Ultrasonographic measures of synovitis in an early phase clinical trial: A double-blind, randomised, placebo and comparator controlled phase IIa clinical trial of GW274150 (a selective inducible nitric oxide synthase inhibitor) in rheumatoid arthritis

Clinical and Experimental Rheumatology

Volumn 30, Issue 2, 2012, Pages 254-261

  Seymour, Matthew ^a   Pétavy, Frank ^b   Chiesa, Flaminia ^b   Perry, Hayley ^b   Lukey, Pauline T ^b   Binks, Michael ^b   Donatien, Philippe D ^a   Freidin, Andrew J ^a   Eckersley, Robert J ^c   McClinton, Catherine ^a   Heath, Kathleen ^a   Prodanovic, Slavica ^d   Radunovic, Goran ^d   Pilipovic, Nada ^d   Damjanov, Nemanja ^d   Taylor, Peter C ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d INSTITUTE OF RHEUMATOLOGY   (Serbia)

Author keywords

Corticosteroids; Metacarpophalangeal joint; Power Doppler; Rheumatoid arthritis; Ultrasonographic

Indexed keywords

C REACTIVE PROTEIN; PLACEBO; PREDNISONE; S [2 (1 IMINOETHYLAMINO)ETHYL]HOMOCYSTEINE; VASCULOTROPIN;

ABDOMINAL PAIN; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG EFFICACY; DRUG FATALITY; DRUG RESPONSE; DRUG SAFETY; DRUG WITHDRAWAL; ECHOGRAPHY; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; HEADACHE; HUMAN; LOW DRUG DOSE; MALE; METACARPOPHALANGEAL JOINT; MULTICENTER STUDY; OUTCOME ASSESSMENT; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RHEUMATOID ARTHRITIS; STEADY STATE; SYNOVITIS; TREND STUDY; URTICARIA; VASCULARIZATION; VOMITING;

ADULT; AGED; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; DISABILITY EVALUATION; DOUBLE-BLIND METHOD; ENGLAND; ENZYME INHIBITORS; FEMALE; HUMANS; MALE; METACARPOPHALANGEAL JOINT; MIDDLE AGED; NITRIC OXIDE SYNTHASE TYPE II; PLACEBOS; PREDICTIVE VALUE OF TESTS; PREDNISOLONE; SERBIA; SULFIDES; SYNOVITIS; TIME FACTORS; TREATMENT OUTCOME; ULTRASONOGRAPHY, DOPPLER;

EID: 84863771050     PISSN: 0392856X     EISSN: 1593098X     Source Type: Journal    
DOI: None     Document Type: Article

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