Geant4 physics processes for microdosimetry simulation: Design foundation and implementation of the first set of models

IEEE Transactions on Nuclear Science

Volumn 54, Issue 6, 2007, Pages 2619-2628

  Chauvie, S ^a   Francis, Z ^b   Guatelli, S ^c   Incerti, S ^d   Mascialino, B ^c   Moretto, P ^d   Nieminen, P ^e   Pia, M G ^c  

^a S CROCE E CARLE HOSPITAL   (Italy)

^b UNIVERSITÉ CLERMONT AUVERGNE   (France)

^c INFN SEZIONE DI GENOVA   (Italy)

^d CENTRE D ETUDES NUCLÉAIRES DE BORDEAUX GRADIGNAN   (France)

^e EUROPEAN SPACE AGENCY   (Netherlands)

Author keywords

Geant4; Geant4 DNA; Microdosimetry; Monte Carlo; Simulation

Indexed keywords

BIOLOGICAL SYSTEMS; COMPUTER SIMULATION; ELECTRONICS PACKAGING; MATHEMATICAL MODELS; MONTE CARLO METHODS;

GEANT4; GEANT4-DNA; LIQUID WATER; LOW ENERGY SCALE; MICRODOSIMETRY;

DOSIMETRY;

EID: 37249073929     PISSN: 00189499     EISSN: None     Source Type: Journal    
DOI: 10.1109/TNS.2007.910425     Document Type: Conference Paper

References (92)

1. D. Blanc and M. Terrissol, "Microdosimetry: A tool for radiation research," Radiat. Prot. Dosim., vol. 13, no. 1-4, pp. 387-393, 1985.
2. S. Agostinelli et al., "Geant4 - A simulation toolkit," Nucl. Instrum. Meth. A, vol. 506, no. 3, pp. 250-303, 2003.
3. J. Allison et al., "Geant4 developments and applications," IEEE Trans. Nucl. Sci., vol. 53, no. 1, pp. 270-278, Feb. 2006.
4. S. Chauvie, G. Depaola, V. Ivanchenko, F. Longo, P. Nieminen, and M. G. Pia, "Geant4 low energy electromagnetic physics," in Proc. Comput. High Energy Nuclear Phys., 2001, pp. 337-340.
5. S. Chauvie et al., "Geant4 low energy electromagnetic physics," in Conf. Rec. IEEE Nucl. Sci. Symp., 2004, pp. N33-165.
6. J. Lakos, Large-Scale C++ Software Design. Boston, MA: Addison-Wesley, 1996.
7. A. Santovincenzo et al., "Human missions to Mars," ESA, Noordwijk, The Netherlands, ESA Rep. CDF 20(A), 2004.
8. G. Hornee et al., "HUMEX, a study on the survivability and adaptation of humans to long-duration interplanetary and planetary environments," Adv. Space. Res., vol. 31, no. 11, pp. 2389-2401, 2003.
9. S. J. Hoffman and D. L. Kaplan, "Human exploration of Mars: The reference mission of the NASA Mars exploration study team," NASA Johnson Space Center, Houston, TX, SP-6107, 1997.
10. W. R. Nelson, H. Hirayama, and D. W. O. Rogers, "The EGS4 code system," Stanford Linear Accelerator Center, Stanford, CA, Tech. Rep. SLAC-265, 1985,.
11. I. Kawrakow and D. W. O. Rogers, "The EGSnrc code system: Monte Carlo simulation of electron and photon transport," NRCC, Ottawa, Canada, Tech. Rep. PIRS-701, 2006.
12. H. Hirayama, Y. Namito, A. F. Bielajew, S. J. Wilderman, and W. R. Nelson, "The EGS5 code system," Stanford Linear Accelerator Center, Stanford, CA, Tech. Rep. SLAC-R-730, 2006,.
13. A. Fenari, P. R. Sala, A. Fassò, and J. Ranft, "Fluka: A multi-particle transport code," CERN, Geneva, Switzerland, Tech. Rep. CERN-2005-010, INFN/TC-05/11, SLAC-R-773, 2005.
14. A. Fassò et al., "The physics models of FLUKA: Status and recent developments," presented at the Comput. High Energy Nucl. Phys. Conf. (CHEP), La Jolla, CA, 2003, MOMT005.
15. "MCNP -A general Monte Carlo N-particle transport code, version 5," X-5 Monte Carlo Team, Los Alamos National Laboratory, Los Alamos, NM, Tech. Rep. LA-UR-03-1987, 2003.
16. R. A. Forster et al., "MCNP version 5," Nucl. Instrum. Meth. B, vol. 213, pp. 82-86, 2004.
17. J. S. Hendricks et al., "MCNPX 2.3.0 user's guide (unrestricted distribution version)," Los Alamos National Laboratory, Los Alamos, NM, Tech. Rep. LA-UR-02-2607, 2002.
18. J. S. Hendricks et al., "MCNPX, version 26c," Los Alamos National Laboratory, Los Alamos, NM, Tech. Rep. LA-UR-06-7991, 2006.
19. M. J. Berger, "Monte Carlo calculation of the penetration and diffusion of fast charged particles," in Methods in Computational Physics. NewYork: Academic, 1963, pp. 135-215.
20. M. Zaider, D. J. Brenner, and W. E. Wilson, "The application of track calculations to radiobiology: I. Monte Carlo simulation of proton tracks," Radiat. Res., vol. 95, pp. 231-247, 1983.
21. H. G. Paretzke, "Radiation track structure theory," in Kinetics of NonHomogeneous Processes. New York: Wiley, 1987, pp. 89-170.
22. W. E. Wilson and H. G. Paretzke, "Calculation of distribution of energy imparted and ionisations by fast protons in nanometer sites," Radiat. Res., vol. 81, pp. 521-537, 1981.
23. A. Ito, "Electron track simulation for microdosimetry," in Monte Carlo Transport of Electrons and Photons. New York: Plenum, 1988, pp. 361-382.
24. S. Uehara, H. Nikjoo, and D. T. Goodhead, "Cross-sections for water vapor for the Monte Carlo electron track structure code from 10 eV to the MeV region," Phys. Med. Bio., vol. 37, pp. 1841-1858, 1992.
25. A. V. Lappa, E. A. Bigildeev, D. S. Burmistrov, and O. N. Vasilyev, "Trion code for radiation action calculations and its application in microdosimetry and radiobiology," Radiat. Environ. Biophys., vol. 32, pp. 1-19, 1993.
26. C. Champion, "Multiple ionization of water by heavy ions: A Monte Carlo approach," Nucl. Instrum. Meth. B, vol. 205, pp. 671-676, 2003.
27. W. E. Wilson and H. Nikjoo, "A Monte Carlo code for positive ion track simulation," Radiat. Environ. Biophys., vol. 38, pp. 97-104. 1999.
28. S. Uehara, L. H. Toburen, and H. Nikjoo, "Development of a Monte Carlo track structure code for low-energy protons in water," Int. J. Radiat. Biol., vol. 77, pp. 138-154, 2001.
29. D. Emfietzoglou, G. Papamichael, and M. Moscovitch, "An event-byevent computer simulation of interactions of energetic charged particles and all their secondary electrons in water," J. Phys. D: Appl. Phys., vol. 33, pp. 932-944, 2000.
30. D. Emfietzoglou, G. Papamichael, K. Kostarelos, and M. Moscovitch, "A Monte Carlo track structure code for electrons (10 eV-10 keV) and protons (0.3-10 Mev) in water: Partitioning of energy and collision events," Phys. Med. Biol., vol. 45, pp. 3171-3194, 2000.
31. D. Emfietzoglou, G. Papamichael, and M. Moscovitch, "Charged particle interactions in water: Cross sections and simulations," Radiat. Phys. Chem., vol. 61, pp. 597-598, 2001.
32. M. Terrissol and A. Beaudre, "Simulation of space and time evolution of radiolytic species induced by electrons in water," Radiat. Prot. Dosim., vol. 31, pp. 171-175, 1990.
33. S. M. Pimblott, J. A. LaVerne, A. Mozumder, and N. J. B. Green, "Structure of electron tracks in water. 1. Distribution of energy deposition events," J. Phys. Chem., vol. 94, pp. 488-495, 1990.
34. R. H. Ritchie et al., "Radiation interactions and energy transport in the condensed phase," in Physical and Chemical Mechanisms in Molecular-Radiation Biology. New York: Plenum, 1991, pp. 99-136.
35. M. Zaider, M. G. Vracko, A. Y. C. Fung, and J. L. Fry, "Electron transport in condensed water," Radiat. Prot. Dosim., vol. 52, pp. 139-146, 1994.
36. M. A. Hill and F. A. Smith, "Calculation of initial and primary yields in the radiolysis of water," Int. J. Appl. Radiat. Isot., vol. 43, pp. 265-280, 1994.
37. V. Cobut, Y. Frongillo, J. P. Patau, T. Goulet, M. J. Fraser, and J. P. Jay-Gerin, "Monte Carlo simulation of fast electron and proton tracks in liquid water I. Physical and physicochemical aspects," Radiat, Phys. Chem., vol. 51, pp. 229-243, 1998.
38. V. A. Semenenko et al., "NOREC, a Monte Carlo code for simulating electron tracks in liquid water," Radiat. Environ. Biophys., vol. 42, pp. 213-217, 2003.
39. H. Nikjoo, S. Uehara, W. E. Wilson, M. Hoshi, and D. T. Goodhead, "Track structure in radiation biology: Theory and applications," Int. J. Radiat. Biol., vol. 73, no. 4, pp. 355-364, 1998.
40. S. Uehara, H. Nikjoo, and D. T. Goodhead, "Comparison and assessment of electron cross sections for Monte Carlo track structure codes," Radiat. Res., vol. 152, pp. 202-213, 1999.
41. J. E. Turner, H. G. Paretzke, R. N. Hamm, H. A. Wright, and R. H. Ritchie, "Comparative study of electron energy deposition and yields in water in the liquid and vapour phases," Radiat. Res., vol. 92, pp. 47-60, 1982.
42. H. Nikjoo et al., "Comparison of energy deposition in small cylindrical volumes by electrons generated by Monte Carlo track structure codes for gaseous and liquid water," Radiat. Prot. Dosim., vol. 52, no. 1-4, pp. 164-169, 1994.
43. H. Nikjoo, "Radiation track and DNA damage," Iran. J. Radiat. Res., vol. 1, pp. 3-16, 2003.
44. W. Gilbert, "Towards a paradigm shift in biology," Nature, vol. 349, no. 6305, p. 99, 1991.
45. IEEE Recommended Practice for Software Acquisition, IEEE Standard 1062, 1998.
46. P. Kettunen and M. Laanti, "How to steer an embedded software project: Tactics for selecting the software process model," Inf. Softw. Technol., vol. 47, pp. 587-608, 2005.
47. W. W. Royce, "Managing the development of large software systems," in Proc. IEEE WESCON, 1970, pp. 328-338.
48. C. Larman and V. R. Basili, "Iterative and incremental developments: A brief history," Computer, vol. 36, no. 6, pp. 47-46, Jun. 2003.
49. I. Jacobson, J. Booch, and J. Rumbaugh, The Unified Software Development Process, 1st ed. New York: Addison-Wesley, 1999.
50. S. Guatelli et al., "Experience with software process in physics projects," in Proc. Conf. Rec. IEEE Nucl. Sci. Symp., pp. 2100-2103.
51. P. Krachten, The Rational Unified Process: An Introduction, 3rd ed. New York: Addison-Wesley, 2003.
52. Rational Software Corporation, Cupertino, CA, Assessing the rational unified process against ISO/IEC 15504-5," 2000.
53. J. M. Simon, "ISO/IEC DTR 15504 Part 5: An assessment model and indicator guidance," ISO/IEC Joint Technical Committee 1, Geneva. Switzerland, 1999.
54. G. Cosmo, "Geant4 software process," presented at the CHEP - Comput. High Energy Phys., Beijing, China, 2001.
55. P. Sawyer, I. Sommerville, and S. Viller, "Capturing the benefits of requirements engineering," IEEE Softw., vol. 16, no. 2, pp. 78-85, 1999.
56. A. Alexandrescu, Modern C++ Design. New York: Addison-Wesley, 2001.
57. E. Gamma, R. Helm, R. Johnson, and J. Vlissides, Design Patterns. New York: Addison-Wesley, 1995.
58. J. P. Wellisch, "Hadronic shower models in Geant4 -The frameworks," Comp. Phys. Commun., vol. 140, no. 1, pp. 65-75, Oct. 2001.
59. G. Booch, J. Rumbaugh. and I. Jacobson, The Unified Modeling Language User Guide. New York: Addison-Wesley, 1999.
60. J. M. Heller, Jr, R. N. Hamm, R. D. Birkhoff, and L. R. Painter, "Collective oscillation in liquid water," J. Chem. Phys., vol. 60, no. 9, pp. 3483-3486, 1974.
61. H. Hayashi, N. Watanabe, and Y. Udagawa, "Optical spectra of liquid water in vacuum UV region by means of inelastic X-ray spectroscopy," J. Chem. Phys., vol. 108, no. 3, pp. 823-825, 1998.
62. H. G. Paretzke, J. E. Turner, R. N. Hamm, H. A. Wright, and R. H. Ritchie, "Calculated yields and fluctuations for electron degradation in liquid water and water vapor," J. Chem. Phys., vol. 84, pp. 3182-3188, 1986.
63. D. Emfietzoglou et al., "A Monte-Carlo study of sub-keV electron transport in water: The influence of the condensed phase," Nucl. Instrum. Meth. B, vol. 228, pp. 341-348, 2005.
64. D. Emfietzoglou and H. Nikjoo, "The effect of model approximations on single-collision distributions of low-energy electrons in liquid water," Radiat. Res., vol. 163, no. 1, pp. 98-111 2005.
65. 2 O : Influence of the state of aggregation," Nucl. Instr. Meth. B, vol. 93, pp. 132-136, 1994.
66. D. J. Brenner and M. Zaider, "A computationally convenient parameterization of experimental angular distributions of low energy electrons elastically scattered off water vapour," Phys. Med. Biol., vol. 29, no. 4, pp. 443-447, 1983.
67. H. Bethe, "Molière theory of multiple scattering," Phys. Rev., vol. 89, pp. 1256-1266, 1953.
68. G. Molière, "Theorie der Streuung schneller geladener teilchen. I. Einzelstteuung am abgeschirmten coulomb-feld," Z. Naturf., vol. A2, pp. 133-145, 1947.
69. G. Molière, "Theorie der Streuung schneller geladener Teilchen. Ii. Mehrfach- und Vielfachstreuung," Z. Naturf., vol. A3, pp. 78-97, 1948.
70. B. Grosswendt and E. Waibel, "Transport of low energy electrons in nitrogen and air," Nucl. Instrum. Meth., vol. 155, pp. 145-156, 1978.
71. B. Senger, S. Fall, and R. V. Rechenmann, "Semi-empirical expressions describing the elastic scattering of slow electrons by molecules," Rad. Prot. Dosim., vol. 31, pp. 37-42, 1990.
72. D. Emfietzoglou and M. Moscovitch, "Inelastic collision characteristics of electrons in liquid water," Nucl. Instrum. Meth. B, vol. 193, pp. 71-78, 2002.
73. D. Emfietzoglou, K. Karava, G. Papamichael, and M. Moscovitch, "Monte Carlo simulation of the energy loss of low-energy electrons in liquid water," Phys. Med. Biol., vol. 48, pp. 2355-2371, 2003.
74. M. Dingfelder, M. lnokuti, and H. G. Paretzke, "Inelastic-collision cross sections of liquid water for interactions of energetic protons," Radiat. Phys. Chem., vol. 59, pp. 255-275, 2000.
75. D. H. Wright et al., "Recent developments and validations in Geant4 Hadronic physics," in Proc. XII Int. Conf. Calorimetry High Energy Phys., 2006, pp. 479-486.
76. J. H. Miller and A. E. S. Green, "Proton energy degradation in water vapor," Radiat. Res., vol. 54, pp. 343-363, 1973.
77. M. E. Rudd, T. V. Goffe, R. D. DuBois, and L. H. Toburen, "Cross sections for ionisation of water vapor by 7-4000 keV protons," Phys. Rev. A, vol. 31, pp. 492-494, 1985.
78. M. E. Rudd, Y. K. Kim, D. H. Madison, and J. W. Gallagher, "Electron production in proton collisions: Total cross sections," Rev. Mod. Phys., vol. 57, no. 4, pp. 965-994, 1985.
79. M. Dingfelder, "Private communication," Dept. Phys., East Carolina Univ., Greenville, SC, 2005.
80. M. E. Rudd, "User-friendly model for the energy distribution of electrons from proton or electron collisions," Nucl. Tracks Rod. Meas., vol. 16, no. 2-3, pp. 213-218, 1989.
81. M. E. Rudd, "Energy and angular distributions of secondary electrons from 5-100 keV proton collisions with hydrogen and nitrogen molecules," Phys. Rev., vol. A20, pp. 787-796, 1979.
82. 2O: Absolute differential and integral cross sections," Phys. Rev. A, vol. 55, no. 5, pp. 3945-3946, 1997.
83. + with a water-vapour target," J. Phys. B, vol. 3, pp. 1239-1251, 1970.
84. L. H. Toburen, M. Y. Nakai, and R. A. Langley, "Measurement of highenergy charge transfer cross sections for incident protons and atomic hydrogen in various gases," Phys. Rev., vol. 171, no. 1, pp. 114-122, 1968.
85. M. Dingfelder, H. G. Paretzke, and L. H. Toburen, "An effective charge scaling model for ionization of partially dressed helium ions with liquid water," presented at the Monte Carlo, Chattanooga, TN, 2005.
86. IEEE Standard for Software Verification and Validation, IEEE Standard 1012-2004, 2005, Revision of IEEE Standard 1012-1998.
87. JTC1/SC22/WG21 - The C++ Standards Committee, Geneva, Switzerland, "Programming language C++,", ISO/IEC 14882, 2003.
88. 16 gases," Nucl. Fus., vol. 10, pp. 145-149, 1970.
89. D. W. Koopman, "Light-ion charge exchange in atmospheric gases," Phys. Rev., vol. 166, pp. 57-62, 1968.
90. 2O molecules," Lawrence Radiation Laboratory, Livermore, CA, Tech. Rep. UCRL-14214, 1965.
91. 3," J. Chem. Phys., vol. 52, pp. 4154-4160, 1970.
92. M. E. Rudd, T. V. Goffe, R. D. DuBois, and L. H. Toburen, "Cross sections for ionisation of water vapor by 7-4000 keV protons," Phys. Rev. A, vol. 31, pp. 492-494, 1985.