Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts

Journal of Cellular Biochemistry

Volumn 84, Issue 1, 2002, Pages 12-26

  Safadi, Fayez F ^a   Xu, Jie ^a   Smock, Steven L ^b   Rico, Mario C ^a   Owen, Thomas A ^b   Popoff, Steven N ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Osteoactivin; Osteoblast differentiation; Osteopetrosis

Indexed keywords

ALKALINE PHOSPHATASE; AMINO ACID; COMPLEMENTARY DNA; MESSENGER RNA; OSTEOACTIVIN; OSTEOCALCIN; RNA; UNCLASSIFIED DRUG;

ALBERS SCHOENBERG DISEASE; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MATRIX; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; GENE EXPRESSION; GLYCOSYLATION; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; OSSIFICATION; OSTEOBLAST; OSTEOLYSIS; PRIORITY JOURNAL; RAT; SEQUENCE ANALYSIS;

EID: 0035185649     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.1259     Document Type: Article

References (32)

1. Gene array analysis of osteoblast differentiation
2. Best5: A novel interferon-inducible gene expressed during bone formation
3. Regulation of mineral homeostasis in osteopetrotic (op) rats
4. Control of osteoclastogenesis and bone resorption by members of the TNF family of receptors and ligands
5. A melanocyte-specific gene, Pmel 17, maps near the silver coat color locus on mouse chromosome 10 and is in a syntenic region on human chromosome 12
6. The CCN family of angiogenic regulators: The integrin connection
7. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction
8. Distribution and cloning of eukaryotic mRNAs by means of differential display: Refinements and optimization
9. The structure and development of bone
10. Osteoclast biology in the osteopetrotic (op) rat
11. Mechanically regulated expression of a neural glutamate transporter in bone: A role for excitatory amino acids as osteotropic agents?
12. Connective tissue growth factor: What's in a name?
13. Progressive development of the rat osteoblast phenotype in vitro: Reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix
14. Identification of osteoblast/osteocyte 45 (OF45), a bone-specific cDNA encoding an RGD-containing protein that is highly expressed in osteoblasts and osteocytes
15. The heterogeneity of the osteopetroses reflects the diversity of cellular influences during skeletal development
16. Animal models of osteopetrosis: The impact of recent molecular developments on novel strategies for therapeutic intervention
17. Interdependence of skeletal sclerosis and elevated circulating levels of 1.25-dihydroxyvitamin D in osteopetrotic (op and tl) rats
18. 3
19. Detection of a proliferation specific gene during development of the osteoblast phenotype by mRNA differential display
20. Skeletal resistance to 1,25-dihydroxyvitamin D3 in osteopetrotic rats
21. Experimental studies of osteopetrosis in laboratory animals
22. Coordinate expression of novel genes during osteoblast differentiation
23. Gene expression during skeletal development in three osteopetrotic rat mutations
24. Mechanisms Regulating osteoblast proliferation and differentiation
25. Bone resorption by osteoclasts
26. Presence of messenger ribonucleic acid encoding osteocalcin, a marker of bone turnover, in bone marrow megakaryocytes and peripheral blood platelets
27. The stem cell of the osteoblast
28. nmb, a novel gene, is expressed in low-metastatic human melanoma cell lines and xenografts
29. Cloning the full-length cDNA for rat connective tissue growth factor: Implications for skeletal development
30. A defect in the inflammation-primed macrophage-activation cascade in osteopetrotic rats
31. A novel osteoblast-derived c-type lectin that inhibits osteoclast formation