Sequestration of Sup35 by aggregates of huntingtin fragments causes toxicity of [PSI+] yeast

Journal of Biological Chemistry

Volumn 287, Issue 28, 2012, Pages 23346-23355

  Zhao, Xiaohong ^a   Park, Yang Nim ^a   Todor, Horia ^a   Moomau, Christine ^a   Masison, Daniel ^b   Eisenberg, Evan ^a   Greene, Lois E ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C-TERMINAL DOMAINS; HUNTINGTIN; N-TERMINALS; POLYPROLINE;

AGGREGATES; AMINO ACIDS; GLYCOPROTEINS; TOXICITY;

YEAST;

CELL PROTEIN; HUNTINGTIN; POLYGLUTAMINE; PRION PROTEIN; PROTEIN SUP35; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; YEAST;

BLOTTING, WESTERN; GLUTAMINE; HUMANS; MICROSCOPY, CONFOCAL; MUTATION; NERVE TISSUE PROTEINS; PEPTIDE FRAGMENTS; PEPTIDE TERMINATION FACTORS; PLASMIDS; PRIONS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSFORMATION, GENETIC; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 84863624498     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.287748     Document Type: Article

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