메뉴 건너뛰기




Volumn 27, Issue 4, 2012, Pages 267-279

A genetic instrument for Mendelian randomization of fibrinogen

Author keywords

Fibrinogen gene; Haplotypes; Mendelian randomization; Tagging SNPs

Indexed keywords

FIBRINOGEN;

EID: 84863663919     PISSN: 03932990     EISSN: 15737284     Source Type: Journal    
DOI: 10.1007/s10654-012-9666-x     Document Type: Article
Times cited : (13)

References (57)
  • 1
    • 84926426742 scopus 로고    scopus 로고
    • Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: An individual participant meta-analysis
    • Danesh J, Lewington S, Thompson SG, et al. Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: An individual participant meta-analysis. JAMA. 2005;294(14):1799-809.
    • (2005) JAMA , vol.294 , Issue.14 , pp. 1799-809
    • Danesh, J.1    Lewington, S.2    Thompson, S.G.3
  • 2
    • 0000751868 scopus 로고
    • Evolution and organization of the fibrinogen locus on chromosome 4: Gene duplication accompanied by transposition and inversion
    • Kant JA, Fornace AJ Jr, Saxe D, Simon MI, McBride OW, Crabtree GR. Evolution and organization of the fibrinogen locus on chromosome 4: Gene duplication accompanied by transposition and inversion. Proc Natl Acad Sci USA. 1985;82(8):2344-8.
    • (1985) Proc Natl Acad Sci USA. , vol.82 , Issue.8 , pp. 2344-8
    • Kant, J.A.1    Fornace Jr., A.J.2    Saxe, D.3    Simon, M.I.4    McBride, O.W.5    Crabtree, G.R.6
  • 3
    • 0028958950 scopus 로고
    • Genetic and environmental sources of fibrinogen variability in Israeli families: The Kibbutzim Family Study
    • Friedlander Y, Elkana Y, Sinnreich R, Kark JD. Genetic and environmental sources of fibrinogen variability in Israeli families: The Kibbutzim Family Study. Am J Hum Genet. 1995;56(5): 1194-206.
    • (1995) Am J Hum Genet. , vol.56 , Issue.5 , pp. 1194-206
    • Friedlander, Y.1    Elkana, Y.2    Sinnreich, R.3    Kark, J.D.4
  • 4
    • 0023255622 scopus 로고
    • Role of genetic variation at the fibrinogen locus in determination of plasma fibrinogen concentrations
    • 8548
    • Humphries SE, Cook M, Dubowitz M, Stirling Y, Meade TW. Role of genetic variation at the fibrinogen locus in determination of plasma fibrinogen concentrations. Lancet. 1987;1(8548):1452-5.
    • (1987) Lancet. , vol.1 , pp. 1452-5
    • Humphries, S.E.1    Cook, M.2    Dubowitz, M.3    Stirling, Y.4    Meade, T.W.5
  • 5
    • 0031836563 scopus 로고    scopus 로고
    • 455G/A polymorphism of the beta-fibrinogen gene is associated with the progression of coronary atherosclerosis in symptomatic men: Proposed role for an acute-phase reaction pattern of fibrinogen. REGRESS group
    • de Maat MP, Kastelein JJ, Jukema JW, et al. 455G/A polymorphism of the beta-fibrinogen gene is associated with the progression of coronary atherosclerosis in symptomatic men: Proposed role for an acute-phase reaction pattern of fibrinogen. REGRESS group. Arterioscler Thromb Vasc Biol. 1998;18(2): 265-71.
    • (1998) Arterioscler Thromb Vasc Biol. , vol.18 , Issue.2 , pp. 265-71
    • De Maat, M.P.1    Kastelein, J.J.2    Jukema, J.W.3
  • 8
    • 33748438338 scopus 로고    scopus 로고
    • Fibrinogen and coronary heart disease: Test of causality by 'Mendelian randomization'
    • Keavney B, Danesh J, Parish S, et al. Fibrinogen and coronary heart disease: Test of causality by 'Mendelian randomization'. Int J Epidemiol. 2006;35(4):935-43.
    • (2006) Int J Epidemiol. , vol.35 , Issue.4 , pp. 935-43
    • Keavney, B.1    Danesh, J.2    Parish, S.3
  • 9
    • 1542709218 scopus 로고    scopus 로고
    • Fibrinogen, C-reactive protein and coronary heart disease: Does Mendelian randomization suggest the associations are non-causal?
    • Davey Smith G, Harbord R, Ebrahim S. Fibrinogen, C-reactive protein and coronary heart disease: Does Mendelian randomization suggest the associations are non-causal? QJM. 2004;97(3):163-6.
    • (2004) QJM , vol.97 , Issue.3 , pp. 163-6
    • Davey Smith, G.1    Harbord, R.2    Ebrahim, S.3
  • 10
    • 84871768280 scopus 로고
    • Problems with instrumental variables estimation when the correlation between the instruments and the endogenous explanatory variable is weak
    • Bound J, Jaeger D, Baker R. Problems with instrumental variables estimation when the correlation between the instruments and the endogenous explanatory variable is weak. J Am Stat Assoc. 1995;90(430):443-50.
    • (1995) J Am Stat Assoc. , vol.90 , Issue.430 , pp. 443-50
    • Bound, J.1    Jaeger, D.2    Baker, R.3
  • 11
    • 0346307687 scopus 로고    scopus 로고
    • Instrumental variables regression with weak instruments
    • Staiger D, Stock J. Instrumental variables regression with weak instruments. Econometrica. 1997;65(3):557-86.
    • (1997) Econometrica. , vol.65 , Issue.3 , pp. 557-86
    • Staiger, D.1    Stock, J.2
  • 12
    • 33749631248 scopus 로고    scopus 로고
    • Commentary: Fibrinogen and coronary heart disease-Test of causality by 'Mendelian' randomization by Keavney et al
    • Meade TW, Humphries SE, De Stavola BL. Commentary: Fibrinogen and coronary heart disease-Test of causality by 'Mendelian' randomization by Keavney et al. Int J Epidemiol. 2006;35(4):944-7.
    • (2006) Int J Epidemiol. , vol.35 , Issue.4 , pp. 944-7
    • Meade, T.W.1    Humphries, S.E.2    De Stavola, B.L.3
  • 13
    • 15344343051 scopus 로고    scopus 로고
    • Contribution of haplotypes across the fibrinogen gene cluster to variation in risk of myocardial infarction
    • Mannila MN, Eriksson P, Lundman P, et al. Contribution of haplotypes across the fibrinogen gene cluster to variation in risk of myocardial infarction. Thromb Haemost. 2005;93(3):570-7.
    • (2005) Thromb Haemost. , vol.93 , Issue.3 , pp. 570-7
    • Mannila, M.N.1    Eriksson, P.2    Lundman, P.3
  • 14
    • 28844473918 scopus 로고    scopus 로고
    • Genetic variation in the fibrinogen gamma gene increases the risk for deep venous thrombosis by reducing plasma fibrinogen gamma' levels
    • Uitte de Willige S, de Visser MC, Houwing-Duistermaat JJ, Rosendaal FR, Vos HL, Bertina RM. Genetic variation in the fibrinogen gamma gene increases the risk for deep venous thrombosis by reducing plasma fibrinogen gamma' levels. Blood. 2005;106(13):4176-83.
    • (2005) Blood. , vol.106 , Issue.13 , pp. 4176-83
    • Uitte De Willige, S.1    De Visser, M.C.2    Houwing-Duistermaat, J.J.3    Rosendaal, F.R.4    Vos, H.L.5    Bertina, R.M.6
  • 15
    • 0034610405 scopus 로고    scopus 로고
    • Comparison of novel hemostatic factors and conventional risk factors for prediction of coronary heart disease
    • Cooper JA, Miller GJ, Bauer KA, et al. Comparison of novel hemostatic factors and conventional risk factors for prediction of coronary heart disease. Circulation. 2000;102(23):2816-22.
    • (2000) Circulation. , vol.102 , Issue.23 , pp. 2816-22
    • Cooper, J.A.1    Miller, G.J.2    Bauer, K.A.3
  • 16
    • 0028801727 scopus 로고
    • The effects of quality and timing of venepuncture on markers of blood coagulation in healthy middle-aged men
    • Miller GJ, Bauer KA, Barzegar S, et al. The effects of quality and timing of venepuncture on markers of blood coagulation in healthy middle-aged men. Thromb Haemost. 1995;73(1):82-6.
    • (1995) Thromb Haemost. , vol.73 , Issue.1 , pp. 82-6
    • Miller, G.J.1    Bauer, K.A.2    Barzegar, S.3
  • 17
    • 0029894643 scopus 로고    scopus 로고
    • Increased activation of the haemostatic system in men at high risk of fatal coronary heart disease
    • Miller GJ, Bauer KA, Barzegar S, Cooper JA, Rosenberg RD. Increased activation of the haemostatic system in men at high risk of fatal coronary heart disease. Thromb Haemost. 1996;75(5): 767-71.
    • (1996) Thromb Haemost. , vol.75 , Issue.5 , pp. 767-71
    • Miller, G.J.1    Bauer, K.A.2    Barzegar, S.3    Cooper, J.A.4    Rosenberg, R.D.5
  • 18
    • 33745551242 scopus 로고
    • Rapid physiological coagulation method in determination of fibrinogen
    • Clauss A. Rapid physiological coagulation method in determination of fibrinogen. Acta Haematol. 1957;17(4):237-46.
    • (1957) Acta Haematol. , vol.17 , Issue.4 , pp. 237-46
    • Clauss, A.1
  • 21
    • 66149086142 scopus 로고    scopus 로고
    • Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk
    • Drenos F, Talmud PJ, Casas JP, et al. Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk. Hum Mol Genet. 2009;18(12):2305-16.
    • (2009) Hum Mol Genet. , vol.18 , Issue.12 , pp. 2305-16
    • Drenos, F.1    Talmud, P.J.2    Casas, J.P.3
  • 23
    • 0027954567 scopus 로고
    • Linkage disequilibrium across the fibrinogen locus as shown by five genetic polymorphisms G/A-455 (HaeIII) C/T-148 (HindIII/AluI) T/G ? 1689 (AvaII) and BclI (beta-fibrinogen) and TaqI (alphafibrinogen) and their detection by PCR
    • Thomas A, Lamlum H, Humphries S, Green F. Linkage disequilibrium across the fibrinogen locus as shown by five genetic polymorphisms, G/A-455 (HaeIII), C/T-148 (HindIII/AluI), T/G ? 1689 (AvaII), and BclI (beta-fibrinogen) and TaqI (alphafibrinogen), and their detection by PCR. Hum Mutat. 1994;3(1): 79-81.
    • (1994) Hum Mutat. , vol.3 , Issue.1 , pp. 79-81
    • Thomas, A.1    Lamlum, H.2    Humphries, S.3    Green, F.4
  • 24
    • 0028037913 scopus 로고
    • Linkage disequilibrium relationships among four polymorphisms within the human fibrinogen gene cluster
    • Baumann RE, Henschen AH. Linkage disequilibrium relationships among four polymorphisms within the human fibrinogen gene cluster. Hum Genet. 1994;94(2):165-70.
    • (1994) Hum Genet. , vol.94 , Issue.2 , pp. 165-70
    • Baumann, R.E.1    Henschen, A.H.2
  • 25
    • 18444371186 scopus 로고    scopus 로고
    • Cohort profile: The whitehall II study
    • Marmot M, Brunner E. Cohort profile: The whitehall II study. Int J Epidemiol. 2005;34(2):251-6.
    • (2005) Int J Epidemiol. , vol.34 , Issue.2 , pp. 251-6
    • Marmot, M.1    Brunner, E.2
  • 26
    • 72149100752 scopus 로고    scopus 로고
    • Gene-centric association signals for lipids and apolipoproteins identified via the Human- CVD BeadChip
    • Talmud PJ, Drenos F, Shah S, et al. Gene-centric association signals for lipids and apolipoproteins identified via the Human- CVD BeadChip. Am J Hum Genet. 2009;85(5):628-42.
    • (2009) Am J Hum Genet. , vol.85 , Issue.5 , pp. 628-42
    • Talmud, P.J.1    Drenos, F.2    Shah, S.3
  • 27
    • 0037855767 scopus 로고    scopus 로고
    • Lack of association between depressive symptoms and markers of immune and vascular inflammation in middle-aged men and women
    • Steptoe A, Kunz-Ebrecht SR, Owen N. Lack of association between depressive symptoms and markers of immune and vascular inflammation in middle-aged men and women. Psychol Med. 2003;33(4):667-74.
    • (2003) Psychol Med. , vol.33 , Issue.4 , pp. 667-74
    • Steptoe, A.1    Kunz-Ebrecht, S.R.2    Owen, N.3
  • 28
    • 56349155783 scopus 로고    scopus 로고
    • Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies
    • Keating BJ, Tischfield S, Murray SS, et al. Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. PLoS ONE. 2008;3(10):e3583.
    • (2008) PLoS ONE. , vol.3 , Issue.10
    • Keating, B.J.1    Tischfield, S.2    Murray, S.S.3
  • 29
    • 0035071957 scopus 로고    scopus 로고
    • A new statistical method for haplotype reconstruction from population data
    • Stephens M, Smith NJ, Donnelly P. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet. 2001;68(4):978-89.
    • (2001) Am J Hum Genet. , vol.68 , Issue.4 , pp. 978-89
    • Stephens, M.1    Smith, N.J.2    Donnelly, P.3
  • 30
    • 13844270527 scopus 로고    scopus 로고
    • Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation
    • Stephens M, Scheet P. Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation. Am J Hum Genet. 2005;76(3):449-62.
    • (2005) Am J Hum Genet. , vol.76 , Issue.3 , pp. 449-62
    • Stephens, M.1    Scheet, P.2
  • 31
    • 17944370141 scopus 로고    scopus 로고
    • Genetic linkage and transmission disequilibrium of marker haplotypes at chromosome 1q41 in human systemic lupus erythematosus
    • Graham RR, Langefeld CD, Gaffney PM, et al. Genetic linkage and transmission disequilibrium of marker haplotypes at chromosome 1q41 in human systemic lupus erythematosus. Arthritis Res. 2001;3(5):299-305.
    • (2001) Arthritis Res. , vol.3 , Issue.5 , pp. 299-305
    • Graham, R.R.1    Langefeld, C.D.2    Gaffney, P.M.3
  • 32
    • 33344458848 scopus 로고    scopus 로고
    • A comparison of phasing algorithms for trios and unrelated individuals
    • Marchini J, Cutler D, Patterson N, et al. A comparison of phasing algorithms for trios and unrelated individuals. Am J Hum Genet. 2006;78(3):437-50.
    • (2006) Am J Hum Genet. , vol.78 , Issue.3 , pp. 437-50
    • Marchini, J.1    Cutler, D.2    Patterson, N.3
  • 33
    • 0242691208 scopus 로고    scopus 로고
    • A comparison of bayesian methods for haplotype reconstruction from population genotype data
    • Stephens M, Donnelly P. A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet. 2003;73(5):1162-9.
    • (2003) Am J Hum Genet. , vol.73 , Issue.5 , pp. 1162-9
    • Stephens, M.1    Donnelly, P.2
  • 34
    • 67749102677 scopus 로고    scopus 로고
    • Correcting for multivariate measurement error by regression calibration in meta-analyses of epidemiological studies
    • Wood AM, White IR, Thompson SG, et al. Correcting for multivariate measurement error by regression calibration in meta-analyses of epidemiological studies. Stat Med. 2009;28(7):1067-92.
    • (2009) Stat Med. , vol.28 , Issue.7 , pp. 1067-92
    • Wood, A.M.1    White, I.R.2    Thompson, S.G.3
  • 36
    • 33748804424 scopus 로고    scopus 로고
    • A tutorial on statistical methods for population association studies
    • Balding DJ. A tutorial on statistical methods for population association studies. Nat Rev Genet. 2006;7(10):781-91.
    • (2006) Nat Rev Genet. , vol.7 , Issue.10 , pp. 781-91
    • Balding, D.J.1
  • 37
    • 40849083720 scopus 로고    scopus 로고
    • Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology
    • Lawlor DA, Harbord RM, Sterne JA, Timpson N, Davey Smith G. Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology. Stat Med. 2008;27(8): 1133-63.
    • (2008) Stat Med. , vol.27 , Issue.8 , pp. 1133-63
    • Lawlor, D.A.1    Harbord, R.M.2    Sterne, J.A.3    Timpson, N.4    Davey Smith, G.5
  • 39
    • 79954605539 scopus 로고    scopus 로고
    • Using genetic loci to understand the relationship between adiposity and psychological distress: A Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults
    • Lawlor DA, Harbord RM, Tybjaerg-Hansen A et al. Using genetic loci to understand the relationship between adiposity and psychological distress: A Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults. J Intern Med. 2011;269:525-37.
    • (2011) J Intern Med. , vol.269 , pp. 525-37
    • Lawlor, D.A.1    Harbord, R.M.2    Tybjaerg-Hansen, A.3
  • 40
    • 77957745583 scopus 로고    scopus 로고
    • Application of statistical and functional methodologies for the investigation of genetic determinants of coronary heart disease biomarkers: Lipoprotein lipase genotype and plasma triglycerides as an exemplar
    • Smith AJ, Palmen J, Putt W, Talmud PJ, Humphries SE, Drenos F. Application of statistical and functional methodologies for the investigation of genetic determinants of coronary heart disease biomarkers: Lipoprotein lipase genotype and plasma triglycerides as an exemplar. Hum Mol Genet. 2010;19(20):3936-47.
    • (2010) Hum Mol Genet. , vol.19 , Issue.20 , pp. 3936-47
    • Smith, A.J.1    Palmen, J.2    Putt, W.3    Talmud, P.J.4    Humphries, S.E.5    Drenos, F.6
  • 42
    • 0035257236 scopus 로고    scopus 로고
    • Association study designs for complex diseases
    • Cardon LR, Bell JI. Association study designs for complex diseases. Nat Rev Genet. 2001;2(2):91-9.
    • (2001) Nat Rev Genet. , vol.2 , Issue.2 , pp. 91-9
    • Cardon, L.R.1    Bell, J.I.2
  • 43
    • 0037426052 scopus 로고    scopus 로고
    • Problems of reporting genetic associations with complex outcomes
    • Colhoun HM, McKeigue PM, Davey Smith G, et al. Problems of reporting genetic associations with complex outcomes. Lancet. 2003;361(9360):865-72.
    • (2003) Lancet. , vol.361 , Issue.9360 , pp. 865-72
    • Colhoun, H.M.1    McKeigue, P.M.2    Davey Smith, G.3
  • 44
    • 0035922669 scopus 로고    scopus 로고
    • Epidemiological methods for studying genes and environmental factors in complex diseases
    • Clayton D, McKeigue PM. Epidemiological methods for studying genes and environmental factors in complex diseases. Lancet. 2001;358(9290):1356-60.
    • (2001) Lancet. , vol.358 , Issue.9290 , pp. 1356-60
    • Clayton, D.1    McKeigue, P.M.2
  • 45
    • 28444437027 scopus 로고    scopus 로고
    • An evaluation of HapMap sample size and tagging SNP performance in large-scale empirical and simulated data sets
    • Zeggini E, Rayner W, Morris AP, et al. An evaluation of HapMap sample size and tagging SNP performance in large-scale empirical and simulated data sets. Nat Genet. 2005;37(12):1320-2.
    • (2005) Nat Genet. , vol.37 , Issue.12 , pp. 1320-2
    • Zeggini, E.1    Rayner, W.2    Morris, A.P.3
  • 46
    • 0037994180 scopus 로고    scopus 로고
    • Assessing the impact of biobanks
    • Cambon-Thomsen A. Assessing the impact of biobanks. Nat Genet. 2003;34(1):25-6.
    • (2003) Nat Genet. , vol.34 , Issue.1 , pp. 25-6
    • Cambon-Thomsen, A.1
  • 47
    • 0027428484 scopus 로고
    • Human fibrinogen polymorphic site analysis by restriction endonuclease digestion and allele-specific polymerase chain reaction amplification: Identification of polymorphisms at positions A alpha 312 and B beta 448
    • Baumann RE, Henschen AH. Human fibrinogen polymorphic site analysis by restriction endonuclease digestion and allele-specific polymerase chain reaction amplification: Identification of polymorphisms at positions A alpha 312 and B beta 448. Blood. 1993;82(7):2117-24.
    • (1993) Blood. , vol.82 , Issue.7 , pp. 2117-24
    • Baumann, R.E.1    Henschen, A.H.2
  • 48
    • 33646800836 scopus 로고    scopus 로고
    • Association between patterns of nucleotide variation across the three fibrinogen genes and plasma fibrinogen levels: The Coronary Artery Risk Development in Young Adults (CARDIA) study
    • Reiner AP, Carty CL, Carlson CS, et al. Association between patterns of nucleotide variation across the three fibrinogen genes and plasma fibrinogen levels: The Coronary Artery Risk Development in Young Adults (CARDIA) study. J Thromb Haemost. 2006;4(6):1279-87.
    • (2006) J Thromb Haemost. , vol.4 , Issue.6 , pp. 1279-87
    • Reiner, A.P.1    Carty, C.L.2    Carlson, C.S.3
  • 50
    • 38949156646 scopus 로고    scopus 로고
    • Associations between common fibrinogen gene polymorphisms and cardiovascular disease in older adults. The Cardiovascular Health Study
    • Carty CL, Cushman M, Jones D, et al. Associations between common fibrinogen gene polymorphisms and cardiovascular disease in older adults. The Cardiovascular Health Study. Thromb Haemost. 2008;99(2):388-95.
    • (2008) Thromb Haemost. , vol.99 , Issue.2 , pp. 388-95
    • Carty, C.L.1    Cushman, M.2    Jones, D.3
  • 51
    • 1542270282 scopus 로고    scopus 로고
    • Combined segregation and linkage analysis of fibrinogen variability in Israeli families: Evidence for two quantitative-Trait loci, one of which is linked to a functional variant (-58G[A) in the promoter of the alpha-fibrinogen gene
    • Friedlander Y, Kark JD, Sinnreich R, Basso F, Humphries SE. Combined segregation and linkage analysis of fibrinogen variability in Israeli families: Evidence for two quantitative-Trait loci, one of which is linked to a functional variant (-58G[A) in the promoter of the alpha-fibrinogen gene. Ann Hum Genet. 2003;67(Pt 3):228-41.
    • (2003) Ann Hum Genet. , vol.67 , Issue.PART 3 , pp. 228-41
    • Friedlander, Y.1    Kark, J.D.2    Sinnreich, R.3    Basso, F.4    Humphries, S.E.5
  • 52
    • 0033387742 scopus 로고    scopus 로고
    • Two common, functional polymorphisms in the promoter region of the beta-fibrinogen gene contribute to regulation of plasma fibrinogen concentration
    • van't Hooft FM, von Bahr SJ, Silveira A, Iliadou A, Eriksson P, Hamsten A. Two common, functional polymorphisms in the promoter region of the beta-fibrinogen gene contribute to regulation of plasma fibrinogen concentration. Arterioscler Thromb Vasc Biol. 1999;19(12):3063-70.
    • (1999) Arterioscler Thromb Vasc Biol. , vol.19 , Issue.12 , pp. 3063-70
    • Van't Hooft, F.M.1    Von Bahr, S.J.2    Silveira, A.3    Iliadou, A.4    Eriksson, P.5    Hamsten, A.6
  • 53
    • 9044240867 scopus 로고    scopus 로고
    • Beta fibrinogen gene polymorphisms are associated with plasma fibrinogen and coronary artery disease in patients with myocardial infarction. The ECTIM Study. Etude Cas-Temoins sur l'Infarctus du Myocarde
    • Behague I, Poirier O, Nicaud V, et al. Beta fibrinogen gene polymorphisms are associated with plasma fibrinogen and coronary artery disease in patients with myocardial infarction. The ECTIM Study. Etude Cas-Temoins sur l'Infarctus du Myocarde. Circulation. 1996;93(3):440-9.
    • (1996) Circulation. , vol.93 , Issue.3 , pp. 440-9
    • Behague, I.1    Poirier, O.2    Nicaud, V.3
  • 54
    • 33645542590 scopus 로고    scopus 로고
    • Epistatic and pleiotropic effects of polymorphisms in the fibrinogen and coagulation factor XIII genes on plasma fibrinogen concentration, fibrin gel structure and risk of myocardial infarction
    • Mannila MN, Eriksson P, Ericsson CG, Hamsten A, Silveira A. Epistatic and pleiotropic effects of polymorphisms in the fibrinogen and coagulation factor XIII genes on plasma fibrinogen concentration, fibrin gel structure and risk of myocardial infarction. Thromb Haemost. 2006;95(3):420-7.
    • (2006) Thromb Haemost. , vol.95 , Issue.3 , pp. 420-7
    • Mannila, M.N.1    Eriksson, P.2    Ericsson, C.G.3    Hamsten, A.4    Silveira, A.5
  • 55
    • 33846149334 scopus 로고    scopus 로고
    • The association between fibrinogen haplotypes and myocardial infarction in men is partly mediated through pleiotropic effects on the serum IL-6 concentration
    • Mannila MN, Eriksson P, Leander K, et al. The association between fibrinogen haplotypes and myocardial infarction in men is partly mediated through pleiotropic effects on the serum IL-6 concentration. J Intern Med. 2007;261(2):138-47.
    • (2007) J Intern Med. , vol.261 , Issue.2 , pp. 138-47
    • Mannila, M.N.1    Eriksson, P.2    Leander, K.3
  • 56
    • 33947503976 scopus 로고    scopus 로고
    • Fibrinogen gene haplotypes in relation to risk of coronary events and coronary and extracoronary atherosclerosis: The Rotterdam Study
    • Kardys I, Uitterlinden AG, Hofman A, Witteman JC, de Maat MP. Fibrinogen gene haplotypes in relation to risk of coronary events and coronary and extracoronary atherosclerosis: The Rotterdam Study. Thromb Haemost. 2007;97(2):288-95.
    • (2007) Thromb Haemost. , vol.97 , Issue.2 , pp. 288-95
    • Kardys, I.1    Uitterlinden, A.G.2    Hofman, A.3    Witteman, J.C.4    De Maat, M.P.5
  • 57
    • 77949449452 scopus 로고    scopus 로고
    • Fibrinogen beta variants confer protection against coronary artery disease in a Greek case-control study
    • Theodoraki EV, Nikopensius T, Suhorutsenko J, et al. Fibrinogen beta variants confer protection against coronary artery disease in a Greek case-control study. BMC Med Genet. 2010;11:28.
    • (2010) BMC Med Genet. , Issue.11 , pp. 28
    • Theodoraki, E.V.1    Nikopensius, T.2    Suhorutsenko, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.