Which is the best anticoagulant for whole blood aggregometry platelet function testing Comparison of six anticoagulants and diverse storage conditions

Platelets

Volumn 23, Issue 5, 2012, Pages 359-367

  Kaiser, Andreas Friedrich Christoph ^a   Neubauer, Horst ^a   Franken, Cora Christina ^a   Krüger, Jan Christoph ^a   Mügge, Andreas ^a   Meves, Saskia Hannah ^a  

^a ST JOSEF HOSPITAL   (Germany)

Author keywords

Anticoagulants; Impedance aggregometry; Platelet aggregation; Storage time

Indexed keywords

ADENOSINE DIPHOSPHATE; ANTICOAGULANT AGENT; ARACHIDONIC ACID; BENZYLSULFONYL DEXTRO ARGILYLPROLYL 4 AMIDINOBENZYLAMIDE; CITRIC ACID; HEPARIN; HEPARIN LITHIUM; HIRUDIN; UNCLASSIFIED DRUG;

ANTICOAGULATION; ARTICLE; BLOOD CLOTTING PARAMETERS; ELECTRODE; FEMALE; HUMAN; IMPEDANCE AGGREGOMETRY; LABORATORY DEVICE; MALE; NORMAL HUMAN; PRIORITY JOURNAL; STORAGE TEMPERATURE; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION;

ANTICOAGULANTS; BLOOD PLATELETS; BLOOD PRESERVATION; CITRIC ACID; ELECTRIC IMPEDANCE; FEMALE; HUMANS; MALE; PLATELET AGGREGATION; PLATELET FUNCTION TESTS;

EID: 84863705081     PISSN: 09537104     EISSN: 13691635     Source Type: Journal    
DOI: 10.3109/09537104.2011.624211     Document Type: Article

References (42)

1. Paniccia R, Antonucci E, Maggini N, Miranda M, Gori AM, Marcucci R, Giusti B, Balzi D, Prisco D, Abbate R. Comparison of methods for monitoring residual platelet reactivity after clopidogrel by point-of-care tests on whole blood in high-risk patients. Thromb Haemost 2010;104:287-292.
2. Sibbing D, Morath T, Braun S, Stegherr J, Mehilli J, Vogt W, Schömig A, Kastrati A, von Beckerath N. Clopidogrel response status assessed with Multiplate point-of-care analysis and the incidence and timing of stent thrombosis over six months following coronary stenting. Thromb Haemost 2010;103: 151-159.
3. Toth O, Calatzis A, Penz S, Losonczy H, Siess W. Multiple electrode aggregometry: A new device to measure platelet aggregation in whole blood. Thromb Haemost 2006;96: 781-788.
4. Ivandic B, Schlick P, Staritz P, Kurz K, Katus H, Giannitsis E. Determination of clopidogrel resistance by whole blood platelet aggregometry and inhibitors of the P2Y12 receptor. Clin Chem 2006;52:383-388.
5. Ivandic B, Giannitsis E, Schlick P, Staritz P, Katus H, Hohlfeld T. Determination of aspirin responsiveness by use of whole blood platelet aggregometry. Clin Chem 2007;53: 614-619.
6. Neubauer H, Kaiser A, Busse B, Mügge A. Identification, evaluation and treatment of prasugrel low-response after coronary stent implantation - a preliminary study. Thromb Res 2010;126:e389-391.
7. Neubauer H, Kaiser AF, Endres HG, Krüger JC, Engelhardt A, Lask S, Pepinghege F, Kusber A, Mügge A. Tailored antiplatelet therapy can overcome clopidogrel and aspirin resistance - The BOchum CLopidogrel and Aspirin Plan (BOCLA-Plan) to improve antiplatelet therapy. BMC Med 2011;9:3.
8. Breddin H. Can platelet aggregometry be standardized? Platelets 2005;16(3-4):151-158.
9. Breddin K, Ziemen M, Bauer O, Herrmann W, Schaudinn L, Schlosser U, Winterhagen A, Krzywanek H. Time and temperature dependent changes of ADP- and collagen-induced and "spontaneous" aggregation. Thromb Res 1980;19(4-5): 621-638.
10. Mani H, Hellis M, Lindhoff-Last E. Platelet function testing in hirudin and BAPA anticoagulated blood. Clin Chem Lab Med 2011;49:501-507.
11. Truss N, Armstrong P, Liverani E, Vojnovic I, Warner T. Heparin but not citrate anticoagulation of blood preserves platelet function for prolonged periods. J Thromb Haemost 2009;7:1897-1905.
12. Belcher P, Muriithi E, Day S, Wheatley D. Platelet aggregatory responses to low-dose collagen are maintained in hirudin-anticoagulated whole blood for 24 h when stored at room temperature. Platelets 2001;12:34-36.
13. Haubelt H, Vogt A, Hellstern P. Preservation of platelet aggregation and dense granule secretion during extended storage of blood samples in the presence of a synthetic dual inhibitor of factor Xa and thrombin. Platelets 2008;19:496-501.
14. Hellstern P, Stürzebecher U, Wuchold B, Haubelt H, Seyfert U, Bauer M, Vogt A, Stürzebecher J. Preservation of in vitro function of platelets stored in the presence of a synthetic dual inhibitor of factor Xa and thrombin. J Thromb Haemost 2007;5:2119-2126.
15. Tauer JT, Lohse J, König S, Knöfler R. Investigations of platelet function in whole blood with BAPA as anticoagulant. Transfus Med Hemother 2010;37:284-288.
16. Kaiser AF, Endres HG, Mügge A, Neubauer H. BAPA, a synthetic dual inhibitor of Factor Xa and Thrombin, extends the storage-time to a maximum of 12 h in ADP- and 24 h in arachidonic acid-induced impedance aggregometry. Scand J Clin Lab Invest 2011;71:253-256.
17. Kalb M, Potura L, Scharbert G, Kozek-Langenecker S. The effect of ex vivo anticoagulants on whole blood platelet aggregation. Platelets 2009;20:7-11.
18. Johnson A, Dovlatova N, Heptinstall S. Multiple electrode aggregometry and P2Y(12) antagonists. Thromb Haemost 2008;99:1127-1129.
19. Seyfert U, Haubelt H, Vogt A, Hellstern P. Variables influencing Multiplate(TM) whole blood impedance platelet aggregometry and turbidimetric platelet aggregation in healthy individuals. Platelets 2007;18:199-206.
20. Ben-Dor I, Kleiman NS, Lev E. Assessment, mechanisms, and clinical implication of variability in platelet response to aspirin and clopidogrel therapy. Am J Cardiol 2009;104:227-233.
21. Jin RC, Voetsch B, Loscalzo J. Endogenous mechanisms of inhibition of platelet function. Microcirculation 2005;12:247-258.
22. Hawiger J. Platelet secretory pathways: An overview. Methods Enzymol 1989;169:191-195.
23. Golański J, Pietrucha T, Baj Z, Greger J, Watala C. Molecular insights into the anticoagulant-induced spontaneous activation of platelets in whole blood-various anticoagulants are not equal. Thromb Res 1996;83:199-216.
24. Glusa E. Platelet aggregation in recombinant-hirudinanticoagulated blood. Haemostasis 1991;21(Suppl 1): 116-120.
25. Cardinal D, Flower R. The electronic aggregometer: A novel device for assessing platelet behavior in blood. J Pharmacol Meth 1980;3:135-158.
26. McGlasson DL, Fritsma GA. Whole blood platelet aggregometry and platelet function testing. Semin Thromb Hemost 2009;35:168-180.
27. Gorog DA, Sweeny JM, Fuster V. Antiplatelet drug 'resistance'. Part 2: Laboratory resistance to antiplatelet drugs-fact or artifact? Nat Rev Cardiol 2009;6:365-373.
28. Wallén N, Ladjevardi M, Albert J, Bröijersén A. Influence of different anticoagulants on platelet aggregation in whole blood; a comparison between citrate, low molecular mass heparin and hirudin. Thromb Res 1997;87:151-157.
29. Edwards A, Jakubowski JA, Rechner AR, Sugidachi A, Harrison P. Evaluation of the INNOVANCE PFA P2Y test cartridge: Sensitivity to P2Y(12) blockade and influence of anticoagulant. Platelets 2011 Aug 17. [Epub ahead of print], (DOI:10.3109/09537104.2011.601361).
30. Izaguirre G, Swanson R, Raja SM, Rezaie AR, Olson ST. Mechanism by which exosites promote the inhibition of blood coagulation proteases by heparin-activated antithrombin. J Biol Chem 2007;282:33609-33622.
31. Lindhout T, Blezer R, Hemker H. The anticoagulant mechanism of action of recombinant hirudin (CGP 39393) in plasma. Thromb Haemost 1990;64:464-468.
32. Kaiser B, Fareed J, Walenga J, Hoppensteadt D, Markwardt F. In vitro studies on thrombin generation in citrated, r-hirudinized and heparinized whole blood. Thromb Res 1991;64:589-596.
33. Schneider D, Tracy P, Mann K, Sobel B. Differential effects of anticoagulants on the activation of platelets ex vivo. Circulation 1997;96:2877-2883.
34. Harrison P. Assessment of platelet function in the laboratory. Hamostaseologie 2009;29:25-31.
35. Scharbert G, Kalb M, Marschalek C, Kozek-Langenecker S. The effects of test temperature and storage temperature on platelet aggregation: A whole blood in vitro study. Anesth Analg 2006;102:1280-1284.
36. Anderson ER, Foulks JG. Competitive inhibition by lithium and hydrogen ions of the effect of calcium on the aggregation of rabbit platelets. Thromb Haemost 1976;36:343-359.
37. de Meis L, Suzano VA. Uncoupling of muscle and blood platelets Ca2+ transport ATPases by heparin. Regulation by K+. J Biol Chem 1994;269:14525- 14529.
38. Kuliczkowski W, Witkowski A, Polonski L, Watala C, Filipiak K, Budaj A, Golanski J, Sitkiewicz D, Pregowski J, Gorski J, et al. Interindividual variability in the response to oral antiplatelet drugs: A position paper of the Working Group on antiplatelet drugs resistance appointed by the Section of Cardiovascular Interventions of the Polish Cardiac Society, endorsed by the Working Group on Thrombosis of the European Society of Cardiology. Eur Heart J 2009;30: 426-435.
39. Ho C, Chan I. The influence of time of storage, temperature of storage, platelet number in platelet-rich plasma, packed cell, mean platelet volume, hemoglobin concentration, age, and sex on platelet aggregation test. Ann Hematol 1995;71:129-133.
40. Bolliger D, Seeberger M, Tanaka K, Dell-Kuster S, Gregor M, Zenklusen U, Grapow M, Tsakiris D, Filipovic M. Pre-analytical effects of pneumatic tube transport on impedance platelet aggregometry. Platelets 2009;20: 458-465.
41. Savion N, Shenkman B, Tamarin I, Dardik R, Frojmovic M, Varon D. Transient adhesion refractoriness of circulating platelets under shear stress: The role of partial activation and microaggregate formation by suboptimal ADP concentration. Br J Haematol 2001;112:1055-1061.
42. Scharbert G, Kalb ML, Essmeister R, Kozek-Langenecker SA. Mild and moderate hypothermia increases platelet aggregation induced by various agonists: A whole blood in vitro study. Platelets 2010;21:44-48.