Magnetic resonance imaging in late-life depression: Vascular and glucocorticoid cascade hypotheses

British Journal of Psychiatry

Volumn 201, Issue 1, 2012, Pages 46-51

  Sexton, Claire E ^a   Le Masurier, Marisa ^b   Allan, Charlotte L ^a   Jenkinson, Mark ^c   McDermott, Lisa ^d   Kalu, Ukwuori G ^a   Herrmann, Lucie L ^e   Bradley, Kevin M ^f   Mackay, Clare E ^a   Ebmeier, Klaus P ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b Westmorland General Hospital   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^e NHS GREATER GLASGOW AND CLYDE   (United Kingdom)

^f OXFORD UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID;

ADULT; AGED; ARTICLE; BRAIN RADIATION; BRAIN SIZE; CLINICAL ARTICLE; CONTROLLED STUDY; DIFFUSION TENSOR IMAGING; FEMALE; FRACTIONAL ANISOTROPY; GRAY MATTER; HIPPOCAMPUS; HUMAN; LATE LIFE DEPRESSION; MALE; MEDIAL LONGITUDINAL FASCICULUS; NEUROIMAGING; VASCULAR BIOLOGY; VOXEL BASED MORPHOMETRY; WHITE MATTER;

AGE OF ONSET; AGED; BRAIN DISEASES; CEREBROVASCULAR DISORDERS; DEPRESSIVE DISORDER; FEMALE; GLUCOCORTICOIDS; HIPPOCAMPUS; HUMANS; LEUKOENCEPHALOPATHIES; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; ORGAN SIZE;

EID: 84863574506     PISSN: 00071250     EISSN: 14721465     Source Type: Journal    
DOI: 10.1192/bjp.bp.111.105361     Document Type: Article

References (68)

1. Alexopoulos GS. Frontostriatal and limbic dysfunction in late-life depression. Am J Geriatr Psychiatry 2002; 10: 687-95. (Pubitemid 35315704)
2. Sexton CE, Mackay CE, Ebmeier KP. A systematic review and meta-analysis of magnetic resonance imaging studies in late-life depression. Am J Geriatr Psychiatry 2012; Feb 29 (Epub ahead of print).
3. Sexton CE, Mackay CE, Ebmeier KP. A systematic review of diffusion tensor imaging studies in affective disorders. Biol Psychiatry 2009; 66: 814-23.
4. Sexton CE, Allan CL, Le Masurier M, McDermott LM, Kalu UG, Herrmann LL, et al. Magnetic resonance imaging in late-life depression: multi-modal examination of network disruption. Arch Gen Psychiatry 2012; in press.
5. Shimony JS, Sheline YI, D'Angelo G, Epstein AA, Benzinger TL, Mintun MA, et al. Diffuse microstructural abnormalities of normal-appearing white matter in late life depression: a diffusion tensor imaging study. Biol Psychiatry 2009; 66: 245-52.
6. Pantel J, Schroder J, Essig M, Popp D, Dech H, Knopp MV, et al. Quantitative magnetic resonance imaging in geriatric depression and primary degenerative dementia. J Affect Disord 1997; 42: 69-83. (Pubitemid 27145473)
7. Taylor WD, Steffens DC, Payne ME, MacFall JR, Marchuk DA, Svenson IK, et al. Influence of serotonin transporter promoter region polymorphisms on hippocampal volumes in late-life depression. Arch Gen Psychiatry 2005; 62: 537-44. (Pubitemid 40628883)
8. Avila R, Ribeiz S, Duran FL, Arrais JP, Moscoso MA, Bezerra DM, et al. Effect of temporal lobe structure volume on memory in elderly depressed patients. Neurobiol Aging 2009; 32: 1857-67.
9. Alexopoulos GS, Meyers BS, Young RC, Campbell S, Silbersweig D, Charlson M. 'Vascular depression' hypothesis. Arch Gen Psychiatry 1997; 54: 915-22. (Pubitemid 128719702)
10. Herrmann L, Lemasurier M, Ebmeier K. White matter hyperintensities in late life depression: a systematic review. J Neurol Neurosurg Psychiatry 2008; 79: 619-24. (Pubitemid 351829430)
11. Chen CS, Chen CC, Kuo YT, Chiang IC, Ko CH, Lin HF. Carotid intima-media thickness in late-onset major depressive disorder. Int J Geriatr Psychiatry 2006; 21: 36-42. (Pubitemid 43141494)
12. Smith PJ, Blumenthal JA, Babyak MA, Doraiswamy PM, Hinderliter A, Hoffman BM, et al. Intima-media thickness and age of first depressive episode. Biol Psychol 2009; 80: 361-4.
13. Thomas AJ, O'Brien JT, Davis S, Ballard C, Barber R, Kalaria RN, et al. Ischemic basis for deep white matter hyperintensities in major depression: a neuropathological study. Arch Gen Psychiatry 2002; 59: 785-92. (Pubitemid 35001143)
14. Thomas AJ, Perry R, Kalaria RN, Oakley A, McMeekin W, O'Brien JT. Neuropathological evidence for ischemia in the white matter of the dorsolateral prefrontal cortex in late-life depression. Int J Geriatr Psychiatry 2003; 18: 7-13. (Pubitemid 36131222)
15. Bae JN, MacFall JR, Krishnan KR, Payne ME, Steffens DC, Taylor WD. Dorsolateral prefrontal cortex and anterior cingulate cortex white matter alterations in late-life depression. Biol Psychiatry 2006; 60: 1356-63. (Pubitemid 44838529)
16. Sapolsky RM. Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders. Arch Gen Psychiatry 2000; 57: 925-35.
17. Sapolsky RM, Krey LC, McEwen BS. The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis. Endocr Rev 1986; 7: 284-301.
18. Bell-McGinty S, Butters MA, Meltzer CC, Greer PJ, Reynolds 3rd CF, Becker JT. Brain morphometric abnormalities in geriatric depression: long-term neurobiological effects of illness duration. Am J Psychiatry 2002; 159: 1424-7. (Pubitemid 34832728)
19. Sheline YI, Wang PW, Gado MH, Csernansky JG, Vannier MW. Hippocampal atrophy in recurrent major depression. Proc Natl Acad Sci USA 1996; 93: 3908-13. (Pubitemid 26144221)
20. Andreescu C, Butters MA, Begley A, Rajji T, Wu M, Meltzer CC, et al. Gray matter changes in late life depression - a structural MRI analysis. Neuropsychopharmacology 2008; 33: 2566-72.
21. Janssen J, Hulshoff Pol HE, de Leeuw FE, Schnack HG, Lampe IK, Kok RM, et al. Hippocampal volume and subcortical white matter lesions in late life depression: comparison of early and late onset depression. J Neurol Neurosurg Psychiatry 2007; 78: 638-40. (Pubitemid 46853904)
22. O'Brien JT, Lloyd A, McKeith I, Gholkar A, Ferrier N. A longitudinal study of hippocampal volume, cortisol levels, and cognition in older depressed subjects. Am J Psychiatry 2004; 161: 2081-90. (Pubitemid 39441410)
23. Weber K, Giannakopoulos P, Delaloye C, de Bilbao F, Moy G, Moussa A, et al. Volumetric MRI changes, cognition and personality traits in old age depression. J Affect Disord 2010; 124: 275-82.
24. Ashtari M, Greenwald BS, Kramer-Ginsberg E, Hu J, Wu H, Patel M, et al. Hippocampal/amygdala volumes in geriatric depression. Psychol Med 1999; 29: 629-38. (Pubitemid 29261351)
25. Steffens DC, Byrum CE, McQuoid DR, Greenberg DL, Payne ME, Blitchington TF, et al. Hippocampal volume in geriatric depression. Biol Psychiatry 2000; 48: 301-9. (Pubitemid 30645800)
26. Butters MA, Young JB, Lopez O, Aizenstein HJ, Mulsant BH, Reynolds 3rd CF, et al. Pathways linking late-life depression to persistent cognitive impairment and dementia. Dialogues Clin Neurosci 2008; 10: 345-57.
27. Caraci F, Copani A, Nicoletti F, Drago F. Depression and Alzheimer's disease: neurobiological links and common pharmacological targets. Eur J Pharmacol 2010; 626: 64-71.
28. Byers AL, Yaffe K. Depression and risk of developing dementia. Nat Rev Neurol 2011; 7: 323-31.
29. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (4th edn) (DSM-IV). APA, 1994.
30. D'Agostino RB, Wolf PA, Belanger AJ, Kannel WB. Stroke risk profile: adjustment for antihypertensive medication. The Framingham Study. Stroke 1994; 25: 40-3.
31. Hamilton M. Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol 1967; 6: 278-96.
32. Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, et al. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res 1982; 17: 37-49. (Pubitemid 13123113)
33. Mioshi E, Dawson K, Mitchell J, Arnold R, Hodges JR. The Addenbrooke's Cognitive Examination Revised (ACE-R): a brief cognitive test battery for dementia screening. Int J Geriatr Psychiatry 2006; 21: 1078-85. (Pubitemid 44762726)
34. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12: 189-98.
35. Sahakian BJ, Owen AM, Morant NJ, Eagger SA, Boddington S, Crayton L, et al. Further analysis of the cognitive effects of tetrahydroaminoacridine (THA) in Alzheimer's disease: assessment of attentional and mnemonic function using CANTAB. Psychopharmacology (Berl) 1993; 110: 395-401. (Pubitemid 23074561)
36. Wechsler D. Wechsler Adult Intelligence Scale. The Psychological Corporation, 1997.
37. McKenna P, Warrington EK. Testing for nominal dysphasia. J Neurol Neurosurg Psychiatry 1980; 43: 781-8. (Pubitemid 10018471)
38. Brandt J. The Hopkins verbal learning test: development of a new memory test with six equivalent forms. Clin Neuropsychol 1991; 5: 125-42.
39. Osterrieth PA. Le test de copie d'une figure complexe. Arch Psychol 1944; 30: 206-356.
40. Reitan R. Validity of the Trail Making Test as an indicator of organic brain damage. Percept Mot Skills 1958; 8: 271-6.
41. Sexton CE, McDermott L, Kalu UG, Herrmann LL, Bradley KM, Allan CL, et al. Exploring the pattern and neural correlates of neuropsychological impairment in late-life depression. Psychol Med 2011; Oct 26 (Epub ahead of print).
42. Lyness JM, Pearson JL, Lebowitz BD, Kupfer DJ. Age at onset or late-life depression: a research agenda report of a MacArthur Foundation-NIMH Workshop. Am J Geriatr Psychiatry 1994; 2: 4-8. (Pubitemid 24335188)
43. Smith SM, Jenkinson M, Woolrich MW, Beckmann CF, Behrens TE, Johansen-Berg H, et al. Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage 2004; 23 (suppl 1): S208-19. (Pubitemid 39421720)
44. Smith SM. Fast robust automated brain extraction. Hum Brain Mapp 2002; 17: 143-55. (Pubitemid 35253488)
45. Patenaude B, Smith SM, Kennedy DN, Jenkinson M. A Bayesian model of shape and appearance for subcortical brain segmentation. Neuroimage 2011; 56: 907-22.
46. Ashburner J, Friston KJ. Voxel-based morphometry - the methods. Neuroimage 2000; 11: 805-21. (Pubitemid 30437668)
47. Good CD, Johnsrude IS, Ashburner J, Henson RNA, Friston KJ, Frackowiak RSJ. A voxel-based morphometric study of ageing in 465 normal adult human brains. Neuroimage 2001; 14: 21-36. (Pubitemid 32552740)
48. Jenkinson M, Bannister P, Brady M, Smith S. Improved optimization for the robust and accurate linear registration and motion correction of brain images. Neuroimage 2002; 17: 825-41. (Pubitemid 35317016)
49. Jenkinson M, Smith S. A global optimisation method for robust affine registration of brain images. Med Image Anal 2001; 5: 143-56. (Pubitemid 35282800)
50. Andersson JLR, Jenkinson M, Smith S. Non-Linear Optimisation. FMRIB Technical Report TR07JA1. FMRIB, 2007 (www.fmrib.ox.ac.uk/analysis/ techrep/).
51. Andersson JLR, Jenkinson M, Smith S. Non-Linear Registration, aka Spatial Normalisation. FMRIB Technical Report TR07JA2. FMRIB, 2007 (www.fmrib.ox.ac.uk/ analysis/techrep/).
52. Rueckert D, Sonoda LI, Hayes C, Hill DL, Leach MO, Hawkes DJ. Nonrigid registration using free-form deformations: application to breast MR images. IEEE Trans Med Imaging 1999; 18: 712-21. (Pubitemid 32262025)
53. Nichols TE, Holmes AP. Nonparametric permutation tests for functional neuroimaging: a primer with examples. Hum Brain Mapp 2002; 15: 1-25. (Pubitemid 34020610)
54. Smith SM, Nichols TE. Threshold-free cluster enhancement: addressing problems of smoothing, threshold dependence and localisation in cluster inference. Neuroimage 2009; 44: 83-98.
55. Smith SM, Jenkinson M, Johansen-Berg H, Rueckert D, Nichols TE, Mackay CE, et al. Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data. Neuroimage 2006; 31: 1487-505.
56. Mori S, Wakana S, Nagae-Poetscher LM, van Zijl PCM. MRI Atlas of Human White Matter. Elsevier BV, 2005.
57. Thomas AJ, Kalaria RN, O'Brien JT. Depression and vascular disease: what is the relationship? J Affect Disord 2004; 79: 81-95. (Pubitemid 38340532)
58. Paranthaman R, Greenstein AS, Burns AS, Cruickshank JK, Heagerty AM, Jackson A, et al. Vascular function in older adults with depressive disorder. Biol Psychiatry 2010; 68: 133-9.
59. Richardson J, Kerr SR, Shaw F, Kenny RA, O'Brien JT, Thomas AJ. A study of orthostatic hypotension in late-life depression. Am J Geriatr Psychiatry 2009; 17: 996-9.
60. Vasudev A, O'Brien JT, Tan MP, Parry SW, Thomas AJ. A study of orthostatic hypotension, heart rate variability and baroreflex sensitivity in late-life depression. J Affect Disord 2011; 131: 374-8.
61. Gerritsen L, Comijs HC, van der Graaf Y, Knoops AJ, Penninx BW, Geerlings MI. Depression, hypothalamic pituitary adrenal axis, and hippocampal and entorhinal cortex volumes - the SMART medea study. Biol Psychiatry 2011; 70: 373-80.
62. McEwen BS. Central effects of stress hormones in health and disease: understanding the protective and damaging effects of stress and stress mediators. Eur J Pharmacol 2008; 583: 174-85.
63. Wang Z, Neylan TC, Mueller SG, Lenoci M, Truran D, Marmar CR, et al. Magnetic resonance imaging of hippocampal subfields in posttraumatic stress disorder. Arch Gen Psychiatry 2010; 67: 296-303.
64. Chen MC, Hamilton JP, Gotlib IH. Decreased hippocampal volume in healthy girls at risk of depression. Arch Gen Psychiatry 2010; 67: 270-6.
65. de Geus EJ, van't Ent D, Wolfensberger SP, Heutink P, Hoogendijk WJ, Boomsma DI, et al. Intrapair differences in hippocampal volume in monozygotic twins discordant for the risk for anxiety and depression. Biol Psychiatry 2007; 61: 1062-71. (Pubitemid 46551972)
66. Prusoff BA, Merikangas KR, Weissman MM. Lifetime prevalence and age of onset of psychiatric disorders: recall 4 years later. J Psychiatr Res 1988; 22: 107-17.
67. Wiener P, Alexopoulos GS, Kakuma T, Meyers BS, Rosenthal E, Chester J. The limits of history-taking in geriatric depression. Am J Geriatr Psychiatry 1997; 5: 116-25. (Pubitemid 27157395)
68. Koolschijn PCMP, van Haren NEM, Lensvelt-Mulders GJLM, Hulshoff Pol HE, Kahn RS. Brain volume abnormalities in major depressive disorder: a meta-analysis of magnetic resonance imaging studies. Hum Brain Mapp 2009; 30: 3719-35.