Novel insights into the innate immune response to non-tuberculous Mycobacteria

Immunology and Cell Biology

Volumn 90, Issue 6, 2012, Pages 568-570

  Heinz, Leonhard X ^a   Schroder, Kate ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

INFLAMMASOME; INTERLEUKIN 1BETA; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR;

ATYPICAL MYCOBACTERIOSIS; ENZYME ACTIVATION; IMMUNE RESPONSE; INNATE IMMUNITY; MYCOBACTERIUM ABSCESSUS; NOTE; PROTEIN AGGREGATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CARRIER PROTEINS; HUMANS; INFLAMMASOMES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LECTINS, C-TYPE; MACROPHAGES; NONTUBERCULOUS MYCOBACTERIA; PROTEIN-TYROSINE KINASES;

CORYNEBACTERINEAE;

EID: 84863727054     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2011.86     Document Type: Note

References (11)

1. Schroder K, Tschopp J. The inflammasomes. Cell 2010; 140: 821-832.
2. Lee H-M, Yuk J-M, Kim K-H, Jang J, Kang G, Park JB et al. Mycobacterium abscessus activates the NLRP3 inflammasome via Dectin-1-Syk and p62/SQSTM1. Immunol Cell Biol 2012; 90: 601-610.
3. Gross O, Poeck H, Bscheider M, Dostert C, Hannesschlager N, Endres S et al. Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence. Nature 2009; 459: 433-436.
4. Medjahed H, Gaillard JL, Reyrat JM. Mycobacterium abscessus: a new player in the mycobacterial field. Trends Microbiol 2010; 18: 117-123.
5. Marakalala MJ, Graham LM, Brown GD. The role of Syk/ CARD9-coupled C-type lectin receptors in immunity to Mycobacterium tuberculosis infections. Clin Dev Immunol 2010; 2010: 567571.
6. Mayer-Barber KD, Barber DL, Shenderov K, White SD, Wilson MS, Cheever A et al. Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivo. J Immunol 2010; 184: 3326-3330.
7. McElvania Tekippe E, Allen IC, Hulseberg PD, Sullivan JT, McCann JR, Sandor M et al. Granuloma formation and host defense in chronic Mycobacterium tuberculosis infection requires PYCARD/ ASC but not NLRP3 or caspase-1. PLoS One 2010; 5: e12320.
8. Shin DM, Yang CS, Yuk JM, Lee JY, Kim KH, Shin SJ et al. Mycobacterium abscessus activates the macrophage innate immune response via a physical and functional interaction between TLR2 and dectin-1. Cell Microbiol 2008; 10: 1608-1621.
9. Moscat J, Diaz-Meco MT. p62 at the crossroads of autophagy, apoptosis, and cancer. Cell 2009; 137: 1001-1004.
10. Deretic V. Autophagy in immunity and cell-autonomous defense against intracellular microbes. Immunol Rev 2011; 240: 92-104.
11. Dupont N, Lacas-Gervais S, Bertout J, Paz I, Freche B, Van Nhieu GT et al. Shigella phagocytic vacuolar membrane remnants participate in the cellular response to pathogen invasion and are regulated by autophagy. Cell Host Microbe 2009; 6: 137-149.