Modeling sickle hemoglobin fibers as one chain of coarse-grained particles

Journal of Biomechanics

Volumn 45, Issue 11, 2012, Pages 1947-1951

  Li, He ^a   Ha, Vi ^a   Lykotrafitis, George ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Depletion forces; HbS fiber model; Langevin thermostat; Van der Waals forces; Zippering mechanisms

Indexed keywords

BIOMECHANICAL PROPERTIES; COARSE GRAINED PARTICLES; DEPLETION FORCE; FIBER BUNDLES; FIBER MODEL; FIBER-FIBER INTERACTIONS; GEL FORMATION; LANGEVIN; MATERIAL PROPERTY; MECHANICAL BEHAVIOR; ONE CHAIN; RED BLOOD CELL; SICKLE CELL DISEASE; SINGLE-POINT MUTATION; SOLVENT FREE; TETRAMERS;

BIOMECHANICS; GENES; HEMOGLOBIN; MOLECULAR DYNAMICS; OLIGOMERS; VAN DER WAALS FORCES;

FIBERS;

HEMOGLOBIN S;

ARTICLE; BIOMECHANICS; COARSE GRAIN MOLECULAR DYNAMICS MODEL; ENZYME ACTIVITY; ERYTHROCYTE MEMBRANE; MODEL; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN POLYMERIZATION; SICKLE CELL ANEMIA;

ANEMIA, SICKLE CELL; COMPUTER SIMULATION; ERYTHROCYTES; HEMOGLOBINS; HUMANS; MODELS, CHEMICAL; MODELS, MOLECULAR; PARTICLE SIZE; PROTEIN CONFORMATION;

EID: 84863569242     PISSN: 00219290     EISSN: 18732380     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2012.05.016     Document Type: Article

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