 10.1074/jbc.M407496200
-
Kim EC, Edmonston CR, Wu X, et al. The HoxC4 homeodomain protein mediates activation of the immunoglobulin heavy chain 3′ hs1,2 enhancer in human B cells. Relevance to class switch DNA recombination. J Biol Chem 2004;279:42258-69. (Pubitemid 39313675)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.40
, pp. 42258-42269
-
-
Kim, E.C.1
Edmonston, C.R.2
Wu, X.3
Schaffer, A.4
Casali, P.5
-
17
-
-
0032525053
-
3' IgH enhancer elements shift synergistic interactions during B cell development
-
Ong J, Stevens S, Roeder RG, et al. 3′ IgH enhancer elements shift synergistic interactions during B cell development. J Immunol 1998;160:4896-903. (Pubitemid 28215324)
-
(1998)
Journal of Immunology
, vol.160
, Issue.10
, pp. 4896-4903
-
-
Ong, J.1
Stevens, S.2
Roeder, R.G.3
Eckhardt, L.A.4
-
18
-
-
0033624584
-
Alleles of the alpha1 immunoglobulin gene 3′ enhancer control evolution of IgA nephropathy toward renal failure
-
Aupetit C, Drouet M, Pinaud E, et al. Alleles of the alpha1 immunoglobulin gene 3′ enhancer control evolution of IgA nephropathy toward renal failure. Kidney Int 2000;58:966-71.
-
(2000)
Kidney Int
, vol.58
, pp. 966-971
-
-
Aupetit, C.1
Drouet, M.2
Pinaud, E.3
-
19
-
-
8844224103
-
Increased frequency of the immunoglobulin enhancer HS1,2 allele 2 in coeliac disease
-
DOI 10.1080/00365520410007999
-
Frezza D, Giambra V, Cianci R, et al. Increased frequency of the immunoglobulin enhancer HS1,2 allele 2 in coeliac disease. Scand J Gastroenterol 2004;39:1083-7. (Pubitemid 39536397)
-
(2004)
Scandinavian Journal of Gastroenterology
, vol.39
, Issue.11
, pp. 1083-1087
-
-
Frezza, D.1
Giambra, V.2
Cianci, R.3
Fruscalzo, A.4
Giufre, M.5
Cammarota, G.6
Martinez-Labarga, C.7
Rickards, O.8
Scibilia, G.9
Sferlazzas, C.10
Bartolozzi, F.11
Starnino, S.12
Magazzu, G.13
Gasbarrini, G.B.14
Pandolfi, F.15
-
20
-
-
47349097874
-
Increased frequency of Ig heavy-chain HS1,2-A enhancer*2 allele in dermatitis herpetiformis, plaque psoriasis, and psoriatic arthritis
-
DOI 10.1038/jid.2008.40, PII JID200840
-
Cianci R, Giambra V, Mattioli C, et al. Increased frequency of Ig heavy-chain HS1,2-A enhancer*2 allele in dermatitis herpetiformis, plaque psoriasis, and psoriatic arthritis. J Invest Dermatol 2008;128:1920-4. (Pubitemid 352001222)
-
(2008)
Journal of Investigative Dermatology
, vol.128
, Issue.8
, pp. 1920-1924
-
-
Cianci, R.1
Giambra, V.2
Mattioli, C.3
Esposito, M.4
Cammarota, G.5
Scibilia, G.6
Magazzu, G.7
Orlando, A.8
Sandri, G.9
Bianchi, L.10
Gasbarrini, G.B.11
Pandolfi, F.12
Frezza, D.13
-
21
-
-
34548184865
-
Polymorphism of immunoglobulin enhancer element HS1,2A: Allele*2 associates with systemic sclerosis. Comparison with HLA-DR and DQ allele frequency
-
DOI 10.1136/ard.2006.066597
-
Frezza D, Giambra V, Tolusso B, et al. Polymorphism of immunoglobulin enhancer element HS1,2A: allele*2 associates with systemic sclerosis. Comparison with HLA-DR and DQ allele frequency. Ann Rheum Dis 2007;66:1210-5. (Pubitemid 47309739)
-
(2007)
Annals of the Rheumatic Diseases
, vol.66
, Issue.9
, pp. 1210-1215
-
-
Frezza, D.1
Giambra, V.2
Tolusso, B.3
De Santis, M.4
Bosello, S.5
Vettori, S.6
Triolo, G.7
Valentini, G.8
Ferraccioli, G.F.9
-
22
-
-
61449244651
-
Allele*2 of the HS1,2A enhancer of the Ig regulatory region associates with rheumatoid arthritis
-
Tolusso B, Frezza D, Mattioli C, et al. Allele*2 of the HS1,2A enhancer of the Ig regulatory region associates with rheumatoid arthritis. Ann Rheum Dis 2009;68:416-9.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 416-419
-
-
Tolusso, B.1
Frezza, D.2
Mattioli, C.3
-
23
-
-
62649145611
-
Allelic frequencies of 3′ Ig heavy chain locus enhancer HS1,2-A associated with Ig levels in patients with schizophrenia
-
Frezza D, Giambra V, Mattioli C, et al. Allelic frequencies of 3′ Ig heavy chain locus enhancer HS1,2-A associated with Ig levels in patients with schizophrenia. Int J Immunopathol Pharmacol 2009;22:115-23.
-
(2009)
Int J Immunopathol Pharmacol
, vol.22
, pp. 115-123
-
-
Frezza, D.1
Giambra, V.2
Mattioli, C.3
-
24
-
-
76249103100
-
Allele*1 of HS1.2 enhancer associates with selective IgA deficiency and IgM concentration
-
Giambra V, Cianci R, Lolli S, et al. Allele*1 of HS1.2 enhancer associates with selective IgA deficiency and IgM concentration. J Immunol 2009;183:8280-5.
-
(2009)
J Immunol
, vol.183
, pp. 8280-8285
-
-
Giambra, V.1
Cianci, R.2
Lolli, S.3
-
25
-
-
0020436689
-
The 1982 revised criteria for the classification of systemic lupus erythrematosus
-
DOI 10.1002/art.1780251101
-
Tan EM, Cohen AS, Fries JF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982;25:1271-7. (Pubitemid 13221242)
-
(1982)
Arthritis and Rheumatism
, vol.25
, Issue.11
, pp. 1271-1277
-
-
Tan, E.M.1
Cohen, A.S.2
Fries, J.F.3
-
26
-
-
0031229830
-
Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus
-
Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1997;40:1725.
-
(1997)
Arthritis Rheum
, vol.40
, pp. 1725
-
-
Hochberg, M.C.1
-
27
-
-
0024380087
-
Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells
-
Schreiber E, Matthias P, Müller MM, et al. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res 1989;17:6419. (Pubitemid 19198635)
-
(1989)
Nucleic Acids Research
, vol.17
, Issue.15
, pp. 6419
-
-
Schreiber, E.1
Matthias, P.2
Muller, M.M.3
Schaffner, W.4
-
28
-
-
0026708394
-
Independent modes of transcriptional activation by the p50 and p65 subunits of NF-kappa B
-
Fujita T, Nolan GP, Ghosh S, et al. Independent modes of transcriptional activation by the p50 and p65 subunits of NF-kappa B. Genes Dev 1992;6:775-87.
-
(1992)
Genes Dev
, vol.6
, pp. 775-787
-
-
Fujita, T.1
Nolan, G.P.2
Ghosh, S.3
-
29
-
-
0030584725
-
Regulation of 3′ IgH enhancers by a common set of factors, including kappaB-binding proteins
-
Michaelson JS, Singh M, Snapper CM, et al. Regulation of 3′ IgH enhancers by a common set of factors, including kappa B-binding proteins. J Immunol 1996;156:2828-39. (Pubitemid 126660629)
-
(1996)
Journal of Immunology
, vol.156
, Issue.8
, pp. 2828-2839
-
-
Michaelson, J.S.1
Singh, M.2
Snapper, C.M.3
Sha, W.C.4
Baltimore, D.5
Birshtein, B.K.6
-
30
-
-
0033623861
-
NF-kappaB/p50 and NF-kappaB/c-Rel differentially regulate the activity of the 3′alphaE-hsl,2 enhancer in normal murine B cells in an activation-dependent manner
-
Zelazowski P, Shen Y, Snapper CM. NF-kappaB/p50 and NF-kappaB/c-Rel differentially regulate the activity of the 3′alphaE-hsl,2 enhancer in normal murine B cells in an activation-dependent manner. Int Immunol 2000;12:1167-72. (Pubitemid 30618022)
-
(2000)
International Immunology
, vol.12
, Issue.8
, pp. 1167-1172
-
-
Zelazowski, P.1
Shen, Y.2
Snapper, C.M.3
-
31
-
-
1642536443
-
NF-kappaB and Oct-2 Synergize to Activate the Human 3′ Igh hs4 Enhancer in B Cells
-
Sepulveda MA, Emelyanov AV, Birshtein BK. NF-kappa B and Oct-2 synergize to activate the human 3′ IgH hs4 enhancer in B cells. J Immunol 2004;172:1054-64. (Pubitemid 38113765)
-
(2004)
Journal of Immunology
, vol.172
, Issue.2
, pp. 1054-1064
-
-
Sepulveda, M.A.1
Emelyanov, A.V.2
Birshtein, B.K.3
-
32
-
-
66549095183
-
BAFF-R promotes cell proliferation and survival through interaction with IKKbeta and NF-kappaB/c-Rel in the nucleus of normal and neoplastic B-lymphoid cells
-
Fu L, Lin-Lee YC, Pham LV, et al. BAFF-R promotes cell proliferation and survival through interaction with IKKbeta and NF-kappaB/c-Rel in the nucleus of normal and neoplastic B-lymphoid cells. Blood 2009;113:4627-36.
-
(2009)
Blood
, vol.113
, pp. 4627-4636
-
-
Fu, L.1
Lin-Lee, Y.C.2
Pham, L.V.3
-
33
-
-
84863827170
-
IkB kinase signalling is essential for maintenance of mature B cells
-
Pasparakis M, Schmidt-Supprian M, Rajewsky K. IkB kinase signalling is essential for maintenance of mature B cells. J Exp Med 2002;193:417-26.
-
(2002)
J Exp Med
, vol.193
, pp. 417-426
-
-
Pasparakis, M.1
Schmidt-Supprian, M.2
Rajewsky, K.3
-
34
-
-
0035910742
-
IkappaB kinase alpha is essential for mature B cell development and function
-
DOI 10.1084/jem.193.4.417
-
Kaisho T, Takeda K, Tsujimura T, et al. IkappaB kinase alpha is essential for mature B cell development and function. J Exp Med 2001;193:417-26. (Pubitemid 32524473)
-
(2001)
Journal of Experimental Medicine
, vol.193
, Issue.4
, pp. 417-426
-
-
Kaisho, T.1
Takeda, K.2
Tsujimura, T.3
Kawai, T.4
Nomura, F.5
Terada, N.6
Akira, S.7
-
35
-
-
80052887167
-
A critical role for the NFkB pathway in multiple myeloma
-
Demchenko YN, Kuehl WM. A critical role for the NFkB pathway in multiple myeloma. Oncotarget 2010;1:59-68.
-
(2010)
Oncotarget
, vol.1
, pp. 59-68
-
-
Demchenko, Y.N.1
Kuehl, W.M.2
-
36
-
-
65549087544
-
Crucial role for BAFF-BAFF-R signaling in the survival and maintenance of mature B cells
-
Rauch M, Tussiwand R, Bosco N, et al. Crucial role for BAFF-BAFF-R signaling in the survival and maintenance of mature B cells. PLoS ONE 2009;4:e5456.
-
(2009)
PLoS ONE
, vol.4
-
-
Rauch, M.1
Tussiwand, R.2
Bosco, N.3
-
37
-
-
9144220762
-
Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway
-
DOI 10.1182/blood-2003-02-0540
-
Kern C, Cornuel JF, Billard C, et al. Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway. Blood 2004;103:679-88. (Pubitemid 38145555)
-
(2004)
Blood
, vol.103
, Issue.2
, pp. 679-688
-
-
Kern, C.1
Cornuel, J.-F.2
Billard, C.3
Tang, R.4
Rouillard, D.5
Stenou, V.6
Defrance, T.7
Ajchenbaum-Cymbalista, F.8
Simonin, P.-Y.9
Feldblum, S.10
Kolb, J.-P.11
-
38
-
-
13444270605
-
Chromatin architecture near a potential 3′ end of the Igh locus involves modular regulation of histone modifications during B-cell development and in vivo occupancy at CTCF sites
-
DOI 10.1128/MCB.25.4.1511-1525.2005
-
Garrett FE, Emelyanov AV, Sepulveda MA, et al. Chromatin architecture near a potential 3′ end of the igh locus involves modular regulation of histone modifications during B cell development and in vivo occupancy at CTCF sites. Mol Cell Biol 2005;25:1511-25. (Pubitemid 40204926)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.4
, pp. 1511-1525
-
-
Garrett, F.E.1
Emelyanov, A.V.2
Sepulveda, M.A.3
Flanagan, P.4
Volpi, S.5
Li, F.6
Loukinov, D.7
Eckhardt, L.A.8
Lobanenkov, V.V.9
Birshtein, B.K.10
-
39
-
-
52649138951
-
Pax5 and linker histone H1 coordinate DNA methylation and histone modifications in the 3′ regulatory region of the immunoglobulin heavy chain locus
-
Giambra V, Volpi S, Emelyanov AV, et al. Pax5 and linker histone H1 coordinate DNA methylation and histone modifications in the 3′ regulatory region of the immunoglobulin heavy chain locus. Mol Cell Biol 2008;28:6123-33.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6123-6133
-
-
Giambra, V.1
Volpi, S.2
Emelyanov, A.V.3
-
40
-
-
36148940618
-
S-S Synapsis during Class Switch Recombination Is Promoted by Distantly Located Transcriptional Elements and Activation-Induced Deaminase
-
DOI 10.1016/j.immuni.2007.09.007, PII S1074761307004608
-
Wuerffel R, Wang L, Grigera F, et al. S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase. Immunity 2007;27:711-22. (Pubitemid 350110545)
-
(2007)
Immunity
, vol.27
, Issue.5
, pp. 711-722
-
-
Wuerffel, R.1
Wang, L.2
Grigera, F.3
Manis, J.4
Selsing, E.5
Perlot, T.6
Alt, F.W.7
Cogne, M.8
Pinaud, E.9
Kenter, A.L.10
-
41
-
-
40949152727
-
Association between the Igk and Igh immunoglobulin loci mediated by the 3′ Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells
-
DOI 10.1038/ni1567, PII NI1567
-
Hewitt SL, Farmer D, Marszalek K, et al. Association between the Igk and Igh immunoglobulin loci mediated by the 3′ Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells. Nat Immunol 2008;9:396-404. (Pubitemid 351405109)
-
(2008)
Nature Immunology
, vol.9
, Issue.4
, pp. 396-404
-
-
Hewitt, S.L.1
Farmer, D.2
Marszalek, K.3
Cadera, E.4
Liang, H.-E.5
Xu, Y.6
Schlissel, M.S.7
Skok, J.A.8
|