Footprint of positive selection in treponema pallidum subsp. pallidum genome sequences suggests adaptive microevolution of the syphilis pathogen

PLoS Neglected Tropical Diseases

Volumn 6, Issue 6, 2012, Pages

  Giacani, Lorenzo ^a   Chattopadhyay, Sujay ^a   Centurion Lara, Arturo ^a   Jeffrey, Brendan M ^b   Le, Hoavan T ^a   Molini, Barbara J ^a   Lukehart, Sheila A ^a   Sokurenko, Evgeni V ^a   Rockey, Daniel D ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b OREGON STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; GENE INSERTION; GENE LOCUS; GENE SEQUENCE; GENOME; INDEL MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; RABBIT; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SINGLE NUCLEOTIDE POLYMORPHISM; SYPHILIS; TREPONEMA PALLIDUM; ADAPTATION; ANIMAL; BACTERIAL GENOME; BIOLOGY; CLASSIFICATION; COMPARATIVE STUDY; DISEASE MODEL; DNA SEQUENCE; GENETIC SELECTION; GENETICS; HUMAN; MICROBIOLOGY; MOLECULAR EVOLUTION; MOLECULAR GENETICS; SEQUENCE HOMOLOGY;

BACTERIAL DNA;

ADAPTATION, BIOLOGICAL; ANIMALS; BASE SEQUENCE; COMPUTATIONAL BIOLOGY; DISEASE MODELS, ANIMAL; DNA, BACTERIAL; EVOLUTION, MOLECULAR; GENOME, BACTERIAL; HUMANS; MOLECULAR SEQUENCE DATA; POLYMORPHISM, SINGLE NUCLEOTIDE; RABBITS; SELECTION, GENETIC; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, NUCLEIC ACID; SYPHILIS; TREPONEMA PALLIDUM;

EID: 84863703072     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0001698     Document Type: Article

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