Pneumococcal nasopharyngeal carriage following reduced doses of a 7-valent pneumococcal conjugate vaccine and a 23-valent pneumococcal polysaccharide vaccine booster

Clinical and Vaccine Immunology

Volumn 17, Issue 12, 2010, Pages 1970-1976

  Russell, F M ^a   Carapetis, J R ^b   Satzke, C ^a,c   Tikoduadua, L ^d   Waqatakirewa, L ^d   Chandra, R ^d   Seduadua, A ^d   Oftadeh, S ^e   Cheung, Y B ^f,g   Gilbert, G L ^e   Mulholland, E K ^b,h  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MENZIES SCHOOL OF HEALTH RESEARCH   (Australia)

^c MURDOCH CHILDREN'S RESEARCH INSTITUTE   (Australia)

^d Ministry of Health   (Fiji)

^e Institute of Clinical Pathology and Medical Research NSW Health Pathology   (Australia)

^f SINGAPORE CLINICAL RESEARCH INSTITUTE   (Singapore)

^g DUKE NUS MEDICAL SCHOOL   (Singapore)

^h LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PNEUMOCOCCUS VACCINE;

ARTICLE; BACTERIUM ISOLATE; DOSE RESPONSE; DRUG DOSE REDUCTION; DRUG EFFECT; FEMALE; HUMAN; HUMAN TISSUE; INFANT; MAJOR CLINICAL STUDY; MALE; MULTIPLEX POLYMERASE CHAIN REACTION; NOSE SMEAR; PNEUMOCOCCAL INFECTION; PRIORITY JOURNAL; SINGLE DRUG DOSE; STREPTOCOCCUS PNEUMONIAE; VACCINATION;

CARRIER STATE; FEMALE; FIJI; HUMANS; IMMUNIZATION, SECONDARY; INFANT; MALE; NASOPHARYNX; PNEUMOCOCCAL INFECTIONS; PNEUMOCOCCAL VACCINES; STREPTOCOCCUS PNEUMONIAE; VACCINATION;

EID: 78649890471     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00117-10     Document Type: Article

References (46)

1. Reference deleted.
2. Cheung, Y. B., S. M. Zaman, E. D. Nsekpong, C. A. Van Beneden, R. A. Adegbola, B. Greenwood, and F. T. Cutts. 2009. Nasopharyngeal carriage of Streptococcus pneumoniae in Gambian children who participated in a 9-valent pneumococcal conjugate vaccine trial and in their younger siblings. Pediatr. Infect. Dis. J. 28:990-995.
3. Christensen, P., B. Hovelius, K. Prellner, C. Rosen, K. K. Christensen, D. N. Kurl, L. Larsson, A. Stjernquist-Desatnik, and C. Schalen. 1985. Effects of pneumococcal vaccination on tonsillo-pharyngitis and upper respiratory tract flora. Int. Arch. Allergy Appl. Immunol. 78:161-166.
4. Cohen, R., C. Levy, F. de La Rocque, N. Gelbert, A. Wollner, B. Fritzell, E. Bonnet, R. Tetelboum, and E. Varon. 2006. Impact of pneumococcal conjugate vaccine and of reduction of antibiotic use on nasopharyngeal carriage of nonsusceptible pneumococci in children with acute otitis media. Pediatr. Infect. Dis. J. 25:1001-1007.
5. Dagan, R., N. Givon-Lavi, O. Zamir, M. Sikuler-Cohen, L. Guy, J. Janco, P. Yagupsky, and D. Fraser. 2002. Reduction of nasopharyngeal carriage of Streptococcus pneumoniae after administration of a 9-valent pneumococcal conjugate vaccine to toddlers attending day care centers. J. Infect. Dis. 185:927-936.
6. Dagan, R., R. Melamed, M. Muallem, L. Piglansky, D. Greenberg, O. Abramson, P. M. Mendelman, N. Bohidar, and P. Yagupsky. 1996. Reduction of nasopharyngeal carriage of pneumococci during the second year of life by a heptavalent conjugate pneumococcal vaccine. J. Infect. Dis. 174:1271-1278.
7. Douglas, R. M., D. Hansman, H. B. Miles, and J. C. Paton. 1986. Pneumococcal carriage and type-specific antibody. Failure of a 14-valent vaccine to reduce carriage in healthy children. Am. J. Dis. Child. 140:1183-1185.
8. Dunais, B., P. Bruno, H. Carsenti-Dellamonica, P. Touboul, P. Dellamonica, and C. Pradier. 2008. Trends in nasopharyngeal carriage of Streptococcus pneumoniae among children attending daycare centers in southeastern France from 1999 to 2006. Pediatr. Infect. Dis. J. 27:1033-1035.
9. Flannery, B., R. T. Heffernan, L. H. Harrison, S. M. Ray, A. L. Reingold, J. Hadler, W. Schaffner, R. Lynfield, A. R. Thomas, J. Li, M. Campsmith, C. G. Whitney, and A. Schuchat. 2006. Changes in invasive pneumococcal disease among HIV-infected adults living in the era of childhood pneumococcal immunization. Ann. Intern. Med. 144:1-9.
10. Frazao, N., A. Brito-Avo, C. Simas, J. Saldanha, R. Mato, S. Nunes, N. G. Sousa, J. A. Carrico, J. S. Almeida, I. Santos-Sanches, and H. de Lencastre. 2005. Effect of the seven-valent conjugate pneumococcal vaccine on carriage and drug resistance of Streptococcus pneumoniae in healthy children attending day-care centers in Lisbon. Pediatr. Infect. Dis. J. 24:243-252.
11. Ghaffar, F., T. Barton, J. Lozano, L. S. Muniz, P. Hicks, V. Gan, N. Ahmad, and G. H. McCracken, Jr. 2004. Effect of the 7-valent pneumococcal conjugate vaccine on nasopharyngeal colonization by Streptococcus pneumoniae in the first 2 years of life. Clin. Infect. Dis. 39:930-938.
12. Hammitt, L. L., D. L. Bruden, J. C. Butler, H. C. Baggett, D. A. Hurlburt, A. Reasonover, and T. W. Hennessy. 2006. Indirect effect of conjugate vaccine on adult carriage of Streptococcus pneumoniae: an explanation of trends in invasive pneumococcal disease. J. Infect. Dis. 193:1487-1494.
13. Heath, P. T., and J. McVernon. 2002. The UK Hib vaccine experience. Arch. Dis. Child. 86:396-399.
14. Herva, E., J. Luotonen, M. Timonen, M. Sibakov, P. Karma, and P. H. Makela. 1980. The effect of polyvalent pneumococcal polysaccharide vaccine on nasopharyngeal and nasal carriage of Streptococcus pneumoniae. Scand. J. Infect. Dis. 12:97-100.
15. Huang, S. S., R. Platt, S. L. Rifas-Shiman, S. I. Pelton, D. Goldmann, and J. A. Finkelstein. 2005. Post-PCV7 changes in colonizing pneumococcal serotypes in 16 Massachusetts communities, 2001 and 2004. Pediatrics 116:e408-e413.
16. Jin, P., F. Kong, M. Xiao, S. Oftadeh, F. Zhou, C. Liu, F. Russell, and G. L. Gilbert. 2009. First report of putative Streptococcus pneumoniae serotype 6D among nasopharyngeal isolates from Fijian children. J. Infect. Dis. 200:1375-1380.
17. Jones, V. F., C. Harrison, G. G. Stout, and J. Hopkins. 2005. Nasopharyngeal colonization with heptavalent pneumococcal conjugate vaccine serotypes of Streptococcus pneumoniae with prolonged vaccine dosing intervals. Pediatr. Infect. Dis. J. 24:969-973.
18. Kellner, J. D., D. Scheifele, O. G. Vanderkooi, J. Macdonald, D. L. Church, and G. J. Tyrrell. 2008. Effects of routine infant vaccination with the 7-valent pneumococcal conjugate vaccine on nasopharyngeal colonization with Streptococcus pneumoniae in children in Calgary, Canada. Pediatr. Infect. Dis. J. 27:526-532.
19. Kelly, D. F., E. R. Moxon, and A. J. Pollard. 2004. Haemophilus influenzae type b conjugate vaccines. Immunology 113:163-174.
20. Kong, F., M. Brown, A. Sabananthan, X. Zeng, and G. L. Gilbert. 2006. Multiplex PCR-based reverse line blot hybridization assay to identify 23 Streptococcus pneumoniae polysaccharide vaccine serotypes. J. Clin. Microbiol. 44:1887-1891.
21. Lakshman, R., C. Murdoch, G. Race, R. Burkinshaw, L. Shaw, and A. Finn. 2003. Pneumococcal nasopharyngeal carriage in children following heptavalent pneumococcal conjugate vaccination in infancy. Arch. Dis. Child. 88:211-214.
22. Lipsitch, M., K. O'Neill, D. Cordy, B. Bugalter, K. Trzcinski, C. M. Thompson, R. Goldstein, S. Pelton, H. Huot, V. Bouchet, R. Reid, M. Santosham, and K. L. O'Brien. 2007. Strain characteristics of Streptococcus pneumoniae carriage and invasive disease isolates during a cluster-randomized clinical trial of the 7-valent pneumococcal conjugate vaccine. J. Infect. Dis. 196:1221-1227.
23. Madhi, S., P. Adrian, L. Kuwanda, C. Cutland, W. Albrich, and K. Klugman. 2007. Long-term effect of pneumococcal conjugate vaccine on nasopharyngeal colonization by Streptococcus pneumoniae and associated interactions with Staphylococcus aureus and Haemophilus influenzae colonization on HIV-infected and HIV-uninfected children. J. Infect. Dis. 196:1662-1666.
24. Mbelle, N., R. E. Huebner, A. D. Wasas, A. Kimura, I. Chang, and K. P. Klugman. 1999. Immunogenicity and impact on nasopharyngeal carriage of a nonavalent pneumococcal conjugate vaccine. J. Infect. Dis. 180:1171-1176.
25. Millar, E. V., K. L. O'Brien, J. P. Watt, M. A. Bronsdon, J. Dallas, C. G. Whitney, R. Reid, and M. Santosham. 2006. Effect of community-wide conjugate pneumococcal vaccine use in infancy on nasopharyngeal carriage through 3 years of age: a cross-sectional study in a high-risk population. Clin. Infect. Dis. 43:8-15.
26. Millar, E. V., J. P. Watt, M. A. Bronsdon, J. Dallas, R. Reid, M. Santosham, and K. L. O'Brien. 2008. Indirect effect of 7-valent pneumococcal conjugate vaccine on pneumococcal colonization among unvaccinated household members. Clin. Infect. Dis. 47:989-996.
27. Moore, M. R., T. B. Hyde, T. W. Hennessy, D. J. Parks, A. L. Reasonover, M. Harker-Jones, J. Gove, D. L. Bruden, K. Rudolph, A. Parkinson, J. C. Butler, and A. Schuchat. 2004. Impact of a conjugate vaccine on community-wide carriage of nonsusceptible Streptococcus pneumoniae in Alaska. J. Infect. Dis. 190:2031-2038.
28. Obaro, S. K., R. A. Adegbola, W. A. Banya, and B. M. Greenwood. 1996. Carriage of pneumococci after pneumococcal vaccination. Lancet 348:271-272.
29. O'Brien, K. L., M. A. Bronsdon, R. Dagan, P. Yagupsky, J. Janco, J. Elliott, C. G. Whitney, Y. H. Yang, L. G. Robinson, B. Schwartz, and G. M. Carlone. 2001. Evaluation of a medium (STGG) for transport and optimal recovery of Streptococcus pneumoniae from nasopharyngeal secretions collected during field studies. J. Clin. Microbiol. 39:1021-1024.
30. O'Brien, K. L., and H. Nohynek. 2003. Report from a WHO working group: standard method for detecting upper respiratory carriage of Streptococcus pneumoniae. Pediatr. Infect. Dis. J. 22:133-140.
31. O'Brien, K. L., L. J. Wolfson, J. P. Watt, E. Henkle, M. Deloria-Knoll, N. McCall, E. Lee, K. Mulholland, O. S. Levine, and T. Cherian. 2009. Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates. Lancet 374:893-902.
32. Park, I. H., D. G. Pritchard, R. Cartee, A. Brandao, M. C. Brandileone, and M. H. Nahm. 2007. Discovery of a new capsular serotype (6C) within serogroup 6 of Streptococcus pneumoniae. J. Clin. Microbiol. 45:1225-1233.
33. Pelton, S. I., H. Huot, J. A. Finkelstein, C. J. Bishop, K. K. Hsu, J. Kellenberg, S. S. Huang, R. Goldstein, and W. P. Hanage. 2007. Emergence of 19A as virulent and multidrug resistant pneumococcus in Massachusetts following universal immunization of infants with pneumococcal conjugate vaccine. Pediatr. Infect. Dis. J. 26:468-472.
34. Pelton, S. I., A. M. Loughlin, and C. D. Marchant. 2004. Seven valent pneumococcal conjugate vaccine immunization in two Boston communities: changes in serotypes and antimicrobial susceptibility among Streptococcus pneumoniae isolates. Pediatr. Infect. Dis. J. 23:1015-1022.
35. Rosen, C., P. Christensen, J. Henrichsen, B. Hovelius, and K. Prellner. 1984. Beneficial effect of pneumococcal vaccination on otitis media in children over two years old. Int. J. Pediatr. Otorhinolaryngol. 7:239-246.
36. Russell, F. M., A. Balloch, M. L. Tang, J. R. Carapetis, P. Licciardi, J. Nelson, A. W. Jenney, L. Tikoduadua, L. Waqatakirewa, J. Pryor, G. B. Byrnes, Y. B. Cheung, and E. K. Mulholland. 2009. Immunogenicity following one, two, or three doses of the 7-valent pneumococcal conjugate vaccine. Vaccine 27:5685-5691.
37. Russell, F. M., S. S. Biribo, G. Selvaraj, F. Oppedisano, S. Warren, A. Seduadua, E. K. Mulholland, and J. R. Carapetis. 2006. As a bacterial culture medium, citrated sheep blood agar is a practical alternative to citrated human blood agar in laboratories of developing countries. J. Clin. Microbiol. 44:3346-3351.
38. Russell, F. M., J. R. Carapetis, A. Balloch, P. V. Licciardi, A. W. Jenney, L. Tikoduadua, L. Waqatakirewa, J. Pryor, J. Nelson, G. B. Byrnes, Y. B. Cheung, M. L. Tang, and E. K. Mulholland. 2010. Hyporesponsiveness to re-challenge dose following pneumococcal polysaccharide vaccine at 12 months of age, a randomized controlled trial. Vaccine 28:3341-3349.
39. Russell, F. M., P. V. Licciardi, A. Balloch, V. Biaukula, L. Tikoduadua, J. R. Carapetis, J. Nelson, A. W. Jenney, L. Waqatakirewa, S. Colquhoun, Y. B. Cheung, M. L. Tang, and E. K. Mulholland. 2010. Safety and immunogenicity of the 23-valent pneumococcal polysaccharide vaccine at 12 months of age, following one, two, or three doses of the 7-valent pneumococcal conjugate vaccine in infancy. Vaccine 28:3086-3094.
40. Singleton, R. J., T. W. Hennessy, L. R. Bulkow, L. L. Hammitt, T. Zulz, D. A. Hurlburt, J. C. Butler, K. Rudolph, and A. Parkinson. 2007. Invasive pneumococcal disease caused by nonvaccine serotypes among Alaska native children with high levels of 7-valent pneumococcal conjugate vaccine coverage. JAMA 297:1784-1792.
41. van Gils, E. J., R. H. Veenhoven, E. Hak, G. D. Rodenburg, D. Bogaert, E. P. Ijzerman, J. P. Bruin, L. van Alphen, and E. A. Sanders. 2009. Effect of reduced-dose schedules with 7-valent pneumococcal conjugate vaccine on nasopharyngeal pneumococcal carriage in children: a randomized controlled trial. JAMA 302:159-167.
42. Veenhoven, R., D. Bogaert, C. Uiterwaal, C. Brouwer, H. Kiezebrink, J. Bruin, E. Ijzerman, P. Hermans, R. de Groot, B. Zegers, W. Kuis, G. Rijkers, A. Schilder, and E. Sanders. 2003. Effect of conjugate pneumococcal vaccine followed by polysaccharide pneumococcal vaccine on recurrent acute otitis media: a randomised study. Lancet 361:2189-2195.
43. Veenhoven, R. H., D. Bogaert, A. G. Schilder, G. T. Rijkers, C. S. Uiterwaal, H. H. Kiezebrink, M. J. van Kempen, I. J. Dhooge, J. Bruin, E. P. Ijzerman, R. de Groot, W. Kuis, P. W. Hermans, and E. A. Sanders. 2004. Nasopharyngeal pneumococcal carriage after combined pneumococcal conjugate and polysaccharide vaccination in children with a history of recurrent acute otitis media. Clin. Infect. Dis. 39:911-919.
44. Whitney, C. G., M. M. Farley, J. Hadler, L. H. Harrison, N. M. Bennett, R. Lynfield, A. Reingold, P. R. Cieslak, T. Pilishvili, D. Jackson, R. R. Facklam, J. H. Jorgensen, and A. Schuchat. 2003. Decline in invasive pneumococcal disease after the introduction of protein-polysaccharide conjugate vaccine. N. Engl. J. Med. 348:1737-1746.
45. Wright, P. F., S. H. Sell, W. K. Vaughn, C. Andrews, K. B. McConnell, and G. Schiffman. 1981. Clinical studies of pneumococcal vaccines in infants. II. Efficacy and effect on nasopharyngeal carriage. Rev. Infect. Dis. 3(Suppl.):S108-S112.
46. Zhou, F., F. Kong, Z. Tong, and G. L. Gilbert. 2007. Identification of lesscommon Streptococcus pneumoniae serotypes by a multiplex PCR-based reverse line blot hybridization assay. J. Clin. Microbiol. 45:3411-3415.