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Volumn 9, Issue 3, 2012, Pages 163-169

Alpha-glucosidase inhibitors 2012-cardiovascular considerations and trial evaluation

Author keywords

Acarbose Evaluation Trial; Alpha glucosidase inhibitors; glycaemic variability; myocardial infarction; postprandial hyperglycaemia; STOP NIDDM Trial

Indexed keywords

ACARBOSE; ALPHA GLUCOSIDASE INHIBITOR; HEMOGLOBIN A1C; MIGLITOL; VOGLIBOSE;

EID: 84863482399     PISSN: 14791641     EISSN: 17528984     Source Type: Journal    
DOI: 10.1177/1479164112441524     Document Type: Review
Times cited : (122)

References (54)
  • 3
    • 65649106228 scopus 로고    scopus 로고
    • Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: A meta-analysis of randomised controlled trials
    • Ray KK, Seshasai SR, Wijesuriya S, et al. Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: a meta-analysis of randomised controlled trials. Lancet 2009; 373: 1765-1772.
    • (2009) Lancet , vol.373 , pp. 1765-1772
    • Ray, K.K.1    Seshasai, S.R.2    Wijesuriya, S.3
  • 4
    • 70349881450 scopus 로고    scopus 로고
    • Intensive glucose control and macrovascular outcomes in type 2 diabetes
    • Turnbull FM, Abraira C, Anderson RJ, et al. Intensive glucose control and macrovascular outcomes in type 2 diabetes. Diabetologia 2009; 52: 2288-2298.
    • (2009) Diabetologia , vol.52 , pp. 2288-2298
    • Turnbull, F.M.1    Abraira, C.2    Anderson, R.J.3
  • 5
    • 77951735232 scopus 로고    scopus 로고
    • Effects of intensive blood-pressure control in type 2 diabetes mellitus
    • Cushman WC, Evans GW, Byington RP, et al. Effects of intensive blood-pressure control in type 2 diabetes mellitus. N Engl J Med 2010; 362: 1575-1585.
    • (2010) N Engl J Med , vol.362 , pp. 1575-1585
    • Cushman, W.C.1    Evans, G.W.2    Byington, R.P.3
  • 6
    • 77954374543 scopus 로고    scopus 로고
    • Tight blood pressure control and cardiovascular outcomes among hypertensive patients with diabetes and coronary artery disease
    • Cooper-DeHoff RM, Gong Y, Handberg EM, et al. Tight blood pressure control and cardiovascular outcomes among hypertensive patients with diabetes and coronary artery disease. JAMA 2010; 304: 61-68.
    • (2010) JAMA , vol.304 , pp. 61-68
    • Cooper-DeHoff, R.M.1    Gong, Y.2    Handberg, E.M.3
  • 7
    • 79952373965 scopus 로고    scopus 로고
    • Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes
    • Haller H, Ito S, Izzo Jr JL, et al. Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes. N Engl J Med 2011; 364: 907-917.
    • (2011) N Engl J Med , vol.364 , pp. 907-917
    • Haller, H.1    Ito, S.2    Izzo Jr., J.L.3
  • 8
    • 34250212715 scopus 로고    scopus 로고
    • Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
    • Nissen SE and Wolski K. Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med 2007; 356: 2457-2471. (Pubitemid 46919772)
    • (2007) New England Journal of Medicine , vol.356 , Issue.24 , pp. 2457-2471
    • Nissen, S.E.1    Wolski, K.2
  • 9
    • 84863466608 scopus 로고    scopus 로고
    • Type 2 diabetes: Newer agents
    • National Institute for Health and Clinical Excellence London: NICE
    • National Institute for Health and Clinical Excellence. Type 2 diabetes: Newer agents. NICE short clinical guideline 87. London: NICE, 2009; pp. 1-102.
    • (2009) NICE Short Clinical Guideline , vol.87 , pp. 1-102
  • 11
    • 80052522584 scopus 로고    scopus 로고
    • Prognostic implications of glucose-lowering treatment in patients with acute myocardial infarction and diabetes: Experiences from an extended follow-up of the Diabetes Mellitus Insulin-Glucose Infusion in Acute Myocardial Infarction (DIGAMI) 2 Study
    • Mellbin LG, Malmberg K, Norhammar A, et al. Prognostic implications of glucose-lowering treatment in patients with acute myocardial infarction and diabetes: experiences from an extended follow-up of the Diabetes Mellitus Insulin-Glucose Infusion in Acute Myocardial Infarction (DIGAMI) 2 Study. Diabetologia 2011; 54: 1308-1317.
    • (2011) Diabetologia , vol.54 , pp. 1308-1317
    • Mellbin, L.G.1    Malmberg, K.2    Norhammar, A.3
  • 12
    • 79958197888 scopus 로고    scopus 로고
    • Mortality and cardiovascular risk associated with different insulin secretagogues compared with metformin in type 2 diabetes, with or without a previous myocardial infarction: A nationwide study
    • Schramm TK, Gislason GH, Vaag A, et al. Mortality and cardiovascular risk associated with different insulin secretagogues compared with metformin in type 2 diabetes, with or without a previous myocardial infarction: a nationwide study. Eur H J 2011; 32: 1900-1908.
    • (2011) Eur H J , vol.32 , pp. 1900-1908
    • Schramm, T.K.1    Gislason, G.H.2    Vaag, A.3
  • 14
    • 38449121158 scopus 로고    scopus 로고
    • Diabetes mellitus: Everyday practice
    • Desai A and Tandon N. Diabetes mellitus: everyday practice. Natl Med J India 2007; 20: 192-198.
    • (2007) Natl Med J India , vol.20 , pp. 192-198
    • Desai, A.1    Tandon, N.2
  • 16
    • 12644262888 scopus 로고
    • Pharmacology of alpha-glucosidase-inhibitors
    • Vasselli J, Maggio C, Scriabine A (eds) Branford, CT, USA: Neva Press
    • Bischoff H. Pharmacology of alpha-glucosidase-inhibitors. In: Vasselli J, Maggio C, Scriabine A (eds) Drugs in development: alpha-glucosidase inhibition: potential use in diabetes. Branford, CT, USA: Neva Press, 1993, pp. 3-13.
    • (1993) Drugs in Development: Alpha-glucosidase Inhibition: Potential Use in Diabetes , pp. 3-13
    • Bischoff, H.1
  • 17
    • 0029147672 scopus 로고
    • Glucagon-like peptide 1 (7-36 amide) secretion in response to luminal sucrose from the upper and the lower gut. A study using alpha-glucosidase inhibition (acarbose)
    • Qualmann C, Nauck MA, Holst JJ, et al. Glucagon-like peptide 1 (7-36 amide) secretion in response to luminal sucrose from the upper and the lower gut. A study using alpha-glucosidase inhibition (acarbose). Scand J Gastroenterol 1995; 30: 892-896.
    • (1995) Scand J Gastroenterol , vol.30 , pp. 892-896
    • Qualmann, C.1    Nauck, M.A.2    Holst, J.J.3
  • 18
    • 0028784208 scopus 로고
    • Voglibose (AO-128) is an efficient alpha-glucosidase inhibitor and mobilizes the endogenous GLP-1 reserve
    • Göke B, Fuder H, Wieckhorst G, et al. Voglibose (AO-128) is an efficient alpha-glucosidase inhibitor and mobilizes the endogenous GLP-1 reserve. Digestion 1995; 56: 493-501.
    • (1995) Digestion , vol.56 , pp. 493-501
    • Göke, B.1    Fuder, H.2    Wieckhorst, G.3
  • 20
    • 11844294865 scopus 로고    scopus 로고
    • Alpha-Glucosidase inhibitors for patients with type 2 diabetes: Results from a Cochrane systematic review and meta-analysis
    • DOI 10.2337/diacare.28.1.154
    • Van de Laar FA, Lucassen PL, Akkermans RP, et al. Alpha-glucosdase inhibitors for patients with type 2 diabetes: results from a Cochrane systematic review and meta-analysis. Diabetes Care 2005; 28: 154-163. (Pubitemid 40095800)
    • (2005) Diabetes Care , vol.28 , Issue.1 , pp. 154-163
    • Van De, L.F.A.1    Lucassen, P.L.2    Akkermans, R.P.3    Van De, L.E.H.4    Rutten, G.E.5    Van Weel, C.6
  • 21
    • 40149101914 scopus 로고    scopus 로고
    • Acarbose: Oral antidiabetes drug with additional cardiovascular benefits
    • DOI 10.1586/14779072.6.2.153
    • Hanefeld M and Schaper F. Acarbose: oral anti-diabetes drug with additional cardiovascular benefits. Expert Rev Cardiovasc Ther 2008; 6: 153-163. (Pubitemid 351372584)
    • (2008) Expert Review of Cardiovascular Therapy , vol.6 , Issue.2 , pp. 153-163
    • Hanefeld, M.1    Schaper, F.2
  • 22
    • 41749106662 scopus 로고    scopus 로고
    • Comparison of vildagliptin and acarbose monotherapy in patients with type 2 diabetes: A 24-week, double-blind, randomized trial
    • DOI 10.1111/j.1464-5491.2008.02391.x
    • Pan C, Yang W, Barona JP, et al. Comparison of vildagliptin and acarbose monotherapy in patients with type 2 diabetes: a 24-week, double-blind, randomized trial. Diabet Med 2008; 25: 435-441. (Pubitemid 351490110)
    • (2008) Diabetic Medicine , vol.25 , Issue.4 , pp. 435-441
    • Pan, C.1    Yang, W.2    Barona, J.P.3    Wang, Y.4    Niggli, M.5    Mohideen, P.6    Wang, Y.7    Foley, J.E.8
  • 23
    • 70349911614 scopus 로고    scopus 로고
    • Therapeutic experience with acarbose in the treatment of type 2 diabetes
    • Schnell O, Chan J and Josse RG. Therapeutic experience with acarbose in the treatment of type 2 diabetes. Diabetes Metab & the Heart 2009; 18: 409-415.
    • (2009) Diabetes Metab & the Heart , vol.18 , pp. 409-415
    • Schnell, O.1    Chan, J.2    Josse, R.G.3
  • 24
    • 79959774659 scopus 로고    scopus 로고
    • Postprandial hyperglycemia and glycemic variability. Should we care?
    • Standl E, Schnell O and Ceriello A. Postprandial hyperglycemia and glycemic variability. Should we care? Diabetes Care 2011; 34(Suppl 2): 120-127.
    • (2011) Diabetes Care , vol.34 , Issue.SUPPL. 2 , pp. 120-127
    • Standl, E.1    Schnell, O.2    Ceriello, A.3
  • 25
    • 0032902850 scopus 로고    scopus 로고
    • The relationship between glucose and incident cardiovascular events: A metaregression analysis of published data from 20 studies of 95,783 individuals followed for 12.4 years
    • DOI 10.2337/diacare.22.2.233
    • Coutinho M, Gerstein HC, Wang Y, et al. The relationship between glucose and incident cardiovascular events: a metaregression analysis of published data from 20 studies of 95,783 individuals followed for 12.4 years. Diabetes Care 1999; 22: 233-240. (Pubitemid 29056916)
    • (1999) Diabetes Care , vol.22 , Issue.2 , pp. 233-240
    • Coutinho, M.1    Gerstein, H.C.2    Wang, Y.3    Yusuf, S.4
  • 26
    • 0033592101 scopus 로고    scopus 로고
    • Glucose tolerance and mortality: Comparison of WHO and American Diabetes Association diagnostic criteria. Diabetes epidemiology: collaborative analysis of diagnsotic criteria in Europe
    • The DECODE Study Group; European Diabetes Epidemiology Group
    • The DECODE Study Group; European Diabetes Epidemiology Group. Glucose tolerance and mortality: comparison of WHO and American Diabetes Association diagnostic criteria. Diabetes epidemiology: collaborative analysis of diagnsotic criteria in Europe. Lancet 1999; 354: 617-621.
    • (1999) Lancet , vol.354 , pp. 617-621
  • 27
    • 1842833576 scopus 로고    scopus 로고
    • Hyperglycemia and mortality from all causes and from cardiovascular disease in five populations of Asian origin
    • DECODA Study Group
    • Nakagami T; DECODA Study Group. Hyperglycemia and mortality from all causes and from cardiovascular disease in five populations of Asian origin. Diabetologia 2004; 47: 385-394.
    • (2004) Diabetologia , vol.47 , pp. 385-394
    • Nakagami, T.1
  • 28
    • 0033047374 scopus 로고    scopus 로고
    • Impaired glucose tolerance is a risk factor for cardiovascular disease, but not impaired fasting glucose: The Funagata Diabetes Study
    • DOI 10.2337/diacare.22.6.920
    • Tominaga M, Eguchi H, Manaka H, et al. Impaired glucose tolerance is a risk factor for cardiovascular disease, but not impaired fasting glucose: the Funagata Diabetes Study. Diabetes Care 1999; 22: 920-924. (Pubitemid 29241045)
    • (1999) Diabetes Care , vol.22 , Issue.6 , pp. 920-924
    • Tominaga, M.1    Eguchi, H.2    Manaka, H.3    Igarashi, K.4    Kato, T.5    Sekikawa, A.6
  • 30
    • 59449105276 scopus 로고    scopus 로고
    • Continuous relationship between non-diabetic hyperglycemia and both cardiovascular disease and all-cause mortality: The Australian Diabetes, Obesity, and Lifestyle (AusDiab) study
    • Barr EL, Boyko EJ, Zimmet PZ, et al. Continuous relationship between non-diabetic hyperglycemia and both cardiovascular disease and all-cause mortality: the Australian Diabetes, Obesity, and Lifestyle (AusDiab) study. Diabetologia 2009; 52: 415-424.
    • (2009) Diabetologia , vol.52 , pp. 415-424
    • Barr, E.L.1    Boyko, E.J.2    Zimmet, P.Z.3
  • 33
    • 33644832167 scopus 로고    scopus 로고
    • Postprandial blood glucose is a stronger predictor of cardiovascular events than fasting blood glucose in type 2 diabetes mellitus, particularly in women: Lessons from the San Luigi Gonzaga diabetes study
    • DOI 10.1210/jc.2005-1005
    • Cavalot F, Pettrelli A, Traversa M, et al. Postprandial blood glucose is a stronger predictor of cardiovascular events than fasting blood glucose in type 2 diabetes mellitus, particularly in women: lessons from the San Luigi Gonzaga Diabetes Study. J Clin Endocrinol Metab 2006; 91: 813-819. (Pubitemid 43357744)
    • (2006) Journal of Clinical Endocrinology and Metabolism , vol.91 , Issue.3 , pp. 813-819
    • Cavalot, F.1    Petrelli, A.2    Traversa, M.3    Bonomo, K.4    Fiora, E.5    Conti, M.6    Anfossi, G.7    Costa, G.8    Trovati, M.9
  • 34
    • 59349092016 scopus 로고    scopus 로고
    • Excess glycemic excursions after an oral glucose tolerance test compared with a mixed meal challenge and self-measured home glucose profiles: Is the OGTT a valid predictor of postprandial hyperglycemia and vice versa?
    • Meier JJ, Baller B, Menge BA, et al. Excess glycemic excursions after an oral glucose tolerance test compared with a mixed meal challenge and self-measured home glucose profiles: is the OGTT a valid predictor of postprandial hyperglycemia and vice versa? Diabetes Obes Metab 2009; 11: 213-222.
    • (2009) Diabetes Obes Metab , vol.11 , pp. 213-222
    • Meier, J.J.1    Baller, B.2    Menge, B.A.3
  • 35
    • 48449098502 scopus 로고    scopus 로고
    • Oscillating glucose is more deleterious to endothelial function and oxidative stress than mean glucose in normal and type 2 diabetic patients
    • Ceriello A, Esposito K, Piconi L, et al. Oscillating glucose is more deleterious to endothelial function and oxidative stress than mean glucose in normal and type 2 diabetic patients. Diabetes 2008; 57: 1349-1354.
    • (2008) Diabetes , vol.57 , pp. 1349-1354
    • Ceriello, A.1    Esposito, K.2    Piconi, L.3
  • 36
    • 33645745733 scopus 로고    scopus 로고
    • Activation of oxidative stress by acute Glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes
    • Monnier L, Mas E, Ginet C, et al. Activation of oxidative stress by acute Glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes. JAMA 2006; 295: 1681-1687.
    • (2006) JAMA , vol.295 , pp. 1681-1687
    • Monnier, L.1    Mas, E.2    Ginet, C.3
  • 37
    • 79954631857 scopus 로고    scopus 로고
    • Glucose oscillations, more than constant high glucose, induce p53 activation and a metabolic memory in human endothelial cells
    • Schisano B, Tripathi G, McGee K, et al. Glucose oscillations, more than constant high glucose, induce p53 activation and a metabolic memory in human endothelial cells. Diabetologia 2011; 54: 1219-1226.
    • (2011) Diabetologia , vol.54 , pp. 1219-1226
    • Schisano, B.1    Tripathi, G.2    McGee, K.3
  • 38
    • 33644873949 scopus 로고    scopus 로고
    • Effects of different insulin regimes on postprandial myocardial perfusion defects in type 2 diabetic patients
    • Scognamiglio R, Negut C, de Kreutzenberg SV, et al. Effect of different insulin regimes on postprandial myocardial perfusion defects in type 2 diabetic patients. Diabetes Care 2006; 29: 95-100. (Pubitemid 44033438)
    • (2006) Diabetes Care , vol.29 , Issue.1 , pp. 95-100
    • Scognamiglio, R.1    Negut, C.2    De Kreutzenberg, S.V.3    Tiengo, A.4    Avogaro, A.5
  • 40
    • 33644821275 scopus 로고    scopus 로고
    • Effects of a single administration of acarbose on postprandial glucose excursion and endothelial dysfunction in type 2 diabetic patients: A randomized crossover study
    • DOI 10.1210/jc.2005-1566
    • Shimabukuro M, Higa N, Chinen I, et al. Effects of a single administration of acarbose on post-prandial glucose excursions and endothelial dysfunction in type 2 diabetic patients: a randomized crossover study. J Clin Endocrinol Metab 2006; 91: 837-842. (Pubitemid 43357747)
    • (2006) Journal of Clinical Endocrinology and Metabolism , vol.91 , Issue.3 , pp. 837-842
    • Shimabukuro, M.1    Higa, N.2    Chinen, I.3    Yamakawa, K.4    Takasu, N.5
  • 41
    • 13444273243 scopus 로고    scopus 로고
    • Effects of nateglinide on myocardial microvascular reactivity in Type 2 diabetes mellitus - A randomized study using positron emission tomography
    • DOI 10.1111/j.1464-5491.2004.01371.x
    • Bengel FM, Abletshauser C, Neverve J, et al. Effects of nateglinide on myocardial microvascular reactivity in Type 2 diabetes mellitus - a randomized study using positron emission tomography. Diabetic Med 2004; 22: 158-163. (Pubitemid 40204321)
    • (2005) Diabetic Medicine , vol.22 , Issue.2 , pp. 158-163
    • Bengel, F.M.1    Abletshausert, C.2    Neverve, J.3    Schnellt, O.4    Nekolla, S.G.5    Standl, E.6    Schwaiger, M.7
  • 42
    • 77957953067 scopus 로고    scopus 로고
    • Effects of acarbose on the acceleration of postprandial hyperglycemia-induced pathological changes induced by intermittent hypoxia in lean mice
    • Miyamura M, Schnell O, Yamashita C, et al. Effects of acarbose on the acceleration of postprandial hyperglycemia-induced pathological changes induced by intermittent hypoxia in lean mice. J Pharmacol Sci 2010; 114: 32-40.
    • (2010) J Pharmacol Sci , vol.114 , pp. 32-40
    • Miyamura, M.1    Schnell, O.2    Yamashita, C.3
  • 43
    • 0037097039 scopus 로고    scopus 로고
    • Acarbose for prevention of type 2 diabetes mellitus: The STOP-NIDDM randomised trial
    • DOI 10.1016/S0140-6736(02)08905-5
    • Chiasson JL, Josse RG, Gomis R, et al. Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomized trial. Lancet 2002; 359: 2072-2077. (Pubitemid 34680970)
    • (2002) Lancet , vol.359 , Issue.9323 , pp. 2072-2077
    • Chiasson, J.-L.1    Josse, R.G.2    Gomis, R.3    Hanefeld, M.4    Karasik, A.5    Laakso, M.6
  • 44
    • 0038455703 scopus 로고    scopus 로고
    • Acarbose Treatment and the Risk of Cardiovascular Disease and Hypertension in Patients with Impaired Glucose Tolerance: The STOP-NIDDM Trial
    • DOI 10.1001/jama.290.4.486
    • Chiasson JL, Josse RG, Gomis R, et al. Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impairedglucose tolerance: the STOP-NIDDM trial. JAMA 2003; 290: 486-494. (Pubitemid 37430502)
    • (2003) Journal of the American Medical Association , vol.290 , Issue.4 , pp. 486-494
    • Chiasson, J.-L.1    Josse, R.G.2    Gomis, R.3    Hanefeld, M.4    Karasik, A.5    Laakso, M.6
  • 45
    • 84863450924 scopus 로고    scopus 로고
    • Acarbose slows progression of intima-media thickness of the carotid arteries in subjects with impaired glucose tolerance
    • Hanefeld M, Chiasson JL, Koehler C, et al. Acarbose slows progression of intima-media thickness of the carotid arteries in subjects with impaired glucose tolerance. Stroke 2004; 25: 10-16.
    • (2004) Stroke , vol.25 , pp. 10-16
    • Hanefeld, M.1    Chiasson, J.L.2    Koehler, C.3
  • 46
    • 0346727578 scopus 로고    scopus 로고
    • Acarbose reduces the risk for myocardial infarction in type 2 diabetic patients: Meta-analysis of seven long-term studies
    • DOI 10.1016/S0195-668X(03)00468-8
    • Hanefeld M, Cagatay M, Petrowitsch T, et al. Acarbose reduces the risk for myocardial infarction in type 2 diabetic patients: meta-analysis of seven long-term studies. Eur Heart J 2004; 25: 10-16. (Pubitemid 38055587)
    • (2004) European Heart Journal , vol.25 , Issue.1 , pp. 10-16
    • Hanefeld, M.1    Cagatay, M.2    Petrowitsch, T.3    Neuser, D.4    Petzinna, D.5    Rupp, M.6
  • 47
    • 0036395954 scopus 로고    scopus 로고
    • Effects on blood pressure of the alpha-glucosidase inhibitor acarbose compared with the insulin enhancer glibenclamide in patients with hypertension and type 2 diabetes mellitus
    • Rosenthal JH and Mauersberger H. Effects on blood pressure of the alpha-glucosidase inhibitor acarbose compared with the insulin enhancer glibenclamide in patients with hypertension and typ 2 diabetes mellitus. Clin Drug Invest 2002; 22: 695-701. (Pubitemid 35155504)
    • (2002) Clinical Drug Investigation , vol.22 , Issue.10 , pp. 695-701
    • Rosenthal, J.H.1    Mauersberger, H.2
  • 48
    • 65449150953 scopus 로고    scopus 로고
    • Voglibose for prevention of type 2 diabetes mellitus: A randomized, double-blind tiral in Japanese individuals with impaired glucose tolerance
    • Kawamori R, Tajima N, Iwamoto Y, et al. Voglibose for prevention of type 2 diabetes mellitus: a randomized, double-blind tiral in Japanese individuals with impaired glucose tolerance. Lancet 2009; 373: 1607-1614.
    • (2009) Lancet , vol.373 , pp. 1607-1614
    • Kawamori, R.1    Tajima, N.2    Iwamoto, Y.3
  • 49
    • 77951473452 scopus 로고    scopus 로고
    • Effect of nateglinide on the incidence of diabetes and cardiovascular events
    • NAVIGATOR Study Group
    • Holman RR, Haffner SM, McMurray JJ, et al. NAVIGATOR Study Group. Effect of nateglinide on the incidence of diabetes and cardiovascular events. N Engl J Med 2010; 362: 1463-1476.
    • (2010) N Engl J Med , vol.362 , pp. 1463-1476
    • Holman, R.R.1    Haffner, S.M.2    McMurray, J.J.3
  • 50
    • 64749114318 scopus 로고    scopus 로고
    • Effects of prandial versus fasting glycemia on cardiovascular outcomes in type 2 diabetes: The HEART2D trial
    • Raz I, Wilson PWF, Strojek K, et al. Effects of prandial versus fasting glycemia On cardiovascular outcomes in type 2 diabetes: the HEART2D trial. Diabetes Care 2009; 32: 381-386.
    • (2009) Diabetes Care , vol.32 , pp. 381-386
    • Raz, I.1    Wilson, P.W.F.2    Strojek, K.3
  • 51
    • 84863490086 scopus 로고    scopus 로고
    • launched 11 April accessed 15 December 2011
    • Acarbose Cardiovascular Evaluation, launched 11 April 2008. http//www.dtu.ox.ac.uk/ace/index (accessed 15 December 2011).
    • (2008) Acarbose Cardiovascular Evaluation
  • 52
    • 79954621531 scopus 로고    scopus 로고
    • International Noninterventional study of acarbose treatment in patients with typ 2 diabetes mellitus
    • Li C, Hung Y-J, Qamruddin K, et al. International Noninterventional study of acarbose treatment in patients with typ 2 diabetes mellitus. Diabetes Res Clin Pract 2011; 92: 57-64.
    • (2011) Diabetes Res Clin Pract , vol.92 , pp. 57-64
    • Li, C.1    Hung, Y.-J.2    Qamruddin, K.3
  • 53
    • 80052706816 scopus 로고    scopus 로고
    • The beneficial effect of alpha-glucosidase inhibitor on glucose variability compared withsulfonyurea in Taiwanese type 2 diabetic patients inadequatelycontrolled with metformin: Preliminary data
    • Epub ahead of print 1 August 2011, DOI: 10.1016/j.jdiacomp. 2011.06.004
    • Lin S-D, Wang J-S, Hsu S-R, et al. The beneficial effect of alpha-glucosidase inhibitor on glucose variability compared withsulfonyurea in Taiwanese type 2 diabetic patients inadequatelycontrolled with metformin: Preliminary data. J Diabet Complications. Epub ahead of print 1 August 2011, DOI: 10.1016/j.jdiacomp. 2011.06.004.
    • J Diabet Complications
    • Lin, S.-D.1    Wang, J.-S.2    Hsu, S.-R.3
  • 54
    • 35048874614 scopus 로고    scopus 로고
    • Acarbose and metabolic control in patients with type 2 diabetes with newly initiated insulin therapy
    • DOI 10.1111/j.1463-1326.2006.00666.x
    • Schnell O, Mertes G and Standl E. Acarbose and metabolic control in patients with type 2 diabetes with newly initiated insulin therapy. Diabetes Obes Metab 2007; 6: 853-858. (Pubitemid 47555206)
    • (2007) Diabetes, Obesity and Metabolism , vol.9 , Issue.6 , pp. 853-858
    • Schnell, O.1    Mertes, G.2    Standl, E.3


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