Enantioselective synthesis of a dual orexin receptor antagonist

Organic Letters

Volumn 14, Issue 13, 2012, Pages 3458-3461

  Mangion, Ian K ^a   Sherry, Benjamin D ^a   Yin, Jingjun ^a   Fleitz, Fred J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(4 (5 CHLORO 1,3 BENZOXAZOL 2 YL) 7 METHYL 1,4 DIAZEPAN 1 YL)(5 METHYL 2 (2H 1,2,3 TRIAZOL 2 YL)PHENYL)METHANONE; (4-(5-CHLORO-1,3-BENZOXAZOL-2-YL)-7-METHYL-1,4-DIAZEPAN-1-YL)(5-METHYL-2-(2H-1,2,3-TRIAZOL-2-YL)PHENYL)METHANONE; AZEPINE DERIVATIVE; G PROTEIN COUPLED RECEPTOR; NEUROPEPTIDE RECEPTOR; OREXIN RECEPTORS; TRIAZOLE DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AZEPINES; MOLECULAR STRUCTURE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 84863633075     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol3014123     Document Type: Article

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