Plasma renin activity and the aldosterone-to-renin ratio are associated with the development of chronic kidney disease: The Ohasama Study

Journal of Hypertension

Volumn 30, Issue 8, 2012, Pages 1632-1638

  Terata, Shiho ^a   Kikuya, Masahiro ^a   Satoh, Michihiro ^a   Ohkubo, Takayoshi ^a,b   Hashimoto, Takanao ^a   Hara, Azusa ^c   Hirose, Takuo ^a   Obara, Taku ^a   Metoki, Hirohito ^a   Inoue, Ryusuke ^a   Asayama, Kei ^a,f   Kanno, Atsuhiro ^a   Totsune, Kazuhito ^a,d   Hoshi, Haruhisa ^e   Satoh, Hiroshi ^g   Sato, Hiroshi ^a   Imai, Yutaka ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^c Cancer Screening Division   (Japan)

^d TOHOKU FUKUSHI UNIVERSITY   (Japan)

^e Ohasama Hospital   (Japan)

^f UNIVERSITY OF LEUVEN   (Belgium)

^g NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

Author keywords

aldosterone excess; aldosterone to renin ratio; chronic kidney disease; general population; prospective cohort study

Indexed keywords

ALDOSTERONE; CREATININE; RENIN;

ADULT; AGED; ALDOSTERONE BLOOD LEVEL; ALDOSTERONE TO RENIN RATIO; ANALYTICAL PARAMETERS; ARTICLE; BODY MASS; CHRONIC KIDNEY DISEASE; CREATININE BLOOD LEVEL; DIABETES MELLITUS; DISEASE COURSE; DRINKING; FEMALE; FOLLOW UP; GLOMERULUS FILTRATION RATE; HUMAN; HYPERCHOLESTEROLEMIA; INCIDENCE; JAPANESE; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; PROTEINURIA; SEX; SMOKING; SYSTOLIC BLOOD PRESSURE;

EID: 84863819711     PISSN: 02636352     EISSN: 14735598     Source Type: Journal    
DOI: 10.1097/HJH.0b013e328354f65b     Document Type: Article

References (42)

1. Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 2004; 351:1296-1305.
2. Ninomiya T, Kiyohara Y, Tokuda Y, Doi Y, Arima H, Harada A, et al. Impact of kidney disease and blood pressure on the development of cardiovascular disease: an overview from the Japan Arteriosclerosis Longitudinal Study. Circulation 2008; 118:2694-2701.
3. Keith DS, Nichols GA, Gullion CM, Brown JB, Smith DH. Longitudinal follow-up and outcomes among a population with chronic kidney disease in a large managed care organization. Arch Intern Med 2004; 164:659-663.
4. Nakayama M, Metoki H, Terawaki H, Ohkubo T, Kikuya M, Sato T, et al. Kidney dysfunction as a risk factor for first symptomatic stroke events in a general Japanese population: the Ohasama study. Nephrol Dial Transplant 2007; 22:1910-1915.
5. Gansevoort RT, Matsushita K, van der Velde M, Astor BC, Woodward M, Levey AS, et al. Lower estimated GFR and higher albuminuria are associated with adverse kidney outcomes. A collaborative metaanalysis of general and high-risk population cohorts. Kidney Int 2011; 80:93-104.
6. Nagata M, Ninomiya T, Doi Y, Yonemoto K, Kubo M, Hata J, et al. Trends in the prevalence of chronic kidney disease and its risk factors in a general Japanese population: the Hisayama Study. Nephrol Dial Transplant 2010; 25:2557-2564.
7. Imai E, Horio M, Watanabe T, Iseki K, Yamagata K, Hara S, et al. Prevalence of chronic kidney disease in the Japanese general population. Clin Exp Nephrol 2009; 13:621-630.
8. Yamagata K, Ishida K, Sairenchi T, Takahashi H, Ohba S, Shiigai T, et al. Risk factors for chronic kidney disease in a community-based population: a 10-year follow-up study. Kidney Int 2007; 71:159-166.
9. Taal MW, Brenner BM. Predicting initiation and progression of chronic kidney disease: developing renal risk scores. Kidney Int 2006; 70:1694-1705.
10. Fox CS, Larson MG, Leip EP, Culleton B, Wilson PW, Levy D. Predictors of new-onset kidney disease in a community-based population. JAMA 2004; 291:844-850.
11. Sarnak MJ, Levey AS, Schoolwerth AC, Coresh J, Culleton B, Hamm LL, et al. Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation 2003; 108:2154-2169.
12. Terawaki H, Yoshimura K, Hasegawa T, Matsuyama Y, Negawa T, Yamada K, et al. Oxidative stress is enhanced in correlation with renal dysfunction: examination with the redox state of albumin. Kidney Int 2004; 66:1988-1993.
13. Alvarez-Madrazo S, Padmanabhan S, Mayosi BM, Watkins H, Avery P, Wallace AM, et al. Familial and phenotypic associations of the aldosterone Renin ratio. J Clin Endocrinol Metab 2009; 94:4324-4333.
14. Tiu SC, Choi CH, Shek CC, Ng YW, Chan FK, Ng CM, Kong AP. The use of aldosterone-renin ratio as a diagnostic test for primary hyperaldosteronism and its test characteristics under different conditions of blood sampling. J Clin Endocrinol Metab 2005; 90:72-78.
15. Komiya I, Yamada T, Takasu N, Asawa T, Akamine H, Yagi N, et al. An abnormal sodium metabolism in Japanese patients with essential hypertension, judged by serum sodium distribution, renal function and the renin-aldosterone system. J Hypertens 1997; 15:65-72.
16. Rossi GP, Bernini G, Desideri G, Fabris B, Ferri C, Giacchetti G, et al. Renal damage in primary aldosteronism: results of the PAPY Study. Hypertension 2006; 48:232-238.
17. Fox CS, Gona P, Larson MG, Selhub J, Tofler G, Hwang SJ, et al. A multimarker approach to predict incident CKD and microalbuminuria. J Am Soc Nephrol 2010; 21:2143-2149.
18. Jurgens G, Graudal NA. Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterols, and triglyceride. Cochrane Database Syst Rev 2004; CD004022.
19. Imai Y, Nagai K, Sakuma M, Sakuma H, Nakatsuka H, Satoh H, et al. Ambulatory blood pressure of adults in Ohasama, Japan. Hypertension 1993; 22:900-912.
20. Satoh M, Kikuya M, Hara A, Ohkubo T, Mori T, Metoki H, et al. Aldosterone-to-renin ratio and home blood pressure in subjects with higher and lower sodium intake: the Ohasama study. Hypertens Res 2011; 34:361-366.
21. Imai Y, Abe K, Sasaki S, Minami N, Munakata M, Sakuma H, et al. Clinical evaluation of semiautomatic and automatic devices for home blood pressure measurement: comparison between cuff-oscillometric and microphone methods. J Hypertens 1989; 7:983-990.
22. Tsubono Y, Ogawa K, Watanabe Y, Nishino Y, Tsuji I, Watanabe T, et al. Food frequency questionnaire and a screening test. Nutr Cancer 2001; 39:78-84.
23. Utsugi MT, Ohkubo T, Kikuya M, Kurimoto A, Sato RI, Suzuki K, et al. Fruit and vegetable consumption and the risk of hypertension determined by self measurement of blood pressure at home: the Ohasama study. Hypertens Res 2008; 31:1435-1443.
24. Brown CC, Kipnis V, Freedman LS, Hartman AM, Schatzkin A, Wacholder S. Energy adjustment methods for nutritional epidemiology: the effect of categorization. Am J Epidemiol 1994; 139:323-338.
25. Matsuo S, Imai E, Horio M, Yasuda Y, Tomita K, Nitta K, et al. Revised equations for estimated GFR from serum creatinine in Japan. Am J Kidney Dis 2009; 53:982-992.
26. Horio M, Orita Y. Comparison of Jaffe rate assay and enzymatic method for the measurement of creatinine clearance. Nippon Jinzo Gakkai Shi 1996; 38:296-299.
27. Otani H, Kikuya M, Hara A, Terata S, Ohkubo T, Kondo T, et al. Association of kidney dysfunction with silent lacunar infarcts and white matter hyperintensity in the general population: the Ohasama study. Cerebrovasc Dis 2010; 30:43-50.
28. Ando Y, Ito S, Uemura O, Kato T, Kimura G, Nakao T, et al. CKD Clinical Practice Guidebook. The essence of treatment for CKD patients. Clin Exp Nephrol 2009; 13:191-248.
29. Hene RJ, Boer P, Koomans HA, Mees EJ. Plasma aldosterone concentrations in chronic renal disease. Kidney Int 1982; 21:98-101.
30. Duffy SJ, Biegelsen ES, Eberhardt RT, Kahn DF, Kingwell BA, Vita JA. Low-renin hypertension with relative aldosterone excess is associated with impaired NO-mediated vasodilation. Hypertension 2005; 46:707-713.
31. Funder JW. Relative aldosterone excess: relative to what? Hypertension 2005; 46:643-644.
32. Campese VM. Salt sensitivity in hypertension. Renal and cardiovascular implications. Hypertension 1994; 23:531-550.
33. Satoh M, Kikuya M, Ohkubo T, Mori T, Metoki H, Hashimoto T, et al. Aldosterone-to-renin ratio and nocturnal blood pressure decline in a general population: the Ohasama study. J Hypertens 2011; 29:1940-1947.
34. Uzu T, Kimura G, Yamauchi A, Kanasaki M, Isshiki K, Araki S, et al. Enhanced sodium sensitivity and disturbed circadian rhythm of blood pressure in essential hypertension. J Hypertens 2006; 24:1627-1632.
35. Davidson MB, Hix JK, Vidt DG, Brotman DJ. Association of impaired diurnal blood pressure variation with a subsequent decline in glomerular filtration rate. Arch Intern Med 2006; 166:846-852.
36. Hermida RC, Ayala DE, Mojon A, Chayan L, Fontao MJ, Soler R, et al. Relative influence of the nocturnal blood pressure decline and the ambulatory blood pressure level as predictors for chronic kidney disease: The MAPEC Study. J Hypertens 2008; 26:S410-S1410.
37. Fukuda M, Mizuno M, Yamanaka T, Motokawa M, Shirasawa Y, Nishio T, et al. Patients with renal dysfunction require a longer duration until blood pressure dips during the night. Hypertension 2008; 52:1155-1160.
38. Rossing K, Schjoedt KJ, Smidt UM, Boomsma F, Parving HH. Beneficial effects of adding spironolactone to recommended antihypertensive treatment in diabetic nephropathy: a randomized, double-masked, cross-over study. Diabetes Care 2005; 28:2106-2112.
39. Williams GH, Burgess E, Kolloch RE, Ruilope LM, Niegowska J, Kipnes MS, et al. Efficacy of eplerenone versus enalapril as monotherapy in systemic hypertension. Am J Cardiol 2004; 93:990-996.
40. Navaneethan SD, Nigwekar SU, Sehgal AR, Strippoli GF. Aldosterone antagonists for preventing the progression of chronic kidney disease. Cochrane Database Syst Rev 2009; CD007004.
41. Tanabe A, Naruse M, Takagi S, Tsuchiya K, Imaki T, Takano K. Variability in the renin/aldosterone profile under random and standardized sampling conditions in primary aldosteronism. J Clin Endocrinol Metab 2003; 88:2489-2494.
42. Newton-Cheh C, Guo CY, Gona P, Larson MG, Benjamin EJ, Wang TJ, et al. Clinical and genetic correlates of aldosterone-to-renin ratio and relations to blood pressure in a community sample. Hypertension 2007; 49:846-856.