The methodology of negative pressure wound therapy: Separating fact from fiction

Journal of Plastic, Reconstructive and Aesthetic Surgery

Volumn 65, Issue 8, 2012, Pages 989-1001

  Glass, Graeme E ^a   Nanchahal, Jagdeep ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Interface material; Negative pressure wound therapy; Tissue perfusion; VAC; Wound filler

Indexed keywords

GROWTH FACTOR; POLYURETHAN FOAM;

BACTERIAL COLONIZATION; BLOOD FLOW; CELL PROLIFERATION; HUMAN; MECHANOTRANSDUCTION; MEDICAL DEVICE; METHODOLOGY; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; TISSUE PERFUSION; VACUUM ASSISTED CLOSURE; WOUND CONTRACTION; WOUND HEALING;

ANIMALS; HUMANS; NEGATIVE-PRESSURE WOUND THERAPY; TREATMENT OUTCOME; WOUND HEALING; WOUNDS AND INJURIES;

EID: 84863723080     PISSN: 17486815     EISSN: 18780539     Source Type: Journal    
DOI: 10.1016/j.bjps.2011.12.012     Document Type: Review

References (82)

1. M.E. Chariker, T.L. Gerstle, and C.S. Morrison An algorithmic approach to the use of gauze-based negative-pressure wound therapy as a bridge to closure in pediatric extremity trauma Plast Reconstr Surg 123 2009 1510 1520
2. M.E. Chariker, K.F. Jeter, and T.E. Tintle Effective management of incisional and cutaneous fistulae with closed suction wound drainage Contemp Surg 34 1989 59 63
3. W. Fleischmann, E. Lang, and L. Kinzl Vacuum assisted wound closure after dermatofasciotomy of the lower extremity Unfallchirurg 99 1996 283 287
4. W. Fleischmann, E. Lang, and M. Russ Treatment of infection by vacuum sealing Unfallchirurg 100 1997 301 304
5. W. Fleischmann, M. Russ, and C. Marquardt Closure of defect wounds by combined vacuum sealing with instrumental skin expansion Unfallchirurg 99 1996 970 974
6. W. Fleischmann, W. Strecker, and M. Bombelli Vacuum sealing as treatment of soft tissue damage in open fractures Unfallchirurg 96 1993 488 492
7. L.C. Argenta, and M.J. Morykwas Vacuum-assisted closure: a new method for wound control and treatment: clinical experience Ann Plast Surg 38 1997 563 576 [discussion 577]
8. M.J. Morykwas, L.C. Argenta, and E.I. Shelton-Brown Vacuum-assisted closure: a new method for wound control and treatment: animal studies and basic foundation Ann Plast Surg 38 1997 553 562
9. Agency for Healthcare research and Quality 2009 http://www.ahrq.gov/ clinic/ta/negpresswtd/
10. FDA safety communication: UPDATE on serious complications associated with negative pressure wound therapy systems 2011 http://www.fda.gov/MedicalDevices/ Safety/AlertsandNotices/ucm244211.htm
11. F. Peinemann, N. McGauran, and S. Sauerland Disagreement in primary study selection between systematic reviews on negative pressure wound therapy BMC Med Res Methodol 8 2008 41
12. L.C. Argenta, M.J. Morykwas, and M.W. Marks Vacuum-assisted closure: state of clinic art Plast Reconstr Surg 117 2006 127S 142S
13. D.P. Orgill, and L.R. Bayer Update on negative-pressure wound therapy Plast Reconstr Surg 127 Suppl 1 2011 105S 115S
14. D.P. Orgill, E.K. Manders, and B.E. Sumpio The mechanisms of action of vacuum assisted closure: more to learn Surgery 146 2009 40 51
15. S. Gregor, M. Maegele, and S. Sauerland Negative pressure wound therapy: a vacuum of evidence? Arch Surg 143 2008 189 196
16. C.M. Moues, F. Heule, and S.E. Hovius A review of topical negative pressure therapy in wound healing: sufficient evidence? Am J Surg 201 2011 544 556
17. D.T. Ubbink, S.J. Westerbos, and D. Evans Topical negative pressure for treating chronic wounds Cochrane Database Syst Rev 2008 CD001898
18. D.T. Ubbink, S.J. Westerbos, and E.A. Nelson A systematic review of topical negative pressure therapy for acute and chronic wounds Br J Surg 95 2008 685 692
19. X. Xie, M. McGregor, and N. Dendukuri The clinical effectiveness of negative pressure wound therapy: a systematic review J Wound Care 19 2010 490 495
20. F. Peinemann, N. McGauran, and S. Sauerland Negative pressure wound therapy: potential publication bias caused by lack of access to unpublished study results data BMC Med Res Methodol 8 2008 4
21. T. Wild, S. Stremitzer, and A. Budzanowski Definition of efficiency in vacuum therapy-a randomised controlled trial comparing with V.A.C. Therapy Int Wound J 5 2008 641 647
22. A. Wackenfors, J. Sjogren, and R. Gustafsson Effects of vacuum-assisted closure therapy on inguinal wound edge microvascular blood flow Wound Repair Regen 12 2004 600 606
23. A. Wackenfors, R. Gustafsson, and J. Sjogren Blood flow responses in the peristernal thoracic wall during vacuum-assisted closure therapy Ann Thorac Surg 79 2005 1724 1730 [discussion 1730-1721]
24. P. Dastouri, D.L. Helm, and S.S. Scherer Waveform modulation of negative-pressure wound therapy in the murine model Plast Reconstr Surg 127 2011 1460 1466
25. S.L.A. Jeffery Advanced wound therapies in the manangement of severe military lower limb trauma: a new perspective eplasty vol. 9 2009 Open Science Co.
26. O. Borgquist, R. Ingemansson, and M. Malmsjo Individualizing the use of negative pressure wound therapy for optimal wound healing: a focused review of the literature Ostomy Wound Manage 57 2011 44 54
27. O. Borgquist, L. Gustafsson, and R. Ingemansson Micro- and macromechanical effects on the wound bed of negative pressure wound therapy using gauze and foam Ann Plast Surg 64 2011 789 793
28. C.A. Moyer, L. Brentano, and D.L. Gravens Treatment of large Human burns with 0.5 Percent silver nitrate solution Arch Surg 90 1965 812 867
29. M. Spear Silver: an age-old treatment modality in modern times Plast Surg Nurs 30 2010 90 93
30. R. Gerry, S. Kwei, and L. Bayer Silver-impregnated vacuum-assisted closure in the treatment of recalcitrant venous stasis ulcers Ann Plast Surg 59 2007 58 62
31. F. Vin, L. Teot, and S. Meaume The healing properties of Promogran in venous leg ulcers J Wound Care 11 2002 335 341
32. Monstrey, S., Hoeksema, H., Verbelen, J. http://clinicaltrials.gov/ct2/ show/NCT01107821. 2011.
33. S.M. Jones, P.E. Banwell, and P.G. Shakespeare Interface dressings influence the delivery of topical negative-pressure therapy Plast Reconstr Surg 116 2005 1023 1028
34. R. Petzina, M. Ugander, and L. Gustafsson Hemodynamic effects of vacuum-assisted closure therapy in cardiac surgery: assessment using magnetic resonance imaging J Thorac Cardiovasc Surg 133 2007 1154 1162
35. M. Malmsjo, S. Lindstedt, and R. Ingemansson Influence on pressure transduction when using different drainage techniques and wound fillers (foam and gauze) for negative pressure wound therapy Int Wound J 7 2010 406 412
36. T. Takei, I. Mills, and K. Arai Molecular basis for tissue expansion: clinical implications for the surgeon Plast Reconstr Surg 102 1998 247 258
37. J.G. McCarthy, J. Schreiber, and N. Karp Lengthening the human mandible by gradual distraction Plast Reconstr Surg 89 1992 1 8 [discussion 9-10]
38. J. Folkman, and A. Moscona Role of cell shape in growth control Nature 273 1978 345 349
39. K. Nishimura, P. Blume, and S. Ohgi Effect of different frequencies of tensile strain on human dermal fibroblast proliferation and survival Wound Repair Regen 15 2007 646 656
40. V. Saxena, C.W. Hwang, and S. Huang Vacuum-assisted closure: microdeformations of wounds and cell proliferation Plast Reconstr Surg 114 2004 1086 1096 [discussion 1097-1088]
41. G. Pietramaggiori, P. Liu, and S.S. Scherer Tensile forces stimulate vascular remodeling and epidermal cell proliferation in living skin Ann Surg 246 2007 896 902
42. S.S. Scherer, G. Pietramaggiori, and J.C. Mathews The mechanism of action of the vacuum-assisted closure device Plast Reconstr Surg 122 2008 786 797
43. S. Jacobs, D.A. Simhaee, and A. Marsano Efficacy and mechanisms of vacuum-assisted closure (VAC) therapy in promoting wound healing: a rodent model J Plast Reconstr Aesthet Surg 62 2009 1331 1338
44. R. Wilkes, Y. Zhao, and K. Kieswetter Effects of dressing type on 3D tissue microdeformations during negative pressure wound therapy: a computational study J Biomech Eng 131 2009 031012
45. J.K. Stechmiller, D.V. Kilpadi, and B. Childress Effect of Vacuum-Assisted Closure Therapy on the expression of cytokines and proteases in wound fluid of adults with pressure ulcers Wound Repair Regen 14 2006 371 374
46. K. Norbury, and K. Kieswetter Vacuum-assisted closure therapy attenuates the inflammatory response in a porcine acute wound healing model Wounds 19 2007 97 106
47. D.V. Kilpadi, C.E. Bower, and C.C. Reade Effect of Vacuum Assisted Closure Therapy on early systemic cytokine levels in a swine model Wound Repair Regen 14 2006 210 215
48. S.A. Eming, T. Krieg, and J.M. Davidson Inflammation in wound repair: molecular and cellular mechanisms J Invest Dermatol 127 2007 514 525
49. A.J. Singer, and R.A. Clark Cutaneous wound healing N Engl J Med 341 1999 738 746
50. M.J. Morykwas, B.J. Faler, and D.J. Pearce Effects of varying levels of subatmospheric pressure on the rate of granulation tissue formation in experimental wounds in swine Ann Plast Surg 47 2001 547 551
51. C. Ahearn Intermittent NPWT and lower negative pressures-exploring the disparity between science and current practice: a review Ostomy Wound Manage 55 2009 22 28
52. N. Kairinos, M. Solomons, and D.A. Hudson The paradox of negative pressure wound therapy-in vitro studies J Plast Reconstr Aesthet Surg 63 2010 174 179
53. N. Kairinos, M. Solomons, and D.A. Hudson Negative-pressure wound therapy I: the paradox of negative-pressure wound therapy Plast Reconstr Surg 123 2009 589 598 [discussion 599-600]
54. N. Kairinos, A.M. Voogd, and P.H. Botha Negative-pressure wound therapy II: negative-pressure wound therapy and increased perfusion. Just an illusion? Plast Reconstr Surg 123 2009 601 612
55. J. Pinocy, J.M. Albes, and C. Wicke Treatment of periprosthetic soft tissue infection of the groin following vascular surgical procedures by means of a polyvinyl alcohol-vacuum sponge system Wound Repair Regen 11 2003 104 109
56. S.H. Wu, P.J. Zecha, and R. Feitz Vacuum therapy as an intermediate phase wound closure: a clinical experience Eur J Plast Surg 23 2000 174 177
57. C.M. Moues, M.C. Vos, and G.J. van den Bemd Bacterial load in relation to vacuum-assisted closure wound therapy: a prospective randomized trial Wound Repair Regen 12 2004 11 17
58. T. Weed, C. Ratliff, and D.B. Drake Quantifying bacterial bioburden during negative pressure wound therapy: does the wound VAC enhance bacterial clearance? Ann Plast Surg 52 2004 276 279 [discussion 279-280]
59. A. Braakenburg, M.C. Obdeijn, and R. Feitz The clinical efficacy and cost effectiveness of the vacuum-assisted closure technique in the management of acute and chronic wounds: a randomized controlled trial Plast Reconstr Surg 118 2006 390 397 [discussion 398-400]
60. O. Assadian, A. Assadian, and M. Stadler Bacterial growth kinetic without the influence of the immune system using vacuum-assisted closure dressing with and without negative pressure in an in vitro wound model Int Wound J 7 2010 283 289
61. P. Banwell, S. Withey, and I. Holten The use of negative pressure to promote healing Br J Plast Surg 51 1998 79
62. M.S. Miller, and C.A. Lowery Negative pressure wound therapy: "a rose by any other name" Ostomy Wound Manage 51 2005 44 46 48-49
63. O. Borgquist, L. Gustafsson, and R. Ingemansson Tissue ingrowth into foam but not into gauze during negative pressure wound therapy. Wounds 21 2009 Health Management Publications Inc.
64. O. Borgquist, R. Ingemansson, and M. Malmsjo Wound edge microvascular blood flow during negative-pressure wound therapy: examining the effects of pressures from -10 to -175 mmHg Plast Reconstr Surg 125 2010 502 509
65. O. Borgquist, R. Ingemansson, and M. Malmsjo The influence of low and high pressure levels during negative-pressure wound therapy on wound contraction and fluid evacuation Plast Reconstr Surg 127 2011 551 559
66. M.S. Rendell, M.L. Johnson, and D. Smith Skin blood flow response in the rat model of wound healing: expression of vasoactive factors J Surg Res 107 2002 18 26
67. M.S. Rendell, B.K. Milliken, and M.F. Finnegan The skin blood flow response in wound healing Microvasc Res 53 1997 222 234
68. P.G. Rodriguez, F.N. Felix, and D.T. Woodley The role of oxygen in wound healing: a review of the literature Dermatol Surg 34 2008 1159 1169
69. N. Kairinos, D. Hudson, and M. Solomons Depth of penetration of negative pressure wound therapy into underlying tissues Wound Repair Regen 17 2009 456
70. M. Malmsjo, R. Ingemansson, and R. Martin Wound edge microvascular blood flow: effects of negative pressure wound therapy using gauze or polyurethane foam Ann Plast Surg 63 2009 676 681
71. M.J. Morykwas, J. Simpson, and K. Punger Vacuum-assisted closure: state of basic research and physiologic foundation Plast Reconstr Surg 117 2006 121S 126S
72. M.S. Timmers, S. Le Cessie, and P. Banwell The effects of varying degrees of pressure delivered by negative-pressure wound therapy on skin perfusion Ann Plast Surg 55 2005 665 671
73. S. Lindstedt, M. Malmsjo, and J. Sjogren Impact of different topical negative pressure levels on myocardial microvascular blood flow Cardiovasc Revasc Med 9 2008 29 35
74. S. Lindstedt, P. Paulsson, and A. Mokhtari A compare between myocardial topical negative pressure levels of -25 mmHg and -50 mmHg in a porcine model BMC Cardiovasc Disord 8 2008 14
75. T. Isago, M. Nozaki, and Y. Kikuchi Effects of different negative pressures on reduction of wounds in negative pressure dressings J Dermatol 30 2003 596 601
76. M. Malmsjo, R. Ingemansson, and R. Martin Negative-pressure wound therapy using gauze or open-cell polyurethane foam: similar early effects on pressure transduction and tissue contraction in an experimental porcine wound model Wound Repair Regen 17 2009 200 205
77. S. Lindstedt, M. Malmsjo, and B. Gesslein Evaluation of continuous and intermittent myocardial topical negative pressure J Cardiovasc Med (Hagerstown) 9 2008 813 819
78. S.S. Scherer, G. Pietramaggiori, and J.C. Mathews Short periodic applications of the vacuum-assisted closure device cause an extended tissue response in the diabetic mouse model Plast Reconstr Surg 124 2009 1458 1465
79. A.K. McNulty, M. Schmidt, and T. Feeley Effects of negative pressure wound therapy on fibroblast viability, chemotactic signaling, and proliferation in a provisional wound (fibrin) matrix Wound Repair Regen 15 2007 838 846
80. A.K. McNulty, I. Spanger, and J. Courage The Consistent delivery of negative pressure to wounds using Reticulated, open cell foam and Regulated negative Feedback Wounds 22 2010 114 120
81. T. Mullner, L. Mrkonjic, and O. Kwasny The use of negative pressure to promote the healing of tissue defects: a clinical trial using the vacuum sealing technique Br J Plast Surg 50 1997 194 199
82. S. Ichioka, H. Watanabe, and N. Sekiya A technique to visualize wound bed microcirculation and the acute effect of negative pressure Wound Repair Regen 16 2008 460 465