Sesquiterpenoids from myrrh inhibit androgen receptor expression and function in human prostate cancer cells

Acta Pharmacologica Sinica

Volumn 32, Issue 3, 2011, Pages 338-344

  Wang, Xiao Ling ^a   Kong, Feng ^a   Shen, Tao ^a   Young, Charles Yf ^b   Lou, Hong Xiang ^a   Yuan, Hui Qing ^a  

^a SHANDONG UNIVERSITY   (China)

^b DEPARTMENT OF UROLOGY   (United States)

Author keywords

androgen receptor; germacrane sesquiterpenoids; myrrh; prostate carcinoma cell lines

Indexed keywords

2 METHOXY 5 ACETOXY FURANOGERMACR 1(10) EN 6 ONE; 2 METHOXY 8,12 EPOXYGERMACRA 1(10),7,11 TRIEN 6 ONE; ANDROGEN RECEPTOR; ANDROGEN RECEPTOR COACTIVATOR 70; PROSTATE SPECIFIC ANTIGEN; SESQUITERPENOID; STEROID RECEPTOR COACTIVATOR 1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOGENESIS; CELL STRAIN LNCAP; CONTROLLED STUDY; DRUG DETERMINATION; DRUG MECHANISM; DRUG SCREENING; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE ACTIVITY; GENE EXPRESSION REGULATION; HORMONE RESPONSIVE ELEMENT; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MALE; PROMOTER REGION; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN TRANSPORT; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR BLOCKING; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION TERMINATION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; COMMIPHORA; HUMANS; MALE; MOLECULAR TARGETED THERAPY; PHYTOTHERAPY; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN; SESQUITERPENES; TERPENES;

EID: 79952407593     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2010.219     Document Type: Article

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