Steroids from Commiphora mukul display antiproliferative effect against human prostate cancer PC3 cells via induction of apoptosis

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 14, 2012, Pages 4801-4806

  Shen, Tao ^a   Zhang, Li ^b   Wang, Yan Yan ^a   Fan, Pei Hong ^a   Wang, Xiao Ning ^a   Lin, Zhao Min ^a   Lou, Hong Xiang ^a  

^a SHANDONG UNIVERSITY   (China)

^b Jinan Second People's Hospital   (China)

Author keywords

Antiproliferative; Apoptosis; Burseraceae; Commiphora mukul; Prostate cancer; Steroid

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; HERBACEOUS AGENT; PLANT RESIN; PROTEIN BAX; PROTEIN BCL 2; STEROID; STIGMASTA 5,22E DIENE 3BETA,11ALPHA DIOL; STIGMASTA 5,22E DIENE 3BETA,7ALPHA,11ALPHA TRIOL; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; COMMIPHORA; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; FLUORESCENCE CORRELATION SPECTROSCOPY; G1 PHASE CELL CYCLE CHECKPOINT; G2 PHASE CELL CYCLE CHECKPOINT; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR MULTIPLE QUANTUM COHERENCE; HUMAN; HUMAN CELL; IC 50; M PHASE CELL CYCLE CHECKPOINT; MEDICINAL PLANT; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PROSTATE CANCER; PROTEIN EXPRESSION;

APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; COMMIPHORA; HUMANS; MALE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROSTATIC NEOPLASMS; STEROIDS; STRUCTURE-ACTIVITY RELATIONSHIP;

BURSERACEAE; COMMIPHORA WIGHTII;

EID: 84863424804     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.05.052     Document Type: Article

References (40)

1. X. Ding, and J.L. Staudinger J. Pharmacol. Exp. Ther. 314 2005 120
2. N. Khanna, D. Arora, S. Halder, A.K. Mehta, G.R. Garg, S.B. Sharma, and P. Mahajan Indian J. Exp. Biol. 48 2010 299
3. B.B. Singh, L.C. Mishra, S.P. Vinjamury, N. Aquilina, V.J. Singh, and N. Shepard Altern. Ther. Health Med. 9 2003 74
4. R.B. Singh, M.A. Niaz, and S. Ghosh Cardiovasc. Drugs Ther. 8 1994 659
5. V.D. Patil, U.R. Nayak, and S. Dev Tetrahedron 29 1973 341
6. V. Kumar, and S. Dev Tetrahedron 43 1987 5933
7. V.D. Patil, U.R. Nayak, and S. Dev Tetrahedron 29 1973 1595
8. R.S. Prasad, and S. Dev Tetrahedron 32 1976 1437
9. A.G. Bajaj, and S. Dev Tetrahedron 38 1982 2949
10. V.D. Patil, U.R. Nayak, and S. Dev Tetrahedron 28 1972 2341
11. H. Matsuda, T. Morikawa, S. Ando, H. Oominami, T. Murakami, I. Kimura, and M. Yoshikawa Chem. Pharm. Bull. 52 2004 1200
12. I. Kimura, M. Yoshikawa, S. Kobayashi, Y. Sugihara, M. Suzuki, H. Oominami, T. Murakami, H. Matsuda, and V.V. Doiphode Bioorg. Med. Chem. Lett. 11 2001 985
13. T. Shen, and H.-X. Lou Chem. Biodivers. 5 2008 540
14. S. Shishodia, G. Sethi, K.S. Ahn, and B.B. Aggarwal Biochem. Pharmacol. 74 2007 118
15. S.V. Singh, Y. Zeng, D. Xiao, V.G. Vogel, J.B. Nelson, R. Dhir, and Y.B. Tripathi Mol. Cancer Ther. 4 2005 1747
16. S.V. Singh, S. Choi, Y. Zeng, E.R. Hahm, and D. Xiao Cancer Res. 67 2007 7439
17. W. Bursch, F. Oberhammer, and R. Schulte-Hermann Trends Pharmacol. Sci. 13 1992 245
18. M.I. Johnson, and F.C. Hamdy Oncol. Rep. 5 1998 553
19. T. Shen, W. Wan, H. Yuan, F. Kong, H. Guo, P. Fan, and H. Lou Phytochemistry 68 2007 1331
20. T. Shen, H.-Q. Yuan, W.-Z. Wan, X.-L. Wang, X.-N. Wang, M. Ji, and H.-X. Lou J. Nat. Prod. 71 2008 81
21. T. Shen, W.-Z. Wan, X.-N. Wang, L.-M. Sun, H.-Q. Yuan, X.-L. Wang, M. Ji, and H.-X. Lou Helv. Chim. Acta 91 2008 881
22. T. Shen, W.-Z. Wan, X.-N. Wang, H.-Q. Yuan, M. Ji, and H.-X. Lou Helv. Chim. Acta 92 2009 645
23. X.L. Wang, F. Kong, T. Shen, C.Y.F. Young, H.Q. Yuan, and H.X. Lou Acta Pharmacol. Sinica 32 2011 338
24. L. Yan, L. Xu, Z. Zou, and S. Yang Zhong Cao Yao 38 2007 340
25. M. Ando, K. Arai, K. Kikuchi, and K. Isogai J. Nat. Prod. 57 1994 1189
26. J. Pascual-T, I.S. Bellido, and M.S. González Tetrahedron 36 1980 371
27. K.A.E. Sayed, and M.T. Hamann J. Nat. Prod. 59 1996 687
28. K. Takeda, I. Horibe, and H. Minato J. Chem. Soc. (C) 1968 569
29. A.S.R. Anjaneyulu, and P.M. Gowri Indian J. Chem., Sect. B 39 2000 773
30. S. Weber, J. Puripattanavong, V. Brecht, and A.W. Frahm J. Nat. Prod. 63 2000 636
31. H.-F. Luo, Q. Li, S. Yu, T.M. Badger, and N. Fang J. Nat. Prod. 68 2005 94
32. A. Madaio, V. Piccialli, D. Sica, and G. Corriero J. Nat. Prod. 52 1989 952
33. M. Ishibashi, E. Yamagishi, and J. Kobayashi Chem. Pharm. Bull. 45 1994 1435
34. H. Liu, Y.-Q. Liu, Y.-Q. Liu, A.-H. Xu, C.Y.F. Young, H.-Q. Yuan, and H.-X. Lou Chem. Biol. Interact. 188 2010 598
35. H.-Q. Yuan, F. Kong, X.L. Wang, C.Y.F. Young, X.-Y. Hu, and H.-X. Lou Biochem. Pharmacol. 75 2008 2112
36. J.-C. Su, K.-L. Lin, C.-M. Chien, C.-M. Lu, Y.-L. Chen, L.-S. Chang, and S.-R. Lin Life Sci. 85 2009 505
37. S. Prasad, J. Kaur, P. Roy, N. Kalra, and Y. Shukla Life Sci. 81 2007 1323
38. S.J. White, L.M. Kasman, M.M. Kelly, P. Lu, L. Spruill, P.J. McDermott, and C. Voelkel-Johnson Free Radic. Biol. Med. 43 2007 1313
39. P.M. O'Connor, D.K. Ferris, M. Pagano, G. Draetta, J. Pines, T. Hunter, D.L. Longo, and K.W. Kohn J. Biol. Chem. 268 1993 8298
40. M.M. Kelly, B.D. Hoel, and C. Voelkel-Johnson Cancer Biol. Ther. 1 2002 520