메뉴 건너뛰기




Volumn 279, Issue 15, 2012, Pages 2657-2671

Distinct biological activities of C3 and ADP-ribosyltransferase-deficient C3-E174Q

Author keywords

ADP ribosyltransferase; apoptosis; C3 exoenzyme; proliferation; RhoA

Indexed keywords

CASPASE 9; CYCLIN D; EXOENZYME C3; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; RHOB GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 84863817351     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2012.08645.x     Document Type: Article
Times cited : (22)

References (41)
  • 1
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall A, (1998) Rho GTPases and the actin cytoskeleton. Science 279, 509-514.
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 2
    • 43049090777 scopus 로고    scopus 로고
    • Growth cone collapse stimulated by both calpain- and Rho-mediated pathways
    • To KC, Church J, &, O'Connor TP, (2008) Growth cone collapse stimulated by both calpain- and Rho-mediated pathways. Neuroscience 153, 645-653.
    • (2008) Neuroscience , vol.153 , pp. 645-653
    • To, K.C.1    Church, J.2    O'Connor, T.P.3
  • 3
    • 0033983938 scopus 로고    scopus 로고
    • Regulation of endocytic traffic by rho family GTPases
    • Ellis S, &, Mellor H, (2000) Regulation of endocytic traffic by rho family GTPases. Trends Cell Biol 10, 85-88.
    • (2000) Trends Cell Biol , vol.10 , pp. 85-88
    • Ellis, S.1    Mellor, H.2
  • 5
    • 33846628565 scopus 로고    scopus 로고
    • RhoB and the mammalian Diaphanous-related formin mDia2 in endosome trafficking
    • Wallar BJ, Deward AD, Resau JH, &, Alberts AS, (2007) RhoB and the mammalian Diaphanous-related formin mDia2 in endosome trafficking. Exp Cell Res 313, 560-571.
    • (2007) Exp Cell Res , vol.313 , pp. 560-571
    • Wallar, B.J.1    Deward, A.D.2    Resau, J.H.3    Alberts, A.S.4
  • 6
    • 0032540280 scopus 로고    scopus 로고
    • RhoB is stabilized by transforming growth factor β and antagonizes transcriptional activation
    • Engel ME, Datta PK, &, Moses HL, (1998) RhoB is stabilized by transforming growth factor β and antagonizes transcriptional activation. J Biol Chem 273, 9921-9926.
    • (1998) J Biol Chem , vol.273 , pp. 9921-9926
    • Engel, M.E.1    Datta, P.K.2    Moses, H.L.3
  • 7
    • 0028849261 scopus 로고
    • The ras-related small GTP-binding protein RhoB is immediate-early inducible by DNA damaging treatments
    • Fritz G, Kaina B, &, Aktories K, (1995) The ras-related small GTP-binding protein RhoB is immediate-early inducible by DNA damaging treatments. J Biol Chem 270, 25172-25177.
    • (1995) J Biol Chem , vol.270 , pp. 25172-25177
    • Fritz, G.1    Kaina, B.2    Aktories, K.3
  • 8
    • 52049115446 scopus 로고    scopus 로고
    • RhoA-GDP regulates RhoB protein stability. Potential involvement of RhoGDIα
    • Ho TT, Merajver SD, Lapière CM, Nusgens BV, &, Deroanne CF, (2008) RhoA-GDP regulates RhoB protein stability. Potential involvement of RhoGDIα. J Biol Chem 283, 21588-21598.
    • (2008) J Biol Chem , vol.283 , pp. 21588-21598
    • Ho, T.T.1    Merajver, S.D.2    Lapière, C.M.3    Nusgens, B.V.4    Deroanne, C.F.5
  • 9
    • 79954609339 scopus 로고    scopus 로고
    • Clostridium botulinum C3 exoenzyme: Rho-inactivating tool in cell biology and a neurotrophic agent
    • Just I, Huelsenbeck SC, &, Genth H, (2010) Clostridium botulinum C3 exoenzyme: Rho-inactivating tool in cell biology and a neurotrophic agent. Open Toxinol J 3, 19-23.
    • (2010) Open Toxinol J , vol.3 , pp. 19-23
    • Just, I.1    Huelsenbeck, S.C.2    Genth, H.3
  • 10
    • 0025195876 scopus 로고
    • Microinjection of recombinant p21rho induces rapid changes in cell morphology
    • Paterson HF, Self AJ, Garrett MD, Just I, Aktories K, &, Hall A, (1990) Microinjection of recombinant p21rho induces rapid changes in cell morphology. J Cell Biol 111, 1001-1007.
    • (1990) J Cell Biol , vol.111 , pp. 1001-1007
    • Paterson, H.F.1    Self, A.J.2    Garrett, M.D.3    Just, I.4    Aktories, K.5    Hall, A.6
  • 14
    • 0031027205 scopus 로고    scopus 로고
    • Rho family GTPases and neuronal growth cone remodelling: Relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid
    • Kozma R, Sarner S, Ahmed S, &, Lim L, (1997) Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid. Mol Cell Biol 17, 1201-1211.
    • (1997) Mol Cell Biol , vol.17 , pp. 1201-1211
    • Kozma, R.1    Sarner, S.2    Ahmed, S.3    Lim, L.4
  • 15
    • 0030809301 scopus 로고    scopus 로고
    • Rac1 mediates collapsing-1-induced growth cone collapse
    • Jin Z, &, Strittmatter SM, (1997) Rac1 mediates collapsing-1-induced growth cone collapse. J Neurosci 17, 6256-6263.
    • (1997) J Neurosci , vol.17 , pp. 6256-6263
    • Jin, Z.1    Strittmatter, S.M.2
  • 16
    • 0025233512 scopus 로고
    • ADP-ribosylation of the rho/rac proteins induces growth inhibition, neurite outgrowth and acetylcholine esterase in cultured PC-12 cells
    • Nishiki T, Narumiya S, Morii N, Yamamot M, Fujiwara M, Kamata Y, Sakaguchi G, &, Kozaki S, (1990) ADP-ribosylation of the rho/rac proteins induces growth inhibition, neurite outgrowth and acetylcholine esterase in cultured PC-12 cells. Biochem Biophys Res Commun 167, 265-272.
    • (1990) Biochem Biophys Res Commun , vol.167 , pp. 265-272
    • Nishiki, T.1    Narumiya, S.2    Morii, N.3    Yamamot, M.4    Fujiwara, M.5    Kamata, Y.6    Sakaguchi, G.7    Kozaki, S.8
  • 17
    • 34247550969 scopus 로고    scopus 로고
    • RhoA signaling modulates cyclin D1 expression in human lung fibroblasts; Implications for idiopathic pulmonary fibrosis
    • Watts KL, Cottrell E, Hoban PR, &, Spiteri MA, (2006) RhoA signaling modulates cyclin D1 expression in human lung fibroblasts; implications for idiopathic pulmonary fibrosis. Respir Res 7, 88.
    • (2006) Respir Res , vol.7 , pp. 88
    • Watts, K.L.1    Cottrell, E.2    Hoban, P.R.3    Spiteri, M.A.4
  • 18
    • 0034739844 scopus 로고    scopus 로고
    • Dual stimulation of Ras/mitogen-activated protein kinase and RhoA by cell adhesion to fibronectin supports growth factor stimulated cell cycle progression
    • Danen EHJ, Sonnenveld P, Sonnenberg A, &, Yamada KM, (2000) Dual stimulation of Ras/mitogen-activated protein kinase and RhoA by cell adhesion to fibronectin supports growth factor stimulated cell cycle progression. J Cell Biol 151, 1413-1422.
    • (2000) J Cell Biol , vol.151 , pp. 1413-1422
    • Danen, E.H.J.1    Sonnenveld, P.2    Sonnenberg, A.3    Yamada, K.M.4
  • 19
    • 0031724471 scopus 로고    scopus 로고
    • P21WAF1/CIP1 is upregulated by the geranylgeranyltransferase i inhibitor GGTI-298 through a transforming growth factor β- And Sp1-responsive element: Involvement of the small GTPase RhoA
    • Adnane J, Bizouarn FA, Qian Y, Hamilton AD, &, Sebti SM, (1998) p21WAF1/CIP1 is upregulated by the geranylgeranyltransferase I inhibitor GGTI-298 through a transforming growth factor β- and Sp1-responsive element: involvement of the small GTPase RhoA. Mol Cell Biol 18, 6962-6970.
    • (1998) Mol Cell Biol , vol.18 , pp. 6962-6970
    • Adnane, J.1    Bizouarn, F.A.2    Qian, Y.3    Hamilton, A.D.4    Sebti, S.M.5
  • 21
    • 0000616906 scopus 로고    scopus 로고
    • Geranylgeranylated RhoB mediates inhibition of human tumor cell growth by farnesyltransferase inhibitors
    • Du W, &, Prendergast GC, (1999) Geranylgeranylated RhoB mediates inhibition of human tumor cell growth by farnesyltransferase inhibitors. Cancer Res 59, 5924-5928.
    • (1999) Cancer Res , vol.59 , pp. 5924-5928
    • Du, W.1    Prendergast, G.C.2
  • 22
    • 0034667370 scopus 로고    scopus 로고
    • RhoC GTPase, a novel transforming oncogene for human mammary epithelial cells that partially recapitulates the inflammatory breast cancer phenotype
    • van Golen KL, Wu ZF, Qiao XT, Bao LW, &, Marajver SD, (2000) RhoC GTPase, a novel transforming oncogene for human mammary epithelial cells that partially recapitulates the inflammatory breast cancer phenotype. Cancer Res 60, 5832-5838.
    • (2000) Cancer Res , vol.60 , pp. 5832-5838
    • Van Golen, K.L.1    Wu, Z.F.2    Qiao, X.T.3    Bao, L.W.4    Marajver, S.D.5
  • 23
    • 0029991647 scopus 로고    scopus 로고
    • Inactivation of the small GTP binding protein Rho induces multinucleate cell formation and apoptosis in murine T lymphoma EL4
    • Moorman JP, Bobak DA, &, Hahn CS, (1996) Inactivation of the small GTP binding protein Rho induces multinucleate cell formation and apoptosis in murine T lymphoma EL4. J Immunol 156, 4146-4153.
    • (1996) J Immunol , vol.156 , pp. 4146-4153
    • Moorman, J.P.1    Bobak, D.A.2    Hahn, C.S.3
  • 24
    • 0030730632 scopus 로고    scopus 로고
    • Inactivation of the small GTPase Rho disrupts cellular attachment and induces adhesion-dependent and adhesion-independent apoptosis
    • Bobak D, Moorman J, Guanzon A, Gilmer L, &, Hahn C, (1997) Inactivation of the small GTPase Rho disrupts cellular attachment and induces adhesion-dependent and adhesion-independent apoptosis. Oncogene 15, 2179-2189.
    • (1997) Oncogene , vol.15 , pp. 2179-2189
    • Bobak, D.1    Moorman, J.2    Guanzon, A.3    Gilmer, L.4    Hahn, C.5
  • 26
    • 33751178359 scopus 로고    scopus 로고
    • Enhanced serviva and regenration of axotomized retinal neurons by repeated delivery of cell-permeable C3-like Rho antagonists
    • Bertrand J, Di Polo A, &, McKerracher L, (2007) Enhanced serviva and regenration of axotomized retinal neurons by repeated delivery of cell-permeable C3-like Rho antagonists. Neurobiol Dis 25, 65-72.
    • (2007) Neurobiol Dis , vol.25 , pp. 65-72
    • Bertrand, J.1    Di Polo, A.2    McKerracher, L.3
  • 27
    • 0042171820 scopus 로고    scopus 로고
    • Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system
    • Dubreuil CI, Winton MJ, &, McKerracher L, (2003) Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system. J Cell Biol 162, 233-243.
    • (2003) J Cell Biol , vol.162 , pp. 233-243
    • Dubreuil, C.I.1    Winton, M.J.2    McKerracher, L.3
  • 29
    • 0041707712 scopus 로고    scopus 로고
    • Entrapment of Rho ADP-ribosylated by Clostridium botulinum C3 exoenzyme in the Rho-guanine nucleotide dissociation inhibitor-1 complex
    • Genth H, Gerhard R, Maeda A, Amano M, Kaibuchi K, Aktories K, &, Just I, (2003) Entrapment of Rho ADP-ribosylated by Clostridium botulinum C3 exoenzyme in the Rho-guanine nucleotide dissociation inhibitor-1 complex. J Biol Chem 278, 28523-28527.
    • (2003) J Biol Chem , vol.278 , pp. 28523-28527
    • Genth, H.1    Gerhard, R.2    Maeda, A.3    Amano, M.4    Kaibuchi, K.5    Aktories, K.6    Just, I.7
  • 30
    • 34247493760 scopus 로고    scopus 로고
    • Upregulation of the immediate early gene product RhoB by exoenzyme C3 from Clostridium limosum and toxin B from Clostridium difficile
    • Hülsenbeck J, Dreger SC, Gerhard R, Fritz G, Just I, &, Genth H, (2007) Upregulation of the immediate early gene product RhoB by exoenzyme C3 from Clostridium limosum and toxin B from Clostridium difficile. Biochemistry 46, 4923-4931.
    • (2007) Biochemistry , vol.46 , pp. 4923-4931
    • Hülsenbeck, J.1    Dreger, S.C.2    Gerhard, R.3    Fritz, G.4    Just, I.5    Genth, H.6
  • 31
    • 67449135261 scopus 로고    scopus 로고
    • Role of RHOB in the antiproliferative effect of glucocorticoid receptor on macrophage RAW264.7 cells
    • Wang X, Chen Y, Wang Y, Zhu X, Ma Y, Zhang S, &, Lu J, (2009) Role of RHOB in the antiproliferative effect of glucocorticoid receptor on macrophage RAW264.7 cells. J Endocrinol 200, 35-43.
    • (2009) J Endocrinol , vol.200 , pp. 35-43
    • Wang, X.1    Chen, Y.2    Wang, Y.3    Zhu, X.4    Ma, Y.5    Zhang, S.6    Lu, J.7
  • 32
    • 47749131192 scopus 로고    scopus 로고
    • Confluence-induced cell cycle exit involves pre-mitotic CDK inhibition by p27(Kip1) and cyclin D1 downregulation
    • Chassot AA, Lossaint G, Turchi L, Meneguzzi G, Fisher D, Ponzio G, &, Dulic V, (2008) Confluence-induced cell cycle exit involves pre-mitotic CDK inhibition by p27(Kip1) and cyclin D1 downregulation. Cell Cycle 7, 2038-2046.
    • (2008) Cell Cycle , vol.7 , pp. 2038-2046
    • Chassot, A.A.1    Lossaint, G.2    Turchi, L.3    Meneguzzi, G.4    Fisher, D.5    Ponzio, G.6    Dulic, V.7
  • 34
    • 0032498625 scopus 로고    scopus 로고
    • Apoptotic membrane blebbing is regulated by myosin light chain phosphorylation
    • Mills JC, Stone NL, Erhardt J, &, Pittman RN, (1998) Apoptotic membrane blebbing is regulated by myosin light chain phosphorylation. J Cell Biol 140, 627-636.
    • (1998) J Cell Biol , vol.140 , pp. 627-636
    • Mills, J.C.1    Stone, N.L.2    Erhardt, J.3    Pittman, R.N.4
  • 35
    • 0032557564 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells
    • Gerber HP, Dixit V, &, Ferrara N, (1998) Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells. J Biol Chem 273, 13313-13316.
    • (1998) J Biol Chem , vol.273 , pp. 13313-13316
    • Gerber, H.P.1    Dixit, V.2    Ferrara, N.3
  • 36
    • 0033001501 scopus 로고    scopus 로고
    • Cell cycle withdrawal promotes myogenic induction of Akt, a positive modulator of myocyte survival
    • Fujio Y, Guo K, Mano T, Mitsuuchi Y, Testa JR, &, Walsh K, (1999) Cell cycle withdrawal promotes myogenic induction of Akt, a positive modulator of myocyte survival. Mol Cell Biol 19, 5073-5082.
    • (1999) Mol Cell Biol , vol.19 , pp. 5073-5082
    • Fujio, Y.1    Guo, K.2    Mano, T.3    Mitsuuchi, Y.4    Testa, J.R.5    Walsh, K.6
  • 37
    • 59649085329 scopus 로고    scopus 로고
    • HT22 hippocampal neuronal cell line possesses functional cholinergic properties
    • Liu J, Li L, &, Suo WZ, (2009) HT22 hippocampal neuronal cell line possesses functional cholinergic properties. Life Sci 84, 267-271.
    • (2009) Life Sci , vol.84 , pp. 267-271
    • Liu, J.1    Li, L.2    Suo, W.Z.3
  • 38
    • 38849176224 scopus 로고    scopus 로고
    • Inhibition of the Rho/ROCK pathway reduces apoptosis during transplantation of embryonic stem cell-derived neural precursors
    • Koyanagi M, Takahashi J, Arakawa Y, Doi D, Fukuda H, Hayashi H, Narumiya S, &, Hashimoto N, (2008) Inhibition of the Rho/ROCK pathway reduces apoptosis during transplantation of embryonic stem cell-derived neural precursors. J Neurosci Res 86, 270-280.
    • (2008) J Neurosci Res , vol.86 , pp. 270-280
    • Koyanagi, M.1    Takahashi, J.2    Arakawa, Y.3    Doi, D.4    Fukuda, H.5    Hayashi, H.6    Narumiya, S.7    Hashimoto, N.8
  • 39
    • 16944366731 scopus 로고    scopus 로고
    • Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities
    • Donovan FM, Pike CJ, Cotman CW, &, Cunningham DD, (1997) Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities. J Neurosci 17, 5316-5326.
    • (1997) J Neurosci , vol.17 , pp. 5316-5326
    • Donovan, F.M.1    Pike, C.J.2    Cotman, C.W.3    Cunningham, D.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.