In silico nanodosimetry: New insights into nontargeted biological responses to radiation

Computational and Mathematical Methods in Medicine

Volumn 2012, Issue , 2012, Pages

  Kuncic, Zdenka ^a   Byrne, Hilary L ^a   McNamara, Aimee L ^a   Guatelli, Susanna ^b   Domanova, Westa ^a,c   Incerti, Sébastien ^d  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF WOLLONGONG   (Australia)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; FREE RADICALS; RADIATION DAMAGE;

BIOLOGICAL RESPONSE; CHEMICAL COMPOSITIONS; ELECTROMAGNETIC INTERACTIONS; MICROBEAM IRRADIATION; RADIATION-INDUCED; REALISTIC SIMULATION; SIGNALLING PATHWAYS; SIMULATION STUDIES;

DNA;

CELL NUCLEUS DNA; DNA; FREE RADICAL; ION; PROTON; WATER;

ARTICLE; CELL DAMAGE; CELL DEATH; CELL MEMBRANE; COMPUTER MODEL; DOSIMETRY; ELECTROMAGNETIC RADIATION; GENE TARGETING; HUMAN; IONIZATION; LYSOSOME; MICRODOSIMETRY; MITOCHONDRION; NANOANALYSIS; NANODOSIMETRY; RADIATION PROCESSING; SIMULATION; CELL NUCLEUS; CHEMISTRY; COMPUTER SIMULATION; CYTOPLASM; DNA DAMAGE; ELECTRON; KERATINOCYTE; METABOLISM; METHODOLOGY; MUTAGENESIS; NANOTECHNOLOGY; PHOTON; RADIATION EXPOSURE; RADIOBIOLOGY; SIGNAL TRANSDUCTION; STATISTICAL MODEL; THEORETICAL MODEL;

CELL DEATH; CELL NUCLEUS; COMPUTER SIMULATION; CYTOPLASM; DNA; DNA DAMAGE; ELECTRONS; FREE RADICALS; HUMANS; IONS; KERATINOCYTES; LYSOSOMES; MITOCHONDRIA; MODELS, STATISTICAL; MODELS, THEORETICAL; MUTAGENESIS; NANOTECHNOLOGY; PHOTONS; PROTONS; RADIOBIOLOGY; SIGNAL TRANSDUCTION; WATER;

EID: 84863708518     PISSN: 1748670X     EISSN: 17486718     Source Type: Journal    
DOI: 10.1155/2012/147252     Document Type: Article

References (55)

1. Bohr N., On the decrease of velocity of swiftly moving electrified particles in passing through matter Philosophical Magazine 1915 25 10
2. Bethe H., Zur theorie des durchgangs schneller korpuskularstrahlen durch materie Annalen der Physik 1930 5 325
3. Bethe H., Heitler W., On the stopping of fast particles and on the creation of positive electrons Proceedings of the Royal Society of London A 1934 146 83
4. Fano U., Atomic theory of electromagnetic interactions in dense materials Physical Review 1956 103 5 1202 1218
5. Goodhead D. T., The initial physical damage produced by ionizing radiations International Journal of Radiation Biology 1989 56 5 623 634 (Pubitemid 20002008)
6. Harper J. W., Elledge S. J., The DNA damage response: ten years after Molecular Cell 2007 28 5 739 745 (Pubitemid 350217064)
7. Lea D. E., The Action of Radiation on Living Cells 1946 London, UK Cambridge University Press
8. Elkind M. M., Sutton H., X-ray damage and recovery in mammalian cells in culture Nature 1959 184 4695 1293 1295
9. Munro T. R., Gilbert C. W., The relation between tumour lethal doses and the radiosensitivity of tumour cells. The British journal of radiology 1961 34 246 251
10. Kellerer A. M., Rossi H. H., The theory of dual radiation action Current Topics in Radiation Research 1972 8 85
11. Chadwick K. H., Leenhouts H. P., The Molecular Theory of Radiation Biology 1981 Berlin Springer
12. Prise K. M., Schettino G., Folkard M., Held K. D., New insights on cell death from radiation exposure Lancet Oncology 2005 6 7 520 528 (Pubitemid 40903633)
13. Tubiana M., Can we reduce the incidence of second primary malignancies occurring after radiotherapy? A critical review Radiotherapy and Oncology 2009 91 1 4 15
14. Takam R., Bezak E., Yeoh E. E., Risk of second primary cancer following prostate cancer radiotherapy: DVH analysis using the competitive risk model Physics in Medicine and Biology 2009 54 3 611 625
15. Newhauser W. D., Durante M., Assessing the risk of second malignancies after modern radiotherapy Nature Reviews Cancer 2011 11 6 438 448
16. Rodemann H. P., Blaese M. A., Responses of normal cells to ionizing radiation Seminars in Radiation Oncology 2007 17 2 81 88 (Pubitemid 46467380)
17. Xu X. G., Bednarz B., Paganetti H., A review of dosimetry studies on external-beam radiation treatment with respect to second cancer induction Physics in Medicine and Biology 2008 53 13 R193 R241
18. Denham J. W., Walker Q. J., Lamb D. S., Hamilton C. S., O'Brien P. C., Spry N. A., Hindley A., Poulsen M., O'Brien M., Tripcony L., Mucosal regeneration during radiotherapy Radiotherapy and Oncology 1996 41 2 109 118 (Pubitemid 26423621)
19. Wu L.-J., Randers-Pehrson G., Xu A., Waldren C. A., Geard C. R., Yu Z., Hei T. K., Targeted cytoplasmic irradiation with alpha particles induces mutations in mammalian cells Proceedings of the National Academy of Sciences of the United States of America 1999 96 9 4959 4964 (Pubitemid 29214518)
20. Shao C., Folkard M., Michael B. D., Prise K. M., Targeted cytoplasmic irradiation induces bystander responses Proceedings of the National Academy of Sciences of the United States of America 2004 101 37 13495 13500 (Pubitemid 39238431)
21. Prise K. M., O'Sullivan J. M., Radiation-induced bystander signalling in cancer therapy Nature Reviews Cancer 2009 9 5 351 360
22. Averbeck D., Non-targeted effects as a paradigm breaking evidence Mutation Research 2010 687 1-2 7 12
23. Wright E. G., Manifestations and mechanisms of non-targeted effects of ionizing radiation Mutation Research 2010 687 1-2 28 33
24. Schettino G., Al Rashid S. T., Prise K. M., Radiation microbeams as spatial and temporal probes of subcellular and tissue response Mutation Research 2010 704 13 68 77
25. Nikjoo H., Lindborg L., RBE of low energy electrons and photons Physics in Medicine and Biology 2010 55 10 R65 R109
26. Goodhead D. T., An assessment of the role of microdosimetry in radiobiology Radiation Research 1982 91 1 45 76 (Pubitemid 12092072)
27. Grosswendt B., Recent advances of nanodosimetry Radiation Protection Dosimetry 2004 110 14 789 799 (Pubitemid 39276833)
28. Schulte R. W., Nanodosimetry: principle and current status 1345 Proceedings of the AIP Conference 2011 249
29. Nettelbeck H., Rabus H., Nanodosimetry: the missing link between radiobiology and radiation physics? Radiation Measurements 2011 48 893
30. Nikjoo H., Emfietzoglou D., Watanabe R., Uehara S., Can Monte Carlo track structure codes reveal reaction mechanism in DNA damage and improve radiation therapy? Radiation Physics and Chemistry 2008 77 10-12 1270 1279
31. Brenner D. J., Ward J. F., Constraints on energy deposition and target size of multiply damaged sites associated with DNA double-strand breaks International Journal of Radiation Biology 1992 61 6 737 748
32. Goodhead D. T., Initial events in the cellular effects of ionizing radiations: clustered damage in DNA International Journal of Radiation Biology 1994 65 1 7 17 (Pubitemid 24063524)
33. Nikjoo H., O'Neill P., Goodhead D. T., Terrissol M., Computational modelling of low-energy electron-induced DNA damage by early physical and chemical events International Journal of Radiation Biology 1997 71 5 467 483 (Pubitemid 27229743)
34. Bernal M. A., Dealmeida C. E., Sampaio C., Incerti S., Champion C., Nieminen P., The invariance of the total direct DNA strand break yield Medical Physics 2011 38 7 4147 4153
35. McNamara A. L., Guatelli S., Prokopovich D. A., Reinhard M. I., Rosenfeld A. B., A comparison of x-ray and proton beam low energy secondary electron track structures using the low energy models of Geant4 International Journal of Radiation Biology 2012 88 1-2 164 170
36. Landau L. D., Pitaevskii L. P., Lifshitz E. P., Electrodynamics of Continuous Media 1984 2nd Pergamon, Greece Oxford
37. Ritchie R. H., Energy losses by swift charged particles in the bulk and at the surface of condensed matter Nuclear Instruments and Methods In Physics Research 1982 198 1 81 91
38. Landau L. D., Lifshitz E. P., Quantum MechanicsNon-Relativistic Theory 1977 3rd Pergamon, Greece Oxford
39. Fano U., Penetration of protons, alpha particles and mesons Annual Review of Nuclear and Particle Science 1963 13 1
40. Berestetskii V. B., Pitaevskii L. P., Lifshitz E. P., Quantum Electrodynamics 1982 2nd Oxford, UK Butterworth-Heinmann
41. Dingfelder M., Ritchie R. H., Turner J. E., Friedland W., Paretzke H. G., Hamm R. N., Comparisons of calculations with PARTRAC and NOREC: transport of electrons in liquid water Radiation Research 2008 169 5 584 594 (Pubitemid 351671524)
42. Emfietzoglou D., Nikjoo H., Accurate electron inelastic cross sections and stopping powers for liquid water over the 0.1-10 keV range based on an improved dielectric description of the Bethe surface Radiation Research 2007 167 1 110 120 (Pubitemid 46106803)
43. Champion C., Electron impact ionization of liquid and gaseous water: a single-center partial-wave approach Physics in Medicine and Biology 2010 55 1 11 32
44. Agostinelli S., Geant4a simulation toolkit Nuclear Instruments and Methods in Physics Research A 2003 506 250
45. Allison J., Geant4 developments and applications IEEE Transactions on Nuclear Science 2006 53 270
46. Incerti S., Ivanchenko A., Karamitros M., Mantero A., Moretto P., Tran H. N., Mascialino B., Champion C., Ivanchenko V. N., Bernal M. A., Francis Z., Villagrasa C., Baldacchino G., Gye P., Capra R., Nieminen P., Zacharatou C., Comparison of GEANT4 very low energy cross section models with experimental data in water Medical Physics 2010 37 9 4692 4708
47. Wilson C. D., Dukes C. A., Baragiola R. A., Search for the plasmon in condensed water Physical Review B 2001 63 12 1 4
48. Geissler P. L., Dellago C., Chandler D., Hutter J., Parrinello M., Autoionization in liquid water Science 2001 291 5511 2121 2124 (Pubitemid 32224437)
49. Jahnke T., Ultrafast energy transfer between water molecules Nature Physics 2010 6 139
50. Mucke M., Braune M., Barth S., Frstel M., Lischke T., Ulrich V., Arion T., Becker U., Bradshaw A., Hergenhahn U., A hitherto unrecognized source of low-energy electrons in water Nature Physics 2010 6 2 143 146
51. Champion C., Incerti S., Aouchiche H., Oubaziz D., A free-parameter theoretical model for describing the electron elastic scattering in water in the Geant4 toolkit Radiation Physics and Chemistry 2009 78 9 745 750
52. Chauvie S., Francis Z., Guatelli S., Incerti S., Mascialino B., Moretto P., Nieminen P., Pia M. G., Geant4 physics processes for microdosimetry simulation: design foundation and implementation of the first set of models IEEE Transactions on Nuclear Science 2007 54 6 2619 2628 (Pubitemid 350274127)
53. Chauvie S., Incerti S., Moretto P., Pia M. G., Seznec H., Microdosimetry in high-resolution cellular phantoms using the very low energy electromagnetic extension of the Geant4 toolkit Proceedings of the IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS-MIC '07) November 2007 2086 2088
54. Incerti S., Seznec H., Simon M., Barberet P., Habchi C., Moretto P., Monte Carlo dosimetry for targeted irradiation of individual cells using a microbeam facility Radiation Protection Dosimetry 2009 133 1 2 11
55. Alard J.-P., Bodez V., Tchirkov A., Nénot M.-L., Arnold J., Crespin S., Rapp M., Verrelle P., Dionet C., Simulations of neutron interactions at the single-cell level Radiation Research 2002 158 5 650 656 (Pubitemid 35266198)