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Volumn 44, Issue 4, 2012, Pages 293-302

Laboratory identification of factor inhibitors: An update

Author keywords

APTT; Bethesda assay; Factor inhibitors; Lupus inhibitor; Mixing tests; Replacement therapy

Indexed keywords


EID: 84863645780     PISSN: 00313025     EISSN: 14653931     Source Type: Journal    
DOI: 10.1097/PAT.0b013e328353254d     Document Type: Article
Times cited : (51)

References (67)
  • 1
    • 76149093682 scopus 로고    scopus 로고
    • Laboratory identification of factor inhibitors: The perspective of a large tertiary hemophilia center
    • Kershaw G, Jayakodi D, Dunkley S. Laboratory identification of factor inhibitors: the perspective of a large tertiary hemophilia center. Semin Thromb Hemost 2009; 35: 760-8.
    • (2009) Semin Thromb Hemost , vol.35 , pp. 760-768
    • Kershaw, G.1    Jayakodi, D.2    Dunkley, S.3
  • 3
    • 33751040152 scopus 로고    scopus 로고
    • Inhibitor treatment in haemophilias A and B: Inhibitor diagnosis
    • DOI 10.1111/j.1365-2516.2006.01364.x
    • Dimichele D. Inhibitor treatment in haemophilias A and B: inhibitor diagnosis. Haemophilia 2006; 12 (Suppl 6): 37-42. (Pubitemid 44752488)
    • (2006) Haemophilia , vol.12 , Issue.SUPPL. 6 , pp. 37-42
    • Dimichele, D.M.1
  • 4
    • 28344447401 scopus 로고    scopus 로고
    • Cellular immune responses in hemophilia: Why do inhibitors develop in some, but not all hemophiliacs?
    • DOI 10.1111/j.1538-7836.2005.01375.x
    • White GC, Kempton CL, Grimsley A, Nielsen B, Roberts HR. Cellular immune responses in hemophilia: why do inhibitors develop in some, but not all hemophiliacs? J Thromb Haemost 2005; 3: 1676-81. (Pubitemid 41716553)
    • (2005) Journal of Thrombosis and Haemostasis , vol.3 , Issue.8 , pp. 1676-1681
    • White II, G.C.1    Kempton, C.L.2    Grimsley, A.3    Nielsen, B.4    Roberts, H.R.5
  • 5
    • 77449116760 scopus 로고    scopus 로고
    • The multifactorial etiology of inhibitor development in hemophilia: Genetics and environment
    • Gouw SC, van den Berg HM. The multifactorial etiology of inhibitor development in hemophilia: genetics and environment. Semin Thromb Hemost 2009; 35: 723-34.
    • (2009) Semin Thromb Hemost , vol.35 , pp. 723-734
    • Gouw, S.C.1    Van Den Berg, H.M.2
  • 6
    • 77449091890 scopus 로고    scopus 로고
    • Inhibitors in hemophilia A: Advances in elucidation of inhibitory mechanisms and in inhibitor management with bypassing agents
    • Ananyeva NM, Lee TK, Jain N, Shima M, Saenko EL. Inhibitors in hemophilia A: advances in elucidation of inhibitory mechanisms and in inhibitor management with bypassing agents. Semin Thromb Hemost 2009; 35: 735-51.
    • (2009) Semin Thromb Hemost , vol.35 , pp. 735-751
    • Ananyeva, N.M.1    Lee, T.K.2    Jain, N.3    Shima, M.4    Saenko, E.L.5
  • 7
    • 9144232123 scopus 로고    scopus 로고
    • Inhibitors in congenital coagulation disorders
    • DOI 10.1111/j.1365-2141.2004.05168.x
    • Key NS. Inhibitors in congenital coagulation disorders. Br J Haematol 2004; 127: 379-91. (Pubitemid 39539246)
    • (2004) British Journal of Haematology , vol.127 , Issue.4 , pp. 379-391
    • Key, N.S.1
  • 8
    • 23844533263 scopus 로고    scopus 로고
    • Comparative measurement of anti-factor VIII antibody by Bethesda assay and ELISA reveals restricted isotype profile and epitope specificity
    • DOI 10.1159/000086580
    • Towfighi F, Gharagozlou S, Sharifian RA, et al. Comparative measurement of anti-factor VIII antibody by Bethesda assay and ELISA reveals restricted isotype profile and epitope specificity. Acta Haematol 2005; 114: 84-90. (Pubitemid 41160935)
    • (2005) Acta Haematologica , vol.114 , Issue.2 , pp. 84-90
    • Towfighi, F.1    Gharagozlou, S.2    Sharifian, R.A.3    Kazemnejad, A.4    Esmailzadeh, K.5    Managhchi, M.R.6    Shokri, F.7
  • 9
    • 33750302875 scopus 로고    scopus 로고
    • Inhibitors to factor VIII-molecular basis
    • Lee C, Berntorp E, Hoots KW, editors Oxford: Blackwell Publishing
    • Oldenburg J, Tuddenham E. Inhibitors to factor VIII-molecular basis. In: Lee C, Berntorp E, Hoots KW, editors. Textbook of Hemophilia. Oxford: Blackwell Publishing, 2005; 59-63.
    • (2005) Textbook of Hemophilia , pp. 59-63
    • Oldenburg, J.1    Tuddenham, E.2
  • 10
    • 31444453462 scopus 로고    scopus 로고
    • Natural history of inhibitor development in children with severe hemophilia A treated with FVIII products
    • Lee C, Berntorp E, Hoots KW, editors Oxford: Blackwell Publishing
    • Lusher J. Natural history of inhibitor development in children with severe hemophilia A treated with FVIII products. In: Lee C, Berntorp E, Hoots KW, editors. Textbook of Hemophilia. Oxford: Blackwell Publishing, 2005; 34-8.
    • (2005) Textbook of Hemophilia , pp. 34-38
    • Lusher, J.1
  • 11
    • 34250708408 scopus 로고    scopus 로고
    • Treatment characteristics and the risk of inhibitor development: A multicenter cohort study among previously untreated patients with severe hemophilia A
    • DOI 10.1111/j.1538-7836.2007.02595.x
    • Gouw SC, Berg HMVD, Cessie SL, Bom JGVD. Treatment characteristics and the risk of inhibitor development: a multicenter cohort study among previously untreated patients with severe hemophilia A. J Thromb Haemost 2007; 5: 1383-90. (Pubitemid 46965364)
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , Issue.7 , pp. 1383-1390
    • Gouw, S.C.1    Van Den Berg, H.M.2    Le Cessie, S.3    Van Der Bom, J.G.4
  • 16
    • 0022480010 scopus 로고
    • Acquired inhibitors of plasma coagulation factors
    • Kasper CK, Ewing NP. Acquired inhibitors of plasma coagulation factors. J Med Technol 1986; 38: 431-9. (Pubitemid 16073720)
    • (1986) Journal of Medical Technology , vol.3 , Issue.8 , pp. 431-439
    • Kasper, C.K.1    Ewing, N.P.2
  • 17
    • 66349115640 scopus 로고    scopus 로고
    • Autoimmune hemophilia at rescue
    • Mannucci PM, Payvandi F. Autoimmune hemophilia at rescue. Haematologica 2009; 94: 459-61.
    • (2009) Haematologica , vol.94 , pp. 459-461
    • Mannucci, P.M.1    Payvandi, F.2
  • 18
    • 33847411624 scopus 로고    scopus 로고
    • Acquired hemophilia A in the United Kingdom: A 2-year national surveillance study by the United Kingdom Haemophilia Centre Doctors' organisation
    • DOI 10.1182/blood-2006-06-029850
    • Collins PW, Hirsch S, Baglin TP, et al. UK Haemophilia Centre Doctors' Organisation Acquired hemophilia A in the United Kingdom: a 2-year national surveillance study by the United Kingdom Haemophilia Centre Doctors' Organisation. Blood 2007; 109: 1870-7. (Pubitemid 46348182)
    • (2007) Blood , vol.109 , Issue.5 , pp. 1870-1877
    • Collins, P.W.1    Hirsch, S.2    Baglin, T.P.3    Dolan, G.4    Hanley, J.5    Makris, M.6    Keeling, D.M.7    Liesner, R.8    Brown, S.A.9    Hay, C.R.M.10
  • 19
    • 77449132898 scopus 로고    scopus 로고
    • Twelve years of experience of acquired hemophilia A: Trials and tribulations in south Australia
    • Tay L, Duncan E, Singhal D, et al. Twelve years of experience of acquired hemophilia A: trials and tribulations in south Australia. Semin Thromb Hemost 2009; 35: 769-77.
    • (2009) Semin Thromb Hemost , vol.35 , pp. 769-777
    • Tay, L.1    Duncan, E.2    Singhal, D.3
  • 20
    • 0019501541 scopus 로고
    • A survey of 215 non-hemophilic patients with inhibitors to factor VIII
    • Green D, Lechner K. A survey of 215 non-hemophiliac patients with inhibitors to factor VIII. Thromb Haemost 1981; 45: 200-3. (Pubitemid 11081028)
    • (1981) Thrombosis and Haemostasis , vol.45 , Issue.3 , pp. 200-203
    • Green, D.1    Lechner, K.2
  • 21
    • 31444452280 scopus 로고    scopus 로고
    • Inhibitors in hemophilia B
    • Lee C, Berntorp E, Hoots KW, editors Oxford: Blackwell Publishing
    • Warrier I. Inhibitors in hemophilia B. In: Lee C, Berntorp E, Hoots KW, editors. Textbook of Hemophilia. Oxford: Blackwell Publishing, 2005.
    • (2005) Textbook of Hemophilia
    • Warrier, I.1
  • 22
    • 0035022048 scopus 로고    scopus 로고
    • Haemophilia B mutations in Sweden: A population-based study of mutational heterogeneity
    • DOI 10.1046/j.1365-2141.2001.02759.x
    • Llung R, Petrini P, Tengborn L, Sjorin E. Haemophilia B mutations in Sweden: a population-based study of mutational heterogeneity. Br J Haemat 2001; 113: 81-6. (Pubitemid 32423306)
    • (2001) British Journal of Haematology , vol.113 , Issue.1 , pp. 81-86
    • Ljung, R.1    Petrini, P.2    Tengborn, L.3    Sjorin, E.4
  • 23
    • 34447123490 scopus 로고    scopus 로고
    • Treatment of inhibitors in hemophilia B
    • Lee C, Berntorp E, Hoots KW, editors Oxford: Blackwell Publishing
    • Brown SA. Treatment of inhibitors in hemophilia B. In: Lee C, Berntorp E, Hoots KW, editors. Textbook of Hemophilia. Oxford: Blackwell Publishing, 2005; 101-5.
    • (2005) Textbook of Hemophilia , pp. 101-105
    • Brown, S.A.1
  • 25
    • 66149179129 scopus 로고    scopus 로고
    • Acquired factor Vinhibitor. A problem based systematic review
    • Ang AL, Kuperan P, Ng CH, Ng HJ. Acquired factor Vinhibitor. A problem based systematic review. Thromb Haemost 2009; 101: 852-9.
    • (2009) Thromb Haemost , vol.101 , pp. 852-859
    • Ang, A.L.1    Kuperan, P.2    Ng, C.H.3    Ng, H.J.4
  • 28
    • 77954876755 scopus 로고    scopus 로고
    • Topical recombinant human thrombin in surgical hemostasis
    • Bowman LJ, Anderson CD, Chapman WC. Topical recombinant human thrombin in surgical hemostasis. Semin Thromb Hemost 2010; 36: 477-84.
    • (2010) Semin Thromb Hemost , vol.36 , pp. 477-484
    • Bowman, L.J.1    Anderson, C.D.2    Chapman, W.C.3
  • 35
    • 85171928518 scopus 로고    scopus 로고
    • Acquired von Willebrand Disease: Potential contribution of the VWF: CB to the identification of functionally inhibiting auto-antibodies to von Willebrand factor
    • Coleman R, Favaloro EJ, Soltani S, Keng TB. Acquired von Willebrand Disease: Potential contribution of the VWF: CB to the identification of functionally inhibiting auto-antibodies to von Willebrand factor. J Thromb Haemost 2008; 4: 1051-2.
    • (2008) J Thromb Haemost , vol.4 , pp. 1051-1052
    • Coleman, R.1    Favaloro, E.J.2    Soltani, S.3    Keng, T.B.4
  • 36
    • 52449098463 scopus 로고    scopus 로고
    • Clinical and molecular markers of inherited von Willebrand disease type 3: Are deletions of the VWF gene associated with alloantibodies to VWF?
    • Federici AB. Clinical and molecular markers of inherited von Willebrand disease type 3: are deletions of the VWF gene associated with alloantibodies to VWF? J Thromb Haemost 2008; 6: 1726-8.
    • (2008) J Thromb Haemost , vol.6 , pp. 1726-1728
    • Federici, A.B.1
  • 37
  • 38
    • 77953862089 scopus 로고    scopus 로고
    • Laboratory testing in disseminated intravascular coagulation
    • Favaloro EJ. Laboratory testing in disseminated intravascular coagulation. Semin Thromb Hemost 2010; 36: 458-67.
    • (2010) Semin Thromb Hemost , vol.36 , pp. 458-467
    • Favaloro, E.J.1
  • 39
    • 53049091449 scopus 로고    scopus 로고
    • Laboratory testing for lupus anticoagulants: Diagnostic criteria and use of screening, mixing, and confirmatory studies
    • Tripodi A. Laboratory testing for lupus anticoagulants: diagnostic criteria and use of screening, mixing, and confirmatory studies. Semin Thromb Hemost 2008; 34: 373-8.
    • (2008) Semin Thromb Hemost , vol.34 , pp. 373-378
    • Tripodi, A.1
  • 40
    • 34247860294 scopus 로고    scopus 로고
    • Acquired inhibitors to factor VIII
    • Lee C, Berntorp E, Hoots KW, editors Oxford: Blackwell Publishing
    • Kessler C, Asatiani E. Acquired inhibitors to factor VIII. In: Lee C, Berntorp E, Hoots KW, editors. Textbook of Hemophilia. Oxford: Blackwell Publishing, 2005; 86-90.
    • (2005) Textbook of Hemophilia , pp. 86-90
    • Kessler, C.1    Asatiani, E.2
  • 41
    • 0017387653 scopus 로고
    • Detection of factor VIII inhibitors with the partial thromboplastin time
    • Lossing T, Kasper C, Feinstein D. Detection of factor VIII inhibitors with the partial thromboplastin time. Blood 1977; 49: 793-7. (Pubitemid 8093475)
    • (1977) Blood , vol.49 , Issue.5 , pp. 793-797
    • Lossing, T.S.1    Kasper, C.K.2    Feinstein, D.I.3
  • 43
    • 78650012663 scopus 로고    scopus 로고
    • Laboratory investigation of lupus anticoagulants: Mixing studies are sometimes required
    • Favaloro EJ, Bonar R, Zebeljan D, Kershaw G, Marsden K. Laboratory investigation of lupus anticoagulants: mixing studies are sometimes required. J Thromb Haemost 2010; 8: 2828-31.
    • (2010) J Thromb Haemost , vol.8 , pp. 2828-2831
    • Favaloro, E.J.1    Bonar, R.2    Zebeljan, D.3    Kershaw, G.4    Marsden, K.5
  • 44
    • 84861342503 scopus 로고    scopus 로고
    • Evaluating laboratory approaches to the identification of lupus anticoagulants: A diagnostic challenge from the RCPA Haematology QAP
    • Bonar R, Favaloro EJ, Zebeljan D, et al. Evaluating laboratory approaches to the identification of lupus anticoagulants: A diagnostic challenge from the RCPA Haematology QAP. Pathology 2012; 44: 240-7.
    • (2012) Pathology , vol.44 , pp. 240-247
    • Bonar, R.1    Favaloro, E.J.2    Zebeljan, D.3
  • 45
    • 77449096331 scopus 로고    scopus 로고
    • The between-laboratory variation of factor VIII inhibitor testing: The experience of the external quality assessment program of the ECAT foundation
    • Meijer P, Verbruggen B. The between-laboratory variation of factor VIII inhibitor testing: the experience of the external quality assessment program of the ECAT foundation. Semin Thromb Hemost 2009; 35: 786-93.
    • (2009) Semin Thromb Hemost , vol.35 , pp. 786-793
    • Meijer, P.1    Verbruggen, B.2
  • 47
  • 49
    • 0036332155 scopus 로고    scopus 로고
    • A 4% solution of bovine serum albumin may be used in place of factor VII:C deficient plasma in the control sample in the Nijmegen modification of the Bethesda factor VIII:C inhibitor assay
    • Verbruggen B, van Heerde W, Novákovà I, Lillicrap D, Giles A. A 4% solution of bovine serum albumin may be used in place of factor VIII: C deficient plasma in the control sample in the Nijmegen Modification of the Bethesda factor VIII: C inhibitor assay. Thromb Haemost 2002; 88: 362-4. (Pubitemid 34873724)
    • (2002) Thrombosis and Haemostasis , vol.88 , Issue.2 , pp. 362-364
    • Verbruggen, B.1    Van Heerde, W.2    Novakova, I.3    Lillicrap, D.4    Giles, A.5
  • 51
    • 0024271310 scopus 로고    scopus 로고
    • Modification of the Bethesda assay for factor FVIII or IX inhibitors to improve efficiency
    • Gadarowski JJ, Czapek EE, Ontiveros JD, Pedraza JL. Modification of the Bethesda assay for factor FVIII or IX inhibitors to improve efficiency. Acta Haematol 1998; 80: 134-8.
    • (1998) Acta Haematol , vol.80 , pp. 134-138
    • Gadarowski, J.J.1    Czapek, E.E.2    Ontiveros, J.D.3    Pedraza, J.L.4
  • 52
    • 0038441397 scopus 로고    scopus 로고
    • A new ELISA assay for diagnosis of acquired von Willebrand syndrome
    • Siaka C, Rugeri L, Caron C, Goudemand J. A new ELISA assay for diagnosis of acquired von Willebrand Syndrome. Haemophilia 2003; 9: 303-8. (Pubitemid 36622033)
    • (2003) Haemophilia , vol.9 , Issue.3 , pp. 303-308
    • Siaka, C.1    Rugeri, L.2    Caron, C.3    Goudemand, J.4
  • 53
    • 43749102064 scopus 로고    scopus 로고
    • Acquired von Willebrand disease: Potential contribution of the von Willebrand factor collagen-binding to the identification of functionally inhibiting auto-antibodies to von Willebrand factor: A rebuttal
    • DOI 10.1111/j.1538-7836.2008.02967.x
    • Guerin V, Ryman A, Velez F. Acquired von Willebrand disease: potential contribution of the von Willebrand factor collagen-binding to the identification of functionally inhibiting auto-antibodies to von Willebrand factor: a rebuttal. J Thromb Haemost 2008; 6: 1051-2. (Pubitemid 351689936)
    • (2008) Journal of Thrombosis and Haemostasis , vol.6 , Issue.6 , pp. 1051-1052
    • Guerin, V.1    Ryman, A.2    Velez, F.3
  • 55
    • 34648816828 scopus 로고    scopus 로고
    • Mis-identification of factor inhibitors by diagnostic haemostasis laboratories: Recognition of pitfalls and elucidation of strategies. A follow up to a large multicentre evaluation
    • DOI 10.1080/00313020701569998, PII 782040329
    • Favaloro EJ, Bonar R, Duncan E, et al. (on behalf of the RCPA QAP in Haematology Haemostasis Committee). Mis-identification of factor inhibitors by diagnostic haemostasis laboratories: recognition of pitfalls and elucidation of strategies. A follow up to a large multicentre evaluation. Pathology 2007; 39: 504-11. (Pubitemid 47454494)
    • (2007) Pathology , vol.39 , Issue.5 , pp. 504-511
    • Favaloro, E.J.1    Bonar, R.2    Duncan, E.3    Earl, G.4    Low, J.5    Aboud, M.6    Just, S.7    Sioufi, J.8    Street, A.9    Marsden, K.10
  • 56
    • 77449099048 scopus 로고    scopus 로고
    • Investigations from external quality assurance programs reveal a high degree of variation in the laboratory identification of coagulation factor inhibitors
    • (on behalf RCPA Haematology QAP Haemostasis Committee)
    • Favaloro EJ, Bonar R, Kershaw G, Duncan E, Sioufi J, Marsden K (on behalf RCPA Haematology QAP Haemostasis Committee). Investigations from external quality assurance programs reveal a high degree of variation in the laboratory identification of coagulation factor inhibitors. Semin Thromb Hemost 2009; 35: 794-805.
    • (2009) Semin Thromb Hemost , vol.35 , pp. 794-805
    • Favaloro, E.J.1    Bonar, R.2    Kershaw, G.3    Duncan, E.4    Sioufi, J.5    Marsden, K.6
  • 57
    • 77449093450 scopus 로고    scopus 로고
    • Laboratory identification of factor VIII inhibitors in the real world: The experience from Australasia
    • (on behalf RCPA Haematology QAP Haemostasis Committee)
    • Favaloro EJ, Bonar R, Kershaw G, Mohammed S, Duncan E, Marsden K (on behalf RCPA Haematology QAP Haemostasis Committee). Laboratory identification of factor VIII inhibitors in the real world: the experience from Australasia. Haemophilia 2010; 16: 662-70.
    • (2010) Haemophilia , vol.16 , pp. 662-670
    • Favaloro, E.J.1    Bonar, R.2    Kershaw, G.3    Mohammed, S.4    Duncan, E.5    Marsden, K.6
  • 58
    • 77449158822 scopus 로고    scopus 로고
    • Interlaboratory variation in factor VIII: C inhibitor assay results is sufficient to influence patient management: Data from the UK national quality external assessment scheme for blood coagulation
    • Kitchen S, Jennings I, Preston FE, Kitchen DP, Woods TA, Walker ID. Interlaboratory variation in factor VIII: C inhibitor assay results is sufficient to influence patient management: data from the UK national quality external assessment scheme for blood coagulation. Semin Thromb Hemost 2009; 35: 778-85.
    • (2009) Semin Thromb Hemost , vol.35 , pp. 778-785
    • Kitchen, S.1    Jennings, I.2    Preston, F.E.3    Kitchen, D.P.4    Woods, T.A.5    Walker, I.D.6
  • 59
    • 65349196134 scopus 로고    scopus 로고
    • Laboratory assessment of factor VIII inhibitor titer: The North American Specialized Coagulation Laboratory Association experience
    • NASCOLA Proficiency Testing Committee
    • Peerschke EI, Castellone DD, Ledford-Kraemer M, Van Cott EM, Meijer P; NASCOLA Proficiency Testing Committee. Laboratory assessment of factor VIII inhibitor titer: the North American Specialized Coagulation Laboratory Association experience. Am J Clin Pathol 2009; 131: 552-8.
    • (2009) Am J Clin Pathol , vol.131 , pp. 552-558
    • Peerschke, E.I.1    Castellone, D.D.2    Ledford-Kraemer, M.3    Van Cott, E.M.4    Meijer, P.5
  • 60
    • 0038383605 scopus 로고    scopus 로고
    • The epidemiology of inhibitors in haemophilia A: A systematic review
    • Wight J, Paisley S. The epidemiology of inhibitors in haemophilia A: a systematic review. Haemophilia 2003; 9: 418-35. (Pubitemid 36874391)
    • (2003) Haemophilia , vol.9 , Issue.4 , pp. 418-435
    • Wight, J.1    Paisley, S.2
  • 61
    • 77954506432 scopus 로고    scopus 로고
    • Rate of inhibitor development in previously untreated hemophilia A patients treated with plasma-derived or recombinant factor VIII concentrates: A systematic review
    • Iorio A, Halimeh S, Holzhauer S, et al. Rate of inhibitor development in previously untreated hemophilia A patients treated with plasma-derived or recombinant factor VIII concentrates: a systematic review. J Thromb Haemost 2010; 8: 1256-65.
    • (2010) J Thromb Haemost , vol.8 , pp. 1256-1265
    • Iorio, A.1    Halimeh, S.2    Holzhauer, S.3
  • 62
    • 78149492011 scopus 로고    scopus 로고
    • Von Willebrand factor-containing factor VIII concentrates and inhibitors in haemophilia A. A critical literature review
    • Franchini M, Lippi G. Von Willebrand factor-containing factor VIII concentrates and inhibitors in haemophilia A. A critical literature review. Thromb Haemost 2010; 104: 931-40.
    • (2010) Thromb Haemost , vol.104 , pp. 931-940
    • Franchini, M.1    Lippi, G.2
  • 63
    • 84855912746 scopus 로고    scopus 로고
    • Cumulative inhibitor incidence in previously untreated patients with severe hemophilia A treated with plasma-derived versus recombinant factor VIII concentrates: A critical systematic review
    • Franchini M, Tagliaferri A, Mengoli C, Cruciani M. Cumulative inhibitor incidence in previously untreated patients with severe hemophilia A treated with plasma-derived versus recombinant factor VIII concentrates: A critical systematic review. Crit Rev Oncol Hematol 2012; 81: 82-93.
    • (2012) Crit Rev Oncol Hematol , vol.81 , pp. 82-93
    • Franchini, M.1    Tagliaferri, A.2    Mengoli, C.3    Cruciani, M.4
  • 64
    • 78049285843 scopus 로고    scopus 로고
    • Plasma-derived versus recombinant factor VIII concentrates for the treatment of haemophilia A: Plasma-derived is better
    • Mannucci PM. Plasma-derived versus recombinant factor VIII concentrates for the treatment of haemophilia A: plasma-derived is better. Blood Transfus 2010; 8: 288-91.
    • (2010) Blood Transfus , vol.8 , pp. 288-291
    • Mannucci, P.M.1
  • 65
    • 78049271862 scopus 로고    scopus 로고
    • Plasma-derived versus recombinant Factor VIII concentrates for the treatment of haemophilia A: Recombinant is better
    • Franchini M. Plasma-derived versus recombinant Factor VIII concentrates for the treatment of haemophilia A: recombinant is better. Blood Transfus 2010; 8: 292-6.
    • (2010) Blood Transfus , vol.8 , pp. 292-296
    • Franchini, M.1
  • 66
    • 79959529406 scopus 로고    scopus 로고
    • Recombinant factor concentrates may increase inhibitor development: A single centre cohort study
    • Strauss T, Lubetsky A, Ravid B, et al. Recombinant factor concentrates may increase inhibitor development: a single centre cohort study. Haemophilia 2011; 17: 625-9.
    • (2011) Haemophilia , vol.17 , pp. 625-629
    • Strauss, T.1    Lubetsky, A.2    Ravid, B.3
  • 67
    • 80055114308 scopus 로고    scopus 로고
    • Can B-domain deletion alter the immunogenicity of recombinant factor VIII? A meta-analysis of prospective clinical studies
    • Aledort LM, Navickis RJ, Wilkes MM. Can B-domain deletion alter the immunogenicity of recombinant factor VIII? A meta-analysis of prospective clinical studies. J Thromb Haemost 2011; 9: 2180-92.
    • (2011) J Thromb Haemost , vol.9 , pp. 2180-2192
    • Aledort, L.M.1    Navickis, R.J.2    Wilkes, M.M.3


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