Identification and validation of inhibitor-responsive kinase substrates using a new paradigm to measure kinase-specific protein phosphorylation index

Journal of Proteome Research

Volumn 11, Issue 7, 2012, Pages 3637-3649

  Li, Xiang ^a   Rao, Varsha ^a   Jin, Jin ^a   Guan, Bin ^a   Anderes, Kenna L ^b   Bieberich, Charles J ^a,c  

^a UNIVERSITY OF MARYLAND BALTIMORE COUNTY   (United States)

^b ApoCell Inc   (United States)

^c UNIVERSITY OF MARYLAND   (United States)

Author keywords

biomarker; CK2; kinase inhibitor; pharmacodynamics; phosphorylation index

Indexed keywords

CASEIN KINASE II; CX 4945; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; DRUG EFFICACY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOUSE; NONHUMAN; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

ANIMALS; CASEIN KINASE II; CHROMATOGRAPHY, AFFINITY; FEMALE; HELA CELLS; HUMANS; LEUKOCYTES, MONONUCLEAR; MICE; MOLECULAR CHAPERONES; NAPHTHYRIDINES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOME;

EID: 84863615214     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr3000514     Document Type: Article

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