CFTR-mediated Cl- transport in the acinar and duct cells of rabbit lacrimal gland

Current Eye Research

Volumn 37, Issue 8, 2012, Pages 671-677

  Lu, Michael ^a   Ding, Chuanqing ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

CFTR; Chloride channel; Dry eye; Lacrimal gland

Indexed keywords

3 BUTYL 1 METHYLXANTHINE; CHLORIDE CHANNEL BLOCKING AGENT; FLUORESCENT DYE; FORSKOLIN; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ACINAR CELL; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CHLORIDE CURRENT; CHLORIDE TRANSPORT; CONFOCAL LASER MICROSCOPY; ELECTROPHYSIOLOGY; EPITHELIUM CELL; EX VIVO STUDY; EXPERIMENTAL RABBIT; FEMALE; LACRIMAL DUCT; LACRIMAL GLAND; LACRIMATION; MULTIPHOTON MICROSCOPY; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN LOCALIZATION; WHOLE CELL;

1-METHYL-3-ISOBUTYLXANTHINE; 4,4'-DIISOTHIOCYANOSTILBENE-2,2'-DISULFONIC ACID; ACINAR CELLS; ANIMALS; BENZOATES; BIOLOGICAL TRANSPORT; CELLS, CULTURED; CHLORIDE CHANNELS; CHLORIDES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EPITHELIAL CELLS; FEMALE; FLUORESCENT DYES; FORSKOLIN; LACRIMAL APPARATUS; MICROSCOPY, CONFOCAL; PATCH-CLAMP TECHNIQUES; PHOSPHODIESTERASE INHIBITORS; RABBITS; THIAZOLIDINES;

EID: 84863659264     PISSN: 02713683     EISSN: 14602202     Source Type: Journal    
DOI: 10.3109/02713683.2012.675613     Document Type: Article

References (47)

1. Noel S, Strale PO, Dannhoffer L et al. Stimulation of salivary secretion in vivo by CFTR potentiators in Cftr+/+ and Cftr-/-mice. J Cyst Fibros 2008;7:128-133.
2. Romanenko VG, Nakamoto T, Catalan MA et al. Clcn2 encodes the hyperpolarization-activated chloride channel in the ducts of mouse salivary glands. Am J Physiol Gastrointest Liver Physiol 2008;295:G1058-G1067.
3. Catalan MA, Nakamoto T, Gonzalez-Begne M et al. Cftr and ENaC ion channels mediate NaCl absorption in the mouse submandibular gland. J Physiol (Lond) 2010;588:713-724.
4. Walcott B, Birzgalis A, Moore LC, Brink PR. Fluid secretion and the Na+-K+-2Cl- cotransporter in mouse exorbital lacrimal gland. Am J Physiol, Cell Physiol 2005;289:C860-C867.
5. Ubels JL, Hoffman HM, Srikanth S, Resau JH, Webb CP. Gene expression in rat lacrimal gland duct cells collected using laser capture microdissection: evidence for K+ secretion by duct cells. Invest Ophthalmol Vis Sci 2006;47:1876-1885.
6. Ding C, Parsa L, Nandoskar P, Zhao P, Wu K, Wang Y. Duct system of the rabbit lacrimal gland: structural characteristics and role in lacrimal secretion. Invest Ophthalmol Vis Sci 2010;51:2960-2967.
7. Durie PR, Kent G, Phillips MJ, Ackerley CA. Characteristic multiorgan pathology of cystic fibrosis in a long-living cystic fibrosis transmembrane regulator knockout murine model. Am J Pathol 2004;164:1481-1493.
8. Ishibashi K, Yamazaki J, Okamura K, Teng Y, Kitamura K, Abe K. Roles of CLCA and CFTR in electrolyte re-absorption from rat saliva. J Dent Res 2006;85:1101-1105.
9. Ishibashi K, Okamura K, Yamazaki J. Involvement of apical P2Y2 receptor-regulated CFTR activity in muscarinic stimulation of Cl(-) reabsorption in rat submandibular gland. Am J Physiol Regul Integr Comp Physiol 2008;294:R1729-R1736.
10. Park HW, Nam JH, Kim JY et al. Dynamic regulation of CFTR bicarbonate permeability by [Cl-]i and its role in pancreatic bicarbonate secretion. Gastroenterology 2010;139:620-631.
11. Gouyer V, Leir SH, Tetaert D et al. The characterization of the first anti-mouse Muc6 antibody shows an increased expression of the mucin in pancreatic tissue of Cftr-knockout mice. Histochem Cell Biol 2010;133:517-525.
12. Ko SB, Mizuno N, Yatabe Y et al. Corticosteroids correct aberrant CFTR localization in the duct and regenerate acinar cells in autoimmune pancreatitis. Gastroenterology 2010;138:1988-1996.
13. Reddy MM, Quinton PM. PKA mediates constitutive activation of CFTR in human sweat duct. J Membr Biol 2009;231:65-78.
14. Brown MB, Haack KK, Pollack BP, Millard-Stafford M, McCarty NA. Low abundance of sweat duct Cl- channel CFTR in both healthy and cystic fibrosis athletes with exceptionally salty sweat during exercise. Am J Physiol Regul Integr Comp Physiol 2011;300:R605-R615.
15. Muhammad E, Leventhal N, Parvari G et al. Autosomal recessive hyponatremia due to isolated salt wasting in sweat associated with a mutation in the active site of Carbonic Anhydrase 12. Hum Genet 2011;129:397-405.
16. Ratcliff R, Evans MJ, Cuthbert AW et al. Production of a severe cystic fibrosis mutation in mice by gene targeting. Nat Genet 1993;4:35-41.
17. Nandoskar P, Wang Y, Wei R et al. Changes of chloride channels in the lacrimal glands of a rabbit model of Sjogren syndrome. Cornea 2012;31:273-279.
18. Jerdeva GV, Wu K, Yarber FA et al. Actin and non-muscle myosin II facilitate apical exocytosis of tear proteins in rabbit lacrimal acinar epithelial cells. J Cell Sci 2005;118:4797-4812.
19. Dinudom A, Young JA, Cook DI. Amiloride-sensitive Na+ current in the granular duct cells of mouse mandibular glands. Pflugers Arch 1993;423:164-166.
20. Peti-Peterdi J, Chambrey R, Bebok Z et al. Macula densa Na(+)/H(+) exchange activities mediated by apical NHE2 and basolateral NHE4 isoforms. Am J Physiol Renal Physiol 2000;278:F452-F463.
21. Nehrke K, Arreola J, Nguyen HV et al. Loss of hyperpolarization-activated Cl(-) current in salivary acinar cells from Clcn2 knockout mice. J Biol Chem 2002;277:23604-23611.
22. Garcia-Olivares J, Alekov A, Boroumand MR, Begemann B, Hidalgo P, Fahlke C. Gating of human ClC-2 chloride channels and regulation by carboxy-terminal domains. J Physiol (Lond) 2008;586:5325-5336.
23. Ma T, Thiagarajah JR, Yang H et al. Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion. J Clin Invest 2002;110:1651-1658.
24. Dartt DA, Moller M, Poulsen JH. Lacrimal gland electrolyte and water secretion in the rabbit: localization and role of (Na+ + K+)-activated ATPase. J Physiol (Lond) 1981;321: 557-569.
25. Mircheff AK. Lacrimal fluid and electrolyte secretion: A review. Curr Eye Res 1989;8:607-617.
26. Herok GH, Millar TJ, Anderton PJ, Martin DK. Characterization of an inwardly rectifying potassium channel in the rabbit superior lacrimal gland. Invest Ophthalmol Vis Sci 1998;39:308-314.
27. Herok GH, Millar TJ, Anderton PJ, Martin DK. Role of chloride channels in regulating the volume of acinar cells of the rabbit superior lacrimal gland. Invest Ophthalmol Vis Sci 2008;49:5517-5525.
28. Selvam S, Thomas PB, Gukasyan HJ et al. Transepithelial bioelectrical properties of rabbit acinar cell monolayers on polyester membrane scaffolds. Am J Physiol, Cell Physiol 2007;293:C1412-C1419.
29. Alexander JH, Van Lennep EW, Young JA. Water and electrolyte secretion by the exorbital lacrimal gland of the rat studied by micropuncture and catheterization techniques. Pflugers Arch 1972;337:299-309.
30. Rismondo V, Osgood TB, Leering P, Hattenhauer MG, Ubels JL, Edelhauser HF. Electrolyte composition of lacrimal gland fluid and tears of normal and vitamin A-deficient rabbits. CLAO J 1989;15:222-228.
31. Quinton PM. Physiological basis of cystic fibrosis: A historical perspective. Physiol Rev 1999;79:S3-S22.
32. Zhang WK, Wang D, Duan Y, Loy MM, Chan HC, Huang P. Mechanosensitive gating of CFTR. Nat Cell Biol 2010;12:507-512.
33. Guo Z, Song D, Azzarolo AM et al. Autologous lacrimal-lymphoid mixed-cell reactions induce dacryoadenitis in rabbits. Exp Eye Res 2000;71:23-31.
34. Zhu Z, Stevenson D, Schechter JE, Mircheff AK, Atkinson R, Trousdale MD. Lacrimal histopathology and ocular surface disease in a rabbit model of autoimmune dacryoadenitis. Cornea 2003;22:25-32.
35. Thomas PB, Zhu Z, Selvam S et al. Autoimmune dacryoadenitis and keratoconjunctivitis induced in rabbits by subcutaneous injection of autologous lymphocytes activated ex vivo against lacrimal antigens. J Autoimmun 2008;31:116-122.
36. Sheppard JD, Orenstein DM, Chao CC, Butala S, Kowalski RP. The ocular surface in cystic fibrosis. Ophthalmology 1989;96:1624-1630.
37. Morkeberg JC, Edmund C, Prause JU, Lanng S, Koch C, Michaelsen KF. Ocular findings in cystic fibrosis patients receiving vitamin A supplementation. Graefes Arch Clin Exp Ophthalmol 1995;233:709-713.
38. Ansari EA, Sahni K, Etherington C et al. Ocular signs and symptoms and vitamin A status in patients with cystic fibrosis treated with daily vitamin A supplements. Br J Ophthalmol 1999;83:688-691.
39. Mrugacz M. CCL4/MIP-1beta levels in tear fluid and serum of patients with cystic fibrosis. J Interferon Cytokine Res 2010;30:509-512.
40. Turner JT, Redman RS, Camden JM, Landon LA, Quissell DO. A rat parotid gland cell line, Par-C10, exhibits neurotransmitter-regulated transepithelial anion secretion. Am J Physiol 1998;275:C367-C374.
41. Dinudom A, Komwatana P, Young JA, Cook DI. A forskolinactivated Cl- current in mouse mandibular duct cells. Am J Physiol 1995;268:G806-G812.
42. Toth-Molnar E, Venglovecz V, Ozsvari B et al. New experimental method to study acid/base transporters and their regulation in lacrimal gland ductal epithelia. Invest Ophthalmol Vis Sci 2007;48:3746-3755.
43. Haarsma LD, Bardolph SL, Ubels JL. Recording of K+ currents from lacrimal gland duct cells. 2010; ARVO E-Abstract 4175.
44. Bradbury NA, Jilling T, Berta G, Sorscher EJ, Bridges RJ, Kirk KL. Regulation of plasma membrane recycling by CFTR. Science 1992;256:530-532.
45. Kuver R, Ramesh N, Lau S, Savard C, Lee SP, Osborne WR. Constitutive mucin secretion linked to CFTR expression. Biochem Biophys Res Commun 1994;203:1457-1462.
46. Ding C, Huang J, MacVeigh-Aloni M, Lu M. Not all lacrimal epithelial cells are created equal-heterogeneity of the rabbit lacrimal gland and differential secretion. Curr Eye Res 2011;11:971-978.
47. Millar TJ, Herok G, Koutavas H, Martin DK, Anderton PJ. Immunohistochemical and histochemical characterisation of epithelial cells of rabbit lacrimal glands in tissue sections and cell cultures. Tissue Cell 1996;28:301-312.