In vivo monitoring of protein-bound and free NADH during ischemia by nonlinear spectral imaging microscopy

Biomedical Optics Express

Volumn 2, Issue 5, 2011, Pages 1030-1039

  Palero, Jonathan A ^a,b   Bader, Arjen N ^a   de Bruijn, Henriëtte S ^c   van den Heuvel, Angélique van der Ploeg ^c   Sterenborg, Henricus J C M ^c   Gerritsen, Hans C ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b ICFO INSTITUT DE CIENCIES FOTONIQUES   (Spain)

^c ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDES; DYNAMIC RESPONSE; PROTEINS;

HIGH SPECTRAL RESOLUTION; IN-VIVO; LINEAR SPECTRAL UNMIXING; LIVING ANIMALS; MOUSE KERATINOCYTES; NAD(P)H; NICOTINAMIDE ADENINE DINUCLEOTIDES; SPECTRAL IMAGE DATA; SPECTRAL IMAGING; SPECTROSCOPIC INVESTIGATIONS; TIME INTERVAL; TWO-PHOTON EXCITED FLUORESCENCE;

SPECTROSCOPY;

ANIMALIA;

EID: 84863428199     PISSN: None     EISSN: 21567085     Source Type: Journal    
DOI: 10.1364/BOE.2.001030     Document Type: Article

References (30)

1. B. Chance, P. Cohen, F. Jobsis, and B. Schoener, "Intracellular oxidation-reduction states in vivo," Science 137(3529), 499-508 (1962).
2. W. R. Zipfel, R. M. Williams, R. Christie, A. Y. Nikitin, B. T. Hyman, and W. W. Webb, "Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation," Proc. Natl. Acad. Sci. U.S.A. 100(12), 7075-7080 (2003).
3. J. A. Palero, H. S. de Bruijn, A. van der Ploeg van den Heuvel, H. J. Sterenborg, and H. C. Gerritsen, "Spectrally resolved multiphoton imaging of in vivo and excised mouse skin tissues," Biophys. J. 93(3), 992-1007 (2007).
4. J. A. Palero, H. S. de Bruijn, A. van der Ploeg-van den Heuvel, H. J. Sterenborg, and H. C. Gerritsen, "In vivo nonlinear spectral imaging in mouse skin," Opt. Express 14(10), 4395-4402 (2006).
5. E. C. Rothstein, S. Carroll, C. A. Combs, P. D. Jobsis, and R. S. Balaban, "Skeletal muscle NAD(P)H twophoton fluorescence microscopy in vivo: topology and optical inner filters," Biophys. J. 88(3), 2165-2176 (2005).
6. M. C. Skala, K. M. Riching, A. Gendron-Fitzpatrick, J. Eickhoff, K. W. Eliceiri, J. G. White, and N. Ramanujam, "In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia," Proc. Natl. Acad. Sci. U.S.A. 104(49), 19494-19499 (2007).
7. H. D. Vishwasrao, A. A. Heikal, K. A. Kasischke, and W. W. Webb, "Conformational dependence of intracellular NADH on metabolic state revealed by associated fluorescence anisotropy," J. Biol. Chem. 280(26), 25119-25126 (2005).
8. V. K. Ramanujan, J. A. Jo, G. Cantu, and B. A. Herman, "Spatially resolved fluorescence lifetime mapping of enzyme kinetics in living cells," J. Microsc. 230(3), 329-338 (2008).
9. V. V. Ghukasyan and F.-J. Kao, "Monitoring cellular metabolism with fluorescence lifetime of reduced nicotinamide adenine dinucleotide," J. Phys. Chem. C 113(27), 11532-11540 (2009).
10. M. C. Skala, K. M. Riching, D. K. Bird, A. Gendron-Fitzpatrick, J. Eickhoff, K. W. Eliceiri, P. J. Keely, and N. Ramanujam, "In vivo multiphoton fluorescence lifetime imaging of protein-bound and free nicotinamide adenine dinucleotide in normal and precancerous epithelia," J. Biomed. Opt. 12(2), 024014 (2007).
11. Q. Yu and A. A. Heikal, "Two-photon autofluorescence dynamics imaging reveals sensitivity of intracellular NADH concentration and conformation to cell physiology at the single-cell level," J. Photochem. Photobiol. B 95(1), 46-57 (2009).
12. D. Li, W. Zheng, and J. Y. Qu, "Time-resolved spectroscopic imaging reveals the fundamentals of cellular NADH fluorescence," Opt. Lett. 33(20), 2365-2367 (2008).
13. D. K. Bird, L. Yan, K. M. Vrotsos, K. W. Eliceiri, E. M. Vaughan, P. J. Keely, J. G. White, and N. Ramanujam, "Metabolic mapping of MCF10A human breast cells via multiphoton fluorescence lifetime imaging of the coenzyme NADH," Cancer Res. 65(19), 8766-8773 (2005).
14. J. A. Palero, G. Latouche, H. S. de Bruijn, A. van der Ploeg van den Heuvel, H. J. Sterenborg, and H. C. Gerritsen, "Design and implementation of a sensitive high-resolution nonlinear spectral imaging microscope," J. Biomed. Opt. 13(4), 044019 (2008).
15. J. Palero, "Nonlinear spectral imaging microscopy," Imaging Microsc. 11(1), 22-25 (2009).
16. P. L. T. M. Frederix, M. A. H. Asselbergs, W. G. J. H. M. Van Sark, D. J. Van den Heuvel, W. Hamelink, E. L. de Beer, and H. C. Gerritsen, "High sensitivity spectrograph for use in fluorescence microscopy," Appl. Spectrosc. 55(8), 1005-1012 (2001).
17. A. Esposito, A. N. Bader, S. C. Schlachter, D. J. van den Heuvel, G. S. K. Schierle, A. R. Venkitaraman, C. F. Kaminski, and H. C. Gerritsen, "Design and application of a confocal microscope for spectrally resolved anisotropy imaging," Opt. Express 19(3), 2546-2555 (2011).
18. J. A. Palero, H. S. de Bruijn, A. van der Ploeg van den Heuvel, H. J. Sterenborg, H. van Weelden, and H. C. Gerritsen, "In vivo nonlinear spectral imaging microscopy of visible and ultraviolet irradiated hairless mouse skin tissues," Photochem. Photobiol. Sci. 7(11), 1422-1425 (2008).
19. A. N. Bader, A.-M. Pena, C. Johan van Voskuilen, J. A. Palero, F. Leroy, A. Colonna, and H. C. Gerritsen, "Fast nonlinear spectral microscopy of in vivo human skin," Biomed. Opt. Express 2(2), 365-373 (2011).
20. G. Weagle, P. E. Paterson, J. Kennedy, and R. Pottier, "The nature of the chromophore responsible for naturally occurring fluorescence in mouse skin," J. Photochem. Photobiol. B 2(3), 313-320 (1988).
21. A. Amelink and H. J. Sterenborg, "Measurement of the local optical properties of turbid media by differential path-length spectroscopy," Appl. Opt. 43(15), 3048-3054 (2004).
22. J. A. Gardecki and M. Maroncelli, "Set of secondary emission standards for calibration of the spectral responsivity in emission spectroscopy," Appl. Spectrosc. 52(9), 1179-1189 (1998).
23. J. R. Lakowicz, H. Szmacinski, K. Nowaczyk, and M. L. Johnson, "Fluorescence lifetime imaging of free and protein-bound NADH," Proc. Natl. Acad. Sci. U.S.A. 89(4), 1271-1275 (1992).
24. R. Richards-Kortum and E. Sevick-Muraca, "Quantitative optical spectroscopy for tissue diagnosis," Annu. Rev. Phys. Chem. 47(1), 555-606 (1996).
25. K. Blinova, R. L. Levine, E. S. Boja, G. L. Griffiths, Z. D. Shi, B. Ruddy, and R. S. Balaban, "Mitochondrial NADH fluorescence is enhanced by complex I binding," Biochemistry 47(36), 9636-9645 (2008).
26. N. D. Evans, L. Gnudi, O. J. Rolinski, D. J. Birch, and J. C. Pickup, "Glucose-dependent changes in NAD(P)H-related fluorescence lifetime of adipocytes and fibroblasts in vitro: potential for non-invasive glucose sensing in diabetes mellitus," J. Photochem. Photobiol. B 80(2), 122-129 (2005).
27. G. Ronquist, A. Andersson, N. Bendsoe, and B. Falck, "Human epidermal energy metabolism is functionally anaerobic," Exp. Dermatol. 12(5), 572-579 (2003).
28. M. Stücker, A. Struk, P. Altmeyer, M. Herde, H. Baumgärtl, and D. W. Lübbers, "The cutaneous uptake of atmospheric oxygen contributes significantly to the oxygen supply of human dermis and epidermis," J. Physiol. 538(3), 985-994 (2002).
29. T. Galeotti, G. D. van Rossum, D. H. Mayer, and B. Chance, "On the fluorescence of NAD(P)H in whole-cell preparations of tumours and normal tissues," Eur. J. Biochem. 17(3), 485-496 (1970).
30. Z. Abramovic, M. Sentjurc, J. Kristl, N. Khan, H. Hou, and H. M. Swartz, "Influence of different anesthetics on skin oxygenation studied by electron paramagnetic resonance in vivo," Skin Pharmacol. Physiol. 20(2), 77-84 (2007).