Laboratory investigation of lupus anticoagulants: Mixing studies are sometimes required

Journal of Thrombosis and Haemostasis

Volumn 8, Issue 12, 2010, Pages 2828-2831

  Favaloro, E J ^a   Bonar, R ^b   Zebeljan, D ^c   Kershaw, G ^d   Marsden, K ^b  

^a WESTMEAD HOSPITAL   (Australia)

^b Royal College of Pathologists of Australasia RCPA   (Australia)

^c LIVERPOOL HOSPITAL   (Australia)

^d ROYAL PRINCE ALFRED HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BETA2 GLYCOPROTEIN 1 ANTIBODY; CARDIOLIPIN ANTIBODY; LUPUS ANTICOAGULANT; PARAPROTEIN; PHOSPHOLIPID; PHOSPHOLIPID ANTIBODY;

BLOOD CLOTTING TEST; HUMAN; LABORATORY TEST; LETTER; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTHROMBIN TIME; QUALITY CONTROL;

HUMANS; LABORATORY TECHNIQUES AND PROCEDURES; LUPUS COAGULATION INHIBITOR; LUPUS ERYTHEMATOSUS, SYSTEMIC; QUALITY ASSURANCE, HEALTH CARE;

EID: 78650012663     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2010.04090.x     Document Type: Letter

References (7)

1. Pengo V, Tripodi A, Reber G, Rand JH, Ortel TL, Galli M, De Groot PG. Update of the guidelines for lupus anticoagulant detection. J Thromb Haemost 2009; 7: 1737-40.
2. Brandt JT, Triplett DA, Alving B, Scharrer I. Criteria for the diagnosis of lupus anticoagulants: an update On behalf of the Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibody of the Scientific and Standardisation Committee of the ISTH. Thromb Haemost 1995; 74: 1185-90.
3. Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, Derksen RHWM, De Groot PG, Koike T, Meroni PL, Reber G, Shoenfeld Y, Tincani A, Vlachoyiannopoulos PG, Krilis SA. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 2006; 4: 295-306.
4. Aboud M, Roddie C, Ward C, Coyle L. To mix with pooled normal plasma or not to mix: a comparative study of two approaches to assess lupus anticoagulant inhibitory activity in the dilute Russell Viper venom method. Clin Chem 2007; 53: 143-5.
5. Thom J, Ivey L, Eikelboom J. Normal plasma mixing studies in the laboratory diagnosis of lupus anticoagulant. J Thromb Haemost 2003; 1: 2689-91.
6. Devreese KMJ. No more mixing tests required for integrated assay systems in the laboratory diagnosis of lupus anticoagulants? J Thromb Haemost 2010; 8: 1120-2.
7. Details of the Royal College of Pathologists of Australasia (RCPA) Haematology Quality Assurance Program (QAP) and test modules. Accessed 19 August 2010.