Prediction of neuroprotective treatment efficiency using a HRMAS NMR-based statistical model of refractory status epilepticus on mouse: A metabolomic approach supported by histology

Journal of Proteome Research

Volumn 11, Issue 7, 2012, Pages 3782-3795

  Fauvelle, Florence ^a   Carpentier, Pierre ^a   Dorandeu, Frederic ^a,b   Foquin, Annie ^a   Testylier, Guy ^a  

^a CENTRE DE RECHERCHES   (France)

^b Ecole du Val de Grace   (France)

Author keywords

brain histology; high resolution magic angle spinning; ketamine; midazolam; PLS DA; soman

Indexed keywords

ALANINE; ATROPINE; GLUTAMINE; GLYCEROPHOSPHORYLCHOLINE; INOSITOL; KETAMINE; LACTIC ACID; MIDAZOLAM; N ACETYLASPARTIC ACID; SOMAN; TAURINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT THERAPY; ARTICLE; CONTROLLED STUDY; DISCRIMINANT ANALYSIS; EPILEPTIC STATE; MALE; METABOLOMICS; MOUSE; NEUROPATHOLOGY; NEUROPROTECTION; NONHUMAN; PREDICTIVE VALUE; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTON HIGH RESOLUTION MAGIC ANGLE SPINNING NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; STATISTICAL MODEL; THERAPY DELAY;

ANIMALS; ANTICONVULSANTS; ATROPINE; BIOLOGICAL MARKERS; BRAIN; DRUG THERAPY, COMBINATION; KETAMINE; MAGNETIC RESONANCE SPECTROSCOPY; MALE; METABOLOME; MICE; MIDAZOLAM; MULTIVARIATE ANALYSIS; NEUROPROTECTIVE AGENTS; PRINCIPAL COMPONENT ANALYSIS; SOMAN; STATUS EPILEPTICUS;

EID: 84863613696     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr300291d     Document Type: Article

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