Bovine liver slices: A multifunctional in vitro model to study the prohormone dehydroepiandrosterone (DHEA)

Toxicology in Vitro

Volumn 26, Issue 6, 2012, Pages 1014-1021

  Rijk, Jeroen C W ^a   Bovee, Toine F H ^a   Peijnenburg, Ad A C M ^a   Groot, Maria J ^a   Rietjens, Ivonne M C M ^a   Nielen, Michel W F ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Bioactivation; Bioassay; Genomics; Liver slice; Mass spectrometry; Prohormone

Indexed keywords

17BETA TESTOSTERONE; 7 KETO DEHYDROEPIANDROSTERONE; 7ALPHA HYDROXYPRASTERONE; ANDROSTENEDIOL; ANDROSTENEDIONE; EPITESTOSTERONE; PRASTERONE; TESTOSTERONE DERIVATIVE; UNCLASSIFIED DRUG;

ANDROGENIC ACTIVITY; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; COW; DOWN REGULATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HORMONE ACTION; IN VITRO STUDY; LIVER SLICE; METABOLITE; NONHUMAN; UPREGULATION;

ANDROGENS; ANIMALS; BIOLOGICAL ASSAY; BIOTRANSFORMATION; CATTLE; DEHYDROEPIANDROSTERONE; GENE EXPRESSION PROFILING; LIVER; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; TESTOSTERONE; YEASTS;

BOVINAE;

EID: 84863813827     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2012.04.012     Document Type: Article

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