New halogenated disinfection byproducts in swimming pool water and their permeability across skin

Environmental Science and Technology

Volumn 46, Issue 13, 2012, Pages 7112-7119

  Xiao, Feng ^a,c   Zhang, Xiangru ^a   Zhai, Hongyan ^a,d   Lo, Irene M C ^a   Tipoe, George L ^b   Yang, Mengting ^a   Pan, Yang ^a   Chen, Guanghao ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c UNIVERSITY OF MINNESOTA   (United States)

^d TIANJIN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 ,4-DICHLOROPHENOL; 2 ,6-DICHLORO-4-NITROPHENOL; ADVERSE EFFECT; DISINFECTION BY-PRODUCT; DISINFECTION BYPRODUCTS; HUMAN BODIES; HUMAN SKIN; PATHOGENIC INFECTIONS; POOL WATER; PRECURSOR-ION SCAN; SWIMMING POOL WATER; TRIPLE-QUADRUPOLE MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

BROMINE COMPOUNDS; BYPRODUCTS; CHLORINE; ELECTROSPRAY IONIZATION; HALOGENATION; LAKES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHENOLS; SWIMMING POOLS;

DISINFECTION;

2 BROMO 6 CHLORO 4 NITROPHENOL; 2 BROMOPHENOL; 2,4 DIBROMOPHENOL; 2,4 DICHLOROPHENOL; 2,6 DIBROMO 4 NITROPHENOL; 2,6 DICHLORO 4 NITROPHENOL; BROMIDE; CHLORINE; HALOPHENOL; NITROPHENOL; UNCLASSIFIED DRUG;

BROMIDE; CHLORINE; DISINFECTION; EPIDEMIOLOGY; INFECTIOUS DISEASE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PATHOGENICITY; PERMEABILITY; POOL; SKIN; SWIMMING; URINE;

ARTICLE; CHLORINATION; ELECTROSPRAY MASS SPECTROMETRY; EPIDERMIS; HUMAN; HUMAN TISSUE; SKIN PERMEABILITY; SWIMMING; SWIMMING POOL; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; URINE;

CHLORINE; DISINFECTANTS; DISINFECTION; HALOGENATION; HUMANS; NITROPHENOLS; PERMEABILITY; SKIN; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SWIMMING POOLS;

EID: 84863514759     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es3010656     Document Type: Article

References (40)

1. Walse, S. S.; Mitch, W. A. Nitrosamine carcinogens also swim in chlorinated pools Environ. Sci. Technol. 2008, 42 (4) 1032-1037
2. Weng, S. C.; Blatchley, E. R. Disinfection by-product dynamics in a chlorinated, indoor swimming pool under conditions of heavy use: National swimming competition Water Res. 2011, 45 (16) 5241-5248
3. Weaver, W. A.; Li, J.; Wen, Y. L.; Johnston, J.; Blatchley, M. R.; Blatchley, E. R. Volatile disinfection by-product analysis from chlorinated indoor swimming pools Water Res. 2009, 43 (13) 3308-3318
4. Richardson, S. D.; Plewa, M. J.; Wagner, E. D.; Schoeny, R.; DeMarini, D. M. Occurrence, genotoxicity, and carcinogenicity of regulated and emerging disinfection by-products in drinking water: A review and roadmap for research Mutat. Res. 2007, 636 (1-3) 178-242
5. Plewa, M. J.; Wagner, E. D.; Mitch, W. A. Comparative mammalian cell cytotoxicity of water concentrates from disinfected recreational pools Environ. Sci. Technol. 2011, 45 (9) 4159-4165
6. Bernard, A.; Carbonnelle, S.; de Burbure, C.; Michel, O.; Nickmilder, M. Chlorinated pool attendance, atopy, and the risk of asthma during childhood Environ. Health Perspect. 2006, 114 (10) 1567-1573
7. Villanueva, C. M.; Cantor, K. P.; Grimalt, J. O.; Malats, N.; Silverman, D.; Tardon, A.; Garcia-Closas, R.; Serra, C.; Carrato, A.; Castano-Vinyals, G.; Marcos, R.; Rothman, N.; Real, F. X.; Dosemeci, M.; Kogevinas, M. Bladder cancer and exposure to water disinfection by-products through ingestion, bathing, showering, and swimming in pools Am. J. Epidemiol. 2007, 165 (2) 148-156
8. Liviac, D.; Wagner, E. D.; Mitch, W. A.; Altonji, M. J.; Plewa, M. J. Genotoxicity of water concentrates from recreational pools after various disinfection methods Environ. Sci. Technol. 2010, 44 (9) 3527-3532
9. Zwiener, C.; Richardson, S. D.; De Marini, D. M.; Grummt, T.; Glauner, T.; Frimmel, F. H. Drowning in disinfection byproducts? Assessing swimming pool water Environ. Sci. Technol. 2007, 41 (2) 363-372
10. Zhang, X. R.; Minear, R. A.; Barrett, S. E. Characterization of high molecular weight disinfection byproducts from chlorination of humic substances with/without coagulation pretreatment using UF-SEC-ESl-MS/MS Environ. Sci. Technol. 2005, 39 (4) 963-972
11. Zhang, X. R.; Talley, J. W.; Boggess, B.; Ding, G. Y.; Birdsell, D. Fast selective detection of polar brominated disinfection byproducts in drinking water using precursor ion scans Environ. Sci. Technol. 2008, 42 (17) 6598-6603
12. Zhai, H. Y.; Zhang, X. R. A new method for differentiating adducts of common drinking water DBPs from higher molecular weight DBPs in electrospray ionization-mass spectrometry analysis Water Res. 2009, 43 (8) 2093-2100
13. Ding, G. Y.; Zhang, X. R. A picture of polar iodinated disinfection byproducts in drinking water by (UPLC/)ESI-tqMS Environ. Sci. Technol. 2009, 43 (24) 9287-9293
14. USEPA Office of Pollution Prevention and Toxics, and Occupational Safety and Health Administration http://www.epa.gov/oppt/pubs/dcpfinal2-15.pdf (accessed February 2012).
15. Zhang, X. Y.; Zha, J. M.; Li, W.; Yang, L. H.; Wang, Z. J. Effects of 2,4-dichlorophenol on the expression of vitellogenin and estrogen receptor genes and physiology impairments in Chinese rare minnow (Gobiocypris rarus) Environ. Toxicol. 2008, 23 (6) 694-701
16. Aoyama, H.; Hojo, H.; Takahashi, K. L.; Shimizu, N.; Araki, M.; Harigae, M.; Tanaka, N.; Shirasaka, N.; Kuwahara, M.; Nakashima, N.; Yamamoto, E.; Saka, M.; Teramoto, S. A two-generation reproductive toxicity study of 2,4-dichlorophenol in rats J. Toxicol. Sci. 2005, 30, 59-78
17. Levesque, B.; Ayotte, P.; LeBlanc, A.; Dewailly, E.; Prud'Homme, D.; Lavoie, R.; Allaire, S.; Levallois, P. Evaluation of dermal and respiratory chloroform exposure in humans Environ. Health Perspect. 1994, 102 (12) 1082-1087
18. Lindstrom, A. B.; Pleil, J. D.; Berkoff, D. C. Alveolar breath sampling and analysis to assess trihalomethane exposures during competitive swimming training Environ. Health Perspect. 1997, 105 (6) 636-642
19. Xu, X.; Mariano, T. M.; Laskin, J. D.; Weisel, C. P. Percutaneous absorption of trihalomethanes, haloacetic acids, and haloketones Toxicol. Appl. Pharmacol. 2002, 184 (1) 19-26
20. Seki, T.; Morimatsu, S.; Nagahori, H.; Morohashi, M. Free residual chlorine in bathing water reduces the water-holding capacity of the stratum corneum in atopic skin J. Dermatol. 2003, 30 (3) 196-202
21. APHA, AWWA, and WEF. Standard Methods for the Examination of Water and Wastewater, 19 th ed.; Washington, DC, 1995.
22. Hua, G. H.; Reckhow, D. A. Determination of TOCl, TOBr and TOI in drinking water by pyrolysis and off-line ion chromatography Anal. Bioanal. Chem. 2006, 384 (2) 495-504
23. Li, Y.; Zhang, X. R.; Shang, C. Effect of reductive property of activated carbon on total organic halogen analysis Environ. Sci. Technol. 2010, 44 (6) 2105-2111
24. Richardson, S. D.; Thruston, A. D.; Rav-Acha, C.; Groisman, L.; Popilevsky, I.; Juraev, O.; Glezer, V.; McKague, A. B.; Plewa, M. J.; Wagner, E. D. Tribromopyrrole, brominated acids, and other disinfection byproducts produced by disinfection of drinking water rich in bromide Environ. Sci. Technol. 2003, 37 (17) 3782-3793
25. The Hair Loss Site. http://www.thehairlosssite.com (accessed September 2011).
26. Zhang, X. R.; Echigo, S.; Minear, R. A.; Plewa, M. J. Characterization and comparison of disinfection by-products from using four major disinfectants. In Natural Organic Matter and Disinfection By-Products: Characterization and Control in Drinking Water; Barrett, S. E.; Krasner, S. W.; Amy, G. L., Eds.; American Chemical Society: Washington, DC, 2000; pp 299-314.
27. Zhai, H. Y.; Zhang, X. R. Formation and decomposition of new and unknown polar brominated disinfection byproducts during chlorination Environ. Sci. Technol. 2011, 45 (6) 2194-2201
28. Michalowicz, J.; Stufka-Olczyk, J.; Milczarek, A.; Michniewicz, M. Analysis of annual fluctuations in the content of phenol, chlorophenols and their derivatives in chlorinated drinking waters Environ. Sci. Pollut. Res. 2011, 18 (7) 1174-1183
29. Richardson, S. D.; DeMarini, D. M.; Kogevinas, M.; Fernandez, P.; Marco, E.; Lourencetti, C.; Balleste, C.; Heederik, D.; Meliefste, K.; McKague, A. B.; Marcos, R.; Font-Ribera, L.; Grimalt, J. O.; Villanueva, C. M. What's in the pool? A comprehensive identification of disinfection by-products and assessment of mutagenicity of chlorinated and brominated swimming pool water Environ. Health Perspect. 2010, 118 (11) 1523-1530
30. Plewa, M. J.; Wagner, E. D.; Muellner, M. G.; Hsu, K. M.; Richardson, S. D. Comparative mammalian cell toxicity of N-DBPs and C-DBPs. In Occurrence, Formation, Health Effects and Control of Disinfection by-Products in Drinking Water; Karanfil, T.; Krasner, S. W.; Westerhoff, P.; Xie, Y., Eds.; American Chemical Society: Washington, DC, 2008; Vol. 995, pp 36-50.
31. Erdinger, L.; Kirsch, F.; Sonntag, H. G. Potassium as an indicator of anthropogenic contamination of swimming pool water Int. J. Hyg. Environ. Health 1997, 200 (4) 297-308
32. Putnam, D. F. Composition and Concentrative Properties of Human Urine; National Aeronautics and Space Administration: Washington, DC, 1971.
33. Guo, L. D.; Lehner, J. K.; White, D. M.; Garland, D. S. Heterogeneity of natural organic matter from the Chena River, Alaska Water Res. 2003, 37 (5) 1015-1022
34. Polprasert, C. Organic Waste Recycling; John Wiley & Sons, Inc.: New York, NY, 1989.
35. Bieniek, G. Simultaneous determination of 2-methoxyphenol, 2-methoxy-4-methylphenol, 2,6-dimethoxyphenol and 4′-hydroxy-3′- methoxyacetophenone in urine by capillary gas chromatography J. Chromatogr., B 2003, 795 (2) 389-394
36. Hallem, E. A.; Fox, A. N.; Zwiebel, L. J.; Carlson, J. R. Olfaction: Mosquito receptor for human-sweat odorant Nature 2004, 427, 212-213
37. Larson, R. A.; Weber, E. J. Reaction Mechanisms in Environmental Organic Chemistry; Lewis Publishers: Boca Raton, FL, 1994.
38. Ge, F.; Zhu, L. Z.; Chen, H. R. Effects of pH on the chlorination process of phenols in drinking water J. Hazard. Mater. 2006, 133 (1-3) 99-105
39. Wohnsland, F.; Faller, B. High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes J. Med. Chem. 2001, 44 (6) 923-930
40. Boutwell, R. K.; Bosch, D. K. The tumor-promoting action of phenol and related compounds for mouse skin Cancer Res. 1959, 19 (4) 413-424