Effect of pneumococcal conjugate vaccination on serotype-specific carriage and invasive disease in England: A cross-sectional study

PLoS Medicine

Volumn 8, Issue 4, 2011, Pages 14-

  Flasche, Stefan ^a,b   van Hoek, Albert Jan ^a   Sheasby, Elizabeth ^a   Waight, Pauline ^a   Andrews, Nick ^a   Sheppard, Carmen ^a   George, Robert ^a   Miller, Elizabeth ^a  

^a PUBLIC HEALTH ENGLAND   (United Kingdom)

^b UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PNEUMOCOCCUS VACCINE; VACCINE;

ADOLESCENT; ADULT; ARTICLE; BACTERIUM CARRIER; BACTERIUM ISOLATE; CHILD; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DRUG EFFICACY; HUMAN; INFECTION RISK; INVASIVE PNEUMOCOCCAL DISEASE; NONHUMAN; OUTCOME ASSESSMENT; PNEUMOCOCCAL INFECTION; PRESCHOOL CHILD; RISK REDUCTION; SCHOOL CHILD; SEROTYPE; STREPTOCOCCUS PNEUMONIAE; SYSTEMIC DISEASE; THROAT CULTURE; UNITED KINGDOM; VACCINATION; CLASSIFICATION; COMMUNICABLE DISEASE; FEMALE; HETEROZYGOTE; IMMUNOLOGY; MALE; METHODOLOGY; MICROBIOLOGY; NASOPHARYNX; PREVALENCE; PREVENTIVE HEALTH SERVICE; RISK; SEROTYPING;

ADOLESCENT; ADULT; CARRIER STATE; CHILD; CHILD, PRESCHOOL; COMMUNICABLE DISEASES; CROSS-SECTIONAL STUDIES; ENGLAND; FEMALE; HUMANS; IMMUNIZATION PROGRAMS; MALE; NASOPHARYNX; ODDS RATIO; PNEUMOCOCCAL INFECTIONS; PNEUMOCOCCAL VACCINES; PREVALENCE; SEROTYPING; STREPTOCOCCUS PNEUMONIAE; VACCINATION; VACCINES, CONJUGATE; YOUNG ADULT;

EID: 79955509218     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.1001017     Document Type: Article

References (33)

1. Brueggemann AB, Griffiths DT, Meats E, Peto T, Crook DW, et al. (2003) Clonal relationships between invasive and carriage Streptococcus pneumoniae and serotype- and clone-specific differences in invasive disease potential. J Infect Dis 187: 1424-1432.
2. Weinberger DM, Trzcinski K, Lu Y-J, Bogaert D, Brandes A, et al. (2009) Pneumococcal capsular polysaccharide structure predicts serotype prevalence. PLoS Pathog 5: e1000476 doi:10.1371/journal.ppat.1000476.
3. Calix JJ, Nahm MH, (2010) A new pneumococcal serotype, 11E, has a variably inactivated wcjE gene. J Infect Dis 202: 29-38.
4. Black S, Shinefield H, Fireman B, Lewis E, Ray P, et al. (2000) Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in children. Northern California Kaiser Permanente Vaccine Study Center Group. Pediatr Infect Dis J 19: 187-195.
5. Dagan R, Melamed R, Muallem M, Piglansky L, Greenberg D, et al. (1996) Reduction of nasopharyngeal carriage of pneumococci during the second year of life by a heptavalent conjugate pneumococcal vaccine. J Infect Dis 174: 1271-1278.
6. Dagan R, Givon-Lavi N, Zamir O, Sikuler-Cohen M, Guy L, et al. (2002) Reduction of nasopharyngeal carriage of Streptococcus pneumoniae after administration of a 9-valent pneumococcal conjugate vaccine to toddlers attending day care centers. J Infect Dis 185: 927-936.
7. Beutels P, Thiry N, Damme PV, (2007) Convincing or confusing? Economic evaluations of childhood pneumococcal conjugate vaccination-a review (2002-2006). Vaccine 25: 1355-1367.
8. Melegaro A, Choi YH, George R, Edmunds WJ, Miller E, et al. (2010) Dynamic models of pneumococcal carriage and the impact of the Heptavalent Pneumococcal Conjugate Vaccine on invasive pneumococcal disease. BMC Infect Dis 10: 90.
9. Pilishvili T, Lexau C, Farley MM, Hadler J, Harrison LH, et al. (2010) Sustained reductions in invasive pneumococcal disease in the era of conjugate vaccine. J Infect Dis 201: 32-41.
10. Wals PD, Robin E, Fortin E, Thibeault R, Ouakki M, et al. (2008) Pneumonia after implementation of the pneumococcal conjugate vaccine program in the province of Quebec, Canada. Pediatr Infect Dis J 27: 963-968.
11. Rodenburg GD, Greeff SC de, Jansen AGCS, Melker HE de, Schouls LM, et al. (2010) Effects of pneumococcal conjugate vaccine 2 years after its introduction, the Netherlands. Emerg Infect Dis 16: 816-823.
12. WHO (2010) Changing epidemiology of pneumococcal serotypes after introduction of conjugate vaccine: July 2010 report. Weekly Epidemiological Record 85: 434-436.
13. Huang SS, Hinrichsen VL, Stevenson AE, Rifas-Shiman SL, Kleinman K, et al. (2009) Continued impact of pneumococcal conjugate vaccine on carriage in young children. Pediatrics 124: e1-11.
14. Vestrheim DF, Høiby EA, Aaberge IS, Caugant DA, (2010) Impact of a pneumococcal conjugate vaccination program on carriage among children in Norway. Clin Vaccine Immunol 17: 325-334.
15. Pelton SI, Huot H, Finkelstein JA, Bishop CJ, Hsu KK, et al. (2007) Emergence of 19A as virulent and multidrug resistant Pneumococcus in Massachusetts following universal immunization of infants with pneumococcal conjugate vaccine. Pediatr Infect Dis J 26: 468-472.
16. Yildirim I, Hanage WP, Lipsitch M, Shea KM, Stevenson A, et al. (2010) Serotype specific invasive capacity and persistent reduction in invasive pneumococcal disease. Vaccine 29: 283-288.
17. Hussain M, Melegaro A, Pebody RG, George R, Edmunds WJ, et al. (2005) A longitudinal household study of Streptococcus pneumoniae nasopharyngeal carriage in a UK setting. Epidemiol Infect 133: 891-898.
18. Lund E, Hendrichsen J, (1978) Laboratory diagnosis, serology and epidemiology of Streptococcus pneumoniae. Methods in microbiology London Academic Press pp. 241-262.
19. Trotter CL, Waight P, Andrews NJ, Slack M, Efstratiou A, et al. (2009) Epidemiology of invasive pneumococcal disease in the pre-conjugate vaccine era: England and Wales, 1996-2006. J Infect 60: 200-208.
20. Sleeman KL, Griffiths D, Shackley F, Diggle L, Gupta S, et al. (2006) Capsular serotype-specific attack rates and duration of carriage of Streptococcus pneumoniae in a population of children. J Infect Dis 194: 682-688.
21. Simpson EH, (1949) Measurement of diversity. Nature 163: 688.
22. Hanage WP, Finkelstein JA, Huang SS, Pelton SI, Stevenson AE, et al. (2010) Evidence that pneumococcal serotype replacement in Massachusetts following conjugate vaccination is now complete. Epidemics 2: 80-84.
23. Gils EJM van, Veenhoven RH, Hak E, Rodenburg GD, Bogaert D, et al. (2009) Effect of reduced-dose schedules with 7-valent pneumococcal conjugate vaccine on nasopharyngeal pneumococcal carriage in children: a randomized controlled trial. JAMA 302: 159-67.
24. Miller E, Andrews NJ, Waight PA, Slack MPE, George RC, (2011) Herd immunity and serotype replacement four years after pneumococcal conjugate vaccination in England and Wales: An observational cohort study. Lancet Infect Dis In press.
25. HPA (2010) Pneumococcal disease. Available: http://www.hpa.org.uk/Topics/InfectiousDiseases/InfectionsAZ/Pneumococcal/. Accessed 29 July 2010.
26. Salisbury D, (2010) Introduction of Prevenar 13 ® into the Childhood Immunisation Programme. Available: http://www.dh.gov.uk/prod_consum_dh/groups/dh_digitalassets/documents/digitalasset/dh_112192.pdf. Accessed 4 June 2010.
27. Turner P, Hinds J, Turner C, Jankhot A, Gould K, et al. (2011) Improved detection of nasopharyngeal co-colonization by multiple pneumococcal serotypes using latex agglutination or molecular serotyping by microarray. J Clin Microbiol doi:10.1128/JCM.00157-11.
28. Abdullahi O, Nyiro J, Lewa P, Slack M, Scott JAG, (2008) The descriptive epidemiology of Streptococcus pneumoniae and Haemophilus influenzae nasopharyngeal carriage in children and adults in Kilifi district, Kenya. Pediatr Infect Dis J 27: 59-64.
29. Hill PC, Townend J, Antonio M, Akisanya B, Ebruke C, et al. (2010) Transmission of Streptococcus pneumoniae in rural Gambian villages: a longitudinal study. Clin Infect Dis 50: 1468-1476.
30. Brugger SD, Frey P, Aebi S, Hinds J, Muehlemann K, (2010) Multiple colonization with S. pneumoniae before and after introduction of the seven-valent conjugated pneumococcal polysaccharide vaccine. PLoS One 5: e11638 doi:10.1371/journal.pone.0011638.
31. Harboe ZB, Benfield TL, Valentiner-Branth P, Hjuler T, Lambertsen L, et al. (2010) Temporal trends in invasive pneumococcal disease and pneumococcal serotypes over 7 decades. Clin Infect Dis 50: 329-337.
32. Gray BM, Converse GM, Dillon HC, (1980) Epidemiologic studies of Streptococcus pneumoniae in infants: acquisition, carriage, and infection during the first 24 months of life. J Infect Dis 142: 923-933.
33. Weinberger DM, Harboe ZB, Sanders EAM, Ndiritu M, Klugman KP, et al. (2010) Association of serotype with risk of death due to pneumococcal pneumonia: a meta-analysis. Clin Infect Dis 51: 692-699.