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Volumn 60, Issue 4, 2012, Pages 632-647

Hybrid proteins of Cobra Venom Factor and cobra C3: Tools to identify functionally important regions in Cobra Venom Factor

Author keywords

C3 convertase; Cobra (Naja sp.); Cobra Venom Factor; Complement; Complement component C3; Hybrid proteins

Indexed keywords

CLASSICAL COMPLEMENT PATHWAY C3 C5 CONVERTASE; COBROTOXIN; COMPLEMENT COMPONENT C3; HYBRID PROTEIN;

EID: 84863785107     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2012.05.004     Document Type: Article
Times cited : (8)

References (60)
  • 1
    • 0017254518 scopus 로고
    • Cobra venom factor: evidence for its being altered cobra C3 (the third component of complement)
    • Alper C.A., Balavitch D. Cobra venom factor: evidence for its being altered cobra C3 (the third component of complement). Science 1976, 191:1275-1276.
    • (1976) Science , vol.191 , pp. 1275-1276
    • Alper, C.A.1    Balavitch, D.2
  • 3
    • 0242589113 scopus 로고    scopus 로고
    • C3
    • Academic Press, New York, B.J. Morley, M.J. Walport (Eds.)
    • Botto M. C3. The Complement Facts Book 2000, 87-94. Academic Press, New York. B.J. Morley, M.J. Walport (Eds.).
    • (2000) The Complement Facts Book , pp. 87-94
    • Botto, M.1
  • 4
    • 0014823471 scopus 로고
    • Depletion of plasma complement in vivo by a protein of cobra venom: its effect on various immunologic reactions
    • Cochrane C.G., Müller-Eberhard H.J., Aikin B.S. Depletion of plasma complement in vivo by a protein of cobra venom: its effect on various immunologic reactions. J. Immunol. 1970, 105:55-69.
    • (1970) J. Immunol. , vol.105 , pp. 55-69
    • Cochrane, C.G.1    Müller-Eberhard, H.J.2    Aikin, B.S.3
  • 5
    • 0013141948 scopus 로고
    • Human complement component C3: cDNA coding sequence and derived primary structure
    • de Bruijn M.H., Fey G.H. Human complement component C3: cDNA coding sequence and derived primary structure. Proc. Natl. Acad. Sci. U.S.A. 1985, 82:708-712.
    • (1985) Proc. Natl. Acad. Sci. U.S.A. , vol.82 , pp. 708-712
    • de Bruijn, M.H.1    Fey, G.H.2
  • 6
    • 0021036761 scopus 로고
    • The activation of human complement component C5 by a fluid phase C5 convertase
    • DiScipio R.G., Smith C.A., Müller-Eberhard H.J., Hugli T.E. The activation of human complement component C5 by a fluid phase C5 convertase. J. Biol. Chem. 1983, 258:10629-10636.
    • (1983) J. Biol. Chem. , vol.258 , pp. 10629-10636
    • DiScipio, R.G.1    Smith, C.A.2    Müller-Eberhard, H.J.3    Hugli, T.E.4
  • 7
    • 0019365244 scopus 로고
    • Molecular characterization of the complement activating protein in the venom of the Indian cobra (Naja n. siamensis)
    • Eggertsen G., Lind P., Sjöquist J. Molecular characterization of the complement activating protein in the venom of the Indian cobra (Naja n. siamensis). Mol. Immunol. 1981, 18:125-133.
    • (1981) Mol. Immunol. , vol.18 , pp. 125-133
    • Eggertsen, G.1    Lind, P.2    Sjöquist, J.3
  • 8
    • 0020607483 scopus 로고
    • Antigenic relationships between human and cobra complement factors C3 and cobra venom factor (CVF) from the Indian cobra (Naja naja)
    • Eggertsen G., Lundwall A., Hellman U., Sjöquist J. Antigenic relationships between human and cobra complement factors C3 and cobra venom factor (CVF) from the Indian cobra (Naja naja). J. Immunol. 1983, 131:1920-1923.
    • (1983) J. Immunol. , vol.131 , pp. 1920-1923
    • Eggertsen, G.1    Lundwall, A.2    Hellman, U.3    Sjöquist, J.4
  • 9
    • 78650638514 scopus 로고    scopus 로고
    • Structures of C3b in complex with factors B and D give insight into complement convertase formation
    • Forneris F., Ricklin D., Wu J., Tzekou A., Wallace R.S., Lambris J.D., Gros P. Structures of C3b in complex with factors B and D give insight into complement convertase formation. Science 2010, 330:1816-1820.
    • (2010) Science , vol.330 , pp. 1816-1820
    • Forneris, F.1    Ricklin, D.2    Wu, J.3    Tzekou, A.4    Wallace, R.S.5    Lambris, J.D.6    Gros, P.7
  • 11
  • 12
    • 0029146624 scopus 로고
    • Molecular cloning and derived primary structure of cobra venom factor
    • Correction
    • Fritzinger D.C., Bredehorst R., Vogel C.-W. Molecular cloning and derived primary structure of cobra venom factor. Proc. Natl. Acad. Sci. U.S.A. 1995, 92:7605. Correction.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 7605
    • Fritzinger, D.C.1    Bredehorst, R.2    Vogel, C.-W.3
  • 13
    • 77957927505 scopus 로고    scopus 로고
    • A novel concept for the treatment of paroxysmal nocturnal haemoglobinuria (PNH): complement depletion with a human C3 derivative with cobra venom factor-like activity prevents lysis of PNH erythrocytes
    • Fritzinger D.C., Ferreira V.P., Hew B.E., St.John W., Pangburn M.K., Vogel C.-W. A novel concept for the treatment of paroxysmal nocturnal haemoglobinuria (PNH): complement depletion with a human C3 derivative with cobra venom factor-like activity prevents lysis of PNH erythrocytes. Mol. Immunol. 2008, 45:4177.
    • (2008) Mol. Immunol. , vol.45 , pp. 4177
    • Fritzinger, D.C.1    Ferreira, V.P.2    Hew, B.E.3    St John, W.4    Pangburn, M.K.5    Vogel, C.-W.6
  • 18
    • 0015124635 scopus 로고
    • The C3-activator system: an alternate pathway of complement activation
    • Götze O., Müller-Eberhard H.J. The C3-activator system: an alternate pathway of complement activation. J. Exp. Med. 1971, 134:90s-108s.
    • (1971) J. Exp. Med. , vol.134
    • Götze, O.1    Müller-Eberhard, H.J.2
  • 20
    • 77957916421 scopus 로고    scopus 로고
    • Cobra complement factor B: evidence for additional function as CVF-inhibitor
    • Grunwald T., Bredehorst R., Vogel C.-W. Cobra complement factor B: evidence for additional function as CVF-inhibitor. Mol. Immunol. 1996, 33:14.
    • (1996) Mol. Immunol. , vol.33 , pp. 14
    • Grunwald, T.1    Bredehorst, R.2    Vogel, C.-W.3
  • 21
    • 0023029239 scopus 로고
    • The effects of metal ions and temperature on the interaction of cobra venom factor and human complement factor B
    • Hensley P., O'Keefe M.C., Spangler C.J., Osborne J.C., Vogel C.-W. The effects of metal ions and temperature on the interaction of cobra venom factor and human complement factor B. J. Biol. Chem. 1986, 261:11038-11044.
    • (1986) J. Biol. Chem. , vol.261 , pp. 11038-11044
    • Hensley, P.1    O'Keefe, M.C.2    Spangler, C.J.3    Osborne, J.C.4    Vogel, C.-W.5
  • 22
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho S.N., Hunt H.D., Horton R.M., Pullen J.K., Pease L.R. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 1989, 77:51-59.
    • (1989) Gene , vol.77 , pp. 51-59
    • Ho, S.N.1    Hunt, H.D.2    Horton, R.M.3    Pullen, J.K.4    Pease, L.R.5
  • 23
    • 84863778086 scopus 로고    scopus 로고
    • Complement depletion with humanized cobra venom factor (CVF) improves the severity of experimental autoimmune myasthenia gravis (EAMG)
    • Huda R., Fritzinger D.C., Finnegan P.F., Christadoss P., Vogel C.-W. Complement depletion with humanized cobra venom factor (CVF) improves the severity of experimental autoimmune myasthenia gravis (EAMG). Mol. Immunol. 2011, 48:1712.
    • (2011) Mol. Immunol. , vol.48 , pp. 1712
    • Huda, R.1    Fritzinger, D.C.2    Finnegan, P.F.3    Christadoss, P.4    Vogel, C.-W.5
  • 25
    • 33750859976 scopus 로고    scopus 로고
    • Structure of C3b reveals conformational changes that underlie complement activity
    • Janssen B.J., Christodoulidou A., McCarthy A., Lambris J.D., Gros P. Structure of C3b reveals conformational changes that underlie complement activity. Nature 2006, 444:213-216.
    • (2006) Nature , vol.444 , pp. 213-216
    • Janssen, B.J.1    Christodoulidou, A.2    McCarthy, A.3    Lambris, J.D.4    Gros, P.5
  • 26
    • 69249220131 scopus 로고    scopus 로고
    • Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex
    • Janssen B.J., Gomes L., Koning R.I., Svergun D.I., Koster A.J., Fritzinger D.C., Vogel C.-W., Gros P. Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex. EMBO J. 2009, 28:2469-2478.
    • (2009) EMBO J. , vol.28 , pp. 2469-2478
    • Janssen, B.J.1    Gomes, L.2    Koning, R.I.3    Svergun, D.I.4    Koster, A.J.5    Fritzinger, D.C.6    Vogel, C.-W.7    Gros, P.8
  • 29
    • 64049115651 scopus 로고    scopus 로고
    • The crystal structure of cobra venom factor, a cofactor for C3- and C5-convertase CVFBb
    • Krishnan V., Ponnuraj K., Xu Y., Macon K., Volanakis J.E., Narayana S.V. The crystal structure of cobra venom factor, a cofactor for C3- and C5-convertase CVFBb. Structure 2009, 17:611-619.
    • (2009) Structure , vol.17 , pp. 611-619
    • Krishnan, V.1    Ponnuraj, K.2    Xu, Y.3    Macon, K.4    Volanakis, J.E.5    Narayana, S.V.6
  • 30
    • 0016705591 scopus 로고
    • The influence of C3b inactivator (KAF) concentration on the abilityof serum to support complement activation
    • Lachmann P.J., Halbwachs L. The influence of C3b inactivator (KAF) concentration on the abilityof serum to support complement activation. Clin. Exp. Immunol. 1975, 21:109-114.
    • (1975) Clin. Exp. Immunol. , vol.21 , pp. 109-114
    • Lachmann, P.J.1    Halbwachs, L.2
  • 32
    • 0018426978 scopus 로고
    • The alternative pathway C3/C5 convertase: chemical basis of factor B activation
    • Lesavre P.H., Hugli T.E., Esser A.F., Müller-Eberhard H.J. The alternative pathway C3/C5 convertase: chemical basis of factor B activation. J. Immunol. 1979, 123:529-534.
    • (1979) J. Immunol. , vol.123 , pp. 529-534
    • Lesavre, P.H.1    Hugli, T.E.2    Esser, A.F.3    Müller-Eberhard, H.J.4
  • 33
    • 0021247927 scopus 로고
    • Chemical characterization of cyanogen bromide fragments from the β-chain of human complement factor C3
    • Lundwall Å., Hellman U., Eggertsen G., Sjöquist J. Chemical characterization of cyanogen bromide fragments from the β-chain of human complement factor C3. FEBS Lett. 1984, 169:57-62.
    • (1984) FEBS Lett. , vol.169 , pp. 57-62
    • Lundwall, Å.1    Hellman, U.2    Eggertsen, G.3    Sjöquist, J.4
  • 34
    • 0017199672 scopus 로고
    • Alternative pathway of complement: recruitment of precursor properdin by the labile C3/C5 convertase and the potentiation of the pathway
    • Medicus R.G., Götze O., Müller-Eberhard H.J. Alternative pathway of complement: recruitment of precursor properdin by the labile C3/C5 convertase and the potentiation of the pathway. J. Exp. Med. 1976, 144:1076-1093.
    • (1976) J. Exp. Med. , vol.144 , pp. 1076-1093
    • Medicus, R.G.1    Götze, O.2    Müller-Eberhard, H.J.3
  • 36
    • 0024205864 scopus 로고
    • A novel cleavage product of human complement component C3 with structural and functional properties of cobra venom factor
    • O'Keefe M.C., Caporale L.H., Vogel C.-W. A novel cleavage product of human complement component C3 with structural and functional properties of cobra venom factor. J. Biol. Chem. 1988, 263:12690-12697.
    • (1988) J. Biol. Chem. , vol.263 , pp. 12690-12697
    • O'Keefe, M.C.1    Caporale, L.H.2    Vogel, C.-W.3
  • 37
    • 0022521480 scopus 로고
    • The C3 convertase of the alternative pathway of human complement. Enzymic properties of the bimolecular proteinase
    • Pangburn M.K., Müller-Eberhard H.J. The C3 convertase of the alternative pathway of human complement. Enzymic properties of the bimolecular proteinase. Biochem. J. 1986, 235:723-730.
    • (1986) Biochem. J. , vol.235 , pp. 723-730
    • Pangburn, M.K.1    Müller-Eberhard, H.J.2
  • 38
    • 0017704496 scopus 로고
    • Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein β1H for cleavage of C3b and C4b in solution
    • Pangburn M.K., Schreiber R.D., Müller-Eberhard H.J. Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein β1H for cleavage of C3b and C4b in solution. J. Exp. Med. 1977, 146:257-269.
    • (1977) J. Exp. Med. , vol.146 , pp. 257-269
    • Pangburn, M.K.1    Schreiber, R.D.2    Müller-Eberhard, H.J.3
  • 39
    • 0023629210 scopus 로고
    • Antibody conjugates with cobra venom factor. Synthesis and biochemical characterization
    • Petrella E.C., Wilkie S.D., Smith C.A., Morgan A.C., Vogel C.-W. Antibody conjugates with cobra venom factor. Synthesis and biochemical characterization. J. Immunol. Methods 1987, 104:159-172.
    • (1987) J. Immunol. Methods , vol.104 , pp. 159-172
    • Petrella, E.C.1    Wilkie, S.D.2    Smith, C.A.3    Morgan, A.C.4    Vogel, C.-W.5
  • 40
    • 0014472175 scopus 로고
    • Passive hemolysis by serum and cobra venom factor: a new mechanism inducing membrane damage by complement
    • Pickering R.J., Wolfson M.R., Good R.A., Gewurz H. Passive hemolysis by serum and cobra venom factor: a new mechanism inducing membrane damage by complement. Proc. Natl. Acad. Sci. U.S.A. 1969, 62:521-527.
    • (1969) Proc. Natl. Acad. Sci. U.S.A. , vol.62 , pp. 521-527
    • Pickering, R.J.1    Wolfson, M.R.2    Good, R.A.3    Gewurz, H.4
  • 41
    • 0032479161 scopus 로고    scopus 로고
    • C5 convertase of the alternative pathway of complement. Kinetic analysis of the free and surface-bound forms of the enzyme
    • Rawal N., Pangburn M.K. C5 convertase of the alternative pathway of complement. Kinetic analysis of the free and surface-bound forms of the enzyme. J. Biol. Chem. 1998, 273:16828-16835.
    • (1998) J. Biol. Chem. , vol.273 , pp. 16828-16835
    • Rawal, N.1    Pangburn, M.K.2
  • 42
    • 0034141908 scopus 로고    scopus 로고
    • Functional role of the noncatalytic subunit of complement C5 convertase
    • Rawal N., Pangburn M.K. Functional role of the noncatalytic subunit of complement C5 convertase. J. Immunol. 2000, 164:1379-1385.
    • (2000) J. Immunol. , vol.164 , pp. 1379-1385
    • Rawal, N.1    Pangburn, M.K.2
  • 43
    • 0035094142 scopus 로고    scopus 로고
    • Structure/function of C5 convertases of complement
    • Rawal N., Pangburn M.K. Structure/function of C5 convertases of complement. Int. Immunopharmacol 2001, 1:415-422.
    • (2001) Int. Immunopharmacol , vol.1 , pp. 415-422
    • Rawal, N.1    Pangburn, M.K.2
  • 44
    • 0020381942 scopus 로고
    • Ultrastructure of cobra venom factor-dependent C3/C5 convertase and its zymogen, factor B of human complement
    • Smith C.A., Vogel C.-W., Muller-Eberhard H.J. Ultrastructure of cobra venom factor-dependent C3/C5 convertase and its zymogen, factor B of human complement. J. Biol. Chem. 1982, 257:9879-9882.
    • (1982) J. Biol. Chem. , vol.257 , pp. 9879-9882
    • Smith, C.A.1    Vogel, C.-W.2    Muller-Eberhard, H.J.3
  • 45
    • 0021351421 scopus 로고
    • MHC Class III products: an electron microscopic study of the C3 convertases of human complement
    • Smith C.A., Vogel C.-W., Müller-Eberhard H.J. MHC Class III products: an electron microscopic study of the C3 convertases of human complement. J. Exp. Med. 1984, 159:324-329.
    • (1984) J. Exp. Med. , vol.159 , pp. 324-329
    • Smith, C.A.1    Vogel, C.-W.2    Müller-Eberhard, H.J.3
  • 47
    • 0345735840 scopus 로고    scopus 로고
    • Expression and characterization of the C345C/NTR domains of complement components C3 and C5
    • Thai C.T., Ogata R.T. Expression and characterization of the C345C/NTR domains of complement components C3 and C5. J. Immunol. 2003, 171:6565-6573.
    • (2003) J. Immunol. , vol.171 , pp. 6565-6573
    • Thai, C.T.1    Ogata, R.T.2
  • 48
    • 38449097109 scopus 로고    scopus 로고
    • Humanized cobra venom factor: experimental therapeutics for targeted complement activation and complement depletion
    • Vogel C.-W., Fritzinger D.C. Humanized cobra venom factor: experimental therapeutics for targeted complement activation and complement depletion. Curr. Pharm. Des. 2007, 13:2916-2926.
    • (2007) Curr. Pharm. Des. , vol.13 , pp. 2916-2926
    • Vogel, C.-W.1    Fritzinger, D.C.2
  • 49
    • 77957916119 scopus 로고    scopus 로고
    • Cobra venom factor: structure, function, and humanization for therapeutic complement depletion
    • Vogel C.-W., Fritzinger D.C. Cobra venom factor: structure, function, and humanization for therapeutic complement depletion. Toxicon 2010, 56:1198-1222.
    • (2010) Toxicon , vol.56 , pp. 1198-1222
    • Vogel, C.-W.1    Fritzinger, D.C.2
  • 50
    • 0020354908 scopus 로고
    • The cobra venom factor-dependent C3 convertase of human complement. A kinetic and thermodynamic analysis of a protease acting on its natural high molecular weight substrate
    • Vogel C.-W., Müller-Eberhard H.J. The cobra venom factor-dependent C3 convertase of human complement. A kinetic and thermodynamic analysis of a protease acting on its natural high molecular weight substrate. J. Biol. Chem. 1982, 257:8292-8299.
    • (1982) J. Biol. Chem. , vol.257 , pp. 8292-8299
    • Vogel, C.-W.1    Müller-Eberhard, H.J.2
  • 51
    • 0021123192 scopus 로고
    • Cobra venom factor: improved method for purification and biochemical characterization
    • Vogel C.-W., Müller-Eberhard H.J. Cobra venom factor: improved method for purification and biochemical characterization. J. Immunol. Methods 1984, 73:203-220.
    • (1984) J. Immunol. Methods , vol.73 , pp. 203-220
    • Vogel, C.-W.1    Müller-Eberhard, H.J.2
  • 52
    • 0021707488 scopus 로고
    • Cobra venom factor: structural homology with the third component of human complement
    • Vogel C.-W., Smith C.A., Müller-Eberhard H.J. Cobra venom factor: structural homology with the third component of human complement. J. Immunol. 1984, 133:3235-3241.
    • (1984) J. Immunol. , vol.133 , pp. 3235-3241
    • Vogel, C.-W.1    Smith, C.A.2    Müller-Eberhard, H.J.3
  • 55
    • 85053991605 scopus 로고
    • Cobra venom factor, the complement-activating protein of cobra venom
    • Marcel Dekker, New York
    • Vogel C.-W. Cobra venom factor, the complement-activating protein of cobra venom. Handbook of Natural Toxins: Reptile and Amphibian Venoms 1991, vol. 5:p147-188. Marcel Dekker, New York.
    • (1991) Handbook of Natural Toxins: Reptile and Amphibian Venoms , vol.5
    • Vogel, C.-W.1
  • 56
    • 0015992854 scopus 로고
    • Alternative pathway for the activation of complement in human serum. Formation and composition of the complex with cobra venom factor that cleaves the third component of complement
    • Vogt W., Dieminger L., Lynen R., Schmidt G. Alternative pathway for the activation of complement in human serum. Formation and composition of the complex with cobra venom factor that cleaves the third component of complement. Hoppe Seyler's Z. Physiol. Chem. 1974, 355:171-183.
    • (1974) Hoppe Seyler's Z. Physiol. Chem. , vol.355 , pp. 171-183
    • Vogt, W.1    Dieminger, L.2    Lynen, R.3    Schmidt, G.4
  • 57
    • 0017874834 scopus 로고
    • A new function of the activated third component of complement: binding to C5, an essential step for C5 activation
    • Vogt W., Schmidt G., von Buttlar B., Dieminger L. A new function of the activated third component of complement: binding to C5, an essential step for C5 activation. Immunology 1978, 34:29-40.
    • (1978) Immunology , vol.34 , pp. 29-40
    • Vogt, W.1    Schmidt, G.2    von Buttlar, B.3    Dieminger, L.4
  • 58
    • 0019174398 scopus 로고
    • Comparison of Naja n. naja and Naja h. haje cobra-venom factors: correlation between binding affinity for the fifth component of complement and mediation of its cleavage
    • von Zabern I., Hinsch B., Przyklenk H., Schmidt G., Vogt W. Comparison of Naja n. naja and Naja h. haje cobra-venom factors: correlation between binding affinity for the fifth component of complement and mediation of its cleavage. Immunobiology 1980, 157:499-514.
    • (1980) Immunobiology , vol.157 , pp. 499-514
    • von Zabern, I.1    Hinsch, B.2    Przyklenk, H.3    Schmidt, G.4    Vogt, W.5
  • 59
    • 73949123455 scopus 로고    scopus 로고
    • Depletion of the C3 component of complement enhances the ability of rituximab-coated target cells to activate human NK cells and improves the efficacy of monoclonal antibody therapy in an in vivo model
    • Wang S.Y., Veeramani S., Racila E., Cagley J., Fritzinger D., Vogel C.-W., St John W., Weiner G.J. Depletion of the C3 component of complement enhances the ability of rituximab-coated target cells to activate human NK cells and improves the efficacy of monoclonal antibody therapy in an in vivo model. Blood 2009, 114:5322-5330.
    • (2009) Blood , vol.114 , pp. 5322-5330
    • Wang, S.Y.1    Veeramani, S.2    Racila, E.3    Cagley, J.4    Fritzinger, D.5    Vogel, C.-W.6    St John, W.7    Weiner, G.J.8
  • 60
    • 0017139872 scopus 로고
    • Modulation of the alternative complement pathways by beta1H globulin
    • Whaley K., Ruddy S. Modulation of the alternative complement pathways by beta1H globulin. J. Exp. Med. 1976, 144:1147-1163.
    • (1976) J. Exp. Med. , vol.144 , pp. 1147-1163
    • Whaley, K.1    Ruddy, S.2


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