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Volumn 120, Issue 8, 2012, Pages 635-639

Mutational analysis of PIK3CA, JAK2, BRAF, FOXL2, IDH1, AKT1 and EZH2 oncogenes in sarcomas

Author keywords

JAK2; Mutation; Oncogene; PIK3CA; Sarcoma

Indexed keywords

B RAF KINASE; FORKHEAD BOX PROTEIN L2; FORKHEAD TRANSCRIPTION FACTOR; ISOCITRATE DEHYDROGENASE 1; JANUS KINASE 2; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; TRANSCRIPTION FACTOR EZH2; UNCLASSIFIED DRUG;

EID: 84863831448     PISSN: 09034641     EISSN: 16000463     Source Type: Journal    
DOI: 10.1111/j.1600-0463.2012.02878.x     Document Type: Article
Times cited : (32)

References (20)
  • 3
    • 0033119006 scopus 로고    scopus 로고
    • Differential transactivation by alternative EWS-FLI1 fusion proteins correlates with clinical heterogeneity in Ewing's sarcoma
    • Lin PP, Brody RI, Hamelin AC, Bradner JE, Healey JH, Ladanyi M. Differential transactivation by alternative EWS-FLI1 fusion proteins correlates with clinical heterogeneity in Ewing's sarcoma. Cancer Res 1999;59:1428-32.
    • (1999) Cancer Res , vol.59 , pp. 1428-1432
    • Lin, P.P.1    Brody, R.I.2    Hamelin, A.C.3    Bradner, J.E.4    Healey, J.H.5    Ladanyi, M.6
  • 4
    • 0028881603 scopus 로고
    • The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3
    • Fredericks WJ, Galili N, Mukhopadhyay S, Rovera G, Bennicelli J, Barr FG, et al. The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3. Mol Cell Biol 1995;15:1522-35.
    • (1995) Mol Cell Biol , vol.15 , pp. 1522-1535
    • Fredericks, W.J.1    Galili, N.2    Mukhopadhyay, S.3    Rovera, G.4    Bennicelli, J.5    Barr, F.G.6
  • 5
    • 0027276357 scopus 로고
    • Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma
    • Rabbitts TH, Forster A, Larson R, Nathan P. Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma. Nat Genet 1993;4:175-80.
    • (1993) Nat Genet , vol.4 , pp. 175-180
    • Rabbitts, T.H.1    Forster, A.2    Larson, R.3    Nathan, P.4
  • 12
    • 75749124332 scopus 로고    scopus 로고
    • Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
    • Morin RD, Johnson NA, Severson TM, Mungall AJ, An J, Goya R, et al. Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin. Nat Genet 2010;42:181-5.
    • (2010) Nat Genet , vol.42 , pp. 181-185
    • Morin, R.D.1    Johnson, N.A.2    Severson, T.M.3    Mungall, A.J.4    An, J.5    Goya, R.6
  • 13
    • 33750711381 scopus 로고    scopus 로고
    • Rare mutations of the PIK3CA gene in malignancies of the hematopoietic system as well as endometrium, ovary, prostate and osteosarcomas, and discovery of a PIK3CA pseudogene
    • Müller CI, Miller CW, Hofmann WK, Gross ME, Walsh CS, Kawamata N, et al. Rare mutations of the PIK3CA gene in malignancies of the hematopoietic system as well as endometrium, ovary, prostate and osteosarcomas, and discovery of a PIK3CA pseudogene. Leuk Res 2007;31:27-32.
    • (2007) Leuk Res , vol.31 , pp. 27-32
    • Müller, C.I.1    Miller, C.W.2    Hofmann, W.K.3    Gross, M.E.4    Walsh, C.S.5    Kawamata, N.6
  • 14
    • 84861333261 scopus 로고    scopus 로고
    • High-throughput genotyping in osteosarcoma identifies multiple mutations in phosphoinositide-3-kinase and other oncogenes
    • Choy E, Hornicek F, Macconaill L, Harmon D, Tariq Z, Garraway L, et al. High-throughput genotyping in osteosarcoma identifies multiple mutations in phosphoinositide-3-kinase and other oncogenes. Cancer 2012. 118:2905-14.
    • (2012) Cancer , vol.118 , pp. 2905-2914
    • Choy, E.1    Hornicek, F.2    Macconaill, L.3    Harmon, D.4    Tariq, Z.5    Garraway, L.6
  • 15
    • 80053308774 scopus 로고    scopus 로고
    • Spectrum of KIT/PDGFRA/BRAF mutations and Phosphatidylinositol-3-Kinase pathway gene alterations in gastrointestinal stromal tumors (GIST)
    • Daniels M, Lurkin I, Pauli R, Erbstösser E, Hildebrandt U, Hellwig K, et al. Spectrum of KIT/PDGFRA/BRAF mutations and Phosphatidylinositol-3-Kinase pathway gene alterations in gastrointestinal stromal tumors (GIST). Cancer Lett 2011;312:43-54.
    • (2011) Cancer Lett , vol.312 , pp. 43-54
    • Daniels, M.1    Lurkin, I.2    Pauli, R.3    Erbstösser, E.4    Hildebrandt, U.5    Hellwig, K.6
  • 16
    • 79959722200 scopus 로고    scopus 로고
    • Immunohistochemical analysis of 1844 human epithelial and haematopoietic tumours and sarcomas for IDH1R132H mutation
    • Sahm F, Capper D, Meyer J, Hartmann C, Herpel E, Andrulis M, et al. Immunohistochemical analysis of 1844 human epithelial and haematopoietic tumours and sarcomas for IDH1R132H mutation. Histopathology 2011;58:1167-72.
    • (2011) Histopathology , vol.58 , pp. 1167-1172
    • Sahm, F.1    Capper, D.2    Meyer, J.3    Hartmann, C.4    Herpel, E.5    Andrulis, M.6
  • 18
    • 20044388328 scopus 로고    scopus 로고
    • PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas
    • Lee JW, Soung YH, Kim SY, Lee HW, Park WS, Nam SW, et al. PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas. Oncogene 2005;24:1477-80.
    • (2005) Oncogene , vol.24 , pp. 1477-1480
    • Lee, J.W.1    Soung, Y.H.2    Kim, S.Y.3    Lee, H.W.4    Park, W.S.5    Nam, S.W.6
  • 19
    • 0033600179 scopus 로고    scopus 로고
    • Alterations of Fas (Apo-1/CD95) gene in non-small cell lung cancer
    • Lee SH, Shin MS, Park WS, Kim SY, Kim HS, Han JY, et al. Alterations of Fas (Apo-1/CD95) gene in non-small cell lung cancer. Oncogene 1999;18:3754-60.
    • (1999) Oncogene , vol.18 , pp. 3754-3760
    • Lee, S.H.1    Shin, M.S.2    Park, W.S.3    Kim, S.Y.4    Kim, H.S.5    Han, J.Y.6
  • 20
    • 0026794668 scopus 로고
    • The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes: cause and consequences
    • Krawczak M, Reiss J, Cooper DN. The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes: cause and consequences. Human Genet 1992;90:41-54.
    • (1992) Human Genet , vol.90 , pp. 41-54
    • Krawczak, M.1    Reiss, J.2    Cooper, D.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.