Longitudinal lung function declines among California flavoring manufacturing workers

American Journal of Industrial Medicine

Volumn 55, Issue 8, 2012, Pages 657-668

  Kreiss, Kathleen ^a   Fedan, Kathleen B ^a   Nasrullah, Muazzam ^a,b,e   Kim, Thomas J ^b,c,f   Materna, Barbara L ^c   Prudhomme, Janice C ^c,g   Enright, Paul L ^d  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^c CALIFORNIA DEPARTMENT OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF ARIZONA   (United States)

^e CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^f California Tribal Epidemiology Center   (United States)

^g Department of Industrial Relations   (United States)

Author keywords

Bronchiolitis obliterans; Diacetyl; Flavoring; Spirometry; Surveillance

Indexed keywords

2,3 BUTANEDIONE; FLAVORING AGENT;

ADOLESCENT; ADULT; AGED; ARTICLE; BRONCHIOLITIS OBLITERANS; CHEMICALLY INDUCED DISORDER; FEMALE; FORCED EXPIRATORY VOLUME; HEALTH SURVEY; HUMAN; INDUSTRY; LONGITUDINAL STUDY; MALE; MIDDLE AGED; OCCUPATIONAL DISEASE; OCCUPATIONAL EXPOSURE; PATHOPHYSIOLOGY; QUESTIONNAIRE; SPIROMETRY; STANDARD; STATISTICS; UNITED STATES;

ADOLESCENT; ADULT; AGED; BRONCHIOLITIS OBLITERANS; CALIFORNIA; DIACETYL; FEMALE; FLAVORING AGENTS; FORCED EXPIRATORY VOLUME; HUMANS; INDUSTRY; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; OCCUPATIONAL DISEASES; OCCUPATIONAL EXPOSURE; POPULATION SURVEILLANCE; QUESTIONNAIRES; SPIROMETRY; YOUNG ADULT;

EID: 84863575608     PISSN: 02713586     EISSN: 10970274     Source Type: Journal    
DOI: 10.1002/ajim.21013     Document Type: Article

References (25)

1. AARC (American Association for Respiratory Care). 2010. AARC online spirometry certificate. (accessed 4/9/10).
2. Borg BM, Hartley MF, Fisher MT, Thompson BR. 2010. Spirometry training does not guarantee valid results. Respir Care 55(6): 689- 694.
3. California Department of Public Health, Occupational Health Branch. 2007. Medical surveillance for flavorings-related lung disease among flavor manufacturing workers in California [cited 2009 January 13]. Available from:
4. Day G, Le Bouf R, Grote A, Pendergrass S, Cummings K, Kreiss K, Kullman G. 2011. Identification and measurement of diacetyl substitutes in dry bakery mix production. J Occup Environ Hyg 8: 93- 103.
5. Dykstra BJ, Scanlon PD, Kester MM, Beck KC, Enright PL. 1999. Lung volumes in 4, 774 patients with obstructive lung disease. Chest 115(1): 68- 74.
6. Enright PL, Beck KC, Sherrill DL. 2004. Repeatability of spirometry in 18, 000 adult patients. Am J Respir Crit Care Med 169: 235- 238.
7. Enright PL, Skloot GS, Cox-Ganser JM, Udasin IG, Herbert R. 2010. Quality of spirometry performed by 13, 599 participants in the World Trade Center worker and volunteer medical screening program. Respir Care 55(3): 303- 309.
8. Flake GP, Kirby PJ, Price HC, Gage PS, Kelly FL, Palmer SM, Foley JF, Morgan DL. 2010. Bronchiolitis obliterans-like lesions in rats treated with diacetyl, acetoin, or acetyl propionyl by intratracheal instillation. Toxicol Sci 114(S-1): 316.
9. Hankinson JL, Odencrantz JR, Fedan KB. 1999. Spirometric reference values from a sample of the general U.S. population. Am J Respir Crit Care Med 159(1): 179- 187.
10. Harber P, Levine J, Bansal S. 2009. How frequently should workplace spirometry screening be performed? Optimization via analytic models. Chest 136(4): 1086- 1094.
11. 1 in individuals. Occup Environ Med 64: 701- 707.
12. Hnizdo E, Glindmeyer HW, Petsonk EL. 2010. Workplace spirometry monitoring for respiratory disease prevention: A methods review. Int J Tuberc Lung Dis 14(7): 796- 805.
13. Hubbs AF, Moseley AE, Goldsmith WT, Jackson MC, Kashon ML, Battelli LA, Schwegler-Berry D, Goravanahally MP, Frazer D, Fedan JS, Kreiss K, Castranova V. 2010. Airway epithelial toxicity of the flavoring agent, 2, 3-pentanedione. Toxicol Sci 114(S-1): 319.
14. Kim TJ, Materna BL, Prudhomme JC, Fedan K, Enright PL, Sahakian N, Windham G, Kreiss K. 2010. Industry-wide medical surveillance of California flavor manufacturing workers: Cross-sectional results. Am J Ind Med 53: 857- 865.
15. Kreiss K. 2007. Flavoring related bronchiolitis obliterans. Curr Opin Allergy Clin Immunol 7: 162- 167.
16. Leuppi JD, Miedinger D, Chhajed PN, Buess C, Schafroth S, Bucher HC, Tamm M. 2010. Quality of spirometry in primary care for case finding of airway obstruction in smokers. Respiration 79: 469- 474.
17. Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Crapo R, Enright P, van der Grinten CPM, Gustafsson P, Jensen R, Johnson DC, MacIntyre N, McKay R, Navajas D, Pedersen OF, Pellegrino R, Viegi G, Wanger J, for the ATS/ERS Task Force. 2005. Standardisation of spirometry. Eur Respir J 26(2): 319- 338.
18. Milstein A. 2009. Ending extra payment for "never events"-Stronger incentives for patients' safety. N Engl J Med 360(23a): 2388- 2390.
19. Morgan DL, Jokinen MP, Price HC, Gwinn WM, Palmer SM, Flake GP. 2011. Bronchial and bronchiolar fibrosis in rats exposed to 2, 3-pentanedione vapors: Implications for bronchiolitis obliterans in humans. Toxicol Path 2011: 1- 18. DOI: 10.1177/0192623311431946.
20. National Institute for Occupational Safety Health. 2010. Spirometry in the occupational setting: Spirometry longitudinal data analysis (SPIROLA) software. Atlanta, GA, USA: Centers for Disease Control and Prevention, NIOSH, Version 3.0, updated. November 2010. Available from: Accessed May 2011.
21. SAS. 2004. SAS/STAT user's guide, version 9.1 for windows. Cary, NC: SAS Institute, Inc.
22. Townsend MC, Occupational and Environmental Lung Disorders Committee. 2011. Spirometry in the occupational health setting-2011 update. J Occup Environ Med 53: 569- 584.
23. U.S. Code of Federal Regulations. 2002. Standards for privacy of individually identifiable health information. Title 45, Part 164.512(b).
24. 1 over six to twelve months: What change is abnormal? J Occup Environ Med 46(6): 591- 595.
25. 1 changes. Chest 130(2): 493- 499.