Physiopathology of esophageal inflammation, ulcerogenesis and repair by studying the profile of glycoconjugate

Frontiers of Gastrointestinal Research

Volumn 30, Issue , 2012, Pages 148-160

  Zayachkivska, Oksana ^a  

^a DANYLO HALYTSKY LVIV NATIONAL MEDICAL UNIVERSITY   (Ukraine)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLYCOCONJUGATE; N ACETYLNEURAMINIC ACID; NITROGEN; SIALOGLYCOPROTEIN;

CELL ACTIVATION; CELL DAMAGE; CELL MIGRATION; CELL POPULATION; CELL PROLIFERATION; CONFERENCE PAPER; CYTOTOXICITY; DISEASE COURSE; ENDOTHELIUM CELL; EPITHELIUM CELL; ESOPHAGUS INJURY; ESOPHAGUS MUCOSA; GASTROESOPHAGEAL REFLUX; GLYCOBIOLOGY; HELIX POMATIA; HUMAN; MOLECULAR BIOLOGY; NON EROSIVE REFLUX DISEASE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RECURRENT DISEASE; REFLUX ESOPHAGITIS; SAMBUCUS NIGRA; SURVIVAL; TISSUE INJURY; TRITICUM AESTIVUM; ULCER; ULCER HEALING; ULCEROGENESIS;

EID: 84863754512     PISSN: 03020665     EISSN: 16623754     Source Type: Book Series    
DOI: 10.1159/000338434     Document Type: Conference Paper

References (30)

1. Modlin IM, Hunt RH, Malfertheiner P, Moayyedi P, Quigley EM, Tytgat GNJ, Tack J, Heading RC, Holtman G, Moss SF: Diagnosis and management of non-erosive reflux disease -The Vevey NERD Consensus Group. Digestion 2009;80:74-88.
2. Orlando RC, Paterson WG, Harnett K, et al: Esophageal disease: updated information on inflammation. Ann NY Acad Sci 2011;1232:369-375.
3. Mechref Y, Hussein A, Bekesova S, Pungpapong V, Zhang M, Dobrolecki LE, Hickey RJ, Hammoud ZT, Novotny MV: Quantitative serum glycomics of esophageal adenocarcinoma and other esophageal disease onsets. J Proteome Res 2008;8:2656-2666.
4. Modlin IM, Moss SF, Kidd M, Lye KD: Gastroesophageal reflux disease: then and now. J Clin Gastroenterol 2004;38:390-402.
5. Malfertheiner MV, Fill S, Kidd M, Modlin IM: The elucidation of peptic esophagitis: from Hamperl to heartburn. Z Gastroenterol 2007;45:1164-1168.
6. Varki A, Cummings RD, Esko JD, et al (eds): Essentials of Glycobiology, ed 2. New York, Cold Spring Harbor, 2009.
7. Bilyy R, Stoika R: Search for novel cell surface markers of apoptotic cells. Autoimmunity 2007; 40:249-253.
8. Kamiya Y, Satoh T, Kato K: Molecular and structural basis for N-glycan-dependent determination of glycoprotein fates in cells. Biochim Biophys Acta 2012, DOI:10.1016/j.bbagen.2011.12.017
9. Telford JE, Doherty MA, Tharmalingam T, Rudd PM: Discovering new clinical markers in the field of glycomics. Biochem Soc Trans 2011;39:327-330.
10. Cooper D, Iqbal AJ, Gittens BR, Cervone C, Perretti M: The effect of galectins on leukocyte trafficking in inflammation: sweet or sour? Ann NY Acad Sci 2012, DOI: 10.1111/j.1749-6632.2011.06291.
11. Hopwood D, Logan KR, Coghill G, Bouchier IA: Histochemical studies of mucosubstances and lipids in normal human oesophageal epithelium. Histochem J 1977;9:153-161.
12. Zayachkivska OS, Gzhegotsky MR, Terletska OI, Lutsyk DA, Yaschenko AM, Dzhura OR: Influence of Viburnum opulus proanthocyanidins on stressinduced gastrointestinal mucosal damage. J Physiol Pharmacol 2006;57:155-167.
13. Orlando RC: The integrity of the esophageal mucosa. Balance between offensive and defensive mechanisms. Best Pract Res Clin Gastroenterol 2010;24:873-882.
14. Solcia E, Villani L, Luinetti O, Trespi E, Strada E, Tinelli C, Fiocca R: Altered intercellular glycoconjugates and dilated intercellular spaces of esophageal epithelium in reflux disease. Virchows Arch 2000;436:207-216.
15. Nagahama K, Yamoto M, Nishio H, Takeuchi K: Essential role of pepsin in pathogenesis of acid reflux esophagitis in rats. Dig Dis Sci 2006;51:303-309.
16. Zaiachkivska OS, Hzhehotskyi MP, Slivovskyi Z, Bzhozovskyi T, Konturek SIa, Dzhura OP, Iashchenko AM: Model studies of the involvement of nitric oxide, prostanoids, and glucoconjugates of epithelial barrier of the esophagus in the process of esophagus protection (in Ukrainian). Lik Sprava 2006;7:35-41.
17. Zayachkivska OS, Dzhura OR, Yaschenko AM: Investigation vasoactive effect of melatonin on expression lectin receptors during experimental esophagitis in vivo. Bukovinian Med J 2006;10:47-49.
18. Konturek SJ, Zayachkivska O, Havryluk XO, Brzozowski T, Sliwowski Z, Pawlik M, Konturek PC, Czesnikiewicz-Guzik M, Gzhegotsky MR, Pawlik WW: Protective influence of melatonin against acute esophageal lesions involves prostaglandins, nitric oxide and sensory nerves. J Physiol Pharmacol 2007;58:361-177.
19. Pawlik M, Pajdo R, Kwiecien S, Ptak-Belowska A, Sliwowski Z, Mazurkiewicz-Janik M, Konturek SJ, Pawlik WW, Brzozowski T: Nitric oxide (NO)-releasing aspirin exhibits a potent esophagoprotection in experimental model of acute reflux esophagitis. Role of nitric oxide and proinflammatory cytokines. J Physiol Pharmacol 2011;62:75-86.
20. Filaretova L: Glucocorticoids are gastroprotective under physiological conditions. Ther Adv Chronic Dis 2011;2:333-342.
21. Savytska M, Zayachkivska O, Gzregotsky M, Yaschenko A: Features of expression special carbohydrate components in glycoprotein receptors on epithelial barrier of esophagus during healing stressinduced lesions (experimental study). Pract Med 2009;2:69-80.
22. Savytska M, Zayachkivska O, Gzhegotsky MR, Yaschenko AM: Physiopathological role of crosstalk of sialic acid N-acytelneuroaminic acid (NEU5AC) and inflammation in regulating esophageal barrier (EB) healing during experimental esophagitis (ES). 19th EUDW, Barcelona, 2010 (abstract). Gut 2010; 59(suppl III):A142.
23. Savytska M, Filipskyy A, Zayachkivska O, Gzhegotsky MR, Yaschenko AM: Increased vascular endothelial growth factor (VEGF) activity and modification in glycoconjugates expression profile precede esophageal epithelial barrier (EEB) dysfunction in the repair of experimental non-erosive esophagitis: the impact of angiogenesis in the mechanism of age-depended healing. 18th EUDW, London, 2009 (abstract). Gut 2009;58(suppl II): A123.
24. Savytska M, Zayachkivska O, Gzhegotsky M, Yaschenko A, Lutsyk A: Significant enrichment of esophageal defense by probiotics: novel implications for an esophageal healing effect from viewpoint of glycocomic biomarkers. Global Alliance for Life Sciences: Bridges in Life Sciences US-CEE Regional networking Meeting IV, Debrecen, 2009, pp 58-59.
25. Hrycevych N, Zvir M, Zayachkivska O, Gzhegotsky M: Effect of proinflammatory cytokine-mediated mechanism of quality of gastro-intestinal restitutio ad integrum. Ann Univ Mariae Curie-Sklodowska 2010;28:211-214.
26. Yoo J, Lotz MM, Matthews JB: Cytokines in restitution. Gastrointestinal mucosal repair and experimental therapeutics. Front Gastrointest Res. Basel, Karger, 2002, vol 25, pp 14-28.
27. Vanderschaeghe D, Festjens N, Delanghe J, Callewaert N: Glycome profiling using modern glycomics technology: technical aspects and applications. Biol Chem 2010;391:149-161.
28. Yamamoto K, Qi WM, Yokoo Y, Miyata H, Udayanga KG, Kawano J, Yokoyama T, Hoshi N, Kitagawa H: Lectin histochemical detection of special sugars on the mucosal surfaces of the rat alimentary tract. J Vet Med Sci 2010;72:1119-1127.
29. Zayachkivska O, Gzregotsky M, Ferentc M, Yaschenko A, Urbanovych A: Effects of nitrosative stress and reactive oxygen-scavenging systems in esophageal physiopathy under streptozotocininduced experimental hyperglycemia. J Physiol Pharmacol 2008;59:77-87.
30. Zayachkivska O, Gzhegotsky MR, Yaschenko AM, Pinyajko RO: Modification of glycoconjugates signaling pathway during esophageal barrier injury induced by experimental hypergastrinemia. Ann Univ Mariae Curie-Sklodowska 2009;3:41-45.