Pdl1 is a putative lipase that enhances Photorhabdus toxin complex secretion

PLoS Pathogens

Volumn 8, Issue 5, 2012, Pages

  Yang, Guowei ^a   Hernández Rodríguez, Carmen Sara ^b   Beeton, Michael L ^b   Wilkinson, Paul ^c   ffrench Constant, Richard H ^d   Waterfield, Nicholas R ^b  

^a INSTITUTE OF PATHOGEN BIOLOGY   (China)

^b University of Bath   (United Kingdom)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

^d UNIVERSITY OF EXETER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; BACTERIAL PROTEIN; BACTERIAL TOXIN; ORF53 PROTEIN; PDL1 PROTEIN; REGULATOR PROTEIN; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; VIRULENCE FACTOR; MEMBRANE PROTEIN; TOXIN A, PHOTORHABDUS; TOXIN B, PHOTORHABDUS;

ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; COMPARATIVE GENOMIC HYBRIDIZATION; COMPLEX FORMATION; CONTROLLED STUDY; ESCHERICHIA COLI; GENE EXPRESSION SYSTEM; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERON; PHOTORHABDUS LUMINESCENS; PROTEIN SECRETION; SUPERNATANT; TYPE IV SECRETION SYSTEM; ANIMAL; BACTERIAL SECRETION SYSTEM; GENETICS; LARVA; MANDUCA; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PHOTORHABDUS; PHYSIOLOGY; SECRETION (PROCESS); XENORHABDUS;

ESCHERICHIA COLI; HEXAPODA; NEGIBACTERIA; PHOTORHABDUS; PHOTORHABDUS LUMINESCENS; XENORHABDUS;

ANIMALS; BACTERIAL PROTEINS; BACTERIAL SECRETION SYSTEMS; BACTERIAL TOXINS; ESCHERICHIA COLI; LARVA; LIPASE; MANDUCA; MEMBRANE PROTEINS; PHOTORHABDUS; XENORHABDUS;

EID: 84863639129     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002692     Document Type: Article

References (39)

1. Waterfield NR, Ciche T, Clarke D, (2009) Photorhabdus and a host of hosts. Annu Rev Microbiol 63: 557-574.
2. Waterfield NR, Bowen DJ, Fetherston JD, Perry RD, ffrench-Constant RH, (2001) The tc genes of Photorhabdus: a growing family. Trends Microbiol 9: 185-191.
3. Waterfield N, Hares M, Yang G, Dowling A, ffrench-Constant R, (2005) Potentiation and cellular phenotypes of the insecticidal Toxin complexes of Photorhabdus bacteria. Cell Microbiol 7: 373-382.
4. Bowen D, Rocheleau TA, Blackburn M, Andreev O, Golubeva E, et al. (1998) Insecticidal toxins from the bacterium Photorhabdus luminescens. Science 280: 2129-2132.
5. Blackburn M, Golubeva E, Bowen D, ffrench-Constant RH, (1998) A novel insecticidal toxin from Photorhabdus luminescens: histopathological effects of Toxin complex A (Tca) on the midgut of Manduca sexta. Appl Environ Microbiol 64: 3036-3041.
6. ffrench-Constant R, Waterfield N, (2006) An ABC guide to the bacterial toxin complexes. Adv Appl Microbiol 58: 169-183.
7. Lee SC, Stoilova-McPhie S, Baxter L, Fulop V, Henderson J, et al. (2007) Structural characterisation of the insecticidal toxin XptA1, reveals a 1.15 MDa tetramer with a cage-like structure. J Mol Biol 366: 1558-1568.
8. Sheets JJ, Hey TD, Fencil KJ, Burton SL, Ni W, et al. (2011) Insecticidal Toxin Complex Proteins from Xenorhabdus nematophilus: STRUCTURE AND PORE FORMATION. J Biol Chem 286: 22742-22749.
9. Lang AE, Schmidt G, Schlosser A, Hey TD, Larrinua IM, et al. (2010) Photorhabdus luminescens toxins ADP-ribosylate actin and RhoA to force actin clustering. Science 327: 1139-1142.
10. Hares MC, Hinchliffe SJ, Strong PC, Eleftherianos I, Dowling AJ, et al. (2008) The Yersinia pseudotuberculosis and Yersinia pestis toxin complex is active against cultured mammalian cells. Microbiology 154: 3503-3517.
11. Tennant SM, Skinner NA, Joe A, Robins-Browne RM, (2005) Homologues of insecticidal toxin complex genes in Yersinia enterocolitica biotype 1A and their contribution to virulence. Infect Immun 73: 6860-6867.
12. Sergeant M, Jarrett P, Ousley M, Morgan JA, (2003) Interactions of insecticidal toxin gene products from Xenorhabdus nematophilus PMFI296. Appl Environ Microbiol 69: 3344-3349.
13. Waterfield N, Dowling A, Sharma S, Daborn PJ, Potter U, et al. (2001) Oral toxicity of Photorhabdus luminescens W14 toxin complexes in Escherichia coli. Appl Environ Microbiol 67: 5017-5024.
14. Liu D, Burton S, Glancy T, Li ZS, Hampton R, et al. (2003) Insect resistance conferred by 283-kDa Photorhabdus luminescens protein TcdA in Arabidopsis thaliana. Nat Biotechnol 21: 1307-1313.
15. Erickson DL, Waterfield NR, Vadyvaloo V, Long D, Fischer ER, et al. (2007) Acute oral toxicity of Yersinia pseudotuberculosis to fleas: implications for the evolution of vector-borne transmission of plague. Cell Microbiol 9: 2658-2666.
16. Zhao R, Han R, Qiu X, Yan X, Cao L, et al. (2008) Cloning and heterologous expression of insecticidal-protein-encoding genes from Photorhabdus luminescens TT01 in Enterobacter cloacae for termite control. Appl Environ Microbiol 74: 7219-7226.
17. Bowen DJ, (1995) Characterization of a high molecular weight insecticidal protein complex produced by the entomothogenic bacterium Photorhabdus luminescens [PhD] Madison (Wisconsin) University of Wisconsin-Madison.
18. Waterfield NR, Daborn PJ, ffrench-Constant RH, (2002) Genomic islands in Photorhabdus. Trends Microbiol 10: 541-545.
19. Silva CP, Waterfield NR, Daborn PJ, Dean P, Chilver T, et al. (2002) Bacterial infection of a model insect: Photorhabdus luminescens and Manduca sexta. Cell Microbiol 6: 329-339.
20. Waterfield NR, Daborn PJ, ffrench-Constant RH, (2004) Insect pathogenicity islands in the insect pathogenic bacterium Photorhabdus. Physiol Entomol 29: 1-11.
21. Waterfield N, Kamita SG, Hammock BD, ffrench-Constant R, (2005) The Photorhabdus Pir toxins are similar to a developmentally regulated insect protein but show no juvenile hormone esterase activity. FEMS Microbiol Lett 245: 47-52.
22. Daborn PJ, Waterfield N, Silva CP, Au CPY, Sharma S, et al. (2002) A single Photorhabdus gene makes caterpillars floppy (mcf) allows Esherichia coli to persist within and kill insects. Proc Natl Acad Sci U S A 99: 10742-10747.
23. Rowe GE, Welch RA, (1994) Assays of hemolytic toxins. Methods Enzymol 235: 657-667.
24. Gerrard JG, Joyce SA, Clarke DJ, ffrench-Constant RH, Nimmo GR, et al. (2006) Nematode symbiont for Photorhabdus asymbiotica. Emerg Infect Dis 12: 1562-1564.
25. Peat SM, Ffrench-Constant RH, Waterfield NR, Marokhazi J, Fodor A, et al. (2010) A robust phylogenetic framework for the bacterial genus Photorhabdus and its use in studying the evolution and maintenance of bioluminescence: a case for 16S, gyrB, and glnA. Mol Phylogenet Evol 57: 728-740.
26. Marokhazi J, Waterfield N, LeGoff G, Feil E, Stabler R, et al. (2003) Using a DNA microarray to investigate the distribution of insect virulence factors in strains of photorhabdus bacteria. J Bacteriol 185: 4648-4656.
27. Duchaud E, Rusniok C, Frangeul L, Buchrieser C, Givaudan A, et al. (2003) The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens. Nat Biotechnol 21: 1307-1313.
28. Daborn PJ, Waterfield N, Blight MA, Ffrench-Constant RH, (2001) Measuring virulence factor expression by the pathogenic bacterium Photorhabdus luminescens in culture and during insect infection. J Bacteriol 183: 5834-5839.
29. del Castillo FJ, Leal SC, Moreno F, del Castillo I, (1997) The Escherichia coli K-12 sheA gene encodes a 34-kDa secreted haemolysin. Mol Microbiol 25: 107-115.
30. Hill CW, Sandt CH, Vlazny DA, (1994) Rhs elements of Escherichia coli: a family of genetic composites each encoding a large mosaic protein. Mol Microbiol 12: 865-871.
31. Thompson BJ, Widdick DA, Hicks MG, Chandra G, Sutcliffe IC, et al. (2010) Investigating lipoprotein biogenesis and function in the model Gram-positive bacterium Streptomyces coelicolor. Mol Microbiol E-pub ahead of print.
32. Hutchings MI, Palmer T, Harrington DJ, Sutcliffe IC, (2009) Lipoprotein biogenesis in Gram-positive bacteria: knowing when to hold 'em, knowing when to fold 'em. Trends Microbiol 17: 13-21.
33. Cowles CE, Goodrich-Blair H, (2004) Characterization of a lipoprotein, NilC, required by Xenorhabdus nematophila for mutualism with its nematode host. Mol Microbiol 54: 464-477.
34. Zhao S, Sandt CH, Feulner G, Vlazny DA, Gray JA, et al. (1993) Rhs elements of Escherichia coli K-12: complex composites of shared and unique components that have different evolutionary histories. J Bacteriol 175: 2799-2808.
35. McNulty C, Thompson J, Barrett B, Lord L, Andersen C, et al. (2006) The cell surface expression of group 2 capsular polysaccharides in Escherichia coli: the role of KpsD, RhsA and a multi-protein complex at the pole of the cell. Mol Microbiol 59: 907-922.
36. Pukatzki S, Ma AT, Revel AT, Sturtevant D, Mekalanos JJ, (2007) Type VI secretion system translocates a phage tail spike-like protein into target cells where it cross-links actin. Proc Natl Acad Sci U S A 104: 15508-15513.
37. Waterfield NR, Sanchez-Contreras M, Eleftherianos I, Dowling A, Wilkinson P, et al. (2008) Rapid Virulence Annotation (RVA): identification of virulence factors using a bacterial genome library and multiple invertebrate hosts. Proc Natl Acad Sci U S A 105: 15967-15972.
38. Pukatzki S, Ma AT, Sturtevant D, Krastins B, Sarracino D, et al. (2006) Identification of a conserved bacterial protein secretion system in Vibrio cholerae using the Dictyostelium host model system. Proc Natl Acad Sci U S A 103: 1528-1533.
39. Mougous JD, Cuff ME, Raunser S, Shen A, Zhou M, et al. (2006) A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus. Science 312: 1526-1530.