-
1
-
-
0017163222
-
Connectin, an elastic protein from myofibrils
-
Maruyama K. Connectin, an elastic protein from myofibrils. J Biochem. 1976;80:405-407.
-
(1976)
J Biochem
, vol.80
, pp. 405-407
-
-
Maruyama, K.1
-
3
-
-
0035941407
-
The complete gene sequence of titin, expression of an unusual 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system
-
Bang ML, Centner T, Fornoff F, Geach AJ, Gotthardt M, McNabb M, Witt CC, Labeit D, Gregorio CC, Granzier H, Labeit S. The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system. Circ Res. 2001;89:1065-1072. (Pubitemid 34640875)
-
(2001)
Circulation Research
, vol.89
, Issue.11
, pp. 1065-1072
-
-
Bang, M.-L.1
Centner, T.2
Fornoff, F.3
Geach, A.J.4
Gotthardt, M.5
McNabb, M.6
Witt, C.C.7
Labeit, D.8
Gregorio, C.C.9
Granzier, H.10
Labeit, S.11
-
4
-
-
0023047016
-
A physiological role for titin and nebulin in skeletal muscle
-
Horowits R, Kempner ES, Bisher ME, Podolsky RJ. A physiological role for titin and nebulin in skeletal muscle. Nature. 1986;323:160-164. (Pubitemid 16024963)
-
(1986)
Nature
, vol.322
, Issue.6084
, pp. 160-164
-
-
Horowits, R.1
Kempner, E.S.2
Bisher, M.E.3
Podolsky, R.J.4
-
5
-
-
0027934071
-
Passive and active tension in single cardiac myofibrils
-
Linke WA, Popov VI, Pollack GH. Passive and active tension in single cardiac myofibrils. Biophys J. 1994;67:782-792. (Pubitemid 24235407)
-
(1994)
Biophysical Journal
, vol.67
, Issue.2
, pp. 782-792
-
-
Linke, W.A.1
Popov, V.I.2
Pollack, G.H.3
-
6
-
-
0034509442
-
Changes in titin and collagen underlie diastolic stiffness diversity of cardiac muscle
-
Wu Y, Cazorla O, Labeit D, Labeit S, Granzier H. Changes in titin and collagen underlie diastolic stiffness diversity of cardiac muscle. J Mol Cell Cardiol. 2000;32:2151-2162.
-
(2000)
J Mol Cell Cardiol
, vol.32
, pp. 2151-2162
-
-
Wu, Y.1
Cazorla, O.2
Labeit, D.3
Labeit, S.4
Granzier, H.5
-
7
-
-
0028824480
-
Titins: Giant proteins in charge of muscle ultrastructure and elasticity
-
Labeit S, Kolmerer B. Titins: giant proteins in charge of muscle ultrastructure and elasticity. Science. 1995;270:293-296.
-
(1995)
Science
, vol.270
, pp. 293-296
-
-
Labeit, S.1
Kolmerer, B.2
-
8
-
-
0035947754
-
Titin-based modulation of calcium sensitivity of active tension in mouse skinned cardiac myocytes
-
Cazorla O, Wu Y, Irving TC, Granzier H. Titin-based modulation of calcium sensitivity of active tension in mouse skinned cardiac myocytes. Circ Res. 2001;88:1028-1035. (Pubitemid 34137115)
-
(2001)
Circulation Research
, vol.88
, Issue.10
, pp. 1028-1035
-
-
Cazorla, O.1
Wu, Y.2
Irving, T.C.3
Granzier, H.4
-
9
-
-
79953178205
-
The giant protein titin: A regulatory node that integrates myocyte signaling pathways
-
Kruger M, Linke WA. The giant protein titin: a regulatory node that integrates myocyte signaling pathways. J Biol Chem. 2011;286: 9905-9912.
-
(2011)
J Biol Chem
, vol.286
, pp. 9905-9912
-
-
Kruger, M.1
Linke, W.A.2
-
10
-
-
70349670977
-
Muscle giants: Molecular scaffolds in sarcomerogenesis
-
Kontrogianni-Konstantopoulos A, Ackermann MA, Bowman AL, Yap SV, Bloch RJ. Muscle giants: molecular scaffolds in sarcomerogenesis. Physiol Rev. 2009;89:1217-1267.
-
(2009)
Physiol Rev
, vol.89
, pp. 1217-1267
-
-
Kontrogianni-Konstantopoulos, A.1
Ackermann, M.A.2
Bowman, A.L.3
Yap, S.V.4
Bloch, R.J.5
-
11
-
-
1442323725
-
The sensitive giant: The role of titin-based stretch sensing complexes in the heart
-
DOI 10.1016/j.tcb.2004.01.003, PII S0962892404000224
-
Miller MK, Granzier H, Ehler E, Gregorio CC. The sensitive giant: the role of titin-based stretch sensing complexes in the heart. Trend Cell Biol. 2004;14:119-126. (Pubitemid 38293454)
-
(2004)
Trends in Cell Biology
, vol.14
, Issue.3
, pp. 119-126
-
-
Miller, M.K.1
Granzier, H.2
Ehler, E.3
Gregorio, C.C.4
-
12
-
-
20644440418
-
Cell biology: The kinase domain of titin controls muscle gene expression and protein turnover
-
DOI 10.1126/science.1110463
-
Lange S, Xiang F, Yakovenko A, et al. The kinase domain of titin controls muscle gene expression and protein turnover. Science. 2005;308: 1599-1603. (Pubitemid 40807503)
-
(2005)
Science
, vol.308
, Issue.5728
, pp. 1599-1603
-
-
Lange, S.1
Xiang, F.2
Yakovenko, A.3
Vihola, A.4
Hackman, P.5
Rostkova, E.6
Kristensen, J.7
Brandmeier, B.8
Franzen, G.9
Hedberg, B.10
Gunnarsson, L.G.11
Hughes, S.M.12
Marchand, S.13
Sejersen, T.14
Richard, I.15
Edstrom, L.16
Ehler, E.17
Udd, B.18
Gautel, M.19
-
13
-
-
51649101588
-
Mechanoenzymatics of titin kinase
-
Puchner EM, Alexandrovich A, Kho AL, Hensen U, Schafer LV, Brandmeier B, Grater F, Grubmuller H, Gaub HE, Gautel M. Mechanoenzymatics of titin kinase. Proc Nat Acad Sci. 2008;105:13385-13390.
-
(2008)
Proc Nat Acad Sci
, vol.105
, pp. 13385-13390
-
-
Puchner, E.M.1
Alexandrovich, A.2
Kho, A.L.3
Hensen, U.4
Schafer, L.V.5
Brandmeier, B.6
Grater, F.7
Grubmuller, H.8
Gaub, H.E.9
Gautel, M.10
-
14
-
-
0036723943
-
Tibial muscular dystrophy is a titinopathy caused by mutations in TTN, the gene encoding the giant skeletal-muscle protein titin
-
DOI 10.1086/342380
-
Hackman P, Vihola A, Haravuori H, Marchand S, Sarparanta J, De Seze J, Labeit S, Witt C, Peltonen L, Richard I, Udd B. Tibial muscular dystrophy is a titinopathy caused by mutations in TTN, the gene encoding the giant skeletal-muscle protein titin. Am J Hum Genet. 2002;71: 492-500. (Pubitemid 34970121)
-
(2002)
American Journal of Human Genetics
, vol.71
, Issue.3
, pp. 492-500
-
-
Hackman, P.1
Vihola, A.2
Haravuori, H.3
Marchand, S.4
Sarparanta, J.5
De Seze, J.6
Labeit, S.7
Witt, C.8
Peltonen, L.9
Richard, I.10
Udd, B.11
-
15
-
-
0042845863
-
Tibial muscular dystrophy in a Belgian family
-
DOI 10.1002/ana.10647
-
Van den Bergh PY, Bouquiaux O, Verellen C, Marchand S, Richard I, Hackman P, Udd B. Tibial muscular dystrophy in a Belgian family. Ann Neurol. 2003;54:248-251. (Pubitemid 36909625)
-
(2003)
Annals of Neurology
, vol.54
, Issue.2
, pp. 248-251
-
-
Van Den Bergh, P.Y.K.1
Bouquiaux, O.2
Verellen, C.3
Marchand, S.4
Richard, I.5
Hackman, P.6
Udd, B.7
-
16
-
-
84863116641
-
Truncations of titin causing dilated cardiomyopathy
-
Herman DS, Lam L, Taylor MR, et al. Truncations of titin causing dilated cardiomyopathy. N Engl J Med. 2012;366:619-628.
-
(2012)
N Engl J Med.
, vol.366
, pp. 619-628
-
-
Herman, D.S.1
Lam, L.2
Taylor, M.R.3
-
17
-
-
84860498637
-
Genetics of hypertrophic and dilated cardiomyopathy
-
Jan 20 [Epub ahead of print]. PMID: 22280421
-
Friedrich FW, Carrier L. Genetics of hypertrophic and dilated cardiomyopathy. Curr Pharm Biotechnol. 2012 Jan 20 [Epub ahead of print]. PMID: 22280421.
-
(2012)
Curr Pharm Biotechnol
-
-
Friedrich, F.W.1
Carrier, L.2
-
18
-
-
0033514986
-
Familial dilated cardiomyopathy locus maps to chromosome 2q31
-
Siu BL, Niimura H, Osborne JA, Fatkin D, MacRae C, Solomon S, Benson DW, Seidman JG, Seidman CE. Familial dilated cardiomyopathy locus maps to chromosome 2q31. Circulation. 1999;99:1022-1026. (Pubitemid 29104491)
-
(1999)
Circulation
, vol.99
, Issue.8
, pp. 1022-1026
-
-
Siu, B.L.1
Niimura, H.2
Osborne, J.A.3
Fatkin, D.4
MacRae, C.5
Solomon, S.6
Benson, D.W.7
Seidman, J.G.8
Seidman, C.E.9
-
19
-
-
0036478897
-
Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy
-
Gerull B, Gramlich M, Atherton J, McNabb M, Trombitas K, Sasse-Klaassen S, Seidman JG, Seidman C, Granzier H, Labeit S, Frenneaux M, Thierfelder L. Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy. Nat Genet. 2002;30:201-204.
-
(2002)
Nat Genet
, vol.30
, pp. 201-204
-
-
Gerull, B.1
Gramlich, M.2
Atherton, J.3
McNabb, M.4
Trombitas, K.5
Sasse-Klaassen, S.6
Seidman, J.G.7
Seidman, C.8
Granzier, H.9
Labeit, S.10
Frenneaux, M.11
Thierfelder, L.12
-
20
-
-
33744495726
-
Identification of a novel frameshift mutation in the giant muscle filament titin in a large Australian family with dilated cardiomyopathy
-
DOI 10.1007/s00109-006-0060-6
-
Gerull B, Atherton J, Geupel A, Sasse-Klaassen S, Heuser A, Frenneaux M, McNabb M, Granzier H, Labeit S, Thierfelder L. Identification of a novel frameshift mutation in the giant muscle filament titin in a large Australian family with dilated cardiomyopathy. J Mol Med. 2006;84: 478-483. (Pubitemid 43801326)
-
(2006)
Journal of Molecular Medicine
, vol.84
, Issue.6
, pp. 478-483
-
-
Gerull, B.1
Atherton, J.2
Geupel, A.3
Sasse-Klaassen, S.4
Heuser, A.5
Frenneaux, M.6
McNabb, M.7
Granzier, H.8
Labeit, S.9
Thierfelder, L.10
-
21
-
-
80052565758
-
The cell biology of disease: Cellular mechanisms of cardiomyopathy
-
Harvey PA, Leinwand LA. The cell biology of disease: cellular mechanisms of cardiomyopathy. J Cell Biol. 2011;194:355-365.
-
(2011)
J Cell Biol.
, vol.194
, pp. 355-365
-
-
Harvey, P.A.1
Leinwand, L.A.2
-
22
-
-
67650738888
-
Stress-induced dilated cardiomyopathy in a knock-in mouse model mimicking human titin-based disease
-
Gramlich M, Michely B, Krohne C, Heuser A, Erdmann B, Klaassen S, Hudson B, Magarin M, Kirchner F, Todiras M, Granzier H, Labeit S, Thierfelder L, Gerull B. Stress-induced dilated cardiomyopathy in a knock-in mouse model mimicking human titin-based disease. J Mol Cell Cardiol. 2009;47:352-358.
-
(2009)
J Mol Cell Cardiol
, vol.47
, pp. 352-358
-
-
Gramlich, M.1
Michely, B.2
Krohne, C.3
Heuser, A.4
Erdmann, B.5
Klaassen, S.6
Hudson, B.7
Magarin, M.8
Kirchner, F.9
Todiras, M.10
Granzier, H.11
Labeit, S.12
Thierfelder, L.13
Gerull, B.14
-
23
-
-
33646798022
-
M line-deficient titin causes cardiac lethality through impaired maturation of the sarcomere
-
DOI 10.1083/jcb.200601014
-
Weinert S, Bergmann N, Luo X, Erdmann B, Gotthardt M. M linedeficient titin causes cardiac lethality through impaired maturation of the sarcomere. J Cell Biol. 2006;173:559-570. (Pubitemid 43765202)
-
(2006)
Journal of Cell Biology
, vol.173
, Issue.4
, pp. 559-570
-
-
Weinert, S.1
Bergmann, N.2
Luo, X.3
Erdmann, B.4
Gotthardt, M.5
-
24
-
-
4344598187
-
Muscle-specific RING finger-2 (MURF-2) is important for microtubule, intermediate filament and sarcomeric M-line maintenance in striated muscle development
-
DOI 10.1242/jcs.01158
-
McElhinny AS, Perry CN, Witt CC, Labeit S, Gregorio CC. Musclespecific RING finger-2 (MURF-2) is important for microtubule, intermediate filament and sarcomeric M-line maintenance in striated muscle development. J Cell Sci. 2004;117:3175-3188. (Pubitemid 39139904)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.15
, pp. 3175-3188
-
-
McElhinny, A.S.1
Perry, C.N.2
Witt, C.C.3
Labeit, S.4
Gregorio, C.C.5
|