Apoptotic cell death correlates with ROS overproduction and early cytokine expression after hypoxia-ischemia in fetal lambs

Reproductive Sciences

Volumn 19, Issue 7, 2012, Pages 754-763

  Alonso Alconada, Daniel ^a   Hilario, Enrique ^a   Álvarez, Francisco José ^b   Álvarez, Antonia ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^b HOSPITAL DE CRUCES   (Spain)

Author keywords

apoptosis; cytokines; fetal lamb; hypoxia ischemia; oxidative damage

Indexed keywords

CELL ADHESION MOLECULE; CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN REGION; CELL DEATH; CONTROLLED STUDY; CYTOKINE PRODUCTION; FETUS; FLOW CYTOMETRY; LAMB; NEWBORN HYPOXIA; NONHUMAN; PERINATAL ASPHYXIA; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; APOPTOSIS; BRAIN; CELL ADHESION MOLECULES; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; FETAL HYPOXIA; HYPOXIA-ISCHEMIA, BRAIN; NERVE TISSUE PROTEINS; NEURONS; ORGAN SPECIFICITY; RANDOM ALLOCATION; REACTIVE OXYGEN SPECIES; SHEEP, DOMESTIC; UP-REGULATION;

EID: 84863508843     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719111432868     Document Type: Article

References (39)

1. du Plessis AJ, Volpe JJ. Perinatal brain injury in the preterm and term newborn. Curr Opin Neurol. 2002 ; 15 (2). 151-157
2. Hamrick SE, Ferriero DM. The injury response in the term newborn brain: can we neuroprotect?. Curr Opin Neurol. 2003 ; 16 (2). 147-154
3. Lawn JE, Cousens S. Zupan J. 4 million neonatal deaths: when? where? why?. Lancet. 2005 ; 365 (9462). 891-900
4. Yager JY, Armstrong EA, Black AM. Treatment of the term newborn with brain injury: simplicity as the mother of invention. Pediatr Neurol. 2009 ; 40 (3). 237-243
5. Buonocore G, Perrone S, Bracci R. Free radicals and brain damage in the newborn. Biol Neonate. 2001 ; 79 (3-4). 180-186
6. Kumar A, Mittal R, Khanna H, Basu S. Free radical injury and blood-brain barrier permeability in hypoxic-ischemic encephalopathy. Pediatrics. 2008 ; 122 (3). 722-727
7. McLean C, Ferriero D. Mechanisms of hypoxic-ischemic injury in the term infant. Semin Perinatol. 2004 ; 28 (6). 425-432
8. Szaflarski J, Burtrum D, Silverstein FS. Cerebral hypoxia-ischemia stimulates cytokine gene expression in perinatal rats. Stroke. 1995 ; 26 (6). 1093-1100
9. Stanimirovic D, Satoh K. Inflammatory mediators of cerebral endothelium: a role in ischemic brain inflammation. Brain Pathol. 2000 ; 10 (1). 113-126
10. Cai Z, Lin S, Pang Y, Rhodes PG. Brain injury induced by intracerebral injection of interleukin-1beta and tumor necrosis factor-alpha in the neonatal rat. Pediatr Res. 2004 ; 56 (3). 377-384
11. Basu A, Lazovic J, Krady JK, Mauger DT, Rothstein RP, Smith MB, et al. Interleukin-1 and the interleukin-1 type 1 receptor are essential for the progressive neurodegeneration that ensues subsequent to a mild hypoxic/ischemic injury. J Cereb Blood Flow Metab. 2005 ; 25 (1). 17-29
12. Jurewicz A, Matysiak M, Tybor K, Kilianek L, Raine CS, Selmaj K. Tumour necrosis factor-induced death of adult human oligodendrocytes is mediated by apoptosis inducing factor. Brain. 2005 ; 128 (pt 11). 2675-2688
13. Buttini M, Sauter A, Boddeke HW. Induction of interleukin-1 beta mRNA after focal cerebral ischaemia in the rat. Brain Res Mol Brain Res. 1994 ; 23 (1-2). 126-134
14. Liu T, Clark RK, McDonnell PC, Young PR, White RF, Barone FC, et al. Tumor necrosis factor-alpha expression in ischemic neurons. Stroke. 1994 ; 25 (7). 1481-1488
15. Wang X, Yue TL, Barone FC, White RF, Gagnon RC, Feuerstein GZ. Concomitant cortical expression of TNF-alpha and IL-1 beta mRNAs follows early response gene expression in transient focal ischemia. Mol Chem Neuropathol. 1994 ; 23 (2-3). 103-114
16. Suzuki S, Tanaka K, Nogawa S, Nagata E, Ito D, Dembo T, et al. Temporal profile and cellular localization of interleukin-6 protein after focal cerebral ischemia in rats. J Cereb Blood Flow Metab. 1999 ; 19 (11). 1256-1262
17. Zhu Y, Saito K, Murakami Y, Asano M, Iwakura Y, Seishima M. Early increase in mRNA levels of pro-inflammatory cytokines and their interactions in the mouse hippocampus after transient global ischemia. Neurosci Lett. 2006 ; 393 (2-3). 122-126
18. Offner H, Subramanian S, Parker SM, Afentoulis ME, Vandenbark AA, Hurn PD. Experimental stroke induces massive, rapid activation of the peripheral immune system. J Cereb Blood Flow Metab. 2006 ; 26 (5). 654-665
19. Yager JY. Animal models of hypoxic-ischemic brain damage in the newborn. Semin Pediatr Neurol. 2004 ; 11 (1). 31-46
20. Rice JE, Vannucci RC, Brierley JB. The influence of immaturity on hypoxic-ischemic brain damage in the rat. Ann Neurol. 1981 ; 9 (2). 131-141
21. Raju TNK. Some animal models for the study of perinatal asphyxia. Biol Neonate. 1992 ; 62 (4). 202-214
22. Hilario E, Rey MC, Goñi F, et al. Cerebral blood flow and morphological changes after hypoxic-ischemic injury in preterm lambs. Acta Paediatr. 2005 ; 94 (7). 903-911
23. Goñi-de-Cerio F, Alvarez A, Caballero A, et al. Early cell death in the brain of fetal preterm lambs after hypoxic-ischemic injury. Brain Res. 2007 ; 1151: 161-171
24. Alonso-Alconada D, Alvarez FJ, Alvarez A, et al. The cannabinoid receptor agonist WIN 55,212-2 reduces the initial cerebral damage after hypoxic-ischemic injury in fetal lambs. Brain Res. 2010 ; 1362: 150-159
25. Ikeda T, Murata Y, Quilligan EJ, et al. Physiologic and histologic changes in near-term fetal lambs exposed to asphyxia by partial umbilical cord occlusion. Am J Obstet Gynecol. 1998 ; 178 (1pt 1). 24-32
26. Ikeda T, Choi BH, Yee S, Murata Y, Quilligan EJ. Oxidative stress, brain white matter damage and intrauterine asphyxia in fetal lambs. Int J Dev Neurosci. 1999 ; 17 (1). 1-14
27. Weis SN, Schunck RV, Pettenuzzo LF, et al. Early biochemical effects after unilateral hypoxia-ischemia in the immature rat brain. Int J Dev Neurosci. 2011 ; 29 (2). 115-120
28. Solberg R, Andresen JH, Escrig R, Vento M, Saugstad OD. Resuscitation of hypoxic newborn piglets with oxygen induces a dose-dependent increase in markers of oxidation. Pediatr Res. 2007 ; 62 (5). 559-563
29. Solberg R, Løberg EM, Andresen JH, et al. Resuscitation of newborn piglets. short-term influence of FiO2 on matrix metalloproteinases, caspase-3 and BDNF. PLoS One. 2010 ; 5 (12). e14261
30. Blomgren K, Hagberg H. Free radicals, mitochondria, and hypoxia-ischemia in the developing brain. Free Radic Biol Med. 2006 ; 40 (3). 388-397
31. Shalak LF, Laptook AR, Jafri HS, Ramilo O, Perlman JM. Clinical chorioamnionitis, elevated cytokines, and brain injury in term infants. Pediatrics. 2002 ; 110 (4). 673-680
32. Zheng Z, Yenari M.A. Post-ischemic inflammation: molecular mechanisms and therapeutic implications. Neurol Res. 2004 ; 26 (8). 884-892
33. Roelfsema V, Bennet L, George S, et al. Window of opportunity of cerebral hypothermia for postischemic white matter injury in the near-term fetal sheep. J Cereb Blood Flow Metab. 2004 ; 24 (8). 877-886
34. Wajant H, Pfizenmaier K, Scheurich P. Tumor necrosis factor signaling. Cell Death Differ. 2003 ; 10 ((1)). :45-65
35. Martin D, Chinookoswong N, Miller G. The interleukin-1 receptor antagonist (rhil-1ra) protects against cerebral infarction in a rat model of hypoxia-ischemia. Exp Neurol. 1994 ; 130 (2). 362-367
36. Zhang RL, Chopp M, Li Y, Zaloga C, Jiang N, Jones ML, et al. Anti-ICAM-1 antibody reduces ischemic cell damage after transient middle cerebral artery occlusion in the rat. Neurology. 1994 ; 44 (9). 1747-1751
37. Carloni S, Mazzoni E, Cimino M, et al. Simvastatin reduces caspase-3 activation and inflammatory markers induced by hypoxia-ischemia in the newborn rat. Neurobiol Dis. 2006 ; 21 (1). 119-126
38. Vemuganti R, Dempsey RJ, Bowen KK. Inhibition of intercellular adhesion molecule-1 protein expression by antisense oligonucleotides is neuroprotective after transient middle cerebral artery occlusion in rat. Stroke. 2004 ; 35 (1). 179-184
39. Wang X, Feuerstein GZ. Induced expression of adhesion molecules following focal brain ischemia. J Neurotrauma. 1995 ; 12 (5). 825-832