Inhibition of Na-K + -2Cl - cotransporter isoform 1 accelerates temozolomidemediated apoptosis in glioblastoma cancer cells

Cellular Physiology and Biochemistry

Volumn 30, Issue 1, 2012, Pages 33-48

  Algharabil, Jehad ^a   Kintner, Douglas B ^b   Wang, Qiwei ^b   Begum, Gulnaz ^a   Clark, Paul A ^b   Yang, Sung Sen ^c   Lin, Shih Hua ^c   Kahle, Kristopher T ^d   Kuo, John S ^b   Sun, Dandan ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Apoptosis; Apoptotic volume decrease; Bumetanide; Caspase; Glioblastoma multiforme; Temozolomide

Indexed keywords

BUMETANIDE; CASPASE 3; CASPASE 8; PROTEIN KINASE WNK1; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; SODIUM POTASSIUM CHLORIDE COTRANSPORTER 1; TEMOZOLOMIDE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER STEM CELL; CELL VOLUME; CONTROLLED STUDY; ELECTROCHEMICAL ANALYSIS; ENZYME ACTIVATION; ENZYME INHIBITION; GLIOBLASTOMA; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

EID: 84863436675     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000339047     Document Type: Article

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